Reparative properties of the traditional Chinese medicine Cordyceps sinensis (Chinese caterpillar mushroom) using HT29 cell culture and rat gastric damage models of injury

British Journal of Nutrition

Volumn 105, Issue 9, 2011, Pages 1303-1310

  Marchbank, Tania ^a   Ojobo, Ehighale ^a   Playford, Christopher J ^a   Playford, Raymond J ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Gut growth; Injury; Nutriceuticals; Repair

Indexed keywords

ALCOHOL; CORDYCEPS SINENSIS EXTRACT; EPIDERMAL GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN HT29; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; RAT; STOMACH INJURY; TISSUE REPAIR;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL MOVEMENT; CELL PROLIFERATION; CORDYCEPS; DIETARY SUPPLEMENTS; DRUGS, CHINESE HERBAL; HT29 CELLS; HUMANS; INDOMETHACIN; MEDICINE, CHINESE TRADITIONAL; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RESTRAINT, PHYSICAL; STOMACH DISEASES;

BASIDIOMYCOTA; CORDYCEPS SINENSIS; RATTUS;

EID: 79956000126     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114510005118     Document Type: Article

References (32)

1. Ghosh S & Playford RJ (2003) Bioactive natural compounds for the treatment of gastrointestinal disorders. Clin Sci 104, 547-556. (Pubitemid 36713843)
2. Dong CH & Yao YJ (2005) Nutritional requirements of mycelial growth of Cordyceps sinensis in submerged culture. J Appl Microbiol 99, 483-492.
3. Zhong JJ & Xiao JH (2009) Secondary metabolites from higher fungi: discovery, bioactivity, and bioproduction. Adv Biochem Eng Biotechnol 113, 79-150.
4. Chen Y, Guo H, Du Z, et al. (2009) Ecology-based screen identifies new metabolites from a Cordyceps-colonizing fungus as cancer cell proliferation inhibitors and apoptosis inducers. Cell Prolif 42, 838-847.
5. Chen S, Li Z, Krochmal R, et al. (2010) Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial. J Altern Complement Med 16, 585-590.
6. Koh JH, Kim KM, Kim JM, et al. (2003) Antifatigue and antistress effect of the hot-water fraction from mycelia of Cordyceps sinensis. Biol Pharm Bull 26, 691-694.
7. Yamaguchi Y, Kagota S, Nakamura K, et al. (2000) Inhibitory effects of water extracts from fruiting bodies of cultured Cordyceps sinensis on raised serum lipid peroxide levels and aortic cholesterol deposition in atherosclerotic mice. Phytother Res 14, 650-652.
8. Colson SN, Wyatt FB, Johnston DL, et al. (2005) Cordyceps sinensis- and Rhodiola rosea-based supplementation in male cyclists and its effect on muscle tissue oxygen saturation. J Strength Cond Res 19, 358-363. (Pubitemid 40807086)
9. Fogh J, Fogh JM & Orfeo T (1977) One hundred and twentyseven cultured human tumor cell lines producing tumors in nude mice. J Natl Cancer Inst 59, 221-226. (Pubitemid 8144854)
10. Brown RE, Jarvis KL & Hyland KJ (1989) Protein measurement using bicinchoninic acid: elimination of interfering substances. Anal Biochem 180, 136-139. (Pubitemid 19200575)
11. Marchbank T, Mahmood A, Fitzgerald AJ, et al. (2007) Human pancreatic secretory trypsin inhibitor stabilizes intestinal mucosa against noxious agents. Am J Pathol 171, 1462-1473. (Pubitemid 350158308)
12. Marchbank T, Weaver G, Nilsen-Hamilton M, et al. (2009) Pancreatic secretory trypsin inhibitor is a major motogenic and protective factor in human breast milk. Am J Physiol Gastrointest Liver Physiol 296, G697-G703.
13. Nakayama GR, Caton MC, Nova MP, et al. (1997) Assessment of the Alamar Blue assay for cellular growth and viability in vitro. J Immunol 204, 205-208. (Pubitemid 27262014)
14. Fitzgerald AJ, Rai PS, Marchbank T, et al. (2005) Reparative properties of a commercial fish protein hydrolysate preparation. Gut 54, 775-781. (Pubitemid 40732093)
15. Playford RJ, Belo A, Poulsom R, et al. (2006) Effects of mouse and human lipocalin homologues 24p3/lcn2 and neutrophil gelatinase-associated lipocalin on gastrointestinal mucosal integrity and repair. Gastroenterology 131, 809-817. (Pubitemid 44307059)
16. Playford RJ, Vesey DA, Haldane, et al. (1991) Dosedependent effects of fentanyl on indomethacin-induced gastric damage. Digestion 49, 198-203.
17. Sloan AE (2002) The top 10 functional food trends: the next generation. Food Technol 56, 32-57.
18. Wright TH, Yazbeck R, Lymn KA, et al. (2009) The herbal extract, Iberogast, improves jejunal integrity in rats with 5-fluorouracil (5-FU)-induced mucositis. Cancer Biol Ther 8, 923-929.
19. Cheah KY, Howarth GS, Yazbeck R, et al. (2009) Grape seed extract protects IEC-6 cells from chemotherapy-induced cytotoxicity and improves parameters of small intestinal mucositis in rats with experimentally-induced mucositis. Cancer Biol Ther 8, 382-390.
20. Graziani G, D'Argenio G, Tuccillo C, et al. (2005) Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo. Gut 54, 193-200. (Pubitemid 40139232)
21. D'Argenio G, Mazzone G, Tuccillo C, et al. (2008) Apple polyphenol extracts prevent aspirin-induced damage to the rat gastric mucosa. Br J Nutr 100, 1228-1236.
22. Playford RJ, Floyd DN, Macdonald CE, et al. (1999) Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. Gut 44, 653-658. (Pubitemid 29195912)
23. Mahmood A, FitzGerald AJ, Marchbank T, et al. (2007) Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes. Gut 56, 168-175.
24. Bjarnason I, Zanelli G, Prouse P, et al. (1987) Blood and protein loss via small intestinal inflammation induced by nonsteroidal antiinflammatory drugs. Lancet ii 711-714. (Pubitemid 17125695)
25. Levi S & Shaw-Smith C (1994) Non-steroidal anti-inflammatory drugs: how do they damage the gut? Br J Rheumatol 33, 605-612. (Pubitemid 24222110)
26. Akaki J, Matsui Y, Kojima H, et al. (2009) Structural analysis of monocyte activation constituents in cultured mycelia of Cordyceps sinensis. Fitoterapia 80, 182-187.
27. Liu WC, Wang SC, Tsai ML, et al. (2006) Protection against radiation-induced bone marrow and intestinal injuries by Cordyceps sinensis, a Chinese herbal medicine. Radiat Res 166, 900-907.
28. Belo A, Marchbank T, Fitzgerald A, et al. (2006) Gastroprotective effects of oral nucleotide administration. Gut 55, 165-171. (Pubitemid 43117272)
29. Leung PH, Zhang QX & Wu JY (2006) Mycelium cultivation, chemical composition and antitumour activity of a Tolypocladium sp. fungus isolated from wild Cordyceps sinensis. J Appl Microbiol 101, 275-283. (Pubitemid 44060407)
30. Cunningham KG, Manson W, Spring FS, et al. (1950) Cordycepin, a metabolic product isolated from cultures of Cordyceps militaris (Linn.). Nature 166, 949.
31. Guo FQ, Li A, Huang LF, et al. (2006) Identification and determination of nucleosides in Cordyceps sinensis and its substitutes by high performance liquid chromatography with mass spectrometric detection. J Pharm Biomed Anal 40, 623-630. (Pubitemid 43227386)
32. Playford RJ, Batten JJ, Freeman TC, et al. (1991) Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol. Gut 32, 1396-1400.