Bovine colostrum is a health food supplement which prevents NSAID induced gut damage

Gut

Volumn 44, Issue 5, 1999, Pages 653-658

  Playford, R J ^a   Floyd, D N ^a   Macdonald, C E ^a   Calnan, D P ^a   Adenekan, R O ^b   Johnson, W ^c   Goodlad, R A ^b   Marchbank, T ^a  

^a LEICESTER GENERAL HOSPITAL   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c Sci Hosp Supplies Intl Ltd   (United Kingdom)

Author keywords

Gastrointestinal tract; Intestinal injury; Nutrition; Repair

Indexed keywords

NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL MILK; CATTLE; CELL MIGRATION; CELL PROLIFERATION; COLOSTRUM; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIGESTIVE SYSTEM INJURY; DRUG EFFICACY; DRUG INDUCED DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; WOUND HEALING;

EID: 0033043993     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.44.5.653     Document Type: Article

References (26)

1. 1 Allison MC, Allan G, Howatson AG, et al. Gastrointestinal damage associated with the use of non-steroidal anti-inflammatory drugs. N Engl J Med 1992;327:749-54.
2. 2 Bjarnason I, Zanelli G, Smith T, et al. Non-steroidal anti-inflammatory drug induced intestinal inflammation in humans. Gastraenterology 1987;93:480-9.
3. 3 Bjarnason I. Non-steroidal anti-inflammatory drug induced small intestinal inflammation in man. In: Pounder R, ed. Recent advances in gastroenterology. Vol 7. London: Churchill Livingstone Press, 1988:23-46.
4. 4 Pastuszak AL, Schuler L, Speck-Martin CE, et al. Use of misoprostol during pregnancy and Mobius' syndrome in infants. N Engl J Med 1998;338:1881-5.
5. 5 Xu RJ. Development of the newborn GI tract and its relation to colostrum/milk intake: a review. Reprod Fertil Dev 1996;8:35-48.
6. 6 Xanthou M, Bines J, Walker WA. Human milk and intestinal host defence in newborns: an update. In: Advances in paediatrics. Vol 42. Moseby Year Book Inc., 1995:171-200.
7. 7 Playford RJ, Vesey DA, Haldane S, et al. Dose dependant effects of fentanyl on indomethacin induced gastric damage. Digestion 1991;49:198-203.
8. 8 Playford RJ, Marchbank T, Chinnery R, et al. Human spasmolytic polypeptide is a cytoprotective agent which stimulates cell migration. Gastroenterology 1995;108:108-16.
9. 9 Playford RJ, Marchbank T, Goodlad RA, et al. Transgenic mice which overexpress the human trefoil peptide pS2, have an increased resistance to intestinal damage. Proc Natl Acad Sci 1996;93:2137-42.
10. 10 Steimer KS, Packard R, Holden D, et al. The serum free growth of cultured cells in bovine colostrum and in milk obtained later in the lactation period. J Cell Physiol 1981;109:223-34.
11. 11 Simmen FA, Cera KR, Mahan DC. Stimulation by colostrum or mature milk of gastrointestinal tissue development in newborn pigs. J Anim Sci 1990;68:3596-603.
12. 12 Svanes K, Itoh S, Takeuchi K, et al. Restitution of the surface epithelium of the in vitro frog gastric mucosa after damage with hypermolar sodium chloride. Gastroenterology 1982;82:1409-26.
13. 13 Rogers M-L, Goddard C, Regester GO, et al. Transforming growth factor β in bovine milk: concentration, stability and molecular mass forms. J Endocrinol 1996;151:77-86.
14. 14 Dignass AU, Podolsky DK. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor β. Gastroenterology 1993;105:1323-32.
15. 15 Shing YW, Klagsbrun M. Purification and characterisation of a bovine colostrum-derived growth factor. Mol Endocrinol 1987;1:335-8.
16. 16 Shing YW, Klagsbrun M. Human and bovine milk contain different sets of growth factors. Endocrinology 1984;115: 273-82.
17. 17 Fries JF. NSAID gastropathy: the second most deadly rheumatic disease? Epidemiology and risk appraisal. J Rheumatol 1991;28(suppl):6-10.
18. 18 Wilholm BE, Myrhed M, Ekman E. Trends and patterns in adverse drug reactions to non-steroidal anti-inflammatory drugs reported in Sweden. In: Rainsfoird KD, Velo GP, eds. Side effects of anti-inflammatory drugs. Lancaster: MTP press, 1987:55-70.
19. 19 MacDonald TM, Morant SV, Robinson GC, et al. Association of upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs with continued exposure: cohort study. BMJ 1997;315:1333-7.
20. 20 Paulus HE. PDA Arthritis Advisory Committee Meeting: Serious gastrointestinal toxicity of non-steroidal anti-inflammatory drugs; drug containing renal and biliary stones; diclofenac and carpofen approved. Arthritis Rheum 1988;31:1450-1.
21. 21 Langman MJS, Morgan L, Worrall A. Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage. BMJ 1985;290: 347-9.
22. 22 Wojtulewski JA, Schattenkirchner M, Barcelo P, et al. A six month double blinded trial to compare the efficacy and safety of meloxicam 7.5 mg daily and naproxen 750 mg daily in patients with rheumatoid arthritis. Br J Rheumatol 1996;35(suppl 1):22-8.
23. 23 Distel M, Mueller C, Bluhmki E, et al. Safety of meloxicam - a global analysis of clinical trials. Br J Rheumatol 1996;35:68-77.
24. 24 Levi S, Shaw-Smith C. Non-steroidal anti-inflammatory drugs: how do they damage the gut? Br J Rheumatol 1994; 33:605-12.
25. 25 Playford RJ, Watanaba P, Woodman AC, et al. Effect of luminal growth factor preservation on intestinal growth. Lancet 1993;341:843-8.
26. 26 Chinery R, Playford RJ. Rapid communication: combined intestinal trefoil factor and epidermal growth factor is prophylatic against indomethacin-induced gastric damage in the rat. Clin Sci 1995;88:401-3.