Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip

Gene Expression Patterns

Volumn 11, Issue 5-6, 2011, Pages 349-359

  Machold, R ^a   Klein, C ^a,b   Fishell, G ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ABBOTT GMBH AND CO KG   (Germany)

Author keywords

Atoh1; Brainstem; Cerebellum; Gene expression screen; Genetic fate mapping; Granule cell precursors; Isthmus; Math1; Microarrays; Neurogenesis; Rhombic lip; Rhombomere 1

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ATOH 1; UNCLASSIFIED DRUG;

ARTICLE; BRAIN STEM; CELL CYCLE REGULATION; CELL FATE; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELL SURFACE; DOWNSTREAM PROCESSING; GENE EXPRESSION; GRANULE CELL; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; RHOMBENCEPHALIC ISTHMUS; RHOMBOMERE 1;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINEAGE; CEREBELLUM; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, TRANSGENIC; NEUROGENESIS; NEURONS;

EID: 79955942143     PISSN: 1567133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gep.2011.03.007     Document Type: Article

References (56)

1. Ackerman, S.L., Kozak, L.P., Przyborski, S.A., Rund, L.A., Boyer, B.B., Knowles, B.B., 1997. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein. Nature 386, 838-842. (Pubitemid 27181258)
2. Alder, J., Lee, K.J., Jessell, T.M., Hatten, M.E., 1999. Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells. Nat. Neurosci. 2, 535-540.
3. Aruga, J., Nagai, T., Tokuyama, T., Hayashizaki, Y., Okazaki, Y., Chapman, V.M., Mikoshiba, K., 1996. The mouse zic gene family homologues of the Drosophila pair-rule gene odd-paired. J. Biol. Chem. 271, 1043-1047.
4. Bae, S., Bessho, Y., Hojo, M., Kageyama, R., 2000. The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation. Development 127, 2933-2943. (Pubitemid 30487611)
5. Batista-Brito, R., Machold, R., Klein, C., Fishell, G., 2008. Gene expression in cortical interneuron precursors is prescient of their mature function. Cereb. Cortex 18, 2306-2317.
6. Ben-Arie, N., Bellen, H.J., Armstrong, D.L., McCall, A.E., Gordadze, P.R., Guo, Q., Matzuk, M.M., Zoghbi, H.Y., 1997. Math1 is essential for genesis of cerebellar granule neurons. Nature 390, 169-172. (Pubitemid 27507985)
7. Ben-Arie, N., Hassan, B.A., Bermingham, N.A., Malicki, D.M., Armstrong, D., Matzuk, M., Bellen, H.J., Zoghbi, H.Y., 2000. Functional conservation of atonal and Math1 in the CNS and PNS. Development 127, 1039-1048. (Pubitemid 30162650)
8. Brandenberger, R., Schmidt, A., Linton, J., Wang, D., Backus, C., Denda, S., Muller, U., Reichardt, L.F., 2001. Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha8beta1 in the embryonic kidney. J. Cell Biol. 154, 447-458. (Pubitemid 34286153)
9. Broccoli, V., Boncinelli, E., Wurst, W., 1999. The caudal limit of Otx2 expression positions the isthmic organizer. Nature 401, 164-168. (Pubitemid 29436319)
10. Bulfone, A., Menguzzato, E., Broccoli, V., Marchitiello, A., Gattuso, C., Mariani, M., Consalez, G.G., Martinez, S., Ballabio, A., Banfi, S., 2000. Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS. Hum. Mol. Genet. 9, 1443-1452.
11. Clotman, F., Jacquemin, P., Plumb-Rudewiez, N., Pierreux, C.E., Van der Smissen, P., Dietz, H.C., Courtoy, P.J., Rousseau, G.G., Lemaigre, F.P., 2005. Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. Genes Dev. 19, 1849-1854. (Pubitemid 41186985)
12. D'Arcangelo, G., Nakajima, K., Miyata, T., Ogawa, M., Mikoshiba, K., Curran, T., 1997. Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody. J. Neurosci. 17, 23-31. (Pubitemid 27008847)
13. De Smaele, E., Fragomeli, C., Ferretti, E., Pelloni, M., Po, A., Canettieri, G., Coni, S., Di Marcotullio, L., Greco, A., Moretti, M., Di Rocco, C., Pazzaglia, S., Maroder, M., Screpanti, Giannini, G., Gulino, A., 2008. An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma. Neoplasia 10, 89-98. (Pubitemid 351170716)
14. Dubuc, A.M., Northcott, P.A., Mack, S., Witt, H., Pfister, S., Taylor, M.D., 2010. The genetics of pediatric brain tumors. Curr. Neurol. Neurosci. Rep. 10, 215-223.
15. Engelkamp, D., Rashbass, P., Seawright, A., van Heyningen, V., 1999. Role of Pax6 in development of the cerebellar system. Development 126, 3585-3596. (Pubitemid 29419515)
16. Englund, C., Kowalczyk, T., Daza, R.A., Dagan, A., Lau, C., Rose, M.F., Hevner, R.F., 2006. Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J. Neurosci. 26, 9184-9195. (Pubitemid 44359845)
17. Farkas, L.M., Haffner, C., Giger, T., Khaitovich, P., Nowick, K., Birchmeier, C., Paabo, S., Huttner, W.B., 2008. Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron 60, 40-55.
18. Fernandez, C., Tatard, V.M., Bertrand, N., Dahmane, N., 2010. Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network. Dev. Neurosci. 32, 59-70.
19. Fink, A.J., Englund, C., Daza, R.A., Pham, D., Lau, C., Nivison, M., Kowalczyk, T., Hevner, R.F., 2006. Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J. Neurosci. 26, 3066-3076.
20. Gilthorpe, J.D., Papantoniou, E.K., Chedotal, A., Lumsden, A., Wingate, R.J., 2002. The migration of cerebellar rhombic lip derivatives. Development 129, 4719-4728. (Pubitemid 35277199)
21. Hevner, R.F., Hodge, R.D., Daza, R.A., Englund, C., 2006. Transcription factors in glutamatergic neurogenesis: conserved programs in neocortex, cerebellum, and adult hippocampus. Neurosci Res. 55, 223-233. (Pubitemid 43766416)
22. Houweling, A.C., Dildrop, R., Peters, T., Mummenhoff, J., Moorman, A.F., Ruther, U., Christoffels, V.M., 2001. Gene and cluster-specific expression of the Iroquois family members during mouse development. Mech. Dev. 107, 169-174.
23. Julian, E., Hallahan, A.R., Wainwright, B.J., 2010. RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer. Neural Dev. 5, 27.
24. Karam, S.D., Burrows, R.C., Logan, C., Koblar, S., Pasquale, E.B., Bothwell, M., 2000. Eph receptors and ephrins in the developing chick cerebellum: relationship to sagittal patterning and granule cell migration. J. Neurosci. 20, 6488-6500.
25. Kerjan, G., Dolan, J., Haumaitre, C., Schneider-Maunoury, S., Fujisawa, H., Mitchell, K.J., Chedotal, A., 2005. The transmembrane semaphorin Sema6A controls cerebellar granule cell migration. Nat. Neurosci. 8, 1516-1524.
26. Machold, R., Fishell, G., 2005. Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron 48, 17-24. (Pubitemid 41384162)
27. Machold, R.P., Kittell, D.J., Fishell, G.J., 2007. Antagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip. Neural Dev. 2, 5.
28. Morales, D., Hatten, M.E., 2006. Molecular markers of neuronal progenitors in the embryonic cerebellar anlage. J. Neurosci. 26, 12226-12236. (Pubitemid 44808389)
29. Moran-Rivard, L., Kagawa, T., Saueressig, H., Gross, M.K., Burrill, J., Goulding, M., 2001. Evx1 is a postmitotic determinant of v0 interneuron identity in the spinal cord. Neuron 29, 385-399. (Pubitemid 32206478)
30. Pan, N., Jahan, I., Lee, J.E., Fritzsch, B., 2009. Defects in the cerebella of conditional Neurod1 null mice correlate with effective Tg(Atoh1-cre) recombination and granule cell requirements for Neurod1 for differentiation. Cell Tissue Res. 337, 407-428.
31. Puelles, E., Annino, A., Tuorto, F., Usiello, A., Acampora, D., Czerny, T., Brodski, C., Ang, S.L., Wurst, W., Simeone, A., 2004. Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain. Development 131, 2037-2048. (Pubitemid 38702037)
32. Qin, L., Wine-Lee, L., Ahn, K.J., Crenshaw 3rd, E.B., 2006. Genetic analyses demonstrate that bone morphogenetic protein signaling is required for embryonic cerebellar development. J. Neurosci. 26, 1896-1905.
33. Renaud, J., Kerjan, G., Sumita, I., Zagar, Y., Georget, V., Kim, D., Fouquet, C., Suda, K., Sanbo, M., Suto, F., Ackerman, S.L., Mitchell, K.J., Fujisawa, H., Chedotal, A., 2008. Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells. Nat. Neurosci. 11, 440-449.
34. Rose, M.F., Ahmad, K.A., Thaller, C., Zoghbi, H.Y., 2009. Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1. Proc. Natl. Acad. Sci. USA 106, 22462-22467.
35. Sammeta, N., Hardin, D.L., McClintock, T.S., 2010. Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium. Mol Cell Neurosci. 45, 398-407.
36. Sasaki, S., Tabata, H., Tachikawa, K., Nakajima, K., 2008. The cortical subventricular zone-specific molecule Svet1 is part of the nuclear RNA coded by the putative netrin receptor gene Unc5d and is expressed in multipolar migrating cells. Mol Cell Neurosci. 38, 474-483.
37. Scheffer, D., Sage, C., Corey, D.P., Pingault, V., 2007. Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells. FEBS Lett. 581, 4651-4656.
38. Solecki, D.J., Liu, X.L., Tomoda, T., Fang, Y., Hatten, M.E., 2001. Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation. Neuron 31, 557-568. (Pubitemid 32835111)
39. Sousa, V.H., Miyoshi, G., Hjerling-Leffler, J., Karayannis, T., Fishell, G., 2009. Characterization of Nkx6-2-derived neocortical interneuron lineages. Cereb Cortex 19 (Suppl. 1), i1-i10.
40. Subramaniam, S., Strelau, J., Unsicker, K., 2008. GDNF prevents TGF-beta-induced damage of the plasma membrane in cerebellar granule neurons by suppressing activation of p38-MAPK via the phosphatidylinositol 3-kinase pathway. Cell Tissue Res. 331, 373-383.
41. Thomas, K.R., Capecchi, M.R., 1990. Targeted disruption of the murine int-1 protooncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346, 847-850.
42. Timmer, J.R., Wang, C., Niswander, L., 2002. BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors. Development 129, 2459-2472. (Pubitemid 34863852)
43. Tribioli, C., Robledo, R.F., Lufkin, T., 2002. The murine fork head gene Foxn2 is expressed in craniofacial, limb, CNS and somitic tissues during embryogenesis. Mech. Dev. 118, 161-163.
44. Vernes, S.C., Fisher, S.E., 2009. Unravelling neurogenetic networks implicated in developmental language disorders. Biochem. Soc. Trans. 37, 1263-1269.
45. Wang, V.Y., Rose, M.F., Zoghbi, H.Y., 2005. Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum. Neuron 48, 31-43. (Pubitemid 41384164)
46. Wang, W., Mullikin-Kilpatrick, D., Crandall, J.E., Gronostajski, R.M., Litwack, E.D., Kilpatrick, D.L., 2007. Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules. J. Neurosci. 27, 6115-6127. (Pubitemid 46890020)
47. Weidinger, G., Thorpe, C.J., Wuennenberg-Stapleton, K., Ngai, J., Moon, R.T., 2005. The Sp1-related transcription factors sp5 and sp5-like act downstream of Wnt/beta-catenin signaling in mesoderm and neuroectoderm patterning. Curr. Biol. 15, 489-500.
48. Whelan, H.T., Nelson, D.B., Strother, D., Przybylski, C., Figge, G., Mamandi, A., 1989. Medulloblastoma cell line secretes platelet-derived growth factor. Pediatr. Neurol. 5, 347-352.
49. Wine-Lee, L., Ahn, K.J., Richardson, R.D., Mishina, Y., Lyons, K.M., Crenshaw 3rd, E.B., 2004. Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development 131, 5393-5403. (Pubitemid 39562182)
50. Wingate, R.J., 2001. The rhombic lip and early cerebellar development. Curr. Opin. Neurobiol. 11, 82-88.
51. Wingate, R.J., Hatten, M.E., 1999. The role of the rhombic lip in avian cerebellum development. Development 126, 4395-4404.
52. Yun, J.S., Rust, J.M., Ishimaru, T., Diaz, E., 2007. A novel role of the Mad family member Mad3 in cerebellar granule neuron precursor proliferation. Mol. Cell Biol. 27, 8178-8189.
53. Zetterstrom, R.H., Solomin, L., Jansson, L., Hoffer, B.J., Olson, L., Perlmann, T., 1997. Dopamine neuron agenesis in Nurr1-deficient mice. Science 276, 248-250. (Pubitemid 27172681)
54. Zhao, Z., Lee, C.C., Jiralerspong, S., Juyal, R.C., Lu, F., Baldini, A., Greenberg, F., Caskey, C.T., Patel, P.I., 1995. The gene for a human microfibril-associated glycoprotein is commonly deleted in Smith-Magenis syndrome patients. Hum. Mol. Genet. 4, 589-597.
55. Zhou, J., Wang, C., Wang, Z., Dampier, W., Wu, K., Casimiro, M.C., Chepelev, I., Popov, V.M., Quong, A., Tozeren, A., Zhao, K., Lisanti, M.P., Pestell, R.G., 2010. Attenuation of Forkhead signaling by the retinal determination factor DACH1. Proc. Natl. Acad. Sci. USA 107, 6864-6869.
56. Zou, Y.R., Kottmann, A.H., Kuroda, M., Taniuchi, I., Littman, D.R., 1998. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393, 595-599. (Pubitemid 28319251)