Chronic ethanol consumption in rats produces opioid antinociceptive tolerance through inhibition of mu opioid receptor endocytosis

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  He, Li ^a   Whistler, Jennifer L ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BETA ENDORPHIN; ENKEPHALIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; G PROTEIN COUPLED RECEPTOR KINASE 2; MORPHINE SULFATE; MU OPIATE RECEPTOR; NARCOTIC ANALGESIC AGENT; ANALGESIC AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRINKING BEHAVIOR; DRUG TOLERANCE; ENDOCYTOSIS; LONG TERM EXPOSURE; MALE; NONHUMAN; PROTEIN PROTEIN INTERACTION; RAT; ANIMAL; CHRONIC DISEASE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

RATTUS;

ALCOHOL DRINKING; ANALGESICS; ANALGESICS, OPIOID; ANIMALS; BIOLOGICAL TRANSPORT; CHRONIC DISEASE; DRUG TOLERANCE; ENDOCYTOSIS; ETHANOL; GTP-BINDING PROTEINS; RATS; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION;

EID: 79955938802     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019372     Document Type: Article

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