The biochemical analysis of methadone modulation on morphine-induced tolerance and dependence in the rat brain

Pharmacology

Volumn 79, Issue 4, 2007, Pages 193-202

  He, Li ^a   Whistler, Jennifer L ^a  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

Author keywords

Adenylyl cyclase; Analgesia; GTP S binding; Methadone; Morphine dependence; Morphine tolerance; Opioid receptor endocytosis

Indexed keywords

ADENYLATE CYCLASE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FORSKOLIN DERIVATIVE; G PROTEIN COUPLED RECEPTOR; METHADONE; MORPHINE; MU OPIATE RECEPTOR; NALOXONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; CHEMICAL ANALYSIS; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVITY; MALE; MONOTHERAPY; MORPHINE ADDICTION; MORPHINE TOLERANCE; NEUROMODULATION; NONHUMAN; PARAMETER; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WITHDRAWAL SYNDROME;

ADENYLATE CYCLASE; ANALGESICS, OPIOID; ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; DRUG TOLERANCE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MALE; METHADONE; MORPHINE; MORPHINE DEPENDENCE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU;

EID: 34249774895     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000100893     Document Type: Article

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