Methadone Antinociception Is Dependent on Peripheral Opioid Receptors

Journal of Pain

Volumn 10, Issue 4, 2009, Pages 369-379

  He, Li ^a   Kim, Joseph ^a   Ou, Chrissi ^a   McFadden, Whitney ^a   van Rijn, Richard M ^a   Whistler, Jennifer L ^a  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

Author keywords

Antinociception; methadone; morphine; opioid receptor; periphery

Indexed keywords

17 METHYLNALOXONE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); METHADONE; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; OPIATE RECEPTOR; SULFUR 35;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; MALE; MOUSE; NONHUMAN; PAIN; PERIAQUEDUCTAL GRAY MATTER; RADIOASSAY; RAT; STEREOTAXIC SURGERY; TAIL FLICK TEST;

ANALGESICS, OPIOID; ANIMALS; DRUG ADMINISTRATION ROUTES; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; INJECTIONS, SUBCUTANEOUS; MALE; METHADONE; MICE; MORPHINE; NALOXONE; PAIN; PAIN MEASUREMENT; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; SPECIES SPECIFICITY;

EID: 62649167899     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2008.09.011     Document Type: Article

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