Polyethylenimine-mediated PUMA gene delivery to orthotopic oral cancer: Suppression of tumor growth through apoptosis induction in situ and prolonged survival

Head and Neck

Volumn 33, Issue 6, 2011, Pages 878-885

  Yeh, Cheng Chang ^a   Hsieh, Hsiao Ling ^b   Lee, Jihjong ^c   Jan, Yi Hua ^b   Lai, Tsung Ching ^b   Hong, Chi Yuan ^d   Hsiao, Michael ^b   Kuo, Mark Y P ^a,d  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

apoptosis; gene therapy; oral cancer; PEI; PUMA

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYETHYLENEIMINE; PUMA PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER SURVIVAL; ENZYME ACTIVATION; ENZYME RELEASE; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; MOUTH CANCER; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TUMOR GROWTH;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CYTOCHROMES C; DISEASE MODELS, ANIMAL; GENE THERAPY; GENETIC VECTORS; HUMANS; IN SITU NICK-END LABELING; KAPLAN-MEIER ESTIMATE; MICE; MICE, SCID; MOUTH NEOPLASMS; NEOPLASMS, EXPERIMENTAL; POLYETHYLENEIMINE; RANDOM ALLOCATION; SENSITIVITY AND SPECIFICITY; STATISTICS, NONPARAMETRIC; SURVIVAL RATE; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 79955927660     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.21555     Document Type: Article

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