NCAM1, TACR1 and NOS genes and temperament: A study on suicide attempters and controls

Neuropsychobiology

Volumn 64, Issue 1, 2011, Pages 32-37

  Giegling, Ina ^a   Calati, Raffaella ^b   Porcelli, Stefano ^b   Hartmann, Annette M ^a   Möller, Hans Jürgen ^a   De Ronchi, Diana ^b   Rujescu, Dan ^a   Serretti, Alessandro ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

NCAM1; NOS; TACR1; Temperament

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; NERVE CELL ADHESION MOLECULE; NERVE CELL ADHESION MOLECULE 1; NEURONAL NITRIC OXIDE SYNTHASE; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PERSONALITY; PRIORITY JOURNAL; REWARD; SUICIDE ATTEMPT; TEMPERAMENT; TEMPERAMENT AND CHARACTER INVENTORY;

ADULT; ANTIGENS, CD56; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE III; PERSONALITY; PERSONALITY ASSESSMENT; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, TACHYKININ; SUICIDE, ATTEMPTED; TEMPERAMENT;

EID: 79955927199     PISSN: 0302282X     EISSN: 14230224     Source Type: Journal    
DOI: 10.1159/000324993     Document Type: Article

References (27)

1. World Health Organization: Burden of Men-tal and Behavioural Disorders: Suicide. Ge-neva, WHO 2005.
2. Brezo J, Paris J, Turecki G: Personality traits as correlates of suicidal ideation, suicide at-tempts, and suicide completions: a system-atic review. Acta Psychiatrica Scandinavica 2006; 113:180-206. (Pubitemid 43340872)
3. Gau SS, Chen YY, Tsai FJ, Lee MB, Chiu YN, Soong WT, Hwu HG: Risk factors for suicide in Taiwanese college students. J Am Coll Health 2008; 57: 135-142.
4. Novakovic M, Ille T, Maric-Tiosavljevic D: Forms of parasuicide in young people in Bosnia. Psychiatr Danub 2006; 18: 39-47. (Pubitemid 44082080)
5. Allen MH, Chessick CA, Miklowitz DJ, Goldberg JF, Wisniewski SR, Miyahara S, Calabrese JR, Marangell L, Bauer MS, Thom-as MR, Bowden CL, Sachs GS: Contributors to suicidal ideation among bipolar patients with and without a history of suicide at-tempts. Suicide Life Threat Behav 2005; 35: 671-680. (Pubitemid 43161558)
6. Conrad R, Walz F, Geiser F, Imbierowicz K, Liedtke R, Wegener I: Temperament and character personality profile in relation to suicidal ideation and suicide attempts in ma-jor depressed patients. Psychiatry Res 2009; 170:212-217.
7. Calati R, Giegling I, Rujescu D, Hartmann AM, Moller HJ, De Ronchi D, Serretti A: Temperament and character of suicide at-tempters. J Psychiatr Res 2008; 42: 938-945.
8. Chapman AL, Derbidge CM, Cooney E, Hong PY, Linehan MM: Temperament as a prospective predictor of self-injury among patients with borderline personality disorder. J Pers Disord 2009; 23: 122-140.
9. Cloninger CR, Przybeck TR, Svrakic DM, Wetzel RD: The Temperament and Charac-ter Inventory (TCI): A Guide to Its Develop-ment and Use. St. Louis, Center for Psycho-biology of Personality Washington University, 1994.
10. Ebstein RP: The molecular genetic architec-ture of human personality: beyond self-re-port questionnaires. Mol Psychiatry 2006; 11: 427-445.
11. Noblett KL, Coccaro EF: Molecular genetics of personality. Curr Psychiatry Rep 2005; 7: 73-80. (Pubitemid 40485482)
12. Savitz JB, Ramesar RS: Genetic variants im-plicated in personality: a review of the more promising candidates. Am J Med Genet 2004; 23: 23.
13. Serretti A, Calati R, Ferrari B, De Ronchi D: Personality and genetics. Curr Psychiatry Rev 2007; 3:147-159. (Pubitemid 46773913)
14. Van Gestel S, Van Broeckhoven C: Genetics of personality: are we making progress? Mol Psychiatry 2003; 8:840-852. (Pubitemid 37346539)
15. Rujescu D, Thalmeier A, Moeller HJ, Bronisch T, Giegling I: Molecular genetic findings in suicidal behavior: What is be-yond the serotonergic system? Arch Suicide Res 2007; 11:17-40.
16. Rujescu D, Giegling I, Mandelli L, Schneider B, Hartmann AM, Schnabel A, Maurer K, Moller HJ, Serretti A: NOS-I and-III gene variants are differentially associated with facets of suicidal behavior and aggression-related traits. Am J Med Genet B NeuroPsychiatr Genet 2008; 147:42-48.
17. Giegling I, Rujescu D, Mandel li L, Schneider B, Hartmann AM, Schnabel A, Maurer K, De Ronchi D, Moller HJ, Serretti A: Tachykinin receptor 1 variants associated with aggres-sion in suicidal behavior. Am J Med Genet B Neuropsychiatr Genet 2007; 144B:757-761. (Pubitemid 47417204)
18. Giegling I, Chiesa A, Mandelli L, Gibiino S, Hartmann A, Möller HJ, Schneider B, Schna-bel A, Maurer K, De Ronchi D, Rujescu D, Serretti A: Influence of neuronal cell adhe-sion molecule (NCAM1) variants on suicidal behaviour and correlated traits. Psychiatry Res 2010; 179:222-225.
19. Serretti A, Calati R, Giegling I, Hartmann AM, Moller HJ, Colombo C, Rujescu D: 5-HT(2A) SNPs and the temperament and character inventory. Prog Neuropsychophar-macol Biol Psychiatry 2007; 31:1275-1281. (Pubitemid 47081316)
20. First MB, Spitzer RL, Gibbon M, Williams BW, Benjamin L: Structured Clinical Inter-view for DSM-IV Axis II Personality disorders (SCID-II). New York, New York State Psychiatric Institute, 1990.
21. First MB, Spitzer RL, Gibbon M, Williams JB: Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0): New York, New York State Psychiatric Institute, 1995.
22. Giegling I, Hartmann AM, Moller HJ, Ru-jescu D: Anger-and aggression-related traits are associated with polymorphisms in the 5-HT-2A gene. J Affect Dis 2006; 96: 75-81. (Pubitemid 44548047)
23. Rujescu D, Giegling I, Gietl A, Hartmann AM, Moller HJ: A functional single nucleo-tide polymorphism (V158M) in the COMT gene is associated with aggressive personal-ity traits. Biol Psychiatry 2003; 54: 34-39. (Pubitemid 36776721)
24. Barrett JC, Fry B, Maller J, Daly MJ: Haplo-view: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265. (Pubitemid 40202029)
25. Laas K, Reif A, Herterich S, Eensoo D, Lesch KP, Harro J: The effect of a functional NOS1 promoter polymorphism on impulsivity is moderated by platelet M AO activity. Psychopharmacology (Berl) 2010; 209:255-261.
26. Reif A, Jacob CP, Rujescu D, Herterich S, Lang S, Gutknecht L, Baehne CG, Strobel A, Freitag CM, Giegling I, Romanos M, Hart-mann A, Rosler M, Renner TJ, Fallgatter AJ, Retz W, Ehlis AC, Lesch KP: Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans. Arch Gen Psychiatry 2009; 66:41-50.
27. Retz W, Reif A, Freitag CM, Retz-Junginger P, Rosler M: Association of a functional vari-ant of neuronal nitric oxide synthase gene with self-reported impulsiveness, venture-someness and empathy in male offenders. J Neural Transm 2010; 117:321-324.