-
1
-
-
0022371467
-
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
-
M Boshart F Weber G Jahn K Dorsch-Häsler B Fleckenstein W Schaffner 1985 A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus Cell 41 521 530 10.1016/S0092-8674(85)80025-8 1:CAS:528:DyaL2MXks1GrtLw%3D (Pubitemid 16219422)
-
(1985)
Cell
, vol.41
, Issue.2
, pp. 521-530
-
-
Boshart, M.1
Weber, F.2
Jahn, G.3
-
2
-
-
0035313152
-
Therapeutic antibody expression technology
-
DOI 10.1016/S0958-1669(00)00198-1
-
HE Chadd SM Chamow 2001 Therapeutic antibody expression technology Current Opinion in Biotechnology 12 188 194 10.1016/S0958-1669(00)00198-1 1:CAS:528:DC%2BD3MXjt1Olu7c%3D (Pubitemid 32247407)
-
(2001)
Current Opinion in Biotechnology
, vol.12
, Issue.2
, pp. 188-194
-
-
Chadd, H.E.1
Chamow, S.M.2
-
3
-
-
33747370959
-
Antibody production
-
DOI 10.1016/j.addr.2005.12.006, PII S0169409X06000883
-
JR Birch AJ Racher 2006 Antibody production Advanced Drug Delivery Reviews 58 671 685 10.1016/j.addr.2005.12.006 1:CAS:528:DC%2BD28XoslKrsb4%3D (Pubitemid 44247226)
-
(2006)
Advanced Drug Delivery Reviews
, vol.58
, Issue.5-6
, pp. 671-685
-
-
Birch, J.R.1
Racher, A.J.2
-
5
-
-
46349085153
-
Post-translational modifications of recombinant proteins: Significance for biopharmaceuticals
-
10.1007/s12033-008-9049-4 1:CAS:528:DC%2BD1cXmtFegsLo%3D
-
N Jenkins L Murphy R Tyther 2008 Post-translational modifications of recombinant proteins: Significance for biopharmaceuticals Molecular Biotechnology 39 113 118 10.1007/s12033-008-9049-4 1:CAS:528: DC%2BD1cXmtFegsLo%3D
-
(2008)
Molecular Biotechnology
, vol.39
, pp. 113-118
-
-
Jenkins, N.1
Murphy, L.2
Tyther, R.3
-
6
-
-
13544259722
-
On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells
-
DOI 10.1021/bp049780w
-
S Schlatter SH Stansfield DM Dinnis AJ Racher JR Birch DC James 2005 On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells Biotechnology Progress 21 122 133 10.1021/bp049780w 1:CAS:528:DC%2BD2cXpslent7o%3D (Pubitemid 40218480)
-
(2005)
Biotechnology Progress
, vol.21
, Issue.1
, pp. 122-133
-
-
Schlatter, S.1
Stansfield, S.H.2
Dinnis, D.M.3
Racher, A.J.4
Birch, J.R.5
James, D.C.6
-
7
-
-
0036135719
-
Transcriptional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position
-
DOI 10.1128/MCB.22.2.469-479.2002
-
SK Eszterhas EE Bouhassira DI Martin S Fiering 2002 Transcriptional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position Molecular and Cellular Biology 22 469 479 10.1128/MCB.22.2.469-479.2002 1:CAS:528:DC%2BD38XhvVersA%3D%3D (Pubitemid 34027492)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.2
, pp. 469-479
-
-
Eszterhas, S.K.1
Bouhassira, E.E.2
Martin, D.I.K.3
Fiering, S.4
-
8
-
-
70350495670
-
High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169
-
10.1099/vir.0.013250-0 1:CAS:528:DC%2BD1MXht1Ghu7bI
-
AJ Bradley NS Lurain P Ghazal U Trivedi C Cunningham K Baluchova D Gatherer GW Wilkinson DJ Dargan AJ Davison 2009 High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169 Journal of General Virology 90 2375 2380 10.1099/vir.0.013250-0 1:CAS:528: DC%2BD1MXht1Ghu7bI
-
(2009)
Journal of General Virology
, vol.90
, pp. 2375-2380
-
-
Bradley, A.J.1
Lurain, N.S.2
Ghazal, P.3
Trivedi, U.4
Cunningham, C.5
Baluchova, K.6
Gatherer, D.7
Wilkinson, G.W.8
Dargan, D.J.9
Davison, A.J.10
-
9
-
-
0025866787
-
Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells
-
BS Chapman RM Thayer KA Vincent NL Haigwood 1991 Effect of intron A from human cytomegalovirus (Towne) immediate-early gene on heterologous expression in mammalian cells Nucleic Acids Research 19 3979 3986 10.1093/nar/19.14.3979 1:CAS:528:DyaK3MXmtVShsbo%3D (Pubitemid 21912770)
-
(1991)
Nucleic Acids Research
, vol.19
, Issue.14
, pp. 3979-3986
-
-
Chapman, B.S.1
Thayer, R.M.2
Vincent, K.A.3
Haigwood, N.L.4
-
10
-
-
0025847620
-
Recombinase-mediated gene activation and site-specific integration in mammalian cells
-
S O'Gorman DT Fox GM Wahl 1991 Recombinase-mediated gene activation and site-specific integration in mammalian cells Science 251 1351 1355 10.1126/science.1900642 (Pubitemid 21916917)
-
(1991)
Science
, vol.251
, Issue.4999
, pp. 1351-1355
-
-
O'Gorman, S.1
Fox, D.T.2
Wahl, G.M.3
-
11
-
-
33744498904
-
Production of target-specific recombinant human polyclonal antibodies in mammalian cells
-
DOI 10.1002/bit.20865
-
FC Wiberg SK Rasmussen TP Frandsen LK Rasmussen K Tengbjerg VW Coljee J Sharon CY Yang S Bregenholt LS Nielsen JS Haurum AB Tolstrup 2006 Production of target-specific recombinant human polyclonal antibodies in mammalian cells Biotechnology and Bioengineering 94 396 405 10.1002/bit.20865 1:CAS:528:DC%2BD28XkvFWju7g%3D (Pubitemid 43799538)
-
(2006)
Biotechnology and Bioengineering
, vol.94
, Issue.2
, pp. 396-405
-
-
Wiberg, F.C.1
Rasmussen, S.K.2
Frandsen, T.P.3
Rasmussen, L.K.4
Tengbjerg, K.5
Coljee, V.W.6
Sharon, J.7
Yang, C.-Y.8
Bregenholt, S.9
Nielsen, L.S.10
Haurum, J.S.11
Tolstrup, A.B.12
-
13
-
-
0242317675
-
Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis
-
10.1093/nar/gng073
-
SN Peirson JN Butler RG Foster 2003 Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis Nucleic Acids Research 31 e73 10.1093/nar/gng073
-
(2003)
Nucleic Acids Research
, vol.31
, pp. 73
-
-
Peirson, S.N.1
Butler, J.N.2
Foster, R.G.3
-
15
-
-
0033546210
-
The organization of replication and transcription
-
DOI 10.1126/science.284.5421.1790
-
PR Cook 1999 The organization of replication and transcription Science 284 1790 1795 10.1126/science.284.5421.1790 1:CAS:528:DyaK1MXjvFSru7g%3D (Pubitemid 29291422)
-
(1999)
Science
, vol.284
, Issue.5421
, pp. 1790-1795
-
-
Cook, P.R.1
-
16
-
-
70450222694
-
A model for all genomes: The role of transcription factories
-
10.1016/j.jmb.2009.10.031 1:CAS:528:DC%2BD1MXhsV2nu7fI
-
PR Cook 2010 A model for all genomes: the role of transcription factories Journal of Molecular Biology 395 1 10 10.1016/j.jmb.2009.10.031 1:CAS:528:DC%2BD1MXhsV2nu7fI
-
(2010)
Journal of Molecular Biology
, vol.395
, pp. 1-10
-
-
Cook, P.R.1
-
17
-
-
0029075822
-
Co-regulation of two gene activities by tetracycline via a bidirectional promoter
-
10.1093/nar/23.17.3605 1:CAS:528:DyaK2MXotlKgtr4%3D
-
U Baron S Freundlieb M Gossen H Bujard 1995 Co-regulation of two gene activities by tetracycline via a bidirectional promoter Nucleic Acids Research 23 3605 3606 10.1093/nar/23.17.3605 1:CAS:528:DyaK2MXotlKgtr4%3D
-
(1995)
Nucleic Acids Research
, vol.23
, pp. 3605-3606
-
-
Baron, U.1
Freundlieb, S.2
Gossen, M.3
Bujard, H.4
-
18
-
-
15244351083
-
Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
-
DOI 10.1038/nbt1049
-
M Amendola MA Venneri A Biffi E Vigna L Naldini 2005 Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters Nature Biotechnology 23 108 116 10.1038/nbt1049 1:CAS:528:DC%2BD2MXhsFGmsg%3D%3D (Pubitemid 41724633)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.1
, pp. 108-116
-
-
Amendola, M.1
Venneri, M.A.2
Biffi, A.3
Vigna, E.4
Naldini, L.5
-
19
-
-
33845906594
-
A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies
-
DOI 10.1016/j.jim.2006.10.010, PII S0022175906003036
-
J Li C Menzel D Meier C Zhang S Dübel T Jostock 2007 A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies Journal of Immunological Methods 318 113 124 10.1016/j.jim.2006. 10.010 1:CAS:528:DC%2BD2sXisVKitg%3D%3D (Pubitemid 46026813)
-
(2007)
Journal of Immunological Methods
, vol.318
, Issue.1-2
, pp. 113-124
-
-
Li, J.1
Menzel, C.2
Meier, D.3
Zhang, C.4
Dubel, S.5
Jostock, T.6
-
20
-
-
0024323801
-
Poly(A), poly(A) binding protein and the regulation of mRNA stability
-
P Bernstein J Ross 1989 Poly(A), poly(A) binding protein and the regulation of mRNA stability Trends in Biochemical Sciences 14 373 377 10.1016/0968-0004(89)90011-X 1:CAS:528:DyaL1MXmt1Ohtbo%3D (Pubitemid 19212998)
-
(1989)
Trends in Biochemical Sciences
, vol.14
, Issue.9
, pp. 373-377
-
-
Bernstein, P.1
Ross, J.2
-
21
-
-
0025269031
-
Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA
-
10.1093/nar/18.4.937 1:CAS:528:DyaK3cXhslent7Y%3D
-
MT Huang CM Gorman 1990 Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA Nucleic Acids Research 18 937 947 10.1093/nar/18.4.937 1:CAS:528:DyaK3cXhslent7Y%3D
-
(1990)
Nucleic Acids Research
, vol.18
, pp. 937-947
-
-
Huang, M.T.1
Gorman, C.M.2
-
22
-
-
0032853356
-
A strong negative transcriptional regulatory region between the human cytomegalovirus UL127 gene and the major immediate-early enhancer
-
CA Lundquist JL Meier MF Stinski 1999 A strong negative transcriptional regulatory region between the human cytomegalovirus UL127 gene and the major immediate-early enhancer Journal of Virology 73 9039 9052 1:CAS:528: DyaK1MXmslGrt7o%3D (Pubitemid 29487057)
-
(1999)
Journal of Virology
, vol.73
, Issue.11
, pp. 9039-9052
-
-
Lundquist, C.A.1
Meier, J.L.2
Stinski, M.F.3
-
23
-
-
0033999578
-
Identification of a boundary domain adjacent to the potent human cytomegalovirus enhancer that represses transcription of the divergent UL127 promoter?
-
DOI 10.1128/JVI.74.6.2826-2839.2000
-
A Angulo D Kerry H Huang EM Borst A Razinsky J Wu U Hobom M Messerle P Ghazal 2000 Identification of a boundary domain adjacent to the potent human cytomegalovirus enhancer that represses transcription of the divergent UL127 promoter Journal of Virology 74 2826 2839 10.1128/JVI.74.6.2826-2839.2000 1:CAS:528:DC%2BD3cXhsFChsr8%3D (Pubitemid 30117594)
-
(2000)
Journal of Virology
, vol.74
, Issue.6
, pp. 2826-2839
-
-
Angulo, A.1
Kerry, D.2
Huang, H.3
Borst, E.-M.4
Razinsky, A.5
Wu, J.6
Hobom, U.7
Messerle, M.8
Ghazal, P.9
-
24
-
-
8344271026
-
Production of recombinant protein therapeutics in cultivated mammalian cells
-
DOI 10.1038/nbt1026
-
FM Wurm 2004 Production of recombinant protein therapeutics in cultivated mammalian cells Nature Biotechnology 22 1393 1398 10.1038/nbt1026 1:CAS:528:DC%2BD2cXptlSls7k%3D (Pubitemid 39482858)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.11
, pp. 1393-1398
-
-
Wurm, F.M.1
-
25
-
-
0034751164
-
Position effects are influenced by the orientation of a transgene with respect to flanking chromatin
-
10.1128/MCB.21.1.298-309.2001 1:CAS:528:DC%2BD3MXptVSh
-
YQ Feng MC Lorincz S Fiering JM Greally EE Bouhassira 2001 Position effects are influenced by the orientation of a transgene with respect to flanking chromatin Molecular and Cellular Biology 21 298 309 10.1128/MCB.21.1.298-309.2001 1:CAS:528:DC%2BD3MXptVSh
-
(2001)
Molecular and Cellular Biology
, vol.21
, pp. 298-309
-
-
Feng, Y.Q.1
Lorincz, M.C.2
Fiering, S.3
Greally, J.M.4
Bouhassira, E.E.5
-
26
-
-
0027465601
-
Local domains of supercoiling activate a eukaryotic promoter in vivo
-
DOI 10.1038/361746a0
-
M Dunaway EA Ostrander 1993 Local domains of supercoiling activate a eukaryotic promoter in vivo Nature 361 746 748 10.1038/361746a0 1:CAS:528:DyaK3sXhvVGjs7c%3D (Pubitemid 23070486)
-
(1993)
Nature
, vol.361
, Issue.6414
, pp. 746-748
-
-
Dunaway, M.1
Ostrander, E.A.2
-
27
-
-
0023433855
-
Supercoiling of the DNA template during transcription
-
10.1073/pnas.84.20.7024 1:CAS:528:DyaL1cXhtVyhsLc%3D
-
LF Liu JC Wang 1987 Supercoiling of the DNA template during transcription Proceedings of the National Academy of Sciences USA 84 7024 7027 10.1073/pnas.84.20.7024 1:CAS:528:DyaL1cXhtVyhsLc%3D
-
(1987)
Proceedings of the National Academy of Sciences USA
, vol.84
, pp. 7024-7027
-
-
Liu, L.F.1
Wang, J.C.2
-
28
-
-
41949083130
-
Altered histone H1 stoichiometry and an absence of nucleosome positioning on transfected DNA
-
10.1074/jbc.M709121200 1:CAS:528:DC%2BD1cXhvFelurg%3D
-
PB Hebbar TK Archer 2008 Altered histone H1 stoichiometry and an absence of nucleosome positioning on transfected DNA Journal of Biological Chemistry 283 4595 4601 10.1074/jbc.M709121200 1:CAS:528:DC%2BD1cXhvFelurg%3D
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 4595-4601
-
-
Hebbar, P.B.1
Archer, T.K.2
-
29
-
-
33845925860
-
The IE2 promoter/enhancer region from mouse CMV provides high levels of therapeutic protein expression in mammalian cells
-
DOI 10.1002/bit.21172
-
P Chatellard R Pankiewicz E Meier L Durrer C Sauvage MO Imhof 2007 The IE2 promoter/enhancer region from mouse CMV provides high levels of therapeutic protein expression in mammalian cells Biotechnology and Bioengineering 96 106 117 10.1002/bit.21172 1:CAS:528:DC%2BD2sXjsV2ltg%3D%3D (Pubitemid 46036165)
-
(2007)
Biotechnology and Bioengineering
, vol.96
, Issue.1
, pp. 106-117
-
-
Chatellard, P.1
Pankiewicz, R.2
Meier, E.3
Durrer, L.4
Sauvage, C.5
Imhof, M.O.6
-
30
-
-
0037188910
-
Bidirectional gene organization: A common architectural feature of the human genome
-
DOI 10.1016/S0092-8674(02)00758-4
-
N Adachi MR Lieber 2002 Bidirectional gene organization: A common architectural feature of the human genome Cell 109 807 809 10.1016/S0092- 8674(02)00758-4 1:CAS:528:DC%2BD38Xlt1eiurs%3D (Pubitemid 34785996)
-
(2002)
Cell
, vol.109
, Issue.7
, pp. 807-809
-
-
Adachi, N.1
Lieber, M.R.2
-
32
-
-
66349114167
-
Cross-species mapping of bidirectional promoters enables prediction of unannotated 5' UTRs and identification of species-specific transcripts
-
10.1186/1471-2164-10-189
-
H Piontkivska MQ Yang DM Larkin HA Lewin J Reecy L Elnitski 2009 Cross-species mapping of bidirectional promoters enables prediction of unannotated 5' UTRs and identification of species-specific transcripts BMC Genomics 10 189 10.1186/1471-2164-10-189
-
(2009)
BMC Genomics
, vol.10
, pp. 189
-
-
Piontkivska, H.1
Yang, M.Q.2
Larkin, D.M.3
Lewin, H.A.4
Reecy, J.5
Elnitski, L.6
-
33
-
-
0019841737
-
A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs
-
J de Villiers W Schaffner 1981 A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs Nucleic Acids Research 9 6251 6264 10.1093/nar/9.23.6251 (Pubitemid 12152281)
-
(1981)
Nucleic Acids Research
, vol.9
, Issue.23
, pp. 6251-6264
-
-
De Villiers, J.1
Schaffner, W.2
-
35
-
-
35548970476
-
Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent
-
10.1371/journal.pone.0000004
-
D Strathdee H Ibbotson SG Grant 2006 Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent PLoS One 1 1 9 10.1371/journal.pone.0000004
-
(2006)
PLoS One
, vol.1
, pp. 1-9
-
-
Strathdee, D.1
Ibbotson, H.2
Grant, S.G.3
-
36
-
-
41349098812
-
Effects of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers
-
DOI 10.1186/1472-6750-8-23
-
CY Hsu H Uludaǧ 2008 Effects of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers BMC Biotechnology 8 23 10.1186/1472-6750-8-23 (Pubitemid 351448058)
-
(2008)
BMC Biotechnology
, vol.8
, pp. 23
-
-
Hsu, C.1
Uludag, H.2
|