Effects of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers

BMC Biotechnology

Volumn 8, Issue , 2008, Pages 23-

  Hsu, Charlie ^a   Uludaǧ, Hasan ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CELLS; DNA; MOLECULES; TOPOLOGY;

BONE MARROW STROMAL CELLS; INTRACELLULAR DELIVERY; POLYETHYLENEIMINE;

GENETIC ENGINEERING;

CIRCULAR DNA; ENHANCED GREEN FLUORESCENT PROTEIN; LIPOFECTAMINE; PALMITIC ACID; PLASMID DNA; POLYETHYLENEIMINE; POLYLYSINE; POLYMER;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BONE MARROW; COMPLEX FORMATION; CONTROLLED STUDY; CULTURE MEDIUM; DISSOCIATION; GENE CASSETTE; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; MORPHOLOGY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; POLYMERASE CHAIN REACTION; RAT; REPORTER GENE; STROMA CELL; TRANSGENE;

ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; DNA; DRUG CARRIERS; FEMALE; GENETIC VECTORS; NUCLEIC ACID CONFORMATION; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION; VIRUSES;

RATTUS;

EID: 41349098812     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-8-23     Document Type: Article

References (32)

1. Park TG Jeong JH Kim SW Current status of polymeric gene delivery systems Adv Drug Deliv Rev 2006, 58(4):467-486 10.1016/ j.addr.2006.03.007 16781003
2. Tiera MJ Winnik FOM Fernandes JC Synthetic and natural polycations for gene therapy: State of the art and new perspectives Curr Gene Ther 2006, 6(1):59-71 10.2174/156652306775515510 16475946
3. Anada T Karinaga R Koumoto K Mizu M Nagasaki T Kato Y Taira K Shinkai S Sakurai K Linear double-stranded DNA that mimics an infective tail of virus genome to enhance transfection J Control Release 2005, 108(2-3):529-539 10.1016/j.jconrel.2005.08.019 16219384
4. Chen ZY Yant SR He CY Meuse L Shen S Kay MA Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver Mol Ther 2001, 3(3):403-410 10.1006/mthe.2001.0278 11273783
5. Cherng JY Schuurmans-Nieuwenbroek NM Jiskoot W Talsma H Zuidam NJ Hennink WE Crommelin DJ Effect of DNA topology on the transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid complexes J Control Release 1999, 60(2-3):343-353 10.1016/ S0168-3659(99)00089-9 10425339
6. Kamiya H Yamazaki J Harashima H Size and topology of exogenous DNA as determinant factors of transgene transcription in mammalian cells Gene Ther 2002, 9(22):1500-1507 10.1038/sj.gt.3301831 12407422
7. Schakowski F Gorschlüter M Junghans C Schroff M Buttgereit P Ziske C Schöttker B König-Merediz SA Sauerbruch T Wittig B Schmidt-Wolf IG A novel minimal-size vector (MIDGE) improves transgene expression in colon carcinoma cells and avoids transfection of undesired DNA Mol Ther 2001, 3(5 Pt 1):793-800 10.1006/mthe.2001.0322 11356084
8. van der Aa MA Koning GA d'Oliveira C Oosting RS Wilschut KJ Hennink WE Crommelin DJ An NLS peptide covalently linked to linear DNA does not enhance transfection efficiency of cationic polymer based gene delivery systems J Gene Med 2005, 7(2):208-217 10.1002/jgm.643 15508141
9. Robertson RM Laib S Smith DE Diffusion of isolated DNA molecules: dependence on length and topology Proc Natl Acad Sci USA 2006, 103(19):7310-7314 1450111 16648255 10.1073/pnas.0601903103
10. Incani V Tunis E Clements BA Olson C Kucharski C Somayaji V Lavasanifar A Uludag H Palmitic acid substitution on cationic polymers for effective delivery of plasmid DNA to bone marrow stromal cells J Biomed Mat Res 2007, 81(2):493-504 10.1002/jbm.a.31249
11. Rudolph C Muller RH Rosenecker J Jet nebulization of PEI/DNA polyplexes: physical stability and in vitro gene delivery efficiency J Gene Med 2002, 4(1):66-74 10.1002/jgm.225 11828389
12. Varkey M Kucharski C Haque T Sebald W Uludag H In vitro osteogenic response of rat bone marrow cells to bFGF and BMP-2 treatments Clin Orthop Rel Res 2006, 443(2):113-123
13. Cherng JY van de Wetering P Talsma H Crommelin DJ Hennink WE Effect of size and serum proteins on transfection efficiency of poly ((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles Pharm Res 1996, 13(7):1038-1042 10.1023/A:1016054623543 8842041
14. Escriou V Carriere M Scherman D Wils P NLS bioconjugates for targeting therapeutic genes to the nucleus Adv Drug Deliv Rev 2003, 55(2):295-306 10.1016/S0169-409X(02)00184-9 12564982
15. Deniss IS Morgan AR Studies on the mechanism of DNA cleavage by ethidium Nucleic Acids Res 1976, 3(2):315-323 342903 1257050
16. Krishnamurthy G Polte T Rooney T Hogan ME A photochemical method to map ethidium bromide binding sites on DNA: Application to a bent DNA fragment Biochemistry 1990, 29(4):981-988 10.1021/bi00456a021 2340289
17. Kawaura C Noguchi A Furuno T Nakanishi M Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative FEBS 1998, 421(1):69-72 10.1016/ S0014-5793(97)01532-9
18. Kabanov AV Kabanov VA DNA complexes with polycations for the delivery of genetic material into cells Bioconjug Chem 1995, 6(1):7-20 10.1021/ bc00031a002 7711106
19. Arigita C Zuidam NJ Crommelin DJ Hennink WE Association and dissociation characteristics of polymer/DNA complexes used for gene delivery Pharm Res 1999, 16(10):1534-1541 10.1023/A:1015096302720 10554094
20. Schaffer DV Fidelman NA Dan N Lauffenburger DA Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery Biotechnol Bioeng 2000, 67(5):598-606 10.1002/ (SICI)1097-0290(20000305)67:5<598::AID-BIT10>3.0.CO;2-G 10649234
21. Hawley P Gibson I Interaction of oligodeoxynucleotides with mammalian cells Antisense Nucleic Acid Drug Dev 1996, 6(3):185-195 8915503
22. Mislick KA Baldeschwieler JD Evidence for the role of proteoglycans in cation-mediated gene transfer Proc Natl Acad Sci 1996, 93(22):12349-12354 37994 8901584 10.1073/pnas.93.22.12349
23. Ruponen M Ronkko S Honkakoski P Pelkonen J Tammi M Urtti A Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes J Biol Chem 2001, 276(36):33875-33880 10.1074/jbc.M011553200 11390375
24. Yang JP Huang L Time-dependent maturation of cationic liposome-DNA complex for serum resistance Gene Ther 1998, 5(3):380-387 10.1038/ sj.gt.3300596 9614558
25. Rejman J Conese M Hoekstra D Gene transfer by means of lipo- and polyplexes: Role of clathrin and caveolae-mediated endocytosis J Liposome Res 2006, 16(3):237-247 10.1080/08982100600848819 16952878
26. Medberry P Dennis S Van Hecke T DeLong RK Comparative heterogeneity, surface, binding, and activity analyses Biochem Biophys Res Commun 2004, 319(2):426-432 10.1016/j.bbrc.2004.04.188 15178424
27. Rosenecker J Naundorf S Gersting SW Hauck RW Gessner A Nicklaus P Muller RH Rudolph C Interaction of bronchoalveolar lavage fluid with polyplexes and lipoplexes: Analysing the role of proteins and glycoproteins J Gene Med 2003, 5(1):49-60 10.1002/jgm.291 12516051
28. Farrell L-L Hu W Pepin J Kucharski C Lin X Xu Z Uludag H A comparison of the effectiveness of cationic polymers poly-L-lysine (PLL) and polyethyleneimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells Eur J Pharmaceut Biopharmaceut 2007, 65(3):388-397 10.1016/j.ejpb.2006.11.026
29. Vitiello L Chonn A Wasserman JD Duff C Worton RG Condensation of plasmid DNA with polylysine improves liposome-mediated gene transfer into established and primary muscle cells Gene Ther 1996, 3(5):396-404 9156800
30. Escriou V Ciolina C Lacroix F Byk G Scherman D Wils P Cationic lipid-mediated gene transfer: Effect of serum on cellular uptake and intracellular fate of lipopolyamine/DNA complexes Biochim Biophys Acta 1998, 1368(2):276-288 10.1016/S0005-2736(97)00194-6 9459605
31. Sakurai F Inoue R Nishino Y Okuda A Matsumoto O Taga T Yamashita F Takakura Y Hashida M Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular trafficking of plasmid DNA/cationic liposome complexes and subsequent gene expression J Control Release 2000, 66(2-3):255-269 10.1016/ S0168-3659(99)00280-1 10742585
32. Remaut K Saunders NN Fajazpour F Demeester J De Smedt SC Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes J Control Release 2006, 115:335-343 10.1016/ j.jconrel.2006.08.009 17010468