Activation of KCNQ2/3 potassium channels by novel pyrazolo[1,5-a]pyrimidin- 7(4H)-one derivatives

Pharmacology

Volumn 87, Issue 5-6, 2011, Pages 297-310

  Jia, Caixia ^a   Qi, Jinlong ^a   Zhang, Fan ^a   Mi, Yi ^a   Zhang, Xuan ^a   Chen, Xingjuan ^a   Liu, Li ^a   Du, Xiaona ^a   Zhang, Hailin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Activation; KCNQ; M currents; Opener; Potassium channels

Indexed keywords

CHLOROMETHYL; METHYL GROUP; NAPHTHALENE; PHENYL GROUP; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ3; PYRAZOLE DERIVATIVE; PYRAZOLO[1,5 A]PYRIMIDIN 7(4H) ONE DERIVATIVE; QO 26; QO 28; QO 40; QO 41; RETIGABINE; TRIFLUOROMETHYL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; HYPERPOLARIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; STRUCTURE ACTIVITY RELATION;

ACTION POTENTIALS; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; KCNQ2 POTASSIUM CHANNEL; KCNQ3 POTASSIUM CHANNEL; NEURONS; PYRAZOLES; PYRIMIDINES; PYRIMIDINONES; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 79955881045     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000327384     Document Type: Article

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