Disruption of the epilepsy KCNQ2 gene results in neural hyperexcitability

Journal of Neurochemistry

Volumn 75, Issue 1, 2000, Pages 28-33

  Watanabe, Hirotaka ^a   Nagata, Eiichiro ^b   Kosakai, Arifumi ^b   Nakamura, Motonao ^a   Yokoyama, Masahiro ^a   Tanaka, Kortaro ^b   Sasai, Hitoshi ^a,c  

^a JT Ctrl Pharmaceutical Res Inst   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c JAPAN TOBACCO INC   (Japan)

Author keywords

Benign familial neonatal convulsion; Epilepsy; KCNQ2; Knockout mouse; M channel

Indexed keywords

PENTETRAZOLE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPILEPSY; FEMALE; GENE DISRUPTION; GENE EXPRESSION; GENE TARGETING; GENOTYPE; HETEROZYGOSITY; KNOCKOUT MOUSE; MALE; MOUSE; NERVE CELL EXCITABILITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BLOTTING, SOUTHERN; BRAIN; CATECHOLAMINES; ELECTROENCEPHALOGRAPHY; EPILEPSY; EPILEPSY, BENIGN NEONATAL; FEMALE; GENE TARGETING; HOMOZYGOTE; KCNQ2 POTASSIUM CHANNEL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; PENTYLENETETRAZOLE; POLYMERASE CHAIN REACTION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 0034126582     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0750028.x     Document Type: Article

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