메뉴 건너뛰기




Volumn 16, Issue 6, 2011, Pages 606-618

Apoptosis induced by an antagonist peptide against HPV16 E7 in vitro and in vivo via restoration of p53

Author keywords

Antagonist peptide; Apoptosis; Cervical cancer; E7 protein; HPV; p53

Indexed keywords

ANTINEOPLASTIC AGENT; PEPTIDE; PEPTIDE PEP 7; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 79955838325     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0594-0     Document Type: Article
Times cited : (8)

References (39)
  • 1
    • 0028810148 scopus 로고
    • The epidemiology of cervical carcinogenesis
    • 8634980 10.1002/1097-0142(19951115)76: 10+<1888::AID- CNCR2820761305>3.0.CO;2-H 1:STN:280:DyaK283ivF2mtA%3D%3D
    • MH Schiffman LA Brinton 1995 The epidemiology of cervical carcinogenesis Cancer 76 10 Suppl 1888 1901 8634980 10.1002/1097-0142(19951115)76:10+<1888:: AID-CNCR2820761305>3.0.CO;2-H 1:STN:280:DyaK283ivF2mtA%3D%3D
    • (1995) Cancer , vol.76 , Issue.10 SUPPL. , pp. 1888-1901
    • Schiffman, M.H.1    Brinton, L.A.2
  • 2
    • 57649229824 scopus 로고    scopus 로고
    • Human papillomavirus 16 E6, E7 siRNAs inhibit proliferation and induce apoptosis of SiHa cervical cancer cells
    • N Chunlian G Guolan H Jie L Hua C Heping H Ming 2008 Human papillomavirus 16 E6, E7 siRNAs inhibit proliferation and induce apoptosis of SiHa cervical cancer cells Chin J Cancer Res 20 4 6
    • (2008) Chin J Cancer Res , vol.20 , Issue.4 , pp. 6
    • Chunlian, N.1    Guolan, G.2    Jie, H.3    Hua, L.4    Heping, C.5    Ming, H.6
  • 3
    • 43249106163 scopus 로고    scopus 로고
    • HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function
    • 18367227 10.1016/j.virol.2008.02.025 1:CAS:528:DC%2BD1cXlvF2rsbg%3D
    • X Liu J Roberts A Dakic Y Zhang R Schlegel 2008 HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function Virology 375 2 611 623 18367227 10.1016/j.virol.2008.02.025 1:CAS:528:DC%2BD1cXlvF2rsbg%3D
    • (2008) Virology , vol.375 , Issue.2 , pp. 611-623
    • Liu, X.1    Roberts, J.2    Dakic, A.3    Zhang, Y.4    Schlegel, R.5
  • 4
    • 0033838826 scopus 로고    scopus 로고
    • Immunotherapy of a human papillomavirus (HPV) type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guerin (BCG) hsp65 and HPV16 E7
    • DOI 10.1046/j.1365-2249.2000.01293.x
    • NR Chu HB Wu T Wu LJ Boux MI Siegel LA Mizzen 2000 Immunotherapy of a human papillomavirus (HPV) type 16 E7-expressing tumour by administration of fusion protein comprising Mycobacterium bovis bacille Calmette-Guerin (BCG) hsp65 and HPV16 E7 Clin Exp Immunol 121 2 216 225 10931134 10.1046/j.1365-2249. 2000.01293.x 1:CAS:528:DC%2BD3cXlvFymur0%3D (Pubitemid 30662070)
    • (2000) Clinical and Experimental Immunology , vol.121 , Issue.2 , pp. 216-225
    • Chu, N.R.1    Wu, H.B.2    Wu, T.-C.3    Boux, L.J.4    Siegel, M.I.5    Mizzen, L.A.6
  • 6
    • 0035043423 scopus 로고    scopus 로고
    • Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein
    • DOI 10.1128/JVI.75.9.4467-4472.2001
    • T Veldman I Horikawa JC Barrett R Schlegel 2001 Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein J Virol 75 9 4467 4472 11287602 10.1128/JVI.75.9.4467-4472.2001 1:CAS:528:DC%2BD3MXivFOkurY%3D (Pubitemid 32410165)
    • (2001) Journal of Virology , vol.75 , Issue.9 , pp. 4467-4472
    • Veldman, T.1    Horikawa, I.2    Barrett, J.C.3    Schlegel, R.4
  • 7
    • 33646147794 scopus 로고    scopus 로고
    • Requirement of E7 oncoprotein for viability of HeLa cells
    • 16500131 10.1016/j.micinf.2005.10.015 1:CAS:528:DC%2BD28XktVGgtL0%3D
    • A Nishimura T Nakahara T Ueno K Sasaki S Yoshida S Kyo, et al. 2006 Requirement of E7 oncoprotein for viability of HeLa cells Microbes Infect 8 4 984 993 16500131 10.1016/j.micinf.2005.10.015 1:CAS:528:DC%2BD28XktVGgtL0%3D
    • (2006) Microbes Infect , vol.8 , Issue.4 , pp. 984-993
    • Nishimura, A.1    Nakahara, T.2    Ueno, T.3    Sasaki, K.4    Yoshida, S.5    Kyo, S.6
  • 8
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 E6 proteins with p53
    • 2157286 10.1126/science.2157286 1:CAS:528:DyaK3cXktF2ltL0%3D
    • BA Werness AJ Levine PM Howley 1990 Association of human papillomavirus types 16 and 18 E6 proteins with p53 Science 248 4951 76 79 2157286 10.1126/science.2157286 1:CAS:528:DyaK3cXktF2ltL0%3D
    • (1990) Science , vol.248 , Issue.4951 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 9
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • DOI 10.1016/0092-8674(93)90384-3
    • M Scheffner JM Huibregtse RD Vierstra PM Howley 1993 The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 Cell 75 3 495 505 8221889 10.1016/0092-8674(93)90384-3 1:CAS:528: DyaK2cXlvFKm (Pubitemid 23335075)
    • (1993) Cell , vol.75 , Issue.3 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 10
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • M Scheffner BA Werness JM Huibregtse AJ Levine PM Howley 1990 The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53 Cell 63 6 1129 1136 2175676 10.1016/0092-8674(90)90409-8 1:CAS:528:DyaK3MXls12itg%3D%3D (Pubitemid 120035062)
    • (1990) Cell , vol.63 , Issue.6 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 11
    • 0344269308 scopus 로고    scopus 로고
    • Human papillomaviruses and associated malignancies
    • RM Alani K Munger 1998 Human papillomaviruses and associated malignancies J Clin Oncol 16 1 330 337 9440761 1:STN:280:DyaK1c7gtFOisw%3D%3D (Pubitemid 28041617)
    • (1998) Journal of Clinical Oncology , vol.16 , Issue.1 , pp. 330-337
    • Alani, R.M.1    Munger, K.2
  • 13
    • 0031930282 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint
    • JT Thomas LA Laimins 1998 Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint J Virol 72 2 1131 1137 9445009 1:CAS:528:DyaK1cXlt1OmsQ%3D%3D (Pubitemid 28116894)
    • (1998) Journal of Virology , vol.72 , Issue.2 , pp. 1131-1137
    • Thomas, J.T.1    Laimins, L.A.2
  • 14
    • 0029093605 scopus 로고
    • Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
    • 7657167 10.1101/gad.9.17.2157 1:CAS:528:DyaK2MXotVOnu7g%3D
    • H Pan AE Griep 1995 Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development Genes Dev 9 17 2157 2169 7657167 10.1101/gad.9.17.2157 1:CAS:528:DyaK2MXotVOnu7g%3D
    • (1995) Genes Dev , vol.9 , Issue.17 , pp. 2157-2169
    • Pan, H.1    Griep, A.E.2
  • 15
    • 1842293961 scopus 로고    scopus 로고
    • 1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein
    • DL Jones K Munger 1997 Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein J Virol 71 4 2905 2912 9060648 1:CAS:528:DyaK2sXhvVGnsbs%3D (Pubitemid 27119932)
    • (1997) Journal of Virology , vol.71 , Issue.4 , pp. 2905-2912
    • Jones, D.L.1    Munger, K.2
  • 16
    • 0029809583 scopus 로고    scopus 로고
    • Apoptosis in human papillomavirus16 E7-, but not E6-immortalized human uroepithelial cells
    • JA Puthenveettil SM Frederickson CA Reznikoff 1996 Apoptosis in human papillomavirus16 E7-, but not E6-immortalized human uroepithelial cells Oncogene 13 6 1123 1131 8808685 1:CAS:528:DyaK28XmtFekurc%3D (Pubitemid 26343564)
    • (1996) Oncogene , vol.13 , Issue.6 , pp. 1123-1131
    • Puthenveettil, J.A.1    Frederickson, S.M.2    Reznikoff, C.A.3
  • 18
    • 0035927583 scopus 로고    scopus 로고
    • The HPV E7 oncoprotein inhibits tumor necrosis factor α-mediated apoptosis in normal human fibroblasts
    • DOI 10.1038/sj.onc.1204483
    • DA Thompson V Zacny GS Belinsky M Classon DL Jones R Schlegel, et al. 2001 The HPV E7 oncoprotein inhibits tumor necrosis factor alpha-mediated apoptosis in normal human fibroblasts Oncogene 20 28 3629 3640 11439326 10.1038/sj.onc.1204483 1:CAS:528:DC%2BD3MXltVKnsL4%3D (Pubitemid 32624955)
    • (2001) Oncogene , vol.20 , Issue.28 , pp. 3629-3640
    • Thompson, D.A.1    Zacny, V.2    Belinsky, G.S.3    Classon, M.4    Jones, D.L.5    Schlegel, R.6    Munger, K.7
  • 19
    • 0032484553 scopus 로고    scopus 로고
    • Induction of apoptosis in human keratinocytes containing mutated p53 alleles and its inhibition by both the E6 and E7 oncoproteins
    • DOI 10.1002/(SICI)1097-0215(19980105) 75:1<96::AID-IJC15>3.0.CO;2-B
    • SS Magal A Jackman XF Pei R Schlegel L Sherman 1998 Induction of apoptosis in human keratinocytes containing mutated p53 alleles and its inhibition by both the E6 and E7 oncoproteins Int J Cancer 75 1 96 104 9426696 10.1002/(SICI)1097-0215(19980105)75:1<96::AID-IJC15>3.0.CO;2-B 1:CAS:528:DyaK1cXjsFyjsQ%3D%3D (Pubitemid 28113983)
    • (1998) International Journal of Cancer , vol.75 , Issue.1 , pp. 96-104
    • Magal, S.S.1    Jackman, A.2    Pei, X.F.3    Schlegel, R.4    Sherman, L.5
  • 21
    • 38149025564 scopus 로고    scopus 로고
    • Protective effect of oxidative stress in HaCaT keratinocytes expressing E7 oncogene
    • 17334903 10.1007/s00726-007-0499-y 1:CAS:528:DC%2BD1cXlt1Cltw%3D%3D
    • JH Shim KH Kim YS Cho HS Choi EY Song PK Myung, et al. 2008 Protective effect of oxidative stress in HaCaT keratinocytes expressing E7 oncogene Amino Acids 34 1 135 141 17334903 10.1007/s00726-007-0499-y 1:CAS:528: DC%2BD1cXlt1Cltw%3D%3D
    • (2008) Amino Acids , vol.34 , Issue.1 , pp. 135-141
    • Shim, J.H.1    Kim, K.H.2    Cho, Y.S.3    Choi, H.S.4    Song, E.Y.5    Myung, P.K.6
  • 22
    • 33748761925 scopus 로고    scopus 로고
    • Chapter 2: the burden of HPV-related cancers S3
    • Parkin DM, Bray F (2006) Chapter 2: the burden of HPV-related cancers. Vaccine 24(Suppl 3):S3/11-25
    • (2006) Vaccine , vol.24 , Issue.SUPPL. 3 , pp. 11-25
    • Parkin, D.M.1    Bray, F.2
  • 24
    • 0032080418 scopus 로고    scopus 로고
    • Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects
    • F Wang-Johanning GY Gillespie J Grim C Rancourt RD Alvarez GP Siegal, et al. 1998 Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects Cancer Res 58 9 1893 1900 9581830 1:CAS:528:DyaK1cXislentrY%3D (Pubitemid 28217464)
    • (1998) Cancer Research , vol.58 , Issue.9 , pp. 1893-1900
    • Wang-Johanning, F.1    Gillespie, G.Y.2    Grim, J.3    Rancourt, C.4    Alvarez, R.D.5    Siegal, G.P.6    Curiel, D.T.7
  • 25
    • 0033103068 scopus 로고    scopus 로고
    • Targetting of the N-terminal domain of the human papillomavirus type 16 E6 oncoprotein with monomeric ScFvs blocks the E6-mediated degradation of cellular p53
    • DOI 10.1002/(SICI)1099-1352(199903/04) 12:2<141::AID-JMR453>3.0. CO;2-O
    • C Giovane G Trave A Briones Y Lutz B Wasylyk E Weiss 1999 Targetting of the N-terminal domain of the human papillomavirus type 16 E6 oncoprotein with monomeric ScFvs blocks the E6-mediated degradation of cellular p53 J Mol Recognit 12 2 141 152 10398405 10.1002/(SICI)1099-1352(199903/04)12:2<141:: AID-JMR453>3.0.CO;2-O 1:CAS:528:DyaK1MXisF2jtrg%3D (Pubitemid 29178089)
    • (1999) Journal of Molecular Recognition , vol.12 , Issue.2 , pp. 141-152
    • Giovane, C.1    Trave, G.2    Briones, A.3    Lutz, Y.4    Wasylyk, B.5    Weiss, E.6
  • 26
    • 0035289707 scopus 로고    scopus 로고
    • Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV-16 E7 oncoprotein
    • 11259377 1:CAS:528:DC%2BD3MXitFWms70%3D
    • S Nauenburg W Zwerschke P Jansen-Durr 2001 Induction of apoptosis in cervical carcinoma cells by peptide aptamers that bind to the HPV-16 E7 oncoprotein FASEB J 15 3 592 594 11259377 1:CAS:528:DC%2BD3MXitFWms70%3D
    • (2001) FASEB J , vol.15 , Issue.3 , pp. 592-594
    • Nauenburg, S.1    Zwerschke, W.2    Jansen-Durr, P.3
  • 27
    • 0142062138 scopus 로고    scopus 로고
    • Chapter 17: genital human papillomavirus infections-current and prospective therapies
    • Stanley M (2003) Chapter 17: genital human papillomavirus infections-current and prospective therapies. J Natl Cancer Inst Monogr (31):117-124
    • (2003) J Natl Cancer Inst Monogr , Issue.31 , pp. 117-124
    • Stanley, M.1
  • 28
    • 34447629237 scopus 로고    scopus 로고
    • Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells
    • DOI 10.1016/j.ygyno.2007.04.039, PII S0090825807002624
    • N Sima S Wang W Wang D Kong Q Xu X Tian, et al. 2007 Antisense targeting human papillomavirus type 16 E6 and E7 genes contributes to apoptosis and senescence in SiHa cervical carcinoma cells Gynecol Oncol 106 2 299 304 17586029 10.1016/j.ygyno.2007.04.039 1:CAS:528:DC%2BD2sXot1ygurs%3D (Pubitemid 47087935)
    • (2007) Gynecologic Oncology , vol.106 , Issue.2 , pp. 299-304
    • Sima, N.1    Wang, S.2    Wang, W.3    Kong, D.4    Xu, Q.5    Tian, X.6    Luo, A.7    Zhou, J.8    Xu, G.9    Meng, L.10    Lu, Y.11    Ma, D.12
  • 29
    • 38649111038 scopus 로고    scopus 로고
    • RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53
    • 18060502 10.1007/s10495-007-0163-8 1:CAS:528:DC%2BD1cXht1SisLw%3D
    • N Sima W Wang D Kong D Deng Q Xu J Zhou, et al. 2008 RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53 Apoptosis 13 2 273 281 18060502 10.1007/s10495-007-0163-8 1:CAS:528:DC%2BD1cXht1SisLw%3D
    • (2008) Apoptosis , vol.13 , Issue.2 , pp. 273-281
    • Sima, N.1    Wang, W.2    Kong, D.3    Deng, D.4    Xu, Q.5    Zhou, J.6
  • 30
    • 33646240852 scopus 로고    scopus 로고
    • Reversal of the malignant phenotype of cervical cancer CaSki cells through adeno-associated virus-mediated delivery of HPV16 E7 antisense RNA
    • 16609012 10.1158/1078-0432.CCR-05-2567 1:CAS:528:DC%2BD28XjtlCiu7o%3D
    • S Wu L Meng S Wang W Wang L Xi X Tian, et al. 2006 Reversal of the malignant phenotype of cervical cancer CaSki cells through adeno-associated virus-mediated delivery of HPV16 E7 antisense RNA Clin Cancer Res 12 7 Pt 1 2032 2037 16609012 10.1158/1078-0432.CCR-05-2567 1:CAS:528:DC%2BD28XjtlCiu7o%3D
    • (2006) Clin Cancer Res , vol.12 , Issue.7 PART 1 , pp. 2032-2037
    • Wu, S.1    Meng, L.2    Wang, S.3    Wang, W.4    Xi, L.5    Tian, X.6
  • 31
    • 0037026601 scopus 로고    scopus 로고
    • Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference
    • 12203116 10.1038/sj.onc.1205878 1:CAS:528:DC%2BD38XmsFGqsL4%3D
    • M Jiang J Milner 2002 Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference Oncogene 21 39 6041 6048 12203116 10.1038/sj.onc.1205878 1:CAS:528:DC%2BD38XmsFGqsL4%3D
    • (2002) Oncogene , vol.21 , Issue.39 , pp. 6041-6048
    • Jiang, M.1    Milner, J.2
  • 32
    • 33751404361 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of human papillomavirus 16 E6/E7 antisense RNA and induction of apoptosis in cervical cancer
    • DOI 10.1016/j.ygyno.2006.06.035, PII S0090825806005142
    • K Hamada T Shirakawa A Gotoh JA Roth M Follen 2006 Adenovirus-mediated transfer of human papillomavirus 16 E6/E7 antisense RNA and induction of apoptosis in cervical cancer Gynecol Oncol 103 3 820 830 16908054 10.1016/j.ygyno.2006.06.035 1:CAS:528:DC%2BD28Xht1KgtLbF (Pubitemid 44821337)
    • (2006) Gynecologic Oncology , vol.103 , Issue.3 , pp. 820-830
    • Hamada, K.1    Shirakawa, T.2    Gotoh, A.3    Roth, J.A.4    Follen, M.5
  • 33
    • 0028508635 scopus 로고
    • Papillomaviruses as targets for cancer gene therapy
    • 7621251 1:CAS:528:DyaK2MXhvFOhu7g%3D
    • EJ Shillitoe P Kamath Z Chen 1994 Papillomaviruses as targets for cancer gene therapy Cancer Gene Ther 1 3 193 204 7621251 1:CAS:528:DyaK2MXhvFOhu7g%3D
    • (1994) Cancer Gene Ther , vol.1 , Issue.3 , pp. 193-204
    • Shillitoe, E.J.1    Kamath, P.2    Chen, Z.3
  • 34
    • 57949096387 scopus 로고    scopus 로고
    • Search for the Higgs boson produced in association with Z → l+l in pp collisions at sqrt[s] = 1.96 TeV
    • 19113696 10.1103/PhysRevLett.101.251803
    • T Aaltonen J Adelman T Akimoto MG Albrow B Alvarez Gonzalez S Amerio, et al. 2008 Search for the Higgs boson produced in association with Z → l+l in pp collisions at sqrt[s] = 1.96 TeV Phys Rev Lett 101 25 251803 19113696 10.1103/PhysRevLett.101.251803
    • (2008) Phys Rev Lett , vol.101 , Issue.25 , pp. 251803
    • Aaltonen, T.1    Adelman, J.2    Akimoto, T.3    Albrow, M.G.4    Alvarez Gonzalez, B.5    Amerio, S.6
  • 35
    • 33847226329 scopus 로고    scopus 로고
    • Characterization of antibodies in single-chain format against the E7 oncoprotein of the human papillomavirus type 16 and their improvement by mutagenesis
    • 17266749 10.1186/1471-2407-7-25
    • MG Dona C Giorgi L Accardi 2007 Characterization of antibodies in single-chain format against the E7 oncoprotein of the human papillomavirus type 16 and their improvement by mutagenesis BMC Cancer 7 25 17266749 10.1186/1471-2407-7-25
    • (2007) BMC Cancer , vol.7 , pp. 25
    • Dona, M.G.1    Giorgi, C.2    Accardi, L.3
  • 36
    • 0142250356 scopus 로고    scopus 로고
    • Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck
    • H Niwa AL Wentzel M Li WE Gooding VW Lui JR Grandis 2003 Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck Clin Cancer Res 9 13 5028 5035 14581378 1:CAS:528:DC%2BD3sXosVGjtbs%3D (Pubitemid 37323310)
    • (2003) Clinical Cancer Research , vol.9 , Issue.13 , pp. 5028-5035
    • Niwa, H.1    Wentzel, A.L.2    Li, M.3    Gooding, W.E.4    Lui, V.W.Y.5    Grandis, J.R.6
  • 37
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
    • DOI 10.1084/jem.20050967
    • E Passegue AJ Wagers S Giuriato WC Anderson IL Weissman 2005 Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates J Exp Med 202 11 1599 1611 16330818 10.1084/jem.20050967 1:CAS:528:DC%2BD2MXhtlSqtLbL (Pubitemid 41746605)
    • (2005) Journal of Experimental Medicine , vol.202 , Issue.11 , pp. 1599-1611
    • Passegue, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 38
    • 0029979182 scopus 로고    scopus 로고
    • Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas. Correlation with cyclin D1 (PRAD1/CCND1) mRNA levels and proliferative activity
    • 8623927 1:STN:280:DyaK283gvVWgtg%3D%3D
    • P Jares E Campo M Pinyol F Bosch R Miquel PL Fernandez, et al. 1996 Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas. Correlation with cyclin D1 (PRAD1/CCND1) mRNA levels and proliferative activity Am J Pathol 148 5 1591 1600 8623927 1:STN:280:DyaK283gvVWgtg%3D%3D
    • (1996) Am J Pathol , vol.148 , Issue.5 , pp. 1591-1600
    • Jares, P.1    Campo, E.2    Pinyol, M.3    Bosch, F.4    Miquel, R.5    Fernandez, P.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.