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Volumn 6, Issue 4, 2011, Pages

Comparative lipidomics of azole sensitive and resistant clinical isolates of candida albicans reveals unexpected diversity in molecular lipid imprints

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; CACDR1P PROTEIN; CAMDR1P PROTEIN; CHOLESTEROL ESTER; GLYCEROPHOSPHOLIPID; LIPIDOME; MANNOSYLINOSITOL PHOSPHORYLCERAMIDE; MONOUNSATURATED FATTY ACID; PHOSPHATIDYLSERINE; POLYUNSATURATED FATTY ACID; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG; CERAMIDE; ESTER; LIPID; MANNOSE; SPHINGOLIPID; STEROL;

EID: 79955777587     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019266     Document Type: Article
Times cited : (44)

References (53)
  • 1
    • 24144451315 scopus 로고    scopus 로고
    • Changing patterns and trends in systemic fungal infections
    • Richardson MD, (2005) Changing patterns and trends in systemic fungal infections. J Antimicrob Chemother 56: i5-i11.
    • (2005) J Antimicrob Chemother , vol.56
    • Richardson, M.D.1
  • 2
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem
    • Pfaller MA, Diekema DJ, (2007) Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem. Clinical Microbiology Reviews 20: 133-163.
    • (2007) Clinical Microbiology Reviews , vol.20 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 3
    • 0036916341 scopus 로고    scopus 로고
    • Recent trends in the epidemiology of invasive mycoses
    • Clark TA, Hajjeh RA, (2002) Recent trends in the epidemiology of invasive mycoses. Curr Opin Infect Dis 15: 569-574.
    • (2002) Curr Opin Infect Dis , vol.15 , pp. 569-574
    • Clark, T.A.1    Hajjeh, R.A.2
  • 5
    • 10444285332 scopus 로고    scopus 로고
    • Multidrug resistance in yeast Candida
    • Prasad R, Kapoor K, (2005) Multidrug resistance in yeast Candida. Int Rev Cytol 242: 215-248.
    • (2005) Int Rev Cytol , vol.242 , pp. 215-248
    • Prasad, R.1    Kapoor, K.2
  • 6
    • 0031969879 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular factors that contribute to antifungal drug resistance
    • White TC, Marr KA, Bowden RA, (1998) Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clinical Microbiology Reviews 11: 382-402.
    • (1998) Clinical Microbiology Reviews , vol.11 , pp. 382-402
    • White, T.C.1    Marr, K.A.2    Bowden, R.A.3
  • 7
    • 70350026151 scopus 로고    scopus 로고
    • Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation
    • Sanglard D, Coste A, Ferrari S, (2009) Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation. FEMS Yeast Res 9: 1029-1050.
    • (2009) FEMS Yeast Res , vol.9 , pp. 1029-1050
    • Sanglard, D.1    Coste, A.2    Ferrari, S.3
  • 8
    • 68249116196 scopus 로고    scopus 로고
    • Chapter 14 -Molecular Principles of Antifungal Drug Resistance
    • In: Heitman J, Filler SG, Edwards JE, Mitchell AP, editors, Washington, D.C., ASM Press
    • Sanglard D, White TC, (2005) Chapter 14-Molecular Principles of Antifungal Drug Resistance. In: Heitman J, Filler SG, Edwards JE, Mitchell AP, editors. Molecular principles of fungal pathogenesis Washington, D.C. ASM Press pp. 197-212.
    • (2005) Molecular Principles of Fungal Pathogenesis , pp. 197-212
    • Sanglard, D.1    White, T.C.2
  • 9
    • 38649112299 scopus 로고    scopus 로고
    • Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts
    • Pasrija R, Panwar SL, Prasad R, (2008) Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts. Antimicrob Agents Chemother 52: 694-704.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 694-704
    • Pasrija, R.1    Panwar, S.L.2    Prasad, R.3
  • 10
    • 2142645082 scopus 로고    scopus 로고
    • Membrane Sphingolipid- Ergosterol interactions are important determinants of Multidrug Resistance in Candida albicans
    • Mukhopadhyay K, Prasad T, Saini P, Pucadyil TJ, Chattopadhyay A, et al. (2004) Membrane Sphingolipid- Ergosterol interactions are important determinants of Multidrug Resistance in Candida albicans. Antimicrob Agents Chemother 48: 1778-1787.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 1778-1787
    • Mukhopadhyay, K.1    Prasad, T.2    Saini, P.3    Pucadyil, T.J.4    Chattopadhyay, A.5
  • 11
    • 27844543339 scopus 로고    scopus 로고
    • Membrane raft lipid constituents affect drug susceptibilities of Candida albicans
    • Pasrija R, Prasad T, Prasad R, (2005) Membrane raft lipid constituents affect drug susceptibilities of Candida albicans. Biochem Soc Trans 33: 1219-1223.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1219-1223
    • Pasrija, R.1    Prasad, T.2    Prasad, R.3
  • 12
    • 0037130284 scopus 로고    scopus 로고
    • The genetic basis of fluconazole resistance development in Candida albicans
    • Morschhauser J, (2002) The genetic basis of fluconazole resistance development in Candida albicans. Biochim Biophys Acta 1587: 240-248.
    • (2002) Biochim Biophys Acta , vol.1587 , pp. 240-248
    • Morschhauser, J.1
  • 13
    • 79951972302 scopus 로고    scopus 로고
    • Genetic Basis of Antifungal Drug Resistance
    • Marie C, White TC, (2009) Genetic Basis of Antifungal Drug Resistance. Curr Fungal Infect Rep 3: 163-169.
    • (2009) Curr Fungal Infect Rep , vol.3 , pp. 163-169
    • Marie, C.1    White, T.C.2
  • 14
    • 0036208102 scopus 로고    scopus 로고
    • In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry
    • Kohli A, Smriti, Mukhopadhyay K, Rattan A, Prasad R, (2002) In vitro low-level resistance to azoles in Candida albicans is associated with changes in membrane lipid fluidity and asymmetry. Antimicrob Agents Chemother 46: 1046-1052.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1046-1052
    • Kohli, A.1    Smriti2    Mukhopadhyay, K.3    Rattan, A.4    Prasad, R.5
  • 15
    • 0036894215 scopus 로고    scopus 로고
    • Drug susceptibilities of yeast cells are affected by membrane lipid composition
    • Mukhopadhyay K, Kohli A, Prasad R, (2002) Drug susceptibilities of yeast cells are affected by membrane lipid composition. Antimicrob Agents Chemother 46: 3695-3705.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 3695-3705
    • Mukhopadhyay, K.1    Kohli, A.2    Prasad, R.3
  • 16
    • 22144478635 scopus 로고    scopus 로고
    • The emerging field of lipidomics
    • Wenk MR, (2005) The emerging field of lipidomics. Nat Rev Drug Discov 4: 594-610.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 594-610
    • Wenk, M.R.1
  • 17
    • 33845564160 scopus 로고    scopus 로고
    • Lipidomics: A global approach to lipid analysis in biological systems
    • Watson AD, (2006) Lipidomics: A global approach to lipid analysis in biological systems. J Lipid Res 47: 2101-2111.
    • (2006) J Lipid Res , vol.47 , pp. 2101-2111
    • Watson, A.D.1
  • 18
    • 33646068088 scopus 로고    scopus 로고
    • Metabolipidomics: profiling metabolism of glycerophospholipid species by stable isotopic precursors and tandem mass spectrometry
    • Bleijerveld OB, Houweling M, Thomas MJ, Cui Z, (2006) Metabolipidomics: profiling metabolism of glycerophospholipid species by stable isotopic precursors and tandem mass spectrometry. Anal Biochem 352: 1-14.
    • (2006) Anal Biochem , vol.352 , pp. 1-14
    • Bleijerveld, O.B.1    Houweling, M.2    Thomas, M.J.3    Cui, Z.4
  • 21
    • 0022539316 scopus 로고
    • The lipid composition of azole-sensitive and azole-resistant strains of Candida albicans
    • Hitchcock CA, Barrett-Bee KJ, Russell NJ, (1986) The lipid composition of azole-sensitive and azole-resistant strains of Candida albicans. J Gen Microbiol 132: 2421-2431.
    • (1986) J Gen Microbiol , vol.132 , pp. 2421-2431
    • Hitchcock, C.A.1    Barrett-Bee, K.J.2    Russell, N.J.3
  • 22
    • 0034176596 scopus 로고    scopus 로고
    • Phospholipid and sterol analysis of plasma membranes of azole-resistant Candida albicans strains
    • Loffler J, Einsele H, Hebart H, Schumacher U, Hrastnik C, et al. (2000) Phospholipid and sterol analysis of plasma membranes of azole-resistant Candida albicans strains. FEMS Microbiol Lett 185: 59-63.
    • (2000) FEMS Microbiol Lett , vol.185 , pp. 59-63
    • Loffler, J.1    Einsele, H.2    Hebart, H.3    Schumacher, U.4    Hrastnik, C.5
  • 23
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ, (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 24
    • 33747871812 scopus 로고    scopus 로고
    • Quantitative profiling of polar glycerolipid species from organs of wild-type Arabidopsis and a phospholipase Dalpha1 knockout mutant
    • Devaiah SP, Roth MR, Baughman E, Li M, Tamura P, et al. (2006) Quantitative profiling of polar glycerolipid species from organs of wild-type Arabidopsis and a phospholipase Dalpha1 knockout mutant. Phytochemistry 67: 1907-1924.
    • (2006) Phytochemistry , vol.67 , pp. 1907-1924
    • Devaiah, S.P.1    Roth, M.R.2    Baughman, E.3    Li, M.4    Tamura, P.5
  • 25
    • 78649716032 scopus 로고    scopus 로고
    • Phospholipidome of Candida: each species of Candida has distinctive phospholipid molecular species
    • Singh A, Prasad T, Kapoor K, Mandal A, Roth M, et al. (2010) Phospholipidome of Candida: each species of Candida has distinctive phospholipid molecular species. OMICS 14: 665-677.
    • (2010) OMICS , vol.14 , pp. 665-677
    • Singh, A.1    Prasad, T.2    Kapoor, K.3    Mandal, A.4    Roth, M.5
  • 26
    • 0037199955 scopus 로고    scopus 로고
    • Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis
    • Welti R, Li W, Li M, Sang Y, Biesiada H, et al. (2002) Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis. J Biol Chem 277: 31994-32002.
    • (2002) J Biol Chem , vol.277 , pp. 31994-32002
    • Welti, R.1    Li, W.2    Li, M.3    Sang, Y.4    Biesiada, H.5
  • 27
    • 0032888237 scopus 로고    scopus 로고
    • Molecular aspects of fluconazole resistance development in Candida albicans
    • Franz R, Ruhnke M, Morschhauser J, (1999) Molecular aspects of fluconazole resistance development in Candida albicans. Mycoses 42: 453-458.
    • (1999) Mycoses , vol.42 , pp. 453-458
    • Franz, R.1    Ruhnke, M.2    Morschhauser, J.3
  • 28
    • 3342996550 scopus 로고    scopus 로고
    • Comparison of Gene Expression Profiles of Candida albicans Azole-Resistant Clinical Isolates and Laboratory Strains Exposed to Drugs Inducing Multidrug Transporters
    • Karababa M, Coste AT, Rognon B, Bille J, Sanglard D, (2004) Comparison of Gene Expression Profiles of Candida albicans Azole-Resistant Clinical Isolates and Laboratory Strains Exposed to Drugs Inducing Multidrug Transporters. Antimicrob Agents Chemother 48: 3064-3079.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3064-3079
    • Karababa, M.1    Coste, A.T.2    Rognon, B.3    Bille, J.4    Sanglard, D.5
  • 29
    • 0031759244 scopus 로고    scopus 로고
    • Multiple molecular mechanisms contribute to a stepwise development of fluconazole resistance in clinical Candida albicans strains
    • Franz R, Kelly SL, Lamb DC, Kelly DE, Ruhnke M, et al. (1998) Multiple molecular mechanisms contribute to a stepwise development of fluconazole resistance in clinical Candida albicans strains. Antimicrob Agents Chemother 42: 3065-3072.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3065-3072
    • Franz, R.1    Kelly, S.L.2    Lamb, D.C.3    Kelly, D.E.4    Ruhnke, M.5
  • 30
    • 0034081664 scopus 로고    scopus 로고
    • Target gene disruption in Candida albicans wild-type strains: the role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates
    • Wisching S, Michel S, Morschhauser J, (2000) Target gene disruption in Candida albicans wild-type strains: the role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates. Mol Microbiol 36: 856-865.
    • (2000) Mol Microbiol , vol.36 , pp. 856-865
    • Wisching, S.1    Michel, S.2    Morschhauser, J.3
  • 31
    • 0028080105 scopus 로고
    • Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipids
    • Han X, Gross RW, (1994) Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipids. Proc Natl Acad Sci USA 91: 10635-10639.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10635-10639
    • Han, X.1    Gross, R.W.2
  • 32
    • 77954956306 scopus 로고    scopus 로고
    • Lipidomics: coming to grips with lipid diversity
    • Shevchenko A, Simons K, (2010) Lipidomics: coming to grips with lipid diversity. Nat Rev Mol Cell Biol 11: 593-598.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 593-598
    • Shevchenko, A.1    Simons, K.2
  • 33
    • 40449141013 scopus 로고    scopus 로고
    • What is principal component analysis?
    • Ringner M, (2008) What is principal component analysis? Nat Biotechnol 26: 303-304.
    • (2008) Nat Biotechnol , vol.26 , pp. 303-304
    • Ringner, M.1
  • 35
    • 77349103477 scopus 로고    scopus 로고
    • Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans
    • Chen YL, Montedonico AE, Kauff an S, Dunlap JR, Menn FM, et al. (2010) Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans. Mol Microbiol 75: 1112-1132.
    • (2010) Mol Microbiol , vol.75 , pp. 1112-1132
    • Chen, Y.L.1    Montedonico, A.E.2    Kauff an, S.3    Dunlap, J.R.4    Menn, F.M.5
  • 36
    • 42249110690 scopus 로고    scopus 로고
    • Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata
    • Batova M, Borecka-Melkusova S, Simockova M, Dzugasova V, Goffa E, et al. (2008) Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata. Curr Genet 53: 313-322.
    • (2008) Curr Genet , vol.53 , pp. 313-322
    • Batova, M.1    Borecka-Melkusova, S.2    Simockova, M.3    Dzugasova, V.4    Goffa, E.5
  • 37
    • 0019332349 scopus 로고
    • Activation of calcium and phospholipid dependent protein-kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover
    • Kishimoto A, Takai Y, Mori T, Kikkawa U, Nishizuka Y, (1980) Activation of calcium and phospholipid dependent protein-kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover. J Biol Chem 255: 2273-2276.
    • (1980) J Biol Chem , vol.255 , pp. 2273-2276
    • Kishimoto, A.1    Takai, Y.2    Mori, T.3    Kikkawa, U.4    Nishizuka, Y.5
  • 38
    • 0018803639 scopus 로고
    • Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid dependent protein-kinase system
    • Takai Y, Kishimoto A, Kikkawa U, Mori T, Nishizuka Y, (1979) Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid dependent protein-kinase system. Biochem Biophys Res Commun 91: 1218-1224.
    • (1979) Biochem Biophys Res Commun , vol.91 , pp. 1218-1224
    • Takai, Y.1    Kishimoto, A.2    Kikkawa, U.3    Mori, T.4    Nishizuka, Y.5
  • 39
    • 0027232834 scopus 로고
    • Interaction of proteins with lipid head groups: lessons from protein kinase C
    • Newton AC, (1993) Interaction of proteins with lipid head groups: lessons from protein kinase C. Annu Rev Biophys Biomol Struct 22: 1-25.
    • (1993) Annu Rev Biophys Biomol Struct , vol.22 , pp. 1-25
    • Newton, A.C.1
  • 40
    • 0028341564 scopus 로고
    • Phosphatidyl-l-serine is necessary for protein kinase C's high-affinity interaction with diacylglycerol-containing membranes
    • Newton AC, Keranen LM, (1994) Phosphatidyl-l-serine is necessary for protein kinase C's high-affinity interaction with diacylglycerol-containing membranes. Biochemistry 33: 6651-6658.
    • (1994) Biochemistry , vol.33 , pp. 6651-6658
    • Newton, A.C.1    Keranen, L.M.2
  • 41
    • 0035204169 scopus 로고    scopus 로고
    • Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C
    • Madani S, Hichami A, Legrand A, Belleville J, Khan NA, (2001) Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J 15: 2595-2601.
    • (2001) FASEB J , vol.15 , pp. 2595-2601
    • Madani, S.1    Hichami, A.2    Legrand, A.3    Belleville, J.4    Khan, N.A.5
  • 42
    • 33947603008 scopus 로고    scopus 로고
    • Protein kinase C and other diacylglycerol effectors in cancer
    • Griner EM, Kazanietz MG, (2007) Protein kinase C and other diacylglycerol effectors in cancer. Nat Rev Cancer 7: 281-294.
    • (2007) Nat Rev Cancer , vol.7 , pp. 281-294
    • Griner, E.M.1    Kazanietz, M.G.2
  • 43
    • 77958121046 scopus 로고    scopus 로고
    • PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90
    • doi:10.1371/journal.ppat.1001069
    • LaFayette SL, Collins C, Zaas AK, Schell WA, Betancourt-Quiroz M, et al. (2010) PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90. PLoS Pathog 6: e1001069 doi:10.1371/journal.ppat.1001069.
    • (2010) PLoS Pathog , vol.6
    • LaFayette, S.L.1    Collins, C.2    Zaas, A.K.3    Schell, W.A.4    Betancourt-Quiroz, M.5
  • 44
    • 70049108302 scopus 로고    scopus 로고
    • Hsp90 Orchestrates Stress Response Signaling Governing Fungal Drug Resistance
    • doi:10.1371/journal.ppat.1000471
    • Cowen LE, (2009) Hsp90 Orchestrates Stress Response Signaling Governing Fungal Drug Resistance. PLoS Pathog 5: e1000471 doi:10.1371/journal.ppat.1000471.
    • (2009) PLoS Pathog , vol.5
    • Cowen, L.E.1
  • 45
    • 7044241302 scopus 로고    scopus 로고
    • How lipids affect the activities of integral membrane proteins
    • Lee AG, (2004) How lipids affect the activities of integral membrane proteins. Biochim Biophys Acta 1666: 62-87.
    • (2004) Biochim Biophys Acta , vol.1666 , pp. 62-87
    • Lee, A.G.1
  • 46
    • 27844436560 scopus 로고    scopus 로고
    • Specific protein-lipid interactions in membrane proteins
    • Hunte C, (2005) Specific protein-lipid interactions in membrane proteins. Biochem Soc Trans 33: 938-942.
    • (2005) Biochem Soc Trans , vol.33 , pp. 938-942
    • Hunte, C.1
  • 47
    • 0035979797 scopus 로고    scopus 로고
    • Overexpression of mammalian integral membrane proteins for structural studies
    • Tate CG, (2001) Overexpression of mammalian integral membrane proteins for structural studies. FEBS Lett 504: 94-98.
    • (2001) FEBS Lett , vol.504 , pp. 94-98
    • Tate, C.G.1
  • 49
    • 52649131910 scopus 로고    scopus 로고
    • Evidence for the bifunctional nature of mitochondrial phosphatidylserine decarboxylase: role in Pdr3-dependent retrograde regulation of PDR5 expression
    • Gulshan K, Schmidt JA, Shahi P, Moye-Rowley WS, (2008) Evidence for the bifunctional nature of mitochondrial phosphatidylserine decarboxylase: role in Pdr3-dependent retrograde regulation of PDR5 expression. Mol Cell Biol 28 (19): 5851-64.
    • (2008) Mol Cell Biol , vol.28 , Issue.19 , pp. 5851-5864
    • Gulshan, K.1    Schmidt, J.A.2    Shahi, P.3    Moye-Rowley, W.S.4
  • 50
    • 64649088477 scopus 로고    scopus 로고
    • Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi
    • Shahi P, Moye-Rowley WS, (2009) Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi. Biochim Biophys Acta 1794 (5): 852-859.
    • (2009) Biochim Biophys Acta , vol.1794 , Issue.5 , pp. 852-859
    • Shahi, P.1    Moye-Rowley, W.S.2
  • 51
    • 0035979797 scopus 로고    scopus 로고
    • Overexpression of mammalian integral membrane proteins for structural studies
    • Tate CG, (2001) Overexpression of mammalian integral membrane proteins for structural studies. FEBS Lett 504: 94-98.
    • (2001) FEBS Lett , vol.504 , pp. 94-98
    • Tate, C.G.1
  • 52
    • 15844379770 scopus 로고    scopus 로고
    • A phospholipid acts as a chaperone in assembly of a membrane transport protein
    • Bogdanov M, Jianzhong Sun J, Kaback HR, Dowhan W, (1996) A phospholipid acts as a chaperone in assembly of a membrane transport protein. J Biol Chem 271: 11615-11618.
    • (1996) J Biol Chem , vol.271 , pp. 11615-11618
    • Bogdanov, M.1    Jianzhong Sun, J.2    Kaback, H.R.3    Dowhan, W.4
  • 53
    • 0033617356 scopus 로고    scopus 로고
    • Phospholipid-assisted refolding of an integral membrane protein. Minimum structural features for phosphatidylethanolamine to act as a molecular chaperone
    • Bogdanov M, Umeda M, Dowhan W, (1999) Phospholipid-assisted refolding of an integral membrane protein. Minimum structural features for phosphatidylethanolamine to act as a molecular chaperone. J Biol Chem 274: 12339-12345.
    • (1999) J Biol Chem , vol.274 , pp. 12339-12345
    • Bogdanov, M.1    Umeda, M.2    Dowhan, W.3


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