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Volumn 1794, Issue 5, 2009, Pages 852-859

Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi

Author keywords

ABC transporter; Candida albicans; Candida glabrata; Multidrug resistance; Phospholipid asymmetry; Saccharomyces cerevisiae; Sphingolipid; Transcription

Indexed keywords

ABC TRANSPORTER; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHOLIPID; PROTEIN SCPDR1; PROTEIN SCPDR16; PROTEIN SCPDR3; PROTEIN SCPDR5; PROTEIN YOR1; SPHINGOLIPID; UNCLASSIFIED DRUG;

EID: 64649088477     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.12.012     Document Type: Review
Times cited : (47)

References (95)
  • 1
    • 22744455661 scopus 로고    scopus 로고
    • An update on antifungal targets and mechanisms of resistance in Candida albicans
    • Akins R.A. An update on antifungal targets and mechanisms of resistance in Candida albicans. Med. Mycol. 43 (2005) 285-318
    • (2005) Med. Mycol. , vol.43 , pp. 285-318
    • Akins, R.A.1
  • 2
    • 0023603366 scopus 로고
    • The multidrug resistance gene PDR1 from Saccharomyces cerevisiae
    • Balzi E., Chen W., Ulaszewski S., Capieaux E., and Goffeau A. The multidrug resistance gene PDR1 from Saccharomyces cerevisiae. J. Biol. Chem. 262 (1987) 16871-16879
    • (1987) J. Biol. Chem. , vol.262 , pp. 16871-16879
    • Balzi, E.1    Chen, W.2    Ulaszewski, S.3    Capieaux, E.4    Goffeau, A.5
  • 3
    • 0024518932 scopus 로고
    • The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex
    • Bankaitis V.A., Malehorn D.E., Emr S.D., and Greene R. The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex. J. Cell Biol. 108 (1989) 1271-1281
    • (1989) J. Cell Biol. , vol.108 , pp. 1271-1281
    • Bankaitis, V.A.1    Malehorn, D.E.2    Emr, S.D.3    Greene, R.4
  • 4
    • 0032720231 scopus 로고    scopus 로고
    • Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance
    • Bauer B.E., Wolfger H., and Kuchler K. Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim. Biophys. Acta 1461 (1999) 217-236
    • (1999) Biochim. Biophys. Acta , vol.1461 , pp. 217-236
    • Bauer, B.E.1    Wolfger, H.2    Kuchler, K.3
  • 5
    • 0030671457 scopus 로고    scopus 로고
    • Molecular and phenotypic characterization of yeast PDR1 mutants that show hyperactive transcription of various ABC multidrug transporter genes
    • Carvajal E., van den Hazel H.B., Cybularz-Kolaczkowska A., Balzi E., and Goffeau A. Molecular and phenotypic characterization of yeast PDR1 mutants that show hyperactive transcription of various ABC multidrug transporter genes. Mol. Gen. Genet. 256 (1997) 406-415
    • (1997) Mol. Gen. Genet. , vol.256 , pp. 406-415
    • Carvajal, E.1    van den Hazel, H.B.2    Cybularz-Kolaczkowska, A.3    Balzi, E.4    Goffeau, A.5
  • 6
    • 0034625349 scopus 로고    scopus 로고
    • Sphingolipids signal heat stress-induced ubiquitin-dependent proteolysis
    • Chung N., Jenkins G., Hannun Y.A., Heitman J., and Obeid L.M. Sphingolipids signal heat stress-induced ubiquitin-dependent proteolysis. J. Biol. Chem. 275 (2000) 17229-17232
    • (2000) J. Biol. Chem. , vol.275 , pp. 17229-17232
    • Chung, N.1    Jenkins, G.2    Hannun, Y.A.3    Heitman, J.4    Obeid, L.M.5
  • 7
    • 0027423244 scopus 로고
    • Cloning of a gene (PSD1) encoding phosphatidylserine decarboxylase from Saccharomyces cerevisiae by complementation of an Escherichia coli mutant
    • Clancey C.J., Chang S.C., and Dowhan W. Cloning of a gene (PSD1) encoding phosphatidylserine decarboxylase from Saccharomyces cerevisiae by complementation of an Escherichia coli mutant. J. Biol. Chem. 268 (1993) 24580-24590
    • (1993) J. Biol. Chem. , vol.268 , pp. 24580-24590
    • Clancey, C.J.1    Chang, S.C.2    Dowhan, W.3
  • 8
    • 11144270183 scopus 로고    scopus 로고
    • TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2
    • Coste A.T., Karababa M., Ischer F., Bille J., and Sanglard D. TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2. Eukaryot. Cell 3 (2004) 1639-1652
    • (2004) Eukaryot. Cell , vol.3 , pp. 1639-1652
    • Coste, A.T.1    Karababa, M.2    Ischer, F.3    Bille, J.4    Sanglard, D.5
  • 9
    • 33947238877 scopus 로고    scopus 로고
    • Yeast sphingolipids: recent developments in understanding biosynthesis, regulation and function
    • Cowart L.A., and Obeid L.M. Yeast sphingolipids: recent developments in understanding biosynthesis, regulation and function. Biochim. Biophys. Acta 1771 (2007) 421-431
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 421-431
    • Cowart, L.A.1    Obeid, L.M.2
  • 10
    • 0027300506 scopus 로고
    • Heat shock proteins: molecular chaperones of protein biogenesis
    • Craig E.A., Gambill B.D., and Nelson R.J. Heat shock proteins: molecular chaperones of protein biogenesis. Micro. Revs. 57 (1993) 402-414
    • (1993) Micro. Revs. , vol.57 , pp. 402-414
    • Craig, E.A.1    Gambill, B.D.2    Nelson, R.J.3
  • 11
    • 0032617223 scopus 로고    scopus 로고
    • Functional analysis of the promoter of the yeast SNQ2 gene encoding a multidrug resistance transporter that confers the resistance to 4-nitroquinoline-N-oxide
    • Cui Z., Hirata D., and Miyakawa T. Functional analysis of the promoter of the yeast SNQ2 gene encoding a multidrug resistance transporter that confers the resistance to 4-nitroquinoline-N-oxide. Biosci. Biotechnol. Biochem. 63 (1999) 162-167
    • (1999) Biosci. Biotechnol. Biochem. , vol.63 , pp. 162-167
    • Cui, Z.1    Hirata, D.2    Miyakawa, T.3
  • 12
    • 15844430252 scopus 로고    scopus 로고
    • The mutidrug resistance-associated protein (MRP) subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions
    • Cui Z., Hirata D., Tsuchiya E., Osada H., and Miyakawa T. The mutidrug resistance-associated protein (MRP) subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions. J. Biol. Chem. 271 (1996) 14712-14716
    • (1996) J. Biol. Chem. , vol.271 , pp. 14712-14716
    • Cui, Z.1    Hirata, D.2    Tsuchiya, E.3    Osada, H.4    Miyakawa, T.5
  • 13
    • 0031655755 scopus 로고    scopus 로고
    • Yeast gene YRR1, which is required for resistance to 4-nitroquinoline-N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2
    • Cui Z., Shiraki T., Hirata D., and Miyakawa T. Yeast gene YRR1, which is required for resistance to 4-nitroquinoline-N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2. Mol. Microbiol. 29 (1998) 1307-1315
    • (1998) Mol. Microbiol. , vol.29 , pp. 1307-1315
    • Cui, Z.1    Shiraki, T.2    Hirata, D.3    Miyakawa, T.4
  • 14
    • 0036223414 scopus 로고    scopus 로고
    • A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance
    • de Micheli M., Bille J., Schueller C., and Sanglard D. A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance. Mol. Microbiol. 43 (2002) 1197-1214
    • (2002) Mol. Microbiol. , vol.43 , pp. 1197-1214
    • de Micheli, M.1    Bille, J.2    Schueller, C.3    Sanglard, D.4
  • 16
    • 0029042698 scopus 로고
    • Positive autoregulation of the yeast transcription factor Pdr3p, involved in the control of the drug resistance phenomenon
    • Delahodde A., Delaveau T., and Jacq C. Positive autoregulation of the yeast transcription factor Pdr3p, involved in the control of the drug resistance phenomenon. Mol. Cell. Biol. 15 (1995) 4043-4051
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4043-4051
    • Delahodde, A.1    Delaveau, T.2    Jacq, C.3
  • 17
    • 0027998450 scopus 로고
    • PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon
    • Delaveau T., Delahodde A., Carvajal E., Subik J., and Jacq C. PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon. Mol. Gen. Genet. 244 (1994) 501-511
    • (1994) Mol. Gen. Genet. , vol.244 , pp. 501-511
    • Delaveau, T.1    Delahodde, A.2    Carvajal, E.3    Subik, J.4    Jacq, C.5
  • 18
    • 0034708797 scopus 로고    scopus 로고
    • Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants
    • DeRisi J., van den Hazel B., Marc P., Balzi E., Brown P., Jacq C., and Goffeau A. Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants. FEBS Lett. 470 (2000) 156-160
    • (2000) FEBS Lett. , vol.470 , pp. 156-160
    • DeRisi, J.1    van den Hazel, B.2    Marc, P.3    Balzi, E.4    Brown, P.5    Jacq, C.6    Goffeau, A.7
  • 19
    • 0028154080 scopus 로고
    • Mutations in the yeast PDR3, PDR4, PDR7 and PDR9 pleiotropic drug resistance loci affect the transcript level of an ATP binding cassette transporter encoding gene, PDR5
    • Dexter D., Moye-Rowley W.S., Wu A.L., and Golin J. Mutations in the yeast PDR3, PDR4, PDR7 and PDR9 pleiotropic drug resistance loci affect the transcript level of an ATP binding cassette transporter encoding gene, PDR5. Genetics 136 (1994) 505-515
    • (1994) Genetics , vol.136 , pp. 505-515
    • Dexter, D.1    Moye-Rowley, W.S.2    Wu, A.L.3    Golin, J.4
  • 20
    • 0037071871 scopus 로고    scopus 로고
    • Sphingolipid functions in Saccharomyces cerevisiae
    • Dickson R.C., and Lester R.L. Sphingolipid functions in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1583 (2002) 13-25
    • (2002) Biochim. Biophys. Acta , vol.1583 , pp. 13-25
    • Dickson, R.C.1    Lester, R.L.2
  • 21
    • 0030669755 scopus 로고    scopus 로고
    • Synthesis of mannose-(inositol-P)2-ceramide, the major sphingolipid in Saccharomyces cerevisiae, requires the IPT1 (YDR072c) gene
    • Dickson R.C., Nagiec E.E., Wells G.B., Nagiec M.M., and Lester R.L. Synthesis of mannose-(inositol-P)2-ceramide, the major sphingolipid in Saccharomyces cerevisiae, requires the IPT1 (YDR072c) gene. J. Biol. Chem. 272 (1997) 29620-29625
    • (1997) J. Biol. Chem. , vol.272 , pp. 29620-29625
    • Dickson, R.C.1    Nagiec, E.E.2    Wells, G.B.3    Nagiec, M.M.4    Lester, R.L.5
  • 23
    • 3142557997 scopus 로고    scopus 로고
    • Activation of pleiotropic drug resistance by the J-protein and Hsp70-related proteins, Zuo1 and Ssz1
    • Eisenman H.C., and Craig E.A. Activation of pleiotropic drug resistance by the J-protein and Hsp70-related proteins, Zuo1 and Ssz1. Mol. Microbiol. 53 (2004) 335-344
    • (2004) Mol. Microbiol. , vol.53 , pp. 335-344
    • Eisenman, H.C.1    Craig, E.A.2
  • 24
    • 0025774660 scopus 로고
    • Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate
    • Fling M.E., Kopf J., Tamarkin A., Gorman J.A., Smith H.A., and Koltin Y. Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate. Mol. Gen. Genet. 227 (1991) 318-329
    • (1991) Mol. Gen. Genet. , vol.227 , pp. 318-329
    • Fling, M.E.1    Kopf, J.2    Tamarkin, A.3    Gorman, J.A.4    Smith, H.A.5    Koltin, Y.6
  • 26
    • 52649131910 scopus 로고    scopus 로고
    • Evidence for the bifunctional nature of mitochondrial phosphatidylserine decarboxylase: role in Pdr3-dependent retrograde regulation of PDR5 expression
    • Gulshan K., Schmidt J., Shahi P., and Moye-Rowley W.S. Evidence for the bifunctional nature of mitochondrial phosphatidylserine decarboxylase: role in Pdr3-dependent retrograde regulation of PDR5 expression. Mol. Cell. Biol. 28 (2008) 5851-5864
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 5851-5864
    • Gulshan, K.1    Schmidt, J.2    Shahi, P.3    Moye-Rowley, W.S.4
  • 27
    • 0031911786 scopus 로고    scopus 로고
    • Regulation of transcription factor Pdr1p function by a Hsp70 protein in Saccharomyces cerevisiae
    • Hallstrom T.C., Katzmann D.J., Torres R.J., Sharp W.J., and Moye-Rowley W.S. Regulation of transcription factor Pdr1p function by a Hsp70 protein in Saccharomyces cerevisiae. Mol. Cell. Biol. 18 (1998) 1147-1155
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1147-1155
    • Hallstrom, T.C.1    Katzmann, D.J.2    Torres, R.J.3    Sharp, W.J.4    Moye-Rowley, W.S.5
  • 28
    • 0035968336 scopus 로고    scopus 로고
    • Coordinate control of sphingolipid biosynthesis and multidrug resistance in Saccharomyces cerevisiae
    • Hallstrom T.C., Lambert L., Schorling S., Balzi E., Goffeau A., and Moye-Rowley W.S. Coordinate control of sphingolipid biosynthesis and multidrug resistance in Saccharomyces cerevisiae. J. Biol. Chem. 276 (2001) 23674-23680
    • (2001) J. Biol. Chem. , vol.276 , pp. 23674-23680
    • Hallstrom, T.C.1    Lambert, L.2    Schorling, S.3    Balzi, E.4    Goffeau, A.5    Moye-Rowley, W.S.6
  • 29
    • 0034057218 scopus 로고    scopus 로고
    • Hyperactive forms of the Pdr1p transcription factor fail to respond to positive regulation by the Hsp70 protein Pdr13p
    • Hallstrom T.C., and Moye-Rowley W.S. Hyperactive forms of the Pdr1p transcription factor fail to respond to positive regulation by the Hsp70 protein Pdr13p. Mol. Microbiol. 36 (2000) 402-413
    • (2000) Mol. Microbiol. , vol.36 , pp. 402-413
    • Hallstrom, T.C.1    Moye-Rowley, W.S.2
  • 30
    • 0034534975 scopus 로고    scopus 로고
    • Multiple signals from dysfunctional mitochondria activate the pleiotropic drug resistance pathway in Saccharomyces cerevisae
    • Hallstrom T.C., and Moye-Rowley W.S. Multiple signals from dysfunctional mitochondria activate the pleiotropic drug resistance pathway in Saccharomyces cerevisae. J. Biol. Chem. 275 (2000) 37347-37356
    • (2000) J. Biol. Chem. , vol.275 , pp. 37347-37356
    • Hallstrom, T.C.1    Moye-Rowley, W.S.2
  • 32
    • 0037248593 scopus 로고    scopus 로고
    • A conserved RING finger protein required for histone H2B monoubiquitination and cell size control
    • Hwang W.W., Venkatasubrahmanyam S., Ianculescu A.G., Tong A., Boone C., and Madhani H.D. A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. Mol. Cell. 11 (2003) 261-266
    • (2003) Mol. Cell. , vol.11 , pp. 261-266
    • Hwang, W.W.1    Venkatasubrahmanyam, S.2    Ianculescu, A.G.3    Tong, A.4    Boone, C.5    Madhani, H.D.6
  • 34
    • 39349086422 scopus 로고    scopus 로고
    • Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact
    • Kanafani Z., and Perfect J. Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact. Clin. Infect. Dis. 46 (2008) 120-128
    • (2008) Clin. Infect. Dis. , vol.46 , pp. 120-128
    • Kanafani, Z.1    Perfect, J.2
  • 35
    • 3342996550 scopus 로고    scopus 로고
    • Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters
    • Karababa M., Coste A.T., Rognon B., Bille J., and Sanglard D. Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters. Antimicrob. Agents Chemother. 48 (2004) 3064-3079
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3064-3079
    • Karababa, M.1    Coste, A.T.2    Rognon, B.3    Bille, J.4    Sanglard, D.5
  • 37
    • 0029836129 scopus 로고    scopus 로고
    • Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATP binding cassette transporter protein-encoding gene PDR5
    • Katzmann D.J., Hallstrom T.C., Mahe Y., and Moye-Rowley W.S. Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATP binding cassette transporter protein-encoding gene PDR5. J. Biol. Chem. 271 (1996) 23049-23054
    • (1996) J. Biol. Chem. , vol.271 , pp. 23049-23054
    • Katzmann, D.J.1    Hallstrom, T.C.2    Mahe, Y.3    Moye-Rowley, W.S.4
  • 38
    • 0028807740 scopus 로고
    • Expression of an ATP-binding cassette transporter encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae
    • Katzmann D.J., Hallstrom T.C., Voet M., Wysock W., Golin J., Volckaert G., and Moye-Rowley W.S. Expression of an ATP-binding cassette transporter encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae. Mol. Cell. Biol. 15 (1995) 6875-6883
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6875-6883
    • Katzmann, D.J.1    Hallstrom, T.C.2    Voet, M.3    Wysock, W.4    Golin, J.5    Volckaert, G.6    Moye-Rowley, W.S.7
  • 39
    • 2142647837 scopus 로고    scopus 로고
    • Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria
    • Kaur R., Castano I., and Cormack B.P. Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria. Antimicrob. Agents Chemother. 48 (2004) 1600-1613
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 1600-1613
    • Kaur, R.1    Castano, I.2    Cormack, B.P.3
  • 40
    • 0030768053 scopus 로고    scopus 로고
    • Plasma membrane translocation of fluorescent-labeled phosphatidylethanolamine is controlled by transcription regulators, PDR1 and PDR3
    • Kean L.S., Grant A.M., Angeletti C., Mahé Y., Kuchler K., Fuller R.S., and Nichols J.W. Plasma membrane translocation of fluorescent-labeled phosphatidylethanolamine is controlled by transcription regulators, PDR1 and PDR3. J. Cell Biol. 138 (1997) 255-270
    • (1997) J. Cell Biol. , vol.138 , pp. 255-270
    • Kean, L.S.1    Grant, A.M.2    Angeletti, C.3    Mahé, Y.4    Kuchler, K.5    Fuller, R.S.6    Nichols, J.W.7
  • 41
    • 6344269851 scopus 로고    scopus 로고
    • Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry
    • Kihara A., and Igarashi Y. Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry. Mol. Biol. Cell 15 (2004) 4949-4959
    • (2004) Mol. Biol. Cell , vol.15 , pp. 4949-4959
    • Kihara, A.1    Igarashi, Y.2
  • 42
    • 0036210292 scopus 로고    scopus 로고
    • Functional dissection of Pdr1p, a regulator of multidrug resistance in Saccharomyces cerevisiae
    • Kolaczkowska A., Kolaczkowski M., Delahodde A., and Goffeau A. Functional dissection of Pdr1p, a regulator of multidrug resistance in Saccharomyces cerevisiae. Mol. Genet. Genomics. 267 (2002) 96-106
    • (2002) Mol. Genet. Genomics. , vol.267 , pp. 96-106
    • Kolaczkowska, A.1    Kolaczkowski, M.2    Delahodde, A.3    Goffeau, A.4
  • 43
    • 40149095880 scopus 로고    scopus 로고
    • Compensatory activation of the mutidrug transporters Pdr5p, Snq2p and Yor1p by Pdr1p in Saccharomyces cerevisiae
    • Kolaczkowska A., Kolaczkowski M., Goffeau A., and Moye-Rowley W.S. Compensatory activation of the mutidrug transporters Pdr5p, Snq2p and Yor1p by Pdr1p in Saccharomyces cerevisiae. FEBS Lett. 582 (2008) 977-983
    • (2008) FEBS Lett. , vol.582 , pp. 977-983
    • Kolaczkowska, A.1    Kolaczkowski, M.2    Goffeau, A.3    Moye-Rowley, W.S.4
  • 44
    • 4143101352 scopus 로고    scopus 로고
    • Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae
    • Kolaczkowski M., Kolaczkowska A., Gaigg B., Schneiter R., and Moye-Rowley W.S. Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae. Eukaryot. Cell 3 (2004) 880-892
    • (2004) Eukaryot. Cell , vol.3 , pp. 880-892
    • Kolaczkowski, M.1    Kolaczkowska, A.2    Gaigg, B.3    Schneiter, R.4    Moye-Rowley, W.S.5
  • 46
    • 0037197022 scopus 로고    scopus 로고
    • Antifungal drug resistance of pathogenic fungi
    • Kontoyiannis D.P., and Lewis R.E. Antifungal drug resistance of pathogenic fungi. Lancet 359 (2002) 1135-1144
    • (2002) Lancet , vol.359 , pp. 1135-1144
    • Kontoyiannis, D.P.1    Lewis, R.E.2
  • 47
    • 0036207991 scopus 로고    scopus 로고
    • New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system
    • Le Crom S., Devaux F., Marc P., Zhang X., Moye-Rowley W.S., and Jacq C. New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system. Mol. Cell. Biol. 22 (2002) 2642-2649
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2642-2649
    • Le Crom, S.1    Devaux, F.2    Marc, P.3    Zhang, X.4    Moye-Rowley, W.S.5    Jacq, C.6
  • 48
    • 0141725524 scopus 로고    scopus 로고
    • The mediator coactivator complex: functional and physical roles in transcriptional regulation
    • Lewis B.A., and Reinberg D. The mediator coactivator complex: functional and physical roles in transcriptional regulation. J. Cell. Sci. 116 (2003) 3667-3675
    • (2003) J. Cell. Sci. , vol.116 , pp. 3667-3675
    • Lewis, B.A.1    Reinberg, D.2
  • 50
    • 0347993067 scopus 로고    scopus 로고
    • Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon
    • Lucau-Danila A., Delaveau T., Lelandais G., Devaux F., and Jacq C. Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. J. Biol. Chem. 278 (2003) 52641-52650
    • (2003) J. Biol. Chem. , vol.278 , pp. 52641-52650
    • Lucau-Danila, A.1    Delaveau, T.2    Lelandais, G.3    Devaux, F.4    Jacq, C.5
  • 51
    • 33749236250 scopus 로고    scopus 로고
    • A fungal family of transcriptional regulators: the zinc cluster proteins
    • MacPherson S., Larochelle M., and Turcotte B. A fungal family of transcriptional regulators: the zinc cluster proteins. Microbiol. Mol. Biol. Rev. 70 (2006) 583-604
    • (2006) Microbiol. Mol. Biol. Rev. , vol.70 , pp. 583-604
    • MacPherson, S.1    Larochelle, M.2    Turcotte, B.3
  • 52
    • 0036886570 scopus 로고    scopus 로고
    • The yeast zinc finger regulators Pdr1p and Pdr3p control pleiotropic drug resistance (PDR) as homo- and heterodimers in vivo
    • Mamnun Y.M., Pandjaitan R., Mahe Y., Delahodde A., and Kuchler K. The yeast zinc finger regulators Pdr1p and Pdr3p control pleiotropic drug resistance (PDR) as homo- and heterodimers in vivo. Mol. Microbiol. 46 (2002) 1429-1440
    • (2002) Mol. Microbiol. , vol.46 , pp. 1429-1440
    • Mamnun, Y.M.1    Pandjaitan, R.2    Mahe, Y.3    Delahodde, A.4    Kuchler, K.5
  • 53
    • 0034629140 scopus 로고    scopus 로고
    • Cloning of an alkaline ceramidase from Saccharomyces cerevisiae: an enzyme with reverse (CoA-independent) ceramide synthase activity
    • Mao C., Xu R., Bielawska A., and Obeid L.M. Cloning of an alkaline ceramidase from Saccharomyces cerevisiae: an enzyme with reverse (CoA-independent) ceramide synthase activity. J. Biol. Chem. 275 (2000) 6876-6884
    • (2000) J. Biol. Chem. , vol.275 , pp. 6876-6884
    • Mao, C.1    Xu, R.2    Bielawska, A.3    Obeid, L.M.4
  • 55
    • 0026602838 scopus 로고
    • Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5
    • Meyers S., Schauer W., Balzi E., Wagner M., Goffeau A., and Golin J. Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5. Curr. Genet. 21 (1992) 431-436
    • (1992) Curr. Genet. , vol.21 , pp. 431-436
    • Meyers, S.1    Schauer, W.2    Balzi, E.3    Wagner, M.4    Goffeau, A.5    Golin, J.6
  • 57
    • 47849102650 scopus 로고    scopus 로고
    • Outwitting multidrug resistance to antifungals
    • Monk B.C., and Goffeau A. Outwitting multidrug resistance to antifungals. Science 321 (2008) 367-369
    • (2008) Science , vol.321 , pp. 367-369
    • Monk, B.C.1    Goffeau, A.2
  • 58
    • 37349095258 scopus 로고    scopus 로고
    • The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans
    • Morschhauser J., Barker K.S., Liu T.T., Blab-Warmuth J., Homayouni R., and Rogers P.D. The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans. PLoS Pathog. 3 (2007) e164
    • (2007) PLoS Pathog. , vol.3
    • Morschhauser, J.1    Barker, K.S.2    Liu, T.T.3    Blab-Warmuth, J.4    Homayouni, R.5    Rogers, P.D.6
  • 59
    • 33745458264 scopus 로고    scopus 로고
    • Sec14p-like proteins regulate phosphoinositide homeostasis and intracellular protein and lipid trafficking in yeast
    • Mousley C.J., Tyeryar K.R., Ryan M.M., and Bankaitis V.A. Sec14p-like proteins regulate phosphoinositide homeostasis and intracellular protein and lipid trafficking in yeast. Biochem. Soc. Trans. 34 (2006) 21-49
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 21-49
    • Mousley, C.J.1    Tyeryar, K.R.2    Ryan, M.M.3    Bankaitis, V.A.4
  • 60
    • 4143087157 scopus 로고    scopus 로고
    • Transcriptional control of multidrug resistance in the yeast Saccharomyces
    • Moye-Rowley W.S. Transcriptional control of multidrug resistance in the yeast Saccharomyces. Prog. Nucleic Acids Res. Mol. Biol. 73 (2003) 251-279
    • (2003) Prog. Nucleic Acids Res. Mol. Biol. , vol.73 , pp. 251-279
    • Moye-Rowley, W.S.1
  • 61
    • 0030664378 scopus 로고    scopus 로고
    • Clustered amino acid substitutions in the yeast transcription regulator Pdr3p increase pleiotropic drug resistance and identify a new central regulatory domain
    • Nourani A., Papajova D., Delahodde A., Jacq C., and Subik J. Clustered amino acid substitutions in the yeast transcription regulator Pdr3p increase pleiotropic drug resistance and identify a new central regulatory domain. Mol. Gen. Genet. 256 (1997) 397-405
    • (1997) Mol. Gen. Genet. , vol.256 , pp. 397-405
    • Nourani, A.1    Papajova, D.2    Delahodde, A.3    Jacq, C.4    Subik, J.5
  • 62
    • 0036226237 scopus 로고    scopus 로고
    • Control of 26S proteasome expression by transcription factors regulating multidrug resistance in Saccharomyces cerevisiae
    • Owsianik G., Balzi E., and Ghislain M. Control of 26S proteasome expression by transcription factors regulating multidrug resistance in Saccharomyces cerevisiae. Mol. Microbiol. 43 (2002) 1295-1308
    • (2002) Mol. Microbiol. , vol.43 , pp. 1295-1308
    • Owsianik, G.1    Balzi, E.2    Ghislain, M.3
  • 63
    • 33646580767 scopus 로고    scopus 로고
    • Long chain base tolerance in Saccharomyces cerevisiae is induced by retrograde signals from the mitochondria
    • Panwar S.L., and Moye-Rowley W.S. Long chain base tolerance in Saccharomyces cerevisiae is induced by retrograde signals from the mitochondria. J. Biol. Chem. 281 (2006) 6376-6384
    • (2006) J. Biol. Chem. , vol.281 , pp. 6376-6384
    • Panwar, S.L.1    Moye-Rowley, W.S.2
  • 64
    • 0025760201 scopus 로고
    • The phosphoinositol sphingolipids of Saccharomyces cerevisiae are highly localized in the plasma membrane
    • Patton J.L., and Lester R.L. The phosphoinositol sphingolipids of Saccharomyces cerevisiae are highly localized in the plasma membrane. J. Bacteriol. 173 (1991) 3101-3108
    • (1991) J. Bacteriol. , vol.173 , pp. 3101-3108
    • Patton, J.L.1    Lester, R.L.2
  • 65
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of invasive candidiasis: a persistent public health problem
    • Pfaller M.A., and Diekema D.J. Epidemiology of invasive candidiasis: a persistent public health problem. Clin. Microbiol. Rev. 20 (2007) 133-163
    • (2007) Clin. Microbiol. Rev. , vol.20 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 66
    • 5444272819 scopus 로고    scopus 로고
    • Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus
    • Pfaller M.A., and Diekema D.J. Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus. J. Clin. Microbiol. 42 (2004) 4419-4431
    • (2004) J. Clin. Microbiol. , vol.42 , pp. 4419-4431
    • Pfaller, M.A.1    Diekema, D.J.2
  • 67
    • 1642378564 scopus 로고    scopus 로고
    • Tracking down lipid flippases and their biological functions
    • Pomorski T., Holthuis J.C., Herrmann A., and van Meer G. Tracking down lipid flippases and their biological functions. J. Cell. Sci. 117 (2004) 805-813
    • (2004) J. Cell. Sci. , vol.117 , pp. 805-813
    • Pomorski, T.1    Holthuis, J.C.2    Herrmann, A.3    van Meer, G.4
  • 68
    • 0037345029 scopus 로고    scopus 로고
    • Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis
    • Pomorski T., Lombardi R., Riezman H., Devaux P.F., van Meer G., and Holthuis J.C. Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis. Mol. Biol. Cell. 14 (2003) 1240-1254
    • (2003) Mol. Biol. Cell. , vol.14 , pp. 1240-1254
    • Pomorski, T.1    Lombardi, R.2    Riezman, H.3    Devaux, P.F.4    van Meer, G.5    Holthuis, J.C.6
  • 69
    • 0028928549 scopus 로고
    • Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals
    • Prasad R., Dewergifosse P., Goffeau A., and Balzi E. Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals. Curr. Genet. 27 (1995) 320-329
    • (1995) Curr. Genet. , vol.27 , pp. 320-329
    • Prasad, R.1    Dewergifosse, P.2    Goffeau, A.3    Balzi, E.4
  • 70
    • 24144451315 scopus 로고    scopus 로고
    • Changing patterns and trends in systemic fungal infections
    • Richardson M.D. Changing patterns and trends in systemic fungal infections. J. Antimicrob. Chemother. 56 Suppl. 1 (2005) i5-i11
    • (2005) J. Antimicrob. Chemother. , vol.56 , Issue.SUPPL. 1
    • Richardson, M.D.1
  • 71
    • 33745452678 scopus 로고    scopus 로고
    • Organization and functions of sphingolipid biosynthesis in yeast
    • Riezman H. Organization and functions of sphingolipid biosynthesis in yeast. Biochem. Soc. Trans. 34 (2006) 367-369
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 367-369
    • Riezman, H.1
  • 72
    • 0037378017 scopus 로고    scopus 로고
    • Genome-wide expression profile anlaysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates
    • Rogers P.D., and Barker K.S. Genome-wide expression profile anlaysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates. Antimicrob. Agents Chemother. 47 (2003) 1220-1227
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1220-1227
    • Rogers, P.D.1    Barker, K.S.2
  • 73
    • 0028307550 scopus 로고
    • Phosphatidylcholine translocase: a physiological role for the mdr2 gene
    • Ruetz S., and Gros P. Phosphatidylcholine translocase: a physiological role for the mdr2 gene. Cell 77 (1994) 1071-1081
    • (1994) Cell , vol.77 , pp. 1071-1081
    • Ruetz, S.1    Gros, P.2
  • 74
    • 0036232109 scopus 로고    scopus 로고
    • Homozygosity at the Candida albicans MTL locus associated with azole resistance
    • Rustad T.R., Stevens D.A., Pfaller M.A., and White T.C. Homozygosity at the Candida albicans MTL locus associated with azole resistance. Microbiology 148 (2002) 1061-1072
    • (2002) Microbiology , vol.148 , pp. 1061-1072
    • Rustad, T.R.1    Stevens, D.A.2    Pfaller, M.A.3    White, T.C.4
  • 77
    • 0035080323 scopus 로고    scopus 로고
    • Role of ATP-binding cassette transporter gene in high-frequency acquisition of resistance to azole antifungals in Candida glabrata
    • Sanglard D., Ischer F., and Bille J. Role of ATP-binding cassette transporter gene in high-frequency acquisition of resistance to azole antifungals in Candida glabrata. Antimicrob. Agents Chemother. 45 (2001) 1174-1183
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1174-1183
    • Sanglard, D.1    Ischer, F.2    Bille, J.3
  • 78
    • 0032734512 scopus 로고    scopus 로고
    • The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents
    • Sanglard D., Ischer F., Calabrese D., Majcherczyk P.A., and Bille J. The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents. Antimicrob. Agents Chemother. 43 (1999) 2753-2765
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 2753-2765
    • Sanglard, D.1    Ischer, F.2    Calabrese, D.3    Majcherczyk, P.A.4    Bille, J.5
  • 79
    • 0031047670 scopus 로고    scopus 로고
    • Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene
    • Sanglard D., Ischer F., Monod M., and Bille J. Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene. Microbiology 143 (1997) 405-416
    • (1997) Microbiology , vol.143 , pp. 405-416
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 80
    • 0036488166 scopus 로고    scopus 로고
    • Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences
    • Sanglard D., and Odds F.C. Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences. Lancet, Infect. Dis. 2 (2002) 73-85
    • (2002) Lancet, Infect. Dis. , vol.2 , pp. 73-85
    • Sanglard, D.1    Odds, F.C.2
  • 81
    • 34848840693 scopus 로고    scopus 로고
    • Negative transcriptional regulation of multidrug resistance gene expression by an Hsp70 protein
    • Shahi P., Gulshan K., and Moye-Rowley W.S. Negative transcriptional regulation of multidrug resistance gene expression by an Hsp70 protein. J. Biol. Chem. 282 (2007) 26822-26831
    • (2007) J. Biol. Chem. , vol.282 , pp. 26822-26831
    • Shahi, P.1    Gulshan, K.2    Moye-Rowley, W.S.3
  • 82
    • 35748935537 scopus 로고    scopus 로고
    • Recent advances and challenges in the treatment of invasive fungal infections
    • Shao P.L., Huang L.M., and Hsueh P.R. Recent advances and challenges in the treatment of invasive fungal infections. Int. J. Antimicrob. Agents 30 (2007) 487-495
    • (2007) Int. J. Antimicrob. Agents , vol.30 , pp. 487-495
    • Shao, P.L.1    Huang, L.M.2    Hsueh, P.R.3
  • 83
    • 0033637226 scopus 로고    scopus 로고
    • Isolation and molecular characterization of the carboxy-terminal pdr3 mutants in Saccharomyces cerevisiae
    • Simonics T., Kozovska Z., Michalkova-Papajova D., Delahodde A., Jacq C., and Subik J. Isolation and molecular characterization of the carboxy-terminal pdr3 mutants in Saccharomyces cerevisiae. Curr. Genet. 38 (2000) 248-255
    • (2000) Curr. Genet. , vol.38 , pp. 248-255
    • Simonics, T.1    Kozovska, Z.2    Michalkova-Papajova, D.3    Delahodde, A.4    Jacq, C.5    Subik, J.6
  • 84
    • 0032579259 scopus 로고    scopus 로고
    • Inhibition of amino acid transport by sphingoid long chain bases in Saccharomyces cerevisiae
    • Skrzypek M.S., Nagiec M.M., Lester R.L., and Dickson R.C. Inhibition of amino acid transport by sphingoid long chain bases in Saccharomyces cerevisiae. J. Biol. Chem. 273 (1998) 2824-2829
    • (1998) J. Biol. Chem. , vol.273 , pp. 2824-2829
    • Skrzypek, M.S.1    Nagiec, M.M.2    Lester, R.L.3    Dickson, R.C.4
  • 85
    • 0032902758 scopus 로고    scopus 로고
    • Isolation of a putative Candida albicans transcriptional regulator involved in pleiotropic drug resistance by functional complementation of a pdr1 pdr3 mutation in Saccharomyces cerevisiae
    • Talibi D., and Raymond M. Isolation of a putative Candida albicans transcriptional regulator involved in pleiotropic drug resistance by functional complementation of a pdr1 pdr3 mutation in Saccharomyces cerevisiae. J. Bacteriol. 181 (1999) 231-240
    • (1999) J. Bacteriol. , vol.181 , pp. 231-240
    • Talibi, D.1    Raymond, M.2
  • 87
    • 33645773419 scopus 로고    scopus 로고
    • Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants
    • Tsai H.F., Krol A.A., Sarti K.E., and Bennett J.E. Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants. Antimicrob. Agents Chemother. 50 (2006) 1384-1392
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1384-1392
    • Tsai, H.F.1    Krol, A.A.2    Sarti, K.E.3    Bennett, J.E.4
  • 88
    • 0000942202 scopus 로고    scopus 로고
    • PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs
    • van den Hazel H.B., Pichler H., do Valle Matta M.A., Leitner E., Goffeau A., and Daum G. PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs. J. Biol. Chem. 274 (1999) 1934-1941
    • (1999) J. Biol. Chem. , vol.274 , pp. 1934-1941
    • van den Hazel, H.B.1    Pichler, H.2    do Valle Matta, M.A.3    Leitner, E.4    Goffeau, A.5    Daum, G.6
  • 89
    • 33748042707 scopus 로고    scopus 로고
    • Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies
    • Vermitsky J.P., Earhart K.D., Smith W.L., Homayouni R., Edlind T.D., and Rogers P.D. Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies. Mol. Microbiol. 61 (2006) 704-722
    • (2006) Mol. Microbiol. , vol.61 , pp. 704-722
    • Vermitsky, J.P.1    Earhart, K.D.2    Smith, W.L.3    Homayouni, R.4    Edlind, T.D.5    Rogers, P.D.6
  • 90
    • 4644254793 scopus 로고    scopus 로고
    • Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor
    • Vermitsky J.P., and Edlind T.D. Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor. Antimicrob. Agents Chemother. 48 (2004) 3773-3781
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3773-3781
    • Vermitsky, J.P.1    Edlind, T.D.2
  • 91
    • 0035853037 scopus 로고    scopus 로고
    • RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit
    • Xie Y., and Varshavsky A. RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 3056-3061
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 3056-3061
    • Xie, Y.1    Varshavsky, A.2
  • 92
    • 0035937817 scopus 로고    scopus 로고
    • Cross-talk between transcriptional regulators of multidrug resistance in Saccharomyces cerevisiae
    • Zhang X., Cui Z., Miyakawa T., and Moye-Rowley W.S. Cross-talk between transcriptional regulators of multidrug resistance in Saccharomyces cerevisiae. J. Biol. Chem. 276 (2001) 8812-8819
    • (2001) J. Biol. Chem. , vol.276 , pp. 8812-8819
    • Zhang, X.1    Cui, Z.2    Miyakawa, T.3    Moye-Rowley, W.S.4
  • 93
    • 13244262884 scopus 로고    scopus 로고
    • Transcriptional regulation by Lge1p requires a function independent of its role in histone H2B ubiquitination
    • Zhang X., Kolaczkowska A., Devaux F., Panwar S.L., Hallstrom T.C., Jacq C., and Moye-Rowley W.S. Transcriptional regulation by Lge1p requires a function independent of its role in histone H2B ubiquitination. J. Biol. Chem. 280 (2005) 2759-2770
    • (2005) J. Biol. Chem. , vol.280 , pp. 2759-2770
    • Zhang, X.1    Kolaczkowska, A.2    Devaux, F.3    Panwar, S.L.4    Hallstrom, T.C.5    Jacq, C.6    Moye-Rowley, W.S.7
  • 94
    • 0035930633 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the Fo component of the mitochondrial ATPase
    • Zhang X., and Moye-Rowley W.S. Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the Fo component of the mitochondrial ATPase. J. Biol. Chem. 276 (2001) 47844-47852
    • (2001) J. Biol. Chem. , vol.276 , pp. 47844-47852
    • Zhang, X.1    Moye-Rowley, W.S.2


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