Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway

Apoptosis

Volumn 16, Issue 4, 2011, Pages 394-403

  Dong, Yinhui ^a   Yin, Shutao ^a   Li, Jinghua ^a   Jiang, Cheng ^b   Ye, Min ^c   Hu, Hongbo ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b UNIVERSITY OF MINNESOTA   (United States)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Apoptosis; Breast cancer cells; Bufadienolides; Mcl 1; TRAIL

Indexed keywords

BUFADIENOLIDE; BUFALIN; BUFOTALIN; CASPASE 3; CASPASE 8; CASPASE 9; ESTROGEN RECEPTOR ALPHA; FLUORESCEIN ISOTHIOCYANATE; GAMABUFOTALIN; LIPOCORTIN 5; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; STAT3 PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRIAL PERMEABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; BREAST NEOPLASMS; BUFANOLIDES; CASPASES; CELL LINE, TUMOR; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; ENZYME ACTIVATION; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 79955776401     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0573-5     Document Type: Article

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