Simultaneous determination of cytotoxic bufadienolides in the Chinese medicine ChanSu by high-performance liquid chromatography coupled with photodiode array and mass spectrometry detections

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 838, Issue 2, 2006, Pages 86-95

  Ye, Min ^a   Guo, Hui ^a   Guo, Hongzhu ^a   Han, Jian ^a   Guo, Dean ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Bufadienolide; ChanSu; Chinese medicine; Cytotoxicity; HPLC DAD APCI MS; Quality control

Indexed keywords

DRUG DOSAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETRY; ONCOLOGY; PHOTODIODES; QUALITY CONTROL; TOXICITY;

BUFADIENOLIDE; CHANSU; CHINESE MEDICINE; CYTOTOXICITY; HPLC/DAD/APCI-MS; QUALITY CONTROL;

MEDICINE;

BUFADIENOLIDE DERIVATIVE; CHANSU; METHANOL; UNCLASSIFIED DRUG; VENOM;

ANALYTIC METHOD; ARTICLE; CHINESE MEDICINE; CONCENTRATION (PARAMETERS); CYTOTOXICITY; DIODE; DRUG ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHOTODIODE ARRAY DETECTION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUALITY CONTROL; QUANTITATIVE ANALYSIS; TOAD; TRADITIONAL MEDICINE;

BUFANOLIDES; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MEDICINE, CHINESE TRADITIONAL; MODELS, CHEMICAL; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET;

ANURA;

EID: 33745387518     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.04.042     Document Type: Article

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