Spinal hyperpolarization-activated cyclic nucleotide-gated cation channels at primary afferent terminals contribute to chronic pain

Pain

Volumn 151, Issue 1, 2010, Pages 87-96

  Takasu, Keiko ^a   Ono, Hideki ^a   Tanabe, Mitsuo ^a,b  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

Hyperpolarization activated cation channels; Inflammatory pain; Neuropathic pain; Spinal slice; Synaptic transmission; ZD7288

Indexed keywords

4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; CYCLIC NUCLEOTIDE GATED CHANNEL; FORMALDEHYDE;

AFFERENT NERVE GROUP 1; ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH RECORDING; CHRONIC PAIN; CONTROLLED STUDY; DORSAL ROOT; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; HYPERALGESIA; HYPERPOLARIZATION; LICKING; MALE; MONOSYNAPTIC POTENTIAL; MOUSE; NERVE EXCITABILITY; NERVE FIBER C; NERVE LIGATION; NEUROMODULATION; NEUROPATHIC PAIN; NONHUMAN; PAIN ASSESSMENT; PATCH CLAMP; PERIPHERAL NERVE INJURY; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; SCIATIC NERVE; SPINAL CORD; SUBSTANTIA GELATINOSA; WHOLE CELL;

ANIMALS; CARDIOTONIC AGENTS; CHRONIC DISEASE; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; HYPERALGESIA; MALE; MEMBRANE POTENTIALS; MICE; MICE, NEUROLOGIC MUTANTS; NERVE FIBERS; PAIN MEASUREMENT; PATCH-CLAMP TECHNIQUES; PRESYNAPTIC TERMINALS; PYRIMIDINES; SCIATICA; SODIUM CHANNEL BLOCKERS; SPINAL CORD; TETRODOTOXIN;

EID: 79955771937     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2010.06.020     Document Type: Article

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