메뉴 건너뛰기




Volumn 19, Issue 2, 1999, Pages 859-867

Peripheral inflammation facilitates Aβ fiber-mediated synaptic input to the substantia gelatinosa of the adult rat spinal cord

Author keywords

Dorsal horn; Inflammation; Neural plasticity; Pain; Substantia gelatinosa; Synaptic transmission

Indexed keywords

FREUND ADJUVANT;

EID: 0033555793     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-02-00859.1999     Document Type: Article
Times cited : (156)

References (47)
  • 1
    • 0032055904 scopus 로고    scopus 로고
    • Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn
    • Baba H, Kohno T, Okamato M, Goldstein PA, Shimoji K, Yoshimura M (1998) Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn. J Physiol (Lond) 508:83-93.
    • (1998) J Physiol (Lond) , vol.508 , pp. 83-93
    • Baba, H.1    Kohno, T.2    Okamato, M.3    Goldstein, P.A.4    Shimoji, K.5    Yoshimura, M.6
  • 2
    • 0002762054 scopus 로고
    • Development and maturation of neurons in the substantia gclatinosa(SG) of the rat spinal cord
    • (Rowe M, Willis Jr WD, eds). New York: Wiley-Liss
    • Beal JA, Bicknell HR (1985) Development and maturation of neurons in the substantia gclatinosa(SG) of the rat spinal cord. In: Development, organization and processing in somatosensory pathway (Rowe M, Willis Jr WD, eds), pp 23-30. New York: Wiley-Liss.
    • (1985) Development, Organization and Processing in Somatosensory Pathway , pp. 23-30
    • Beal, J.A.1    Bicknell, H.R.2
  • 3
    • 0019160379 scopus 로고
    • Physiology and morphology of substantia gelatinosa neurons intracellularly stained with horseradish peroxidase
    • Bennett GJ, Abdelmoumene M, Hayashi H, Dubner R (1980) Physiology and morphology of substantia gelatinosa neurons intracellularly stained with horseradish peroxidase. J Comp Neurol 194:809-827.
    • (1980) J Comp Neurol , vol.194 , pp. 809-827
    • Bennett, G.J.1    Abdelmoumene, M.2    Hayashi, H.3    Dubner, R.4
  • 4
    • 0028173043 scopus 로고
    • The correlation between the distribution of the NK1 receptor and the action of tachykinin agonists in the dorsal horn of the rat indicates that substance P does not have a functional role on substantia gelatinosa (lamina II) neurons
    • Bleazard L, Hill RG, Morris R (1994) The correlation between the distribution of the NK1 receptor and the action of tachykinin agonists in the dorsal horn of the rat indicates that substance P does not have a functional role on substantia gelatinosa (lamina II) neurons. J Neurosci 14:7655-7664.
    • (1994) J Neurosci , vol.14 , pp. 7655-7664
    • Bleazard, L.1    Hill, R.G.2    Morris, R.3
  • 6
    • 0028036175 scopus 로고
    • Carragenan-induced inflammation of the hind foot provokes a rise of GABA-immunoreactive cells in the rat spinal cord that is prevented by peripheral neurectomy or neonatal capsaicin treatment
    • Castro-Lopes JM, Tavares I, Tolle TR, Coimbra A (1994) Carragenan-induced inflammation of the hind foot provokes a rise of GABA-immunoreactive cells in the rat spinal cord that is prevented by peripheral neurectomy or neonatal capsaicin treatment. Pain 56:193-201.
    • (1994) Pain , vol.56 , pp. 193-201
    • Castro-Lopes, J.M.1    Tavares, I.2    Tolle, T.R.3    Coimbra, A.4
  • 7
    • 0021895384 scopus 로고
    • Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurons
    • Harper AA, Lawson SN (1985) Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurons. J Physiol (Lond) 359:31-46.
    • (1985) J Physiol (Lond) , vol.359 , pp. 31-46
    • Harper, A.A.1    Lawson, S.N.2
  • 8
    • 0029945946 scopus 로고    scopus 로고
    • Changes in nociceptive reflex facilitation during carrageenan-induced arthritis
    • Herrero JF, Cervero F (1996a) Changes in nociceptive reflex facilitation during carrageenan-induced arthritis. Brain Res 717:62-68.
    • (1996) Brain Res , vol.717 , pp. 62-68
    • Herrero, J.F.1    Cervero, F.2
  • 9
    • 0029982084 scopus 로고    scopus 로고
    • Supraspinal influences on the facilitation of rat nociceptive reflexes induced by carrageenan monoarthritis
    • Herrero JF, Cervero F (1996b) Supraspinal influences on the facilitation of rat nociceptive reflexes induced by carrageenan monoarthritis. Neurosci Lett 209:21-24.
    • (1996) Neurosci Lett , vol.209 , pp. 21-24
    • Herrero, J.F.1    Cervero, F.2
  • 10
    • 0023277535 scopus 로고
    • Induction of c-fos-like protein in spinal cord neurones following sensory stimulation
    • Hunt SP, Pini A, Evan G (1987) Induction of c-fos-like protein in spinal cord neurones following sensory stimulation. Nature 328:632-634.
    • (1987) Nature , vol.328 , pp. 632-634
    • Hunt, S.P.1    Pini, A.2    Evan, G.3
  • 11
    • 0028235568 scopus 로고
    • Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain
    • Koltzenburg M, Torebjork HE, Wahren LK (1994) Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain. Brain 117:579-591.
    • (1994) Brain , vol.117 , pp. 579-591
    • Koltzenburg, M.1    Torebjork, H.E.2    Wahren, L.K.3
  • 12
    • 0017920987 scopus 로고
    • Excitation of marginal and substantia gelatinosa neurons in the primate spinal cord: Indications of their place in dorsal horn functional organization
    • Kumazawa T, Perl ER (1978) Excitation of marginal and substantia gelatinosa neurons in the primate spinal cord: indications of their place in dorsal horn functional organization. J Comp Neurol 177:417-434.
    • (1978) J Comp Neurol , vol.177 , pp. 417-434
    • Kumazawa, T.1    Perl, E.R.2
  • 13
    • 0001908159 scopus 로고
    • Inflammatory pain
    • (Wall PD, Melzack R, eds). Edinburgh: Churchill Livingstone
    • Levine JD, Taiwo YO (1994) Inflammatory pain. In: Textbook of pain (Wall PD, Melzack R, eds), pp 45-56. Edinburgh: Churchill Livingstone.
    • (1994) Textbook of Pain , pp. 45-56
    • Levine, J.D.1    Taiwo, Y.O.2
  • 14
    • 0018763580 scopus 로고
    • Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn
    • Light AR, Trevino DL, Perl ER (1979) Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn. J Comp Neurol 186:151-172.
    • (1979) J Comp Neurol , vol.186 , pp. 151-172
    • Light, A.R.1    Trevino, D.L.2    Perl, E.R.3
  • 15
    • 0020052002 scopus 로고
    • Primary afferent units from the hairy skin of the rat hind limb
    • Lynn B, Carpenter SE (1982) Primary afferent units from the hairy skin of the rat hind limb. Brain Res 238:29-43.
    • (1982) Brain Res , vol.238 , pp. 29-43
    • Lynn, B.1    Carpenter, S.E.2
  • 16
    • 0030247053 scopus 로고    scopus 로고
    • Progressive tactile hypersensitivity: An inflammation-induced incremental increase in the excitability of the spinal cord
    • Ma Q-P, Woolf CJ (1996a) Progressive tactile hypersensitivity: an inflammation-induced incremental increase in the excitability of the spinal cord. Pain 67:97-106.
    • (1996) Pain , vol.67 , pp. 97-106
    • Ma, Q.-P.1    Woolf, C.J.2
  • 17
    • 0030273206 scopus 로고    scopus 로고
    • Basal and touch-evoked fos-like immunoreactivity during experimental inflammation in the rat
    • Ma Q-P, Woolf CJ (1996b) Basal and touch-evoked fos-like immunoreactivity during experimental inflammation in the rat. Pain 67:307-316.
    • (1996) Pain , vol.67 , pp. 307-316
    • Ma, Q.-P.1    Woolf, C.J.2
  • 18
    • 0027976556 scopus 로고
    • NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociception
    • McCarson KE, Krause JE (1994) NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociception. J Neurosci 14:712-720.
    • (1994) J Neurosci , vol.14 , pp. 712-720
    • McCarson, K.E.1    Krause, J.E.2
  • 19
    • 0029954092 scopus 로고    scopus 로고
    • Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurones
    • Neumann S, Doubell TP, Leslie TA, Woolf CJ (1996) Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurones. Nature 384:360-364.
    • (1996) Nature , vol.384 , pp. 360-364
    • Neumann, S.1    Doubell, T.P.2    Leslie, T.A.3    Woolf, C.J.4
  • 20
    • 0025853449 scopus 로고
    • Dynorphin expression and fos-like immunoreactivity following inflammation induced hyperalgesia are co-localized in spinal cord neurons
    • Noguchi K, Kowalski K, Traub R, Solodkin A, Iadarola MJ, Ruda MA (1991) Dynorphin expression and fos-like immunoreactivity following inflammation induced hyperalgesia are co-localized in spinal cord neurons. Brain Res Mol Brain Res 10:227-233.
    • (1991) Brain Res Mol Brain Res , vol.10 , pp. 227-233
    • Noguchi, K.1    Kowalski, K.2    Traub, R.3    Solodkin, A.4    Iadarola, M.J.5    Ruda, M.A.6
  • 21
    • 0012090497 scopus 로고    scopus 로고
    • Synaptic plasticity of substantia gelatinosa neurons in the chronic pain model rat
    • Okamoto M, Yoshimura M, Baba H, Higashi H, Shimoji K (1996) Synaptic plasticity of substantia gelatinosa neurons in the chronic pain model rat. Jpn J Physiol 46:8136.
    • (1996) Jpn J Physiol , vol.46 , pp. 8136
    • Okamoto, M.1    Yoshimura, M.2    Baba, H.3    Higashi, H.4    Shimoji, K.5
  • 22
    • 0025137135 scopus 로고
    • Systemic morphine suppresses noxious stimulus-evoked fos protein-like immunoreactivity in the rat spinal cord
    • Presley RW, Menetrey D, Levine JD, Bausbaum AI (1990) Systemic morphine suppresses noxious stimulus-evoked fos protein-like immunoreactivity in the rat spinal cord. J Neurosci 10:323-335.
    • (1990) J Neurosci , vol.10 , pp. 323-335
    • Presley, R.W.1    Menetrey, D.2    Levine, J.D.3    Bausbaum, A.I.4
  • 23
    • 0028973160 scopus 로고
    • k-opioid receptor agonists modulate excitatory transmission in substantia gelatinosa neurons of the rat spinal cord
    • Randic M, Cheng G, Kojic L (1995) k-opioid receptor agonists modulate excitatory transmission in substantia gelatinosa neurons of the rat spinal cord. J Neurosci 15:6809-6826.
    • (1995) J Neurosci , vol.15 , pp. 6809-6826
    • Randic, M.1    Cheng, G.2    Kojic, L.3
  • 24
    • 0027501057 scopus 로고
    • NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw
    • Ren K, Dubner R (1993) NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw. Neurosci Lett 163:22-26.
    • (1993) Neurosci Lett , vol.163 , pp. 22-26
    • Ren, K.1    Dubner, R.2
  • 25
    • 0026709480 scopus 로고
    • The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioural hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation
    • Ren K, Hylden JLK, Williams GM, Ruda MA, Dubner R (1992a) The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioural hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain 50:331-344.
    • (1992) Pain , vol.50 , pp. 331-344
    • Ren, K.1    Hylden, J.L.K.2    Williams, G.M.3    Ruda, M.A.4    Dubner, R.5
  • 26
    • 0026669928 scopus 로고
    • The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats
    • Ren K, Williams GM, Hylden JLK, Ruda MA, Dubner R (1992b) The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats. Eur J Pharmacol 219:235-243.
    • (1992) Eur J Pharmacol , vol.219 , pp. 235-243
    • Ren, K.1    Williams, G.M.2    Hylden, J.L.K.3    Ruda, M.A.4    Dubner, R.5
  • 27
    • 0038094464 scopus 로고
    • In situ hybridization histochemistry and immunocytochemistry reveal and increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia
    • HI
    • Ruda MA, Iadarola MJ, Cohen LV, Young WS, HI (1988) In situ hybridization histochemistry and immunocytochemistry reveal and increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia. Proc Natl Acad Sci USA 85:622-626.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 622-626
    • Ruda, M.A.1    Iadarola, M.J.2    Cohen, L.V.3    Young, W.S.4
  • 28
    • 0343035586 scopus 로고    scopus 로고
    • Low-frequency stimulation of afferent Aδ-fibers induces long term depression at primary afferent synapses with substantia gelatinosa neurons in the rat
    • Sandkuhler J, Chen JG, Cheng G, Randic M (1997) Low-frequency stimulation of afferent Aδ-fibers induces long term depression at primary afferent synapses with substantia gelatinosa neurons in the rat. J Neurosci 17:6483-6491.
    • (1997) J Neurosci , vol.17 , pp. 6483-6491
    • Sandkuhler, J.1    Chen, J.G.2    Cheng, G.3    Randic, M.4
  • 29
    • 0027246636 scopus 로고
    • Inflammation-induced upregulation of NK1 receptor mRNA in dorsal horn neurones
    • Schafer MK, Nohr D, Krause JE, Weihe E (1993) Inflammation-induced upregulation of NK1 receptor mRNA in dorsal horn neurones. NeuroReport 4:1007-1010.
    • (1993) NeuroReport , vol.4 , pp. 1007-1010
    • Schafer, M.K.1    Nohr, D.2    Krause, J.E.3    Weihe, E.4
  • 30
    • 0024523888 scopus 로고
    • Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicin
    • Simone DA, Baumann TK, Collins JG, LaMotte RH (1989) Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicin. Brain Res 486:185-189.
    • (1989) Brain Res , vol.486 , pp. 185-189
    • Simone, D.A.1    Baumann, T.K.2    Collins, J.G.3    LaMotte, R.H.4
  • 31
    • 0024153212 scopus 로고
    • Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: Alterations in behavior and nociceptive thresholds
    • Stein C, Millan MJ, Herz A (1988) Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds. Pharmacol Biochem Behav 31:445-451.
    • (1988) Pharmacol Biochem Behav , vol.31 , pp. 445-451
    • Stein, C.1    Millan, M.J.2    Herz, A.3
  • 32
    • 0025354044 scopus 로고
    • Activity-dependent changes in rat ventral horn neurones in vitro: Summation of prolonged afferent evoked postsynaptic depolarizations produce a D-APV sensitive windup
    • Thompson SW, King AE, Woolf CJ (1990) Activity-dependent changes in rat ventral horn neurones in vitro: summation of prolonged afferent evoked postsynaptic depolarizations produce a D-APV sensitive windup. Eur J Neurosci 2:638-649.
    • (1990) Eur J Neurosci , vol.2 , pp. 638-649
    • Thompson, S.W.1    King, A.E.2    Woolf, C.J.3
  • 33
    • 0027175088 scopus 로고
    • Small caliber afferents produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A fibres in the neonatal rat spinal cord in vitro
    • Thompson SW, Woolf CJ, Sivilotti LG (1993) Small caliber afferents produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A fibres in the neonatal rat spinal cord in vitro. J Neurophysiol 69:2116-2128.
    • (1993) J Neurophysiol , vol.69 , pp. 2116-2128
    • Thompson, S.W.1    Woolf, C.J.2    Sivilotti, L.G.3
  • 34
    • 0028301271 scopus 로고
    • Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- and C-fiber mediated responses in the rat spinal cord in vitro
    • Thompson SW, Dray A, Urban L (1994) Injury-induced plasticity of spinal reflex activity: NK1 neurokinin receptor activation and enhanced A- and C-fiber mediated responses in the rat spinal cord in vitro. J Neurosci 14:3672-3687.
    • (1994) J Neurosci , vol.14 , pp. 3672-3687
    • Thompson, S.W.1    Dray, A.2    Urban, L.3
  • 35
    • 0026534771 scopus 로고
    • Central changes in processing of mechanoreceptor input in capsaicin-induced sensory hyperalgesia in humans
    • Torebjork HE, Lundberg LER, LaMotte RH (1992) Central changes in processing of mechanoreceptor input in capsaicin-induced sensory hyperalgesia in humans. J Physiol (Lond) 448:765-780.
    • (1992) J Physiol (Lond) , vol.448 , pp. 765-780
    • Torebjork, H.E.1    Lundberg, L.E.R.2    LaMotte, R.H.3
  • 36
    • 0029764479 scopus 로고    scopus 로고
    • Electrophysiological properties of neurons in intact rat dorsal root ganglia classified by conduction velocity and action potential duration
    • Villiere V, McLachlan EM (1996) Electrophysiological properties of neurons in intact rat dorsal root ganglia classified by conduction velocity and action potential duration. J Neurophysiol 76:1924-1941.
    • (1996) J Neurophysiol , vol.76 , pp. 1924-1941
    • Villiere, V.1    McLachlan, E.M.2
  • 38
    • 0021014399 scopus 로고
    • Evidence for a central component of post-injury pain hypersensitivity
    • Woolf CJ (1983) Evidence for a central component of post-injury pain hypersensitivity. Nature 306:686-688.
    • (1983) Nature , vol.306 , pp. 686-688
    • Woolf, C.J.1
  • 39
    • 0023254828 scopus 로고
    • Central terminations of cutaneous mechanoreceptive afferents in the rat lumbar spinal cord
    • Woolf CJ (1987) Central terminations of cutaneous mechanoreceptive afferents in the rat lumbar spinal cord. J Comp Neurol 261:105-119.
    • (1987) J Comp Neurol , vol.261 , pp. 105-119
    • Woolf, C.J.1
  • 40
    • 0021016561 scopus 로고
    • The properties of neurons recorded in the superficial dorsal horn of the rat spinal cord
    • Woolf CJ, Fitzgerald M (1983) The properties of neurons recorded in the superficial dorsal horn of the rat spinal cord. J Comp Neurol 221:313-328.
    • (1983) J Comp Neurol , vol.221 , pp. 313-328
    • Woolf, C.J.1    Fitzgerald, M.2
  • 41
    • 0025471841 scopus 로고
    • Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord
    • Woolf CJ, King AE (1990) Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord. J Neurosci 10:2717-2726.
    • (1990) J Neurosci , vol.10 , pp. 2717-2726
    • Woolf, C.J.1    King, A.E.2
  • 42
    • 0026555273 scopus 로고
    • Peripheral nerve injury triggers central sprouting of myelinated afferents
    • Woolf CJ, Shortland P, Coggeshall RE (1992) Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature 355:75-77.
    • (1992) Nature , vol.355 , pp. 75-77
    • Woolf, C.J.1    Shortland, P.2    Coggeshall, R.E.3
  • 43
    • 0028128856 scopus 로고
    • Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurons following chemosensitive primary afferent activation
    • Woolf CJ, Shortland P, Sivilotti LG (1994) Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurons following chemosensitive primary afferent activation. Pain 58:141-155.
    • (1994) Pain , vol.58 , pp. 141-155
    • Woolf, C.J.1    Shortland, P.2    Sivilotti, L.G.3
  • 44
    • 0024356486 scopus 로고
    • Primary afferent evoked synaptic responses and slow potential generation in rat substantia gelatinosa neurons in vitro
    • Yoshimura M, Jessell TM (1989) Primary afferent evoked synaptic responses and slow potential generation in rat substantia gelatinosa neurons in vitro. J Neurophysiol 62:96-108.
    • (1989) J Neurophysiol , vol.62 , pp. 96-108
    • Yoshimura, M.1    Jessell, T.M.2
  • 45
    • 0025087072 scopus 로고
    • Amino acid-mediated EPSPs at primary afferent synapses with substantia gelatinosa neurones in the rat spinal cord
    • Yoshimura M, Jessell TM (1990) Amino acid-mediated EPSPs at primary afferent synapses with substantia gelatinosa neurones in the rat spinal cord. J Physiol (Lond) 430:315-335.
    • (1990) J Physiol (Lond) , vol.430 , pp. 315-335
    • Yoshimura, M.1    Jessell, T.M.2
  • 46
    • 0027416836 scopus 로고
    • Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: Pharmacological properties of synaptic currents
    • Yoshimura M, Nishi S (1993) Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: pharmacological properties of synaptic currents. Neuroscience 53:519-526.
    • (1993) Neuroscience , vol.53 , pp. 519-526
    • Yoshimura, M.1    Nishi, S.2
  • 47
    • 0028842988 scopus 로고
    • Primary afferent-evoked glycine- and GABA-mediated IPSPs in substantia gelatinosa neurones in the rat spinal cord in vitro
    • Yoshimura M, Nishi S (1995) Primary afferent-evoked glycine- and GABA-mediated IPSPs in substantia gelatinosa neurones in the rat spinal cord in vitro. J Physiol (Lond) 482:29-38.
    • (1995) J Physiol (Lond) , vol.482 , pp. 29-38
    • Yoshimura, M.1    Nishi, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.