Quantitative structure activity relationship studies on a novel indolediones as long chain fatty acid elongase 6 (ELOVL6) inhibitors

Letters in Drug Design and Discovery

Volumn 8, Issue 5, 2011, Pages 422-429

  Zheng, Junxia ^a   Wu, Zhiwei ^b   Dai, Mibei ^b   Xu, Zhihui ^b   Li, Xiaomei ^b   Zhu, Shanshan ^b   Lin, Chuyun ^b   Hu, Peijian ^b   Zhang, Luo ^b   Huang, Huarong ^a   Zhao, Suqing ^a   Zhang, Kun ^a   Sun, Pinghua ^b  

^a GUANGDONG UNIVERSITY OF TECHNOLOGY   (China)

^b JINAN UNIVERSITY   (China)

Author keywords

CoMFA; CoMSIA; Diabetes; ELOVL6; Indolediones; QSAR

Indexed keywords

ENZYME INHIBITOR; INDOLE DERIVATIVE; INDOLEDIONE DERIVATIVE; LONG CHAIN FATTY ACID ELONGASE 6; LONG CHAIN FATTY ACID ELONGASE 6 INHIBITOR; UNCLASSIFIED DRUG; VERY LONG CHAIN FATTY ACID;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; HYDROPHOBICITY; IC 50; PRIORITY JOURNAL; STATIC ELECTRICITY; STEREOSPECIFICITY;

EID: 79955758738     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018011795514168     Document Type: Article

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