3D-QSAR studies on quinazoline antifolate thymidylate synthase inhibitors by CoMFA and CoMSIA models

European Journal of Medicinal Chemistry

Volumn 45, Issue 4, 2010, Pages 1560-1571

  Srivastava, Vivek ^a,c   Gupta, S P ^a   Siddiqi, M I ^b   Mishra, B N ^c  

^a MEERUT INSTITUTE OF ENGINEERING AND TECHNOLOGY   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

^c INSTITUTE OF ENGINEERING AND TECHNOLOGY   (India)

Author keywords

CoMFA; CoMSIA; QSAR; Quinazolines; Thymidylate synthase inhibitors

Indexed keywords

FOLIC ACID ANTAGONIST; QUINAZOLINE DERIVATIVE; THYMIDYLATE SYNTHASE INHIBITOR;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ACTIVITY RELATION;

FOLIC ACID ANTAGONISTS; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINAZOLINES; THYMIDYLATE SYNTHASE;

EID: 77349111693     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.12.065     Document Type: Article

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