EMILIN2 (Elastin microfibril interface located protein), potential modifier of thrombosis

Thrombosis Journal

Volumn 9, Issue , 2011, Pages

  Sa, Qila ^a   Hoover Plow, Jane L ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTIN MICROFIBRIL INTERFACE LOCATED PROTEIN 2; GLYCOPROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BONE MARROW; CAROTID ARTERY; ENDOTHELIUM CELL; FIBROBLAST; HEART; IMMUNOHISTOCHEMISTRY; LUNG; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; THROMBOCYTE AGGREGATION; THROMBOSIS; THROMBUS;

EID: 79955754383     PISSN: None     EISSN: 14779560     Source Type: Journal    
DOI: 10.1186/1477-9560-9-9     Document Type: Article

References (50)

1. Ross R. Atherosclerosis - An inflammatory disease. N Engl J Med 1999, 340:115-26. 10.1056/NEJM199901143400207, 9887164.
2. Voetsch B, Loscalzo J. Genetic determinants of arterial thrombosis. Arterioscler Thromb Vasc Biol 2004, 24:216-229.
3. Humphries SE, Lane A, Dawson S, Green FR. The study of gene-environment interactions that influence thrombosis and fibrinolysis. Genetic variation at the loci for factor VII and plasminogen activator inhibitor-1. Arch Pathol Lab Med 1992, 116:1322-1329.
4. Marenberg ME, Risch N, Berman LF, Floderus B, de Faire U. Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med 1994, 330:1041-1046. 10.1056/NEJM199404143301503, 8127331.
5. Lusis AJ, Fogelman AM, Fonarow GC. Genetic basis of atherosclerosis: Part II. Clinical implications. Circulation 2004, 110:2066-2071. 10.1161/01.CIR.0000143098.98869.F8, 15466657.
6. Westrick RJ, Eitzman DT. Plasminogen activator inhibitor-1 in vascular thrombosis. Curr Drug Targets 2007, 8:966-1002.
7. Cui J, Eitzman DT, Westrick RJ, Christie PD, Xu ZJ, Yang AY, Purkayastha AA, Yang TL, Metz AL, Gallagher KP, Tyson JA, Rosenberg RD, Ginsburg D. Spontaneous thrombosis in mice carrying the factor V Leiden mutation. Blood 2000, 96:4222-4226.
8. D'Andrea D, Ravera M, Golino P, Rosica A, De Felice M, Ragni M, Cirillo P, Vigorito F, Corcione N, Tommasini P, Gargiulo A, Piro O, Calabro P, Chiariello M. Induction of tissue factor in the arterial wall during recurrent thrombus formation. Arterioscler Thromb Vasc Biol 2003, 23:1684-1689. 10.1161/01.ATV.0000087034.22709.5F, 12869352.
9. Eren M, Painter CA, Atkinson JB, Declerck PJ, Vaughan DE. Age-dependent spontaneous coronary arterial thrombosis in transgenic mice that express a stable form of human plasminogen activiator inhibitor-1. Circulation 2002, 106:491-496. 10.1161/01.CIR.0000023186.60090.FB, 12135951.
10. C Li TT, Larrucea S, Souza S, Leal SM, Lopez JA, Rubin EM, Nieswandt B, Bray PF. Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered platelet responses to collagen. Blood 2004, 103:3396-3402. 10.1182/blood-2003-10-3721, 14739220.
11. Sha J, McCullough B, Hart E, Nassir F, Davidson NO, Hoover-Plow J. Apo(a) promotes thrombosis in a vascular injury model by a mechanism independent of plasminogen. J Thromb Haemost 2005, 3:2281-2289. 10.1111/j.1538-7836.2005.01540.x, 16150044.
12. Doliana R, Bot S, Mungiguerra G, Canton A, Cilli SP, Colombatti A. Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily. J Biol Chem 2001, 276(15):12003-12011. 10.1074/jbc.M011591200, 11278945.
13. Colombatti A, Doliana R, Bot S, Canton A, Mongiat M, Mungiguerra G, Paron-Cilli S, Spessotto P. The EMILIN protein family. Matrix Biol 2000, 19:289-301. 10.1016/S0945-053X(00)00074-3, 10963989.
14. Tom TY, Hu T, Arterburn M, Boyle B, Bright JM, Palencia S, Emtage PC, Funk WD. The complete complement of C1q-domain-containing proteins in Homo sapiens. Genomics 2005, 86:100-111. 10.1016/j.ygeno.2005.03.001, 15953544.
15. Hayward CP, Hassell JA, Denomme GA, Rachubinski RA, Brown C, Kelton JG. The cDNA sequence of human endothelial cell multimerin. A unique protein with RGDS, coiled-coil, and epidermal growth factor-like domains and a carboxyl terminus similar to the globular domain of complement C1q and collagens type VIII and X. J Biol Chem 1995, 270:18246-18251. 10.1074/jbc.270.31.18246, 7629143.
16. Zanetti M, Braghetta P, Sabatelli P, Mura I, Doliana R, Colombatti A, Volpin D, Bonaldo P, Bressan GM. EMILIN-1 deficiency induces elastogenesis and vascular cell defects. Mol Cell Biol 2004, 24:638-650. 10.1128/MCB.24.2.638-650.2004, 343785, 14701737.
17. Danussi C, Spessotto P, Petrucco A, Wassermann B, Sabatelli P, Montesi M, Doliana R, Bressan GM, Colombatti A. Emilin1 deficiency causes structural and functional defects of lymphatic vasculature. Mol Cell Biol 2008, 28:4026-4039. 10.1128/MCB.02062-07, 2423131, 18411305.
18. Spessotto P, Cervi M, Mucignat MT, Mungiguerra G, Sartoretto I, Doliana R, Colombatti A. beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain. J Biol Chem 2003, 278:6160-6167. 10.1074/jbc.M208322200, 12456677.
19. Hayward CP, Fuller N, Zheng S, Adam F, Jeimy SB, Horsewood I, Quinn-Allen MA, Kane WH. Human platelets contain forms of factor V in disulfide-linkage with multimerin. Thromb Haemost 2004, 92:1349-1357.
20. Mann KG, Kalafatis M. Factor V: a combination of Dr Jekyll and Mr Hyde. Blood 2003, 101:20-30. 10.1182/blood-2002-01-0290, 12393635.
21. Braghetta P, Ferrari A, De GP, Zanetti M, Volpin D, Bonaldo P, Bressan GM. Overlapping, complementary and site-specific expression pattern of genes of the EMILIN/Multimerin family. Matrix Biol 2004, 22:549-56. 10.1016/j.matbio.2003.10.005, 14996434.
22. Leimeister C, Steidl C, Schumacher N, Erhard S, Gessler M. Developmental expression and biochemical characterization of Emu family members. Dev Biol 2002, 249:204-218. 10.1006/dbio.2002.0764, 12221002.
23. Milanetto M, Tiso N, Braghetta P, Volpin D, Argenton F, Bonaldo P. Emilin genes are duplicated and dynamically expressed during zebrafish embryonic development. Dev Dyn 2008, 237:222-232. 10.1002/dvdy.21402, 18095348.
24. Kielty CM, Sherratt MJ, Shuttleworth CA. Elastic fibres. J Cell Sci 2002, 115:2817-2828.
25. Tran H, Tanaka A, Litvinovich SV, Medved LV, Haudenschild CC, Argraves WS. The interaction of fibulin-1 with fibrinogen. A potential role in hemostasis and thrombosis. J Biol Chem 1995, 270:19458-19464. 10.1074/jbc.270.33.19458, 7642629.
26. McLaughlin PJ, Chen Q, Horiguchi M, Starcher BC, Stanton JB, Broekelmann TJ, Marmorstein AD, McKay B, Mecham R, Nakamura T, Marmorstein LY. Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice. Mol Cell Biol 2006, 26:1700-1709. 10.1128/MCB.26.5.1700-1709.2006, 1430262, 16478991.
27. Hanada K, Vermeij M, Garinis GA, de Waard MC, Kunen MG, Myers L, Maas A, Duncker DJ, Meijers C, Dietz HC, Kanaar R, Essers J. Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice. Circ Res 2007, 100:738-746. 10.1161/01.RES.0000260181.19449.95, 17293478.
28. Hoover-Plow J, Shchurin A, Hart E, Sha J, Hill AE, Singer JB, Nadeau JH. Genetic background determines response to hemostasis and thrombosis. BMC Blood Disord 2006, 6:6. 10.1186/1471-2326-6-6, 1617083, 17022820.
29. Werneck CC, Vicente CP, Weinberg JS, Shifren A, Pierce RA, Broekelmann TJ, Tollefsen DM, Mecham RP. Mice lacking the extracellular matrix protein MAGP1 display delayed thrombotic occlusion following vessel injury. Blood 2008, 111:4137-4144. 10.1182/blood-2007-07-101733, 2288724, 18281502.
30. Robinson PN, Godfrey M. The molecular genetics of Marfan syndrome and related microfibrillopathies. J Med Genet 2000, 37:9-25. 10.1136/jmg.37.1.9, 1734449, 10633129.
31. Hirai M, Ohbayashi T, Horiguchi M, Okawa K, Hagiwara A, Chien KR, Kita T, Nakamura T. Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo. J Cell Biol 2007, 176:1061-1071. 10.1083/jcb.200611026, 2064089, 17371835.
32. Amma LL, Goodyear R, Faris JS, Jones I, Ng L, Richardson G, Forrest D. An emilin family extracellular matrix protein identified in the cochlear basilar membrane. Mol Cell Neurosci 2003, 23:460-472. 10.1016/S1044-7431(03)00075-7, 12837629.
33. Campbell CD, Kirby A, Nemesh J, Daly MJ, Hirschhorn JN. A survey of allelic imbalance in F1 mice. Genome Res 2008, 18:555-563. 10.1101/gr.068692.107, 2279243, 18256236.
34. VanHoof D, Dormeyer W, Braam SR, Passier R, Monshouwer-Kloots J, Ward-van O, Heck AJR, Krijgsveld J, Mummery CL. Identification of cell surface proteins for antibody-based selection of human embryonic stem cell-dervived cardiomyocytes. J Proteome Res 2010, 9:1610-1618. 10.1021/pr901138a, 20088484.
35. Remme CA, Scicluna BP, Verkerk AO, Amin AS, van Brunschot S, Beekman L, Deneer VH, Chevalier C, Oyama F, Miyazaki H, Nukina N, Wilders R, Escande D, Houlgatte R, Wilde AA, Tan HL, Veldkamp MW, de Bakker JM, Bezzina CR. Genetically Determined Differences in Sodium Current Characteristics Modulate Conduction Disease Severity in Mice With Cardiac Sodium Channelopathy. Circ Res 2009, 104:1283-1292. 10.1161/CIRCRESAHA.109.194423, 19407241.
36. Omenn GS, States DJ, Adamski M, Blackwell TW, Menon R, Hermjakob H, Apweiler R, Haab BB, Simpson RJ, Eddes JS, Kapp EA, Moritz RL, Chan DW, Rai AJ, Admon A, Aebersold R, Eng J, Hancock WS, Hefta SA, Meyer H, Paik YK, Yoo JS, Ping P, Pounds J, Adkins J, Qian X, Wang R, Wasinger V, Wu CY, Zhao X, Zeng R, Archakov A, Tsugita A, Beer I, Pandey A, Pisano M, Andrews P, Tammen H, Speicher DW, Hanash SM. Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. Proteomics 2005, 5:3226-3245. 10.1002/pmic.200500358, 16104056.
37. Cho CK, Shan SJ, Winsor EJ, Diamandis EP. Proteomics analysis of human amniotic fluid. Mol Cell Proteomics 2007, 6:1406-1415. 10.1074/mcp.M700090-MCP200, 17495049.
38. Pilch B, Mann M. Large-scale and high-confidence proteomic analysis of human seminal plasma. Genome Biol 2006, 7:R40. 10.1186/gb-2006-7-5-r40, 1779515, 16709260.
39. Cano L, Arkfeld DG. Targeted synovial fluid proteomics for biomarker discovery in rheumatoid arthritis. Clin Proteom 2010, 5:75-102.
40. Sasahara A, Kasuya H, Akagawa H, Ujiie H, Kubo O, Sasaki T, Onda H, Sakamoto Y, Krischek B, Hori T, Inoue I. Increased expression of ephrin A1 in brain arteriovenous malformation: DNA microarray analysis. Neurosurg Rev 2007, 30:299-305. 10.1007/s10143-007-0087-3, 17576607.
41. Drewniak A, van Raam BJ, Geissler J, Tool AT, Mook OR, van den Berg TK, Baas F, Kuijpers TW. Changes in gene expression of granulocytes during in vivo granulocyte colony-stimulating factor/dexamethasone mobilization for transfusion purposes. Blood 2009, 113:5979-5998. 10.1182/blood-2008-10-182147, 19349622.
42. Liu TM, Wu YN, Guo XM, Hui JH, Lee EH, Lim B. Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells. Stem Cells Dev 2009, 18:1013-1022. 10.1089/scd.2008.0335, 19102659.
43. Xiao Z, Camalier CE, Nagashima K, Chan KC, Lucas DA, De La Cruz MJ, Gignac M, Lockett S, Issaq HJ, Veenstra TD, Conrads TP, Beck GR. Analysis of the Extracellular Matric Vesicle Proteiome in mineralizing osteoblasts. J Cell Physiol 210:325-335.
44. Aghajanova L, Horcajadas JA, Weeks JL, Esteban FJ, Nezhat CN, Conti M, Giudice LC. The protein kinase A pathway-regulated transcriptome of endometrial stromal fibroblasts reveals compromised differentiation and persistent proliferative potential in endometriosis. Endocrinology 2010, 151:1341-1355. 10.1210/en.2009-0923, 2840687, 20068008.
45. Huang J, Zheng DL, Qin FS, Cheng N, Chen H, Wan BB, Wang YP, Xiao HS, Han ZG. Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling. J Clin Invest 2010, 120:223-241. 10.1172/JCI38012, 2798676, 20038795.
46. Chaerkady R, Harsha HC, Nalli A, Gucek M, Vivekanandan P, Akhtar J, Cole RN, Simmers J, Schulick RD, Singh S, Torbenson M, Pandey A, Thuluvath PJ. A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma. J Proteome Res 2008, 7:4289-4298. 10.1021/pr800197z, 18715028.
47. Schwaenen C, Nessling M, Wessendorf S, Salvi T, Wrobel G, Radlwimmer B, Kestler HA, Haslinger C, Stilgenbauer S, Dohner H, Bentz M, Lichter P. Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations. Proc Natl Acad Sci USA 2004, 101:1039-1044. 10.1073/pnas.0304717101, 327147, 14730057.
48. Albrethsen J, Knol JC, Piersma S, Pham TV, de WM, Mongera S, Carvalho B, Verheul HM, Fijneman RJ, Meijer GA, Jimenez CR. Sub-nuclear proteomics in colorectal cancer:Identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression. Mol Cell Proteomics 2010, 9:988-1005. 10.1074/mcp.M900546-MCP200, 2871429, 20089989.
49. Scholler N, Gross JA, Garvik B, Wells L, Liu Y, Loch CM, Ramirez AB, McIntosh MW, Lampe PD, Urban N. Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery. J Transl Med 2008, 6:41. 10.1186/1479-5876-6-41, 2503970, 18652693.
50. Salani R, Neuberger I, Kurman RJ, Bristow RE, Chang HW, Wang TL, Shih IM. Expression of extracellular matrix proteins in ovarian serous tumors. Int J Gynecol Pathol 2007, 26:141-146. 10.1097/01.pgp.0000229994.02815.f9, 17413980.