Perturbations of vascular homeostasis and aortic valve abnormalities in fibulin-4 deficient mice

Circulation Research

Volumn 100, Issue 5, 2007, Pages 738-746

  Hanada, Katsuhiro ^a,c   Vermeij, Marcel ^a   Garinis, George A ^a   De Waard, Monique C ^a   Kunen, Maurice G S ^a   Myers, Loretha ^b   Maas, Alex ^a   Duncker, Dirk J ^a   Meijers, Carel ^a   Dietz, Harry C ^b   Kanaar, Roland ^a   Essers, Jeroen ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Aneurysm; Aortic valve; Mouse model

Indexed keywords

ENDONUCLEASE; FIBULIN; FIBULIN 4; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; FIBULIN-4; SCLEROPROTEIN;

ALLELE; ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA DISSECTION; AORTA VALVE DISEASE; AORTA VALVE REGURGITATION; APOPTOSIS; ARTICLE; ASCENDING AORTA; CELL ADHESION; CONTROLLED STUDY; CYTOSKELETON; DISEASE SEVERITY; GENE EXPRESSION; GENE TARGETING; HEART DISEASE; HEART VALVE STENOSIS; HETEROZYGOSITY; HOMEOSTASIS; HOMOZYGOSITY; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; AORTA ANEURYSM; AORTA VALVE; BIOSYNTHESIS; C57BL MOUSE; COMPARATIVE STUDY; CONGENITAL MALFORMATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; THORACIC AORTA; TRANSGENIC MOUSE; VALVULAR HEART DISEASE;

ANIMALS; AORTA, THORACIC; AORTIC ANEURYSM; AORTIC VALVE; EXTRACELLULAR MATRIX PROTEINS; HEART VALVE DISEASES; HOMEOSTASIS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 33947713016     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000260181.19449.95     Document Type: Article

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