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Volumn 17, Issue 2, 2011, Pages 181-190

LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway

Author keywords

Apoptosis; Death receptor pathway; Gastric cancer; Ly294002; Oxaliplatin; Phosphatidylino sitol 3' kinase akt pathway

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CASPASE 8; DEATH RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OXALIPLATIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B;

EID: 79955754131     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v17.i2.181     Document Type: Article
Times cited : (23)

References (45)
  • 2
    • 0034651755 scopus 로고    scopus 로고
    • The National Cancer Data Base Report on poor survival of U.S. gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer staging, proximal disease, and the different disease hypothesis
    • Hundahl SA, Phillips JL, Menck HR. The National Cancer Data Base Report on poor survival of U.S. gastric carcinoma patients treated with gastrectomy: Fifth Edition American Joint Committee on Cancer staging, proximal disease, and the different disease hypothesis. Cancer 2000; 88: 921-932
    • (2000) Cancer , vol.88 , pp. 921-932
    • Hundahl, S.A.1    Phillips, J.L.2    Menck, H.R.3
  • 8
    • 33645516362 scopus 로고    scopus 로고
    • Akt-medi-ated cisplatin resistance in ovarian cancer: Modulation of p53 action on caspase-dependent mitochondrial death pathway
    • Yang X, Fraser M, Moll UM, Basak A, Tsang BK. Akt-medi-ated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway. Cancer Res 2006; 66: 3126-3136
    • (2006) Cancer Res , vol.66 , pp. 3126-3136
    • Yang, X.1    Fraser, M.2    Moll, U.M.3    Basak, A.4    Tsang, B.K.5
  • 9
    • 32944466951 scopus 로고    scopus 로고
    • Use and perceived effectiveness of student support services in a frst-year dental student population
    • Burk DT, Bender DJ. Use and perceived effectiveness of student support services in a frst-year dental student population. J Dent Educ 2005; 69: 1148-1160
    • (2005) J Dent Educ , vol.69 , pp. 1148-1160
    • Burk, D.T.1    Bender, D.J.2
  • 11
    • 19544385752 scopus 로고    scopus 로고
    • Upregulated Akt signaling adjacent to gastric cancers: Implications for screening and chemoprevention
    • Ang KL, Shi DL, Keong WW, Epstein RJ. Upregulated Akt signaling adjacent to gastric cancers: implications for screening and chemoprevention. Cancer Lett 2005; 225: 53-59
    • (2005) Cancer Lett , vol.225 , pp. 53-59
    • Ang, K.L.1    Shi, D.L.2    Keong, W.W.3    Epstein, R.J.4
  • 12
    • 33746118057 scopus 로고    scopus 로고
    • Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplas-tic large cell lymphoma
    • Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplas-tic large cell lymphoma. Cancer Res 2006; 66: 6589-6597
    • (2006) Cancer Res , vol.66 , pp. 6589-6597
    • Vega, F.1    Medeiros, L.J.2    Leventaki, V.3    Atwell, C.4    Cho-Vega, J.H.5    Tian, L.6    Claret, F.X.7    Rassidakis, G.Z.8
  • 13
    • 33745857967 scopus 로고    scopus 로고
    • Akt-and CREB-mediated prostate cancer cell proliferation inhibition by Nexrutine, a Phellodendron amurense extract
    • Garcia GE, Nicole A, Bhaskaran S, Gupta A, Kyprianou N, Kumar AP. Akt-and CREB-mediated prostate cancer cell proliferation inhibition by Nexrutine, a Phellodendron amurense extract. Neoplasia 2006; 8: 523-533
    • (2006) Neoplasia , vol.8 , pp. 523-533
    • Garcia, G.E.1    Nicole, A.2    Bhaskaran, S.3    Gupta, A.4    Kyprianou, N.5    Kumar, A.P.6
  • 14
    • 2542451727 scopus 로고    scopus 로고
    • Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion
    • Zhang HM, Rao JN, Guo X, Liu L, Zou T, Turner DJ, Wang JY. Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion. J Biol Chem 2004; 279: 22539-22547
    • (2004) J Biol Chem , vol.279 , pp. 22539-22547
    • Zhang, H.M.1    Rao, J.N.2    Guo, X.3    Liu, L.4    Zou, T.5    Turner, D.J.6    Wang, J.Y.7
  • 15
    • 0033527448 scopus 로고    scopus 로고
    • The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
    • Vanden Berghe W, De Bosscher K, Boone E, Plaisance S, Haegeman G. The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter. J Biol Chem 1999; 274: 32091-32098
    • (1999) J Biol Chem , vol.274 , pp. 32091-32098
    • van den Berghe, W.1    de Bosscher, K.2    Boone, E.3    Plaisance, S.4    Haegeman, G.5
  • 16
    • 77952525651 scopus 로고    scopus 로고
    • The effect of focal adhesion kinase gene silencing on 5-fuorouracil chemosensitivity involves an Akt/NF-kappaB signaling pathway in colorectal carcinomas
    • Chen Y, Wang Z, Chang P, Xiang L, Pan F, Li J, Jiang J, Zou L, Yang L, Bian Z, Liang H. The effect of focal adhesion kinase gene silencing on 5-fuorouracil chemosensitivity involves an Akt/NF-kappaB signaling pathway in colorectal carcinomas. Int J Cancer 2010; 127: 195-206
    • (2010) Int J Cancer , vol.127 , pp. 195-206
    • Chen, Y.1    Wang, Z.2    Chang, P.3    Xiang, L.4    Pan, F.5    Li, J.6    Jiang, J.7    Zou, L.8    Yang, L.9    Bian, Z.10    Liang, H.11
  • 17
    • 30344435005 scopus 로고    scopus 로고
    • Detection of oxaliplatin-induced DNA crosslinks in vitro and in cancer patients using the alkaline comet assay. DNA Repair
    • Almeida GM, Duarte TL, Steward WP, Jones GD. Detection of oxaliplatin-induced DNA crosslinks in vitro and in cancer patients using the alkaline comet assay. DNA Repair (Amst) 2006; 5: 219-225
    • (2006) Amst , vol.5 , pp. 219-225
    • Almeida, G.M.1    Duarte, T.L.2    Steward, W.P.3    Jones, G.D.4
  • 18
    • 0032866230 scopus 로고    scopus 로고
    • Molecular modeling of the intrastrand guanine-guanine DNA adducts produced bycisplatin and oxaliplatin
    • Scheeff ED, Briggs JM, Howell SB. Molecular modeling of the intrastrand guanine-guanine DNA adducts produced bycisplatin and oxaliplatin. Mol Pharmacol 1999; 56: 633-643
    • (1999) Mol Pharmacol , vol.56 , pp. 633-643
    • Scheeff, E.D.1    Briggs, J.M.2    Howell, S.B.3
  • 19
    • 0029814651 scopus 로고    scopus 로고
    • The cellular toxicity of two antitumoural agents derived from platinum, cisplatinum versus oxaliplatinum, on cultures of tubular proximal cells
    • Legallicier B, Leclere C, Monteil C, Elkaz V, Morin JP, Fil-lastre JP. The cellular toxicity of two antitumoural agents derived from platinum, cisplatinum versus oxaliplatinum, on cultures of tubular proximal cells. Drugs Exp Clin Res 1996; 22: 41-50
    • (1996) Drugs Exp Clin Res , vol.22 , pp. 41-50
    • Legallicier, B.1    Leclere, C.2    Monteil, C.3    Elkaz, V.4    Morin, J.P.5    Fil-Lastre, J.P.6
  • 20
    • 0026618635 scopus 로고
    • The current status of new platinum analogs
    • Christian MC. The current status of new platinum analogs. Semin Oncol 1992; 19: 720-733
    • (1992) Semin Oncol , vol.19 , pp. 720-733
    • Christian, M.C.1
  • 21
    • 33745547767 scopus 로고    scopus 로고
    • Chemotherapy in advanced gastric cancer: A systematic review and meta-analysis based on aggregate data
    • Wagner AD, Grothe W, Haerting J, Kleber G, Grothey A, Fleig WE. Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data. J Clin Oncol 2006; 24: 2903-2909
    • (2006) J Clin Oncol , vol.24 , pp. 2903-2909
    • Wagner, A.D.1    Grothe, W.2    Haerting, J.3    Kleber, G.4    Grothey, A.5    Fleig, W.E.6
  • 23
    • 4043050174 scopus 로고    scopus 로고
    • G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells
    • C281-C291
    • Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. Am J Physiol Cell Physiol 2004; 287: C281-C291
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Gao, N.1    Flynn, D.C.2    Zhang, Z.3    Zhong, X.S.4    Walker, V.5    Liu, K.J.6    Shi, X.7    Jiang, B.H.8
  • 24
    • 0036729867 scopus 로고    scopus 로고
    • Inhibition of phosphatidylino-sitol 3-kinase-Akt signaling blocks growth, promotes apopto-sis, and enhances sensitivity of small cell lung cancer cells to chemotherapy
    • Krystal GW, Sulanke G, Litz J. Inhibition of phosphatidylino-sitol 3-kinase-Akt signaling blocks growth, promotes apopto-sis, and enhances sensitivity of small cell lung cancer cells to chemotherapy. Mol Cancer Ther 2002; 1: 913-922
    • (2002) Mol Cancer Ther , vol.1 , pp. 913-922
    • Krystal, G.W.1    Sulanke, G.2    Litz, J.3
  • 25
    • 0038756445 scopus 로고    scopus 로고
    • PTEN and phos-phatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: Evidence for an effect on the tumor and endothelial compartment
    • Su JD, Mayo LD, Donner DB, Durden DL. PTEN and phos-phatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: evidence for an effect on the tumor and endothelial compartment. Cancer Res 2003; 63: 3585-3592
    • (2003) Cancer Res , vol.63 , pp. 3585-3592
    • Su, J.D.1    Mayo, L.D.2    Donner, D.B.3    Durden, D.L.4
  • 26
    • 77956497324 scopus 로고    scopus 로고
    • Responsiveness PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice
    • Polo ML, Arnoni MV, Riggio M, Wargon V, Lanari C, No-varo V. Responsiveness to PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice. PLoS One 2010; 5: e10786
    • (2010) PLoS One , vol.e10786 , pp. 5
    • Polo, M.L.1    Arnoni, M.V.2    Riggio, M.3    Wargon, V.4    Lanari, C.5    No-varo, V.6
  • 27
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-489
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 28
    • 33745458229 scopus 로고    scopus 로고
    • Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma
    • Kobayashi I, Semba S, Matsuda Y, Kuroda Y, Yokozaki H. Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma. Pathobiology 2006; 73: 8-17
    • (2006) Pathobiology , vol.73 , pp. 8-17
    • Kobayashi, I.1    Semba, S.2    Matsuda, Y.3    Kuroda, Y.4    Yokozaki, H.5
  • 29
    • 77955495968 scopus 로고    scopus 로고
    • LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells
    • Shin JY, Kim JO, Lee SK, Chae HS, Kang JH. LY294002 may overcome 5-FU resistance via down-regulation of activated p-AKT in Epstein-Barr virus-positive gastric cancer cells. BMC Cancer 2010; 10: 425
    • (2010) BMC Cancer , vol.10 , pp. 425
    • Shin, J.Y.1    Kim, J.O.2    Lee, S.K.3    Chae, H.S.4    Kang, J.H.5
  • 30
    • 34247606468 scopus 로고    scopus 로고
    • Pleiotropic effects of PI-3' kinase/Akt signaling in human hepatoma cell proliferation and drug-induced apoptosis
    • Alexia C, Bras M, Fallot G, Vadrot N, Daniel F, Lasfer M, Tamouza H, Groyer A. Pleiotropic effects of PI-3' kinase/Akt signaling in human hepatoma cell proliferation and drug-induced apoptosis. Ann N Y Acad Sci 2006; 1090: 1-17
    • (2006) Ann N Y Acad Sci , vol.1090 , pp. 1-17
    • Alexia, C.1    Bras, M.2    Fallot, G.3    Vadrot, N.4    Daniel, F.5    Lasfer, M.6    Tamouza, H.7    Groyer, A.8
  • 31
    • 63149114714 scopus 로고    scopus 로고
    • Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/ hypoxia-inducible factor-1alpha axis
    • Pencreach E, Guérin E, Nicolet C, Lelong-Rebel I, Voegeli AC, Oudet P, Larsen AK, Gaub MP, Guenot D. Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/ hypoxia-inducible factor-1alpha axis. Clin Cancer Res 2009; 15: 1297-1307
    • (2009) Clin Cancer Res , vol.15 , pp. 1297-1307
    • Pencreach, E.1    Guérin, E.2    Nicolet, C.3    Lelong-Rebel, I.4    Voegeli, A.C.5    Oudet, P.6    Larsen, A.K.7    Gaub, M.P.8    Guenot, D.9
  • 32
    • 77955858619 scopus 로고    scopus 로고
    • Cisplatin and PI3kinase inhibition decrease invasion and migration of human ovarian carcinoma cells and regulate matrix-metalloproteinase expression
    • Karam AK, Santiskulvong C, Fekete M, Zabih S, Eng C, Dori-go O. Cisplatin and PI3kinase inhibition decrease invasion and migration of human ovarian carcinoma cells and regulate matrix-metalloproteinase expression. Cytoskeleton (Hoboken) 2010; 67: 535-544
    • (2010) Cytoskeleton (Hoboken) , vol.67 , pp. 535-544
    • Karam, A.K.1    Santiskulvong, C.2    Fekete, M.3    Zabih, S.4    Eng, C.5    Dori-Go, O.6
  • 38
    • 0242656497 scopus 로고    scopus 로고
    • Death receptor-induced cell killing
    • Thorburn A. Death receptor-induced cell killing. Cell Signal 2004; 16: 139-144
    • (2004) Cell Signal , vol.16 , pp. 139-144
    • Thorburn, A.1
  • 39
    • 0037276437 scopus 로고    scopus 로고
    • The CD95(APO-1/Fas) DISC and beyond
    • Peter ME, Krammer PH. The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ 2003; 10: 26-35
    • (2003) Cell Death Differ , vol.10 , pp. 26-35
    • Peter, M.E.1    Krammer, P.H.2
  • 40
    • 0035496099 scopus 로고    scopus 로고
    • Regulation of lymphocyte proliferation and death by FLIP
    • Thome M, Tschopp J. Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol 2001; 1: 50-58
    • (2001) Nat Rev Immunol , vol.1 , pp. 50-58
    • Thome, M.1    Tschopp, J.2
  • 41
    • 57349169369 scopus 로고    scopus 로고
    • Quer-cetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and protea-some-mediated c-FLIPS down-regulation
    • Kim JY, Kim EH, Park SS, Lim JH, Kwon TK, Choi KS. Quer-cetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and protea-some-mediated c-FLIPS down-regulation. J Cell Biochem 2008; 105: 1386-1398
    • (2008) J Cell Biochem , vol.105 , pp. 1386-1398
    • Kim, J.Y.1    Kim, E.H.2    Park, S.S.3    Lim, J.H.4    Kwon, T.K.5    Choi, K.S.6
  • 42
    • 40349091528 scopus 로고    scopus 로고
    • Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis
    • Kim DJ, Park C, Oh B, Kim YY. Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis. J Mol Signal 2008; 3: 2
    • (2008) J Mol Signal , vol.3 , pp. 2
    • Kim, D.J.1    Park, C.2    Oh, B.3    Kim, Y.Y.4
  • 43
    • 0037006003 scopus 로고    scopus 로고
    • The short splice form of Casper/ c-FLIP is a major cellular inhibitor of TRAIL-induced apopto-sis
    • Bin L, Li X, Xu LG, Shu HB. The short splice form of Casper/ c-FLIP is a major cellular inhibitor of TRAIL-induced apopto-sis. FEBS Lett 2002; 510: 37-40
    • (2002) FEBS Lett , vol.510 , pp. 37-40
    • Bin, L.1    Li, X.2    Xu, L.G.3    Shu, H.B.4
  • 44
    • 0035930905 scopus 로고    scopus 로고
    • Alternative splicing variants of c-FLIP transduce the differential signal through the Raf or TRAF2 in TNF-induced cell proliferation
    • Park SJ, Kim YY, Ju JW, Han BG, Park SI, Park BJ. Alternative splicing variants of c-FLIP transduce the differential signal through the Raf or TRAF2 in TNF-induced cell proliferation. Biochem Biophys Res Commun 2001; 289: 1205-1210
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 1205-1210
    • Park, S.J.1    Kim, Y.Y.2    Ju, J.W.3    Han, B.G.4    Park, S.I.5    Park, B.J.6
  • 45
    • 0346399569 scopus 로고    scopus 로고
    • Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers
    • Nam SY, Jung GA, Hur GC, Chung HY, Kim WH, Seol DW, Lee BL. Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers. Cancer Sci 2003; 94: 1066-1073
    • (2003) Cancer Sci , vol.94 , pp. 1066-1073
    • Nam, S.Y.1    Jung, G.A.2    Hur, G.C.3    Chung, H.Y.4    Kim, W.H.5    Seol, D.W.6    Lee, B.L.7


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