-
1
-
-
33748114134
-
One hundred two consecutive hepatobiliary resections for perihilar cholangiocarcinoma with zero mortality
-
1602147 16858186 10.1097/01.sla.0000217605.66519.38
-
Sano T Shimada K Sakamoto Y Yamamoto J Yamasaki S Kosuge T One hundred two consecutive hepatobiliary resections for perihilar cholangiocarcinoma with zero mortality Ann Surg 2006, 244(2):240-247 1602147 16858186 10.1097/01.sla.0000217605.66519.38
-
(2006)
Ann Surg
, vol.244
, Issue.2
, pp. 240-247
-
-
Sano, T.1
Shimada, K.2
Sakamoto, Y.3
Yamamoto, J.4
Yamasaki, S.5
Kosuge, T.6
-
3
-
-
3042562289
-
Phase II trial of capecitabine/irinotecan and capecitabine/oxaliplatin in advanced gastrointestinal cancers
-
10.3816/CCC.2004.n.009 15207020
-
Jordan K Kellner O Kegel T Schmoll H-J Grothey A Phase II trial of capecitabine/irinotecan and capecitabine/oxaliplatin in advanced gastrointestinal cancers Clin Colorectal Cancer 2004, 4(1):46-50 10.3816/ CCC.2004.n.009 15207020
-
(2004)
Clin Colorectal Cancer
, vol.4
, Issue.1
, pp. 46-50
-
-
Jordan, K.1
Kellner, O.2
Kegel, T.3
Schmoll, H.-J.4
Grothey, A.5
-
4
-
-
0033789184
-
Oxaliplatininduced damage of cellular DNA
-
11040038
-
Woynarowski JM Faivre S Herzig MC Arnett B Chapman WG Trevino AV Raymond E Chaney SG Vaisman A Varchenko M Juniewicz PE Oxaliplatininduced damage of cellular DNA Mol Pharmacol 2000, 58(5):920-927 11040038
-
(2000)
Mol Pharmacol
, vol.58
, Issue.5
, pp. 920-927
-
-
Woynarowski, J.M.1
Faivre, S.2
Herzig, M.C.3
Arnett, B.4
Chapman, W.G.5
Trevino, A.V.6
Raymond, E.7
Chaney, S.G.8
Vaisman, A.9
Varchenko, M.10
Juniewicz, P.E.11
-
5
-
-
33750570253
-
Oxaliplatin as first-line treatment in inoperable biliary tract carcinoma: A multicenter phase II study
-
10.1159/000096249 17047399
-
Androulakis N Aravantinos G Syrigos K Polyzos A Ziras N Tselepatiotis E Samonis G Kentepozidis N Giassas S Vamvakas L Georgoulias V Oxaliplatin as first-line treatment in inoperable biliary tract carcinoma: A multicenter phase II study Oncology 2006, 70(4):280-284 10.1159/ 000096249 17047399
-
(2006)
Oncology
, vol.70
, Issue.4
, pp. 280-284
-
-
Androulakis, N.1
Aravantinos, G.2
Syrigos, K.3
Polyzos, A.4
Ziras, N.5
Tselepatiotis, E.6
Samonis, G.7
Kentepozidis, N.8
Giassas, S.9
Vamvakas, L.10
Georgoulias, V.11
-
6
-
-
34247247719
-
Phase II study of epirubicin plus oxaliplatin and infusional 5- fluorouracil as first-line combination therapy in patients with metastatic or advanced gastric cancer
-
10.1097/CAD.0b013e3280146296 17414627
-
Zhang CX Huang S Xu N Fang JW Shen P Bao YH Mou BH Shi MG Zhong XL Xiong PJ Phase II study of epirubicin plus oxaliplatin and infusional 5- fluorouracil as first-line combination therapy in patients with metastatic or advanced gastric cancer Anticancer Drugs 2007, 18(5):581-586 10.1097/CAD.0b013e3280146296 17414627
-
(2007)
Anticancer Drugs
, vol.18
, Issue.5
, pp. 581-586
-
-
Zhang, C.X.1
Huang, S.2
Xu, N.3
Fang, J.W.4
Shen, P.5
Bao, Y.H.6
Mou, B.H.7
Shi, M.G.8
Zhong, X.L.9
Xiong, P.J.10
-
7
-
-
38549175341
-
Capecitabine plus oxaliplatin as first-line treatment in patients with advanced biliary system adenocarcinoma: A prospective multicentre phase II trial
-
10.1038/sj.bjc.6604178 18182984
-
Nehls O Oettle H Hartmann JT Hofheinz RD Hass HG Horger MS Koppenhöfer U Hochhaus A Stieler J Trojan J Gregor M Klump B Capecitabine plus oxaliplatin as first-line treatment in patients with advanced biliary system adenocarcinoma: A prospective multicentre phase II trial Br J Cancer 2008, 98(2):309-315 10.1038/sj.bjc.6604178 18182984
-
(2008)
Br J Cancer
, vol.98
, Issue.2
, pp. 309-315
-
-
Nehls, O.1
Oettle, H.2
Hartmann, J.T.3
Hofheinz, R.D.4
Hass, H.G.5
Horger, M.S.6
Koppenhöfer, U.7
Hochhaus, A.8
Stieler, J.9
Trojan, J.10
Gregor, M.11
Klump, B.12
-
8
-
-
34247600489
-
Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion
-
17461449
-
Leelawat K Leelawat S Narong S Hongeng S Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion World J Gastroenterol 2007, 13(10):1561-1568 17461449
-
(2007)
World J Gastroenterol
, vol.13
, Issue.10
, pp. 1561-1568
-
-
Leelawat, K.1
Leelawat, S.2
Narong, S.3
Hongeng, S.4
-
9
-
-
15544369937
-
Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line
-
10.1016/j.ygyno.2004.11.051 15790433
-
Lee S Choi E-J Jin C Kim D-H Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line Gynecol Oncol 2005, 97(1):26-34 10.1016/j.ygyno.2004.11.051 15790433
-
(2005)
Gynecol Oncol
, vol.97
, Issue.1
, pp. 26-34
-
-
Lee, S.1
Choi, E.-J.2
Jin, C.3
Kim, D.-H.4
-
10
-
-
55549083197
-
Overexpression of cFLIPs inhibits oxaliplatin-mediated apoptosis through enhanced XIAP stability and Akt activation in human renal cancer cells
-
10.1002/jcb.21905 18767116
-
Kim S Lee T-J Park J-W Kwon TK Overexpression of cFLIPs inhibits oxaliplatin-mediated apoptosis through enhanced XIAP stability and Akt activation in human renal cancer cells J Cell Biochem 2008, 105(4):971-979 10.1002/jcb.21905 18767116
-
(2008)
J Cell Biochem
, vol.105
, Issue.4
, pp. 971-979
-
-
Kim, S.1
Lee, T.-J.2
Park, J.-W.3
Kwon, T.K.4
-
11
-
-
1642535431
-
AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression
-
10.1074/jbc.M309999200 14576155
-
Gera JF Mellinghoff IK Shi Y Rettig MB Tran C Hsu JH Sawyers CL Lichtenstein AK AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression J Biol Chem 2004, 279(4);2737-2746 10.1074/jbc.M309999200 14576155
-
(2004)
J Biol Chem
, vol.279
, Issue.4
, pp. 2737-2746
-
-
Gera, J.F.1
Mellinghoff, I.K.2
Shi, Y.3
Rettig, M.B.4
Tran, C.5
Hsu, J.H.6
Sawyers, C.L.7
Lichtenstein, A.K.8
-
12
-
-
33748310873
-
Sequence-dependent inhibition of human colon cancer cell growth and of prosurvival pathways by oxaliplatin in combination with ZD6474 (Zactima), an inhibitor of VEGFR and EGFR tyrosine kinases
-
10.1158/1535-7163.MCT-06-0055 16891475
-
Troiani T Lockerbie O Morrow M Ciardiello F Eckhardt SG Sequence-dependent inhibition of human colon cancer cell growth and of prosurvival pathways by oxaliplatin in combination with ZD6474 (Zactima), an inhibitor of VEGFR and EGFR tyrosine kinases Mol Cancer Ther 2006, 5(7):1883-1894 10.1158/1535-7163.MCT-06-0055 16891475
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.7
, pp. 1883-1894
-
-
Troiani, T.1
Lockerbie, O.2
Morrow, M.3
Ciardiello, F.4
Eckhardt, S.G.5
-
13
-
-
34147192199
-
Cholangiocarcinoma: Emerging approaches to a challenging cancer
-
10.1097/MOG.0b013e3280495451 17414849
-
Patel T Singh P Cholangiocarcinoma: Emerging approaches to a challenging cancer Curr Opin Gastroenterol 2007, 23(3):317-323 10.1097/ MOG.0b013e3280495451 17414849
-
(2007)
Curr Opin Gastroenterol
, vol.23
, Issue.3
, pp. 317-323
-
-
Patel, T.1
Singh, P.2
-
14
-
-
33847637698
-
Randomized phase II three-arm trial with three platinum-based doublets in metastatic non-small-cell lung cancer. An Italian Trials in Medical Oncology study
-
10.1093/annonc/mdl415 17110590
-
Bidoli P Zilembo N Cortinovis D Mariani L Isa L Aitini E Cullurà D Pari F Nova P Mancin M Formisano B Bajetta E Randomized phase II three-arm trial with three platinum-based doublets in metastatic non-small-cell lung cancer. An Italian Trials in Medical Oncology study Ann Oncol 2007, 18(3):461-467 10.1093/annonc/mdl415 17110590
-
(2007)
Ann Oncol
, vol.18
, Issue.3
, pp. 461-467
-
-
Bidoli, P.1
Zilembo, N.2
Cortinovis, D.3
Mariani, L.4
Isa, L.5
Aitini, E.6
Cullurà, D.7
Pari, F.8
Nova, P.9
Mancin, M.10
Formisano, B.11
Bajetta, E.12
-
15
-
-
24944522719
-
Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy
-
10.1158/0008-5472.CAN-05-0058 16166321
-
Tsurutani J West KA Sayyah J Gills JJ Dennis PA Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy Cancer Res 2005, 65(18):8423-8432 10.1158/ 0008-5472.CAN-05-0058 16166321
-
(2005)
Cancer Res
, vol.65
, Issue.18
, pp. 8423-8432
-
-
Tsurutani, J.1
West, K.A.2
Sayyah, J.3
Gills, J.J.4
Dennis, P.A.5
-
16
-
-
34548557199
-
Functional analysis of the gene expression profiles of colorectal cancer cell lines in relation to oxaliplatin and cisplatin cytotoxicity
-
17390068
-
Meynard D Le Morvan V Bonnet J Robert J Functional analysis of the gene expression profiles of colorectal cancer cell lines in relation to oxaliplatin and cisplatin cytotoxicity Oncol Rep 2007, 17(5):1213-1221 17390068
-
(2007)
Oncol Rep
, vol.17
, Issue.5
, pp. 1213-1221
-
-
Meynard, D.1
Le Morvan, V.2
Bonnet, J.3
Robert, J.4
-
17
-
-
0032570815
-
Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis
-
10.1074/jbc.273.9.5315 9478990
-
Ueki K Yamamoto-Honda R Kaburagi Y Yamauchi T Tobe K Burgering BM Coffer PJ Komuro I Akanuma Y Yazaki Y Kadowaki T Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis J Biol Chem 1998, 273(9):5315-5322 10.1074/ jbc.273.9.5315 9478990
-
(1998)
J Biol Chem
, vol.273
, Issue.9
, pp. 5315-5322
-
-
Ueki, K.1
Yamamoto-Honda, R.2
Kaburagi, Y.3
Yamauchi, T.4
Tobe, K.5
Burgering, B.M.6
Coffer, P.J.7
Komuro, I.8
Akanuma, Y.9
Yazaki, Y.10
Kadowaki, T.11
-
18
-
-
54949144410
-
mTOR inhibitors in the treatment of cancer
-
10.1517/13543784.17.11.1717 18922108
-
Fasolo A Sessa C mTOR inhibitors in the treatment of cancer Expert Opin Investig Drugs 2008, 17(11):1717-1734 10.1517/13543784.17.11.1717 18922108
-
(2008)
Expert Opin Investig Drugs
, vol.17
, Issue.11
, pp. 1717-1734
-
-
Fasolo, A.1
Sessa, C.2
-
19
-
-
45149094232
-
Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data
-
18332467
-
Tanaka C O'Reilly T Kovarik JM Shand N Hazell K Judson I Raymond E Zumstein-Mecker S Stephan C Boulay A Hattenberger M Thomas G Lane HA Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data J Clin Oncol 2008, 26(10):1596-1602 18332467
-
(2008)
J Clin Oncol
, vol.26
, Issue.10
, pp. 1596-1602
-
-
Tanaka, C.1
O'Reilly, T.2
Kovarik, J.M.3
Shand, N.4
Hazell, K.5
Judson, I.6
Raymond, E.7
Zumstein-Mecker, S.8
Stephan, C.9
Boulay, A.10
Hattenberger, M.11
Thomas, G.12
Lane, H.A.13
-
20
-
-
20244365941
-
The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation
-
10.1016/j.cell.2004.12.040 15797377
-
Beuvink I Boulay A Fumagalli S Zilbermann F Ruetz S O'Reilly T Natt F Hall J Lane HA Thomas G The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation Cell 2005, 120(6):747-759 10.1016/j.cell.2004.12.040 15797377
-
(2005)
Cell
, vol.120
, Issue.6
, pp. 747-759
-
-
Beuvink, I.1
Boulay, A.2
Fumagalli, S.3
Zilbermann, F.4
Ruetz, S.5
O'Reilly, T.6
Natt, F.7
Hall, J.8
Lane, H.A.9
Thomas, G.10
-
21
-
-
34547130295
-
RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model
-
10.1158/1078-0432.CCR-06-2770 17634556
-
Mabuchi S Altomare DA Cheung M Zhang L Poulikakos PI Hensley HH Schilder RJ Ozols RF Testa JR RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model Clin Cancer Res 2007, 13(14):4261-4270 10.1158/1078-0432.CCR-06-2770 17634556
-
(2007)
Clin Cancer Res
, vol.13
, Issue.14
, pp. 4261-4270
-
-
Mabuchi, S.1
Altomare, D.A.2
Cheung, M.3
Zhang, L.4
Poulikakos, P.I.5
Hensley, H.H.6
Schilder, R.J.7
Ozols, R.F.8
Testa, J.R.9
-
22
-
-
32944457518
-
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
-
10.1158/0008-5472.CAN-05-2925 16452206
-
O'Reilly KE Rojo F She QB Solit D Mills GB Smith D Lane H Hofmann F Hicklin DJ Ludwig DL Baselga J Rosen N mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt Cancer Res 2006, 66(3):1500-1508 10.1158/0008-5472.CAN-05-2925 16452206
-
(2006)
Cancer Res
, vol.66
, Issue.3
, pp. 1500-1508
-
-
O'Reilly, K.E.1
Rojo, F.2
She, Q.B.3
Solit, D.4
Mills, G.B.5
Smith, D.6
Lane, H.7
Hofmann, F.8
Hicklin, D.J.9
Ludwig, D.L.10
Baselga, J.11
Rosen, N.12
|