-
1
-
-
33745530860
-
The many paths to p38 mitogen-activated protein kinase activation in the immune system
-
Ashwell JD. The many paths to p38 mitogen-activated protein kinase activation in the immune system. Nat Rev Immunol 2006; 6: 532-540.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 532-540
-
-
Ashwell, J.D.1
-
2
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
Roux PP, Blenis J. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 2004; 68: 320-344.
-
(2004)
Microbiol Mol Biol Rev
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
3
-
-
0033965158
-
The p38 signal transduction pathway: Activation and function
-
Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal 2000; 12: 1-13.
-
(2000)
Cell Signal
, vol.12
, pp. 1-13
-
-
Ono, K.1
Han, J.2
-
4
-
-
19644367000
-
Activation and signaling of the p38 MAP kinase pathway
-
Zarubin T, Han J. Activation and signaling of the p38 MAP kinase pathway. Cell Res 2005; 15: 11-18.
-
(2005)
Cell Res
, vol.15
, pp. 11-18
-
-
Zarubin, T.1
Han, J.2
-
5
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and infammation
-
Kyriakis JM, Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and infammation. Physiol Rev 2001; 81: 807-869.
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
6
-
-
0033120590
-
Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in infamma-tory cell lineages
-
Hale KK, Trollinger D, Rihanek M, Manthey CL. Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in infamma-tory cell lineages. J Immunol 1999; 162: 4246-4252.
-
(1999)
J Immunol
, vol.162
, pp. 4246-4252
-
-
Hale, K.K.1
Trollinger, D.2
Rihanek, M.3
Manthey, C.L.4
-
7
-
-
0029982565
-
Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
-
Jiang y, Chen C, Li Z, guo W, gegner JA, Lin S, et al. Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta). J Biol Chem 1996; 271: 17920-17926.
-
(1996)
J Biol Chem
, vol.271
, pp. 17920-17926
-
-
Jiang, Y.1
Chen, C.2
Li, Z.3
Guo, W.4
Gegner, J.A.5
Lin, S.6
-
8
-
-
0031587929
-
Novel homologues of CSBP/p38 MAP kinase: Activation, substrate specifcity and sensitivity to inhibition by pyridinyl imidazoles
-
Kumar S, McDonnell PC, gum RJ, Hand AT, Lee JC, young PR. Novel homologues of CSBP/p38 MAP kinase: activation, substrate specifcity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun 1997; 235: 533-538.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 533-538
-
-
Kumar, S.1
McDonnell, P.C.2
Gum, R.J.3
Hand, A.T.4
Lee, J.C.5
Young, P.R.6
-
9
-
-
0030581626
-
The primary structure of p38 gamma: A new member of p38 group of MAP kinases
-
Li Z, Jiang Y, Ulevitch RJ, Han J. The primary structure of p38 gamma: a new member of p38 group of MAP kinases. Biochem Biophys Res Commun 1996; 228: 334-340.
-
(1996)
Biochem Biophys Res Commun
, vol.228
, pp. 334-340
-
-
Li, Z.1
Jiang, Y.2
Ulevitch, R.J.3
Han, J.4
-
10
-
-
33746139320
-
Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-infammatory cytokines
-
Funding AT, Johansen C, Kragballe K, Otkjaer K, Jensen UB, Madsen MW, et al. Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-infammatory cytokines. J Invest Dermatol 2006; 126: 1784-1791.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1784-1791
-
-
Funding, A.T.1
Johansen, C.2
Kragballe, K.3
Otkjaer, K.4
Jensen, U.B.5
Madsen, M.W.6
-
11
-
-
63149088840
-
Reduced oxazolone-induced skin infammation in MAPKAP kinase 2 knockout mice
-
Funding AT, Johansen C, gaestel M, Bibby BM, Lilleholt LL, Kragballe K, et al. Reduced oxazolone-induced skin infammation in MAPKAP kinase 2 knockout mice. J Invest Dermatol 2009; 129: 891-898.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 891-898
-
-
Funding, A.T.1
Johansen, C.2
Gaestel, M.3
Bibby, B.M.4
Lilleholt, L.L.5
Kragballe, K.6
-
12
-
-
13244284850
-
The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin
-
Johansen C, Kragballe K, Westergaard M, Henningsen J, Kristiansen K, Iversen L. The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin. Br J Dermatol 2005; 152: 37-42.
-
(2005)
Br J Dermatol
, vol.152
, pp. 37-42
-
-
Johansen, C.1
Kragballe, K.2
Westergaard, M.3
Henningsen, J.4
Kristiansen, K.5
Iversen, L.6
-
13
-
-
31144468296
-
Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2
-
Johansen C, Funding AT, Otkjaer K, Kragballe K, Jensen UB, Madsen M, et al. Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2. J Immunol 2006; 176: 1431-1438.
-
(2006)
J Immunol
, vol.176
, pp. 1431-1438
-
-
Johansen, C.1
Funding, A.T.2
Otkjaer, K.3
Kragballe, K.4
Jensen, U.B.5
Madsen, M.6
-
14
-
-
0037020247
-
Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity
-
Takanami-Ohnishi y, Amano S, Kimura S, Asada S, Utani A, Maruyama M, et al. Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity. J Biol Chem 2002; 277: 37896-37903.
-
(2002)
J Biol Chem
, vol.277
, pp. 37896-37903
-
-
Takanami-Ohnishi Y.Amano, S.1
Kimura, S.2
Asada, S.3
Utani, A.4
Maruyama, M.5
-
15
-
-
33746745351
-
Topical p38MAPK inhibition reduces dermal infammation and epithelial apoptosis in burn wounds
-
Ipaktchi K, Mattar A, Niederbichler AD, Hoesel LM, Hemmila MR, Su GL, et al. Topical p38MAPK inhibition reduces dermal infammation and epithelial apoptosis in burn wounds. Shock 2006; 26: 201-209.
-
(2006)
Shock
, vol.26
, pp. 201-209
-
-
Ipaktchi, K.1
Mattar, A.2
Niederbichler, A.D.3
Hoesel, L.M.4
Hemmila, M.R.5
Su, G.L.6
-
16
-
-
0035896611
-
MEK7-dependent activation of p38 MAP kinase in keratinocytes
-
Dashti SR, Efmova T, Eckert RL. MEK7-dependent activation of p38 MAP kinase in keratinocytes. J Biol Chem 2001; 276: 8059-8063.
-
(2001)
J Biol Chem
, vol.276
, pp. 8059-8063
-
-
Dashti, S.R.1
Efmova, T.2
Eckert, R.L.3
-
17
-
-
0038636455
-
P38 Mitogen-activated protein kinases on the body surface - a function for p38 delta
-
Eckert RL, Efmova T, Balasubramanian S, Crish JF, Bone F, Dashti S. p38 Mitogen-activated protein kinases on the body surface - a function for p38 delta. J Invest Dermatol 2003; 120: 823-828.
-
(2003)
J Invest Dermatol
, vol.120
, pp. 823-828
-
-
Eckert, R.L.1
Efmova, T.2
Balasubramanian, S.3
Crish, J.F.4
Bone, F.5
Dashti, S.6
-
18
-
-
38049018155
-
A quantitative analysis of kinase inhibitor selectivity
-
Karaman MW, Herrgard S, Treiber DK, gallant P, Atteridge CE, Campbell BT, et al. A quantitative analysis of kinase inhibitor selectivity. Nat Biotechnol 2008; 26: 127-132.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 127-132
-
-
Karaman, M.W.1
Herrgard, S.2
Treiber, D.K.3
Gallant, P.4
Atteridge, C.E.5
Campbell, B.T.6
-
19
-
-
0033622470
-
Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development
-
Adams RH, Porras A, Alonso G, Jones M, Vintersten K, Panelli S, et al. Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development. Mol Cell 2000; 6: 109-116.
-
(2000)
Mol Cell
, vol.6
, pp. 109-116
-
-
Adams, R.H.1
Porras, A.2
Alonso, G.3
Jones, M.4
Vintersten, K.5
Panelli, S.6
-
20
-
-
0034610981
-
Defciency of the stress kinase p38alpha results in embryonic lethality: Characterization of the kinase dependence of stress responses of enzyme-defcient embryonic stem cells
-
Allen M, Svensson L, Roach M, Hambor J, McNeish J, Gabel CA. Defciency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-defcient embryonic stem cells. J Exp Med 2000; 191: 859-870.
-
(2000)
J Exp Med
, vol.191
, pp. 859-870
-
-
Allen, M.1
Svensson, L.2
Roach, M.3
Hambor, J.4
McNeish, J.5
Gabel, C.A.6
-
21
-
-
0034641614
-
Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis
-
Mudgett JS, Ding J, guh-Siesel L, Chartrain NA, yang L, gopal S, et al. Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc Natl Acad Sci USA 2000; 97: 10454-10459.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10454-10459
-
-
Mudgett, J.S.1
Ding, J.2
Guh-Siesel, L.3
Chartrain, N.A.4
Yang, L.5
Gopal, S.6
-
22
-
-
50049122380
-
The kinase p38 alpha serves cell type-specifc infammatory functions in skin injury and coordinates pro- and anti-infammatory gene expression
-
Kim C, Sano Y, Todorova K, Carlson BA, Arpa L, Celada A, et al. The kinase p38 alpha serves cell type-specifc infammatory functions in skin injury and coordinates pro- and anti-infammatory gene expression. Nat Immunol 2008; 9: 1019-1027.
-
(2008)
Nat Immunol
, vol.9
, pp. 1019-1027
-
-
Kim, C.1
Sano, Y.2
Todorova, K.3
Carlson, B.A.4
Arpa, L.5
Celada, A.6
-
23
-
-
36849034334
-
Chemical genetics defne the roles of p38alpha and p38beta in acute and chronic infammation
-
O'Keefe SJ, Mudgett JS, Cupo S, Parsons JN, Chartrain NA, Fitzgerald C, et al. Chemical genetics defne the roles of p38alpha and p38beta in acute and chronic infammation. J Biol Chem 2007; 282: 34663-34671.
-
(2007)
J Biol Chem
, vol.282
, pp. 34663-34671
-
-
O'Keefe, S.J.1
Mudgett, J.S.2
Cupo, S.3
Parsons, J.N.4
Chartrain, N.A.5
Fitzgerald, C.6
-
24
-
-
27944461325
-
Generation and characterization of p38beta (MAPK11) gene-targeted mice
-
Beardmore VA, Hinton HJ, Eftychi C, Apostolaki M, Armaka M, Darragh J, et al. generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol Cell Biol 2005; 25: 10454-10464.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10454-10464
-
-
Beardmore, V.A.1
Hinton, H.J.2
Eftychi, C.3
Apostolaki, M.4
Armaka, M.5
Darragh, J.6
-
25
-
-
20244365497
-
P38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with gKAP
-
Sabio G, Arthur JS, Kuma Y, Peggie M, Carr J, Murray-Tait V, et al. p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with gKAP. EMBO J 2005; 24: 1134-1145.
-
(2005)
EMBO J
, vol.24
, pp. 1134-1145
-
-
Sabio, G.1
Arthur, J.S.2
Kuma, Y.3
Peggie, M.4
Carr, J.5
Murray-Tait, V.6
-
26
-
-
0020051148
-
Measurement of cutaneous infammation: Estimation of neutrophil content with an enzyme marker
-
Bradley PP, Priebat DA, Christensen RD, Rothstein G. Measurement of cutaneous infammation: estimation of neutrophil content with an enzyme marker. J Invest Der-matol 1982; 78: 206-209.
-
(1982)
J Invest Der-matol
, vol.78
, pp. 206-209
-
-
Bradley, P.P.1
Priebat, D.A.2
Christensen, R.D.3
Rothstein, G.4
-
27
-
-
27544481752
-
The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis
-
Otkjaer K, Kragballe K, Funding AT, Clausen JT, Noerby PL, Steiniche T, et al. The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis. Br J Dermatol 2005; 153: 911-918.
-
(2005)
Br J Dermatol
, vol.153
, pp. 911-918
-
-
Otkjaer, K.1
Kragballe, K.2
Funding, A.T.3
Clausen, J.T.4
Noerby, P.L.5
Steiniche, T.6
-
28
-
-
66349138173
-
P38delta mitogen-activated protein kinase is essential for skin tumor development in mice
-
Schindler EM, Hindes A, gribben EL, Burns CJ, Yin Y, Lin MH, et al. p38delta mitogen-activated protein kinase is essential for skin tumor development in mice. Cancer Res 2009; 69: 4648-4655.
-
(2009)
Cancer Res
, vol.69
, pp. 4648-4655
-
-
Schindler, E.M.1
Hindes, A.2
Gribben, E.L.3
Burns, C.J.4
Yin, Y.5
Lin, M.H.6
-
29
-
-
34248591664
-
Mouse models of psoriasis
-
gudjonsson JE, Johnston A, Dyson M, Valdimarsson H, Elder JT. Mouse models of psoriasis. J Invest Dermatol 2007; 127: 1292-1308.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1292-1308
-
-
Gudjonsson, J.E.1
Johnston, A.2
Dyson, M.3
Valdimarsson, H.4
Elder, J.T.5
-
30
-
-
66449084405
-
P38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms
-
Kwong J, Hong L, Liao R, Deng Q, Han J, Sun P. p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms. J Biol Chem 2009; 284: 11237-11246.
-
(2009)
J Biol Chem
, vol.284
, pp. 11237-11246
-
-
Kwong, J.1
Hong, L.2
Liao, R.3
Deng, Q.4
Han, J.5
Sun, P.6
-
31
-
-
33846808922
-
Hyperactive variants of p38alpha induce, whereas hyperactive variants of p38gamma suppress, activating protein 1-mediated transcription
-
Askari N, Diskin R, Avitzour M, Capone R, Livnah O, Engelberg D. Hyperactive variants of p38alpha induce, whereas hyperactive variants of p38gamma suppress, activating protein 1-mediated transcription. J Biol Chem 2007; 282: 91-99.
-
(2007)
J Biol Chem
, vol.282
, pp. 91-99
-
-
Askari, N.1
Diskin, R.2
Avitzour, M.3
Capone, R.4
Livnah, O.5
Engelberg, D.6
-
32
-
-
50049086910
-
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling
-
Ananieva O, Darragh J, Johansen C, Carr JM, McIlrath J, Park JM, et al. The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. Nat Immunol 2008; 9: 1028-1036.
-
(2008)
Nat Immunol
, vol.9
, pp. 1028-1036
-
-
Ananieva, O.1
Darragh, J.2
Johansen, C.3
Carr, J.M.4
McIlrath, J.5
Park, J.M.6
|