Endogenous amyloidogenesis in long-term rat hippocampal cell cultures

BMC Neuroscience

Volumn 12, Issue , 2011, Pages

  Bertrand, Sarah J ^a   Aksenova, Marina V ^a   Aksenov, Micheal Y ^a   Mactutus, Charles F ^a   Booze, Rosemarie M ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cell Culture Amyloid Peptide; Neurodegeneration Aging

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CONGO RED; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; NEURON SPECIFIC ENOLASE; POSTSYNAPTIC DENSITY PROTEIN 95; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

AMYLOIDOGENESIS; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL AGING; CELL DEGENERATION; CELL MATURATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOCHEMISTRY; DENDRITE; FETUS; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MACROGLIA; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NONHUMAN; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; STAINING; VALIDITY; AGING; AMYLOID PLAQUE; ANIMAL; CELL CULTURE; METABOLISM; NERVE CELL; PATHOLOGY; SPRAGUE DAWLEY RAT;

AGING; AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; CELLS, CULTURED; HIPPOCAMPUS; NEURONS; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79955730917     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-12-38     Document Type: Article

References (40)

1. Brewer GJ, Torricelli JR, Evege EK, Price PJ. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res 1993, 35(5):567-76. 10.1002/jnr.490350513, 8377226.
2. Brewer GJ, Torricelli JR. Isolation and culture of adult neurons and neurospheres. Nat Protoc 2007, 2(6):1490-8. 10.1038/nprot.2007.207, 17545985.
3. Brewer GJ. Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture. Exp Neurol 1999, 159(1):237-47. 10.1006/exnr.1999.7123, 10486191.
4. Aksenova MV, Aksenov MY, Mactutus CF, Booze RM. Cell culture models of oxidative stress and injury in the central nervous system. Curr Neurovasc Res 2005, 2(1):73-89. 10.2174/1567202052773463, 16181101.
5. Aksenova MV, Aksenov MY, Markesbery WR, Butterfield DA. Aging in a dish: age-dependent changes of neuronal survival, protein oxidation, and creatine kinase BB expression in long-term hippocampal cell culture. J Neurosci Res 1999, 58(2):308-17. 10.1002/(SICI)1097-4547(19991015)58:2<308::AID-JNR11>3.0.CO;2-#, 10502287.
6. Lesuisse C, Martin LJ. Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death. J Neurobiol 2002, 51(1):9-23. 10.1002/neu.10037, 11920724.
7. Brewer GJ, Lim A, Capps NG, Torricelli JR. Age-related calcium changes, oxyradical damage, caspase activation and nuclear condensation in response to glutamate and beta-amyloid. Exp Gerontol 2005, 40:426-437. 10.1016/j.exger.2005.03.007, 15919595.
8. Kim MJ, Oh SJ, Park SH, Kang HJ, Won MH, Kang TC, Park JB, Kim JI, Kim J, Lee JY. Neuronal loss in primary long-term cortical culture involves neurodegeneration-like cell death via calpain and p35 processing, but not developmental apoptosis or aging. Exp Mol Med 2007, 39(1):14-26.
9. Costantini C, Lorenzetto E, Cellini B, Buffelli M, Rossi F, Della-Bianca V. Astrocytes regulate the expression of insulin-like growth factor 1 receptor (IGF1-R) in primary cortical neurons during in vitro senescence. J Mol Neurosci 2010, 40(3):342-52. 10.1007/s12031-009-9305-5, 19862643.
10. Kaech S, Banker G. Culturing hippocampal neurons. Nat Protoc 2006, 1(5):2406-15. 10.1038/nprot.2006.356, 17406484.
11. Paek SH, Shin HY, Kim JW, Park SH, Son JH, Kim DG. Primary culture of central neurocytoma: a case report. J Korean Med Sci 2010, 25:798-803. 10.3346/jkms.2010.25.5.798, 2858845, 20436722.
12. Palm K, Salin-Nordstrom T, Levesque MF, Neuman T. Fetal and adult human CNS stem cells have similar molecular characteristics and developmental potential. Molecular Brain Research 2000, 78:192-195. 10.1016/S0169-328X(00)00075-9, 10891600.
13. Varghese K, Das M, Bhargava N, Stancescu M, Molnar P, Kinda MS, Hickman JJ. Regeneration and characterization of adult mouse hippocampal neurons in a defined in vitro system. J of Neuroscience Methods 2009, 177:51-59.
14. Eliasson C, Sahlgren C, Berthold CH, Stakeberg J, Celis JE, Betsholtz C, Eriksson JE, Pekny M. Intermediate filament protein partnership in astrocytes. J of BioChem 1999, 274(34):23996-24006.
15. Esteban JA. Living with the enemy: a physiological role for the β-amyloid peptide. Trends in Neuroscience 2004, 27:1-3.
16. Pearson HA, Pears C. Physiological roles for amyloid β peptides. J Physiol 2006, 575:5-10. 10.1113/jphysiol.2006.111203, 1819417, 16809372.
17. Beach TG. Physiologic origins of age-related beta-amyloid deposition. Neurodegener Dis 2008, 5(3-4):143-5. 10.1159/000113685, 18322373.
18. Lindner AB, Demarez A. Protein aggregation as a paradigm of aging. Biochim Biophys Acta 2009, 1790(10):980-996.
19. Nakamura T, Lipton SA. Cell death: protein misfolding and neurodegenerative diseases. Apoptosis 2009, 14(4):455-468. 10.1007/s10495-008-0301-y, 19130231.
20. Lesné S, Ali C, Gabriel C, Croci N, MacKenzie ET, Glabe CG, Plotkine M, Marchand-Verrechia C, Vivien D, Buisson A. NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. J Neurosci 2005, 25(41):9367-9377. 10.1523/JNEUROSCI.0849-05.2005, 16221845.
21. Kametani F. Epsilon-secretase: reduction of amyloid precursor protein epsilon-site cleavage in Alzheimer's disease. Curr Alzheimer Res 2008, (5):165-171.
22. Kamenetz F, Tomita T, Hsieh H, Seabrook G, Borchelt D, Iwatsubo T, Sisodia S, Malinow R. APP processing and synaptic function. Neuron 2003, 37:925-937. 10.1016/S0896-6273(03)00124-7, 12670422.
23. Puzzo D, Privitera L, Leznik E, Fà M, Staniszewski A, Palmeri A, Arancio O. Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus. J Neurosci 2008, 28:14537-14545. 10.1523/JNEUROSCI.2692-08.2008, 2673049, 19118188.
24. Rohan de Silva HA, Jen A, Wickenden C, Jen LS, Wilkinson SL, Patel AJ. Cell-specific expression of beta-amyloid precursor protein isoform mRNAs and proteins in neurons and astrocytes. Brain Res Mol Brain Res 1997, 47(1-2):147-156.
25. Sarasa M, Pesini P. Natural non-transgenic animal models for research in Alzheimer's disease. Current Alzheimer Research 2009, 6:171-178. 10.2174/156720509787602834, 2825666, 19355852.
26. Liu RT, Zou LB, Lu QJ. Liquiritigenin inhibits Aβ25-35-induced neurotoxicity and secretion of Aβ1-40 in rat hippocampal neurons. Acta Pharmacologica Sinica 2009, 30:899-906. 10.1038/aps.2009.74, 19574995.
27. Hensley K, Hall N, Subramaniam R, Cole P, Harris M, Aksenov M, Aksenova M, Gabbita SP, Wu JF, Carney JM, Lovell M, Markesbery WR, Butterfield DA. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. J Neurochem 1995, 65(5):2146-2156.
28. Selkoe DJ. Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav Brain Res 2008, 192:106-113. 10.1016/j.bbr.2008.02.016, 2601528, 18359102.
29. Boyd-Kimball D, Sultana R, Mohmmad-Abdul H, Butterfield DA. Rodent Abeta(1-42) exhibits oxidative stress properties similar to those of human Abeta(1-42): Implications for proposed mechanisms of toxicity. J Alzheimers Dis 2005, 6(5):515-525.
30. Matrone C, Ciotti MT, Mercanti D, Marolda R, Calissano P. NGF and BDNF signaling control amyloidogenic route and Aβ production in hippocampal neurons. PNAS 2008, 105(35):13139-13144. 10.1073/pnas.0806133105, 2525562, 18728191.
31. Brewer GJ. Effects of acidosis on the distribution of processing of the beta-amyloid precursor protein in cultured hippocampal neurons. Mol Chem Neuropathol 1997, 31(2):171-86. 10.1007/BF02815241, 9376023.
32. Misonou H, Trimmer JS. A primary culture system for biochemical analyses of neuronal proteins. J Neuroscience Methods 2005, 144:165-173.
33. Diez-Vives C, Gay M, Garcia-Matas S, Comellas F, Carrascal M, Abian J, Ortega-Aznar A, Cristofol R, Sanfeliu C. Proteomic study of neuron and astrocyte cultures from senescence-accelerated mouse SAMP8 reveals degenerative changes. J Neurochemistry 2009, 111:945-955.
34. Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Ostaszewski BL, Schenk D, Teplow DB, Selkoe DJ. Amyloid β-peptide is produced by cultured cells during normal metabolism. Nature 1992, 359:322-325. 10.1038/359322a0, 1383826.
35. Butterfield DA, Yatin SM, Varadarajan S, Koppal T. Amyloid-beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease. Methods Enzymol 1999, 309:746-748.
36. Yatin SM, Varadarajan S, Link CD, Butterfield DA. In vitro and in vivo oxidative stress associated with Alzheimer's amyloid-beta peptide (1-42). Neurobiol Aging 1999, 20:338-342.
37. Moro ML, Collins MJ, Cappellini E. Alzheimer's disease and amyloid β-peptide deposition in the brain: a matter of 'aging'?. Biochem Soc Trans 2010, 38:539-544. 10.1042/BST0380539, 20298218.
38. Wakabayashi M, Matsuzaki K. Formation of amyloids by Abeta-(1-42) on NGF-differentiated PC12 cells: roles of gangliosides and cholesterol. J Mol Biol 2007, 371:924-933. 10.1016/j.jmb.2007.06.008, 17597153.
39. Aksenov MY, Aksenova MV, Mactutus CF, Booze RM. HIV-1 protein-mediated amyloidogenesis in rat hippocampal cell culture. Neuroscience Letters 2010, 45:174-178.
40. Aksenov MY, Aksenova MV, Mactutus CF, Booze RM. Attenuated neurotoxicity of the transactivation-defective HIV-1 Tat protein in hippocampal cell cultures. Exp Neurol 2009, 219:586-590. 10.1016/j.expneurol.2009.07.005, 2770879, 19615365.