Impact of solvent conditions on separation and detection of basic drugs by micro liquid chromatography-mass spectrometry under overloading conditions

Journal of Chromatography A

Volumn 1218, Issue 22, 2011, Pages 3413-3422

  Schubert, Birthe ^a   Oberacher, Herbert ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Basic pharmaceuticals; Electrospray ionization; Mass spectrometry; Micro liquid chromatography; Overloading; Reversed phase chromatography

Indexed keywords

BASIC PHARMACEUTICALS; ELECTROSPRAYS; MICRO-LIQUID CHROMATOGRAPHY; OVERLOADING; REVERSED-PHASE CHROMATOGRAPHY;

ACETIC ACID; CATALYST ACTIVITY; ELECTROSPRAY IONIZATION; FORMIC ACID; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; PYRIDINE; QUALITY CONTROL;

CHROMATOGRAPHY;

3,4 METHYLENEDIOXYAMPHETAMINE; ACETIC ACID; BUNITROLOL; CAFFEINE; COCAINE; CODEINE; DIAZEPAM; DOXEPIN; FORMIC ACID; HALOPERIDOL; METHANSULFONIC ACID; MORPHINE; NICOTINE; PENTAFLUOROPROPIONIC ACID; PERFLUOROBUTYRIC ACID; SHORT CHAIN FATTY ACID; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG; ZOLPIDEM;

ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; IONIZATION; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS;

ACETIC ACID; CHROMATOGRAPHY, REVERSE-PHASE; HUMANS; HYDROGEN-ION CONCENTRATION; PHARMACEUTICAL PREPARATIONS; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 79955720304     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.03.051     Document Type: Article

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