Ultrasensitive quantification of serum vitamin D metabolites using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry

Analytical Chemistry

Volumn 82, Issue 6, 2010, Pages 2488-2497

  Duan, Xiaotao ^a   Weinstock Guttman, Bianca ^a   Wang, Hao ^a   Bang, Eunjln ^a   Li, Jun ^a   Ramanathan, Murall ^a   Qu, Jun ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE METABOLITES; ANALYTES; BAND-BROADENING; CLINICAL ANALYSIS; CLINICAL INVESTIGATION; CLINICAL STUDY; DERIVATIZATIONS; DETECTABILITY; HEALTHY SUBJECTS; ION SUPPRESSION; IONIZATION EFFICIENCY; ISOTOPE DILUTION MASS SPECTROMETRY; LC/MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LOWER LIMIT OF QUANTIFICATIONS; MATRIX; MICRO-FLOW; MULTIPLE SCLEROSIS; OVER CAPACITY; QUANTITATIVE ACCURACY; SAMPLE MATRIX; SELECTIVE SOLID-PHASE EXTRACTION; SERUM SAMPLES; ULTRASENSITIVE; VITAMIN-D;

BIOMOLECULES; BODY FLUIDS; IONIZATION OF LIQUIDS; ISOTOPES; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METABOLITES; SOLAR RADIATION; SOLVENT EXTRACTION;

METABOLISM;

VITAMIN D;

ADULT; ARTICLE; BLOOD; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MIDDLE AGED; SOLID PHASE EXTRACTION; STATISTICAL PARAMETERS; VALIDATION STUDY;

ADULT; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; LIMIT OF DETECTION; MALE; MASS SPECTROMETRY; MIDDLE AGED; SOLID PHASE EXTRACTION; VITAMIN D;

EID: 77949799231     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac902869y     Document Type: Article

References (34)

1. Smolders, J.; Damoiseaux, J.; Menheere, P.; Hupperts, R. J. Neuroimmunol 2008, 194, 7-17.
2. Houghton, L. A.; Vieth, R. Am. J. Clin. Nutr. 2006, 84, 694-697.
3. Zerwekh, J. E. Am. J. Clin. Nutr. 2008, 87, 1087S-1091S.
4. Norman, A. W.; Okamura, W. H.; Farach-Carson, M. C.; Allewaert, K.; Branisteanu, D.; Nemere, I.; Muralidharan, K. R.; Bouillon, R. J. Biol Chem. 1993, 268, 13811-13819.
5. Seo, E. G.; Norman, A. W. J. Bone Miner. Res. 1997, 12, 598-606.
6. Carter, G. D. Clin. Chem. 2009, 55, 1300-1302.
7. Roth, H. J.; Schmidt-Gayk, H.; Weber, H.; Niederau, C. Ann. Clin. Biochem. 2008, 45, 153-159.
8. Haddad, J. G.; Chyu, K J. J. Clin. Endocrinol Metab. 1971, 33, 992-995.
9. Jones, G. Clin. Chem. 1978, 24, 287-298.
10. Tsugawa, N.; Suhara, Y.; Kamao, M.; Okano, T. Anal. Chem. 2005, 77, 3001-3007.
11. Maunsell, Z.; Wright, D. J.; Rainbow, S. J. Clin. Chem. 2005, 51, 16831690.
12. Higashi, T.; Awada, D.; Shimada, K. Biol. Pharm. Bull. 2001, 24, 738743.
13. Vogeser, M.; Kyriatsoulis, A.; Huber, E.; Kobold, U. Clin. Chem. 2004, 50, 1415-1417.
14. Aronov, P. A.; Hall, L. M.; Dettmer, K.; Stephensen, C. B.; Hammock, B. D. Anal. Bioanal. Chem. 2008, 391, 1917-1930.
15. Qu, J.; Qu, Y.; Straubinger, R. M. Anal. Chem. 2007, 79, 3786-3793.
16. Yu, H.; Straubinger, R. M.; Cao, J.; Wang, H.; Qu, J. J. Chromatogr., A 2008, 1210, 160-167.
17. Gaspar, J. R.; Qu, J.; Straubinger, N. L.; Straubinger, R. M. Analyst 2008, 133, 1742-1748.
18. Khatri, B. O. Ther. Apheris 2000, 4, 263-270.
19. Weinstock-Guttman, B.; Bakshi, R. CNS Drugs 2004, 18, 777-792.
20. Ozgocmen, S.; Bulut, S.; Ilhan, N.; Gulkesen, A.; Ardicoglu, O.; Ozkan, Y. J. Bone Miner. Metab. 2005, 23, 309-313.
21. Munger, K. L.; Levin, L. I.; Hollis, B. W.; Howard, N. S.; Ascherio, A. JAMA 2006, 296, 2832-2838.
22. Embry, A. F.; Snowdon, L. R.; Vieth, R. Ann. Neurol 2000, 48, 271-272.
23. Cantorna, M. T.; Hayes, C. E.; DeLuca, H. F. Proc. Natl. Acad. Sci. U. S. A . 1996, 93, 7861-7864.
24. Mahon, B. D.; Gordon, S. A.; Cruz, J.; Cosman, F.; Cantorna, M. T. J. Neuroimmunol 2003, 134, 128-132.
25. McDonald, W. I.; Compston, A.; Edan, G.; Goodkin, D.; Hartung, H. P.; Lublin, F. D.; McFarland, H. F.; Paty, D. W.; Polman, C. H.; Reingold, S. C.; Sandberg-Wollheim, M.; Sibley, W.; Thompson, A.; van den Noort, S.; Weinshenker, B. Y.; Wolinsky, J. S. Ann. Neurol 2001, 50, 121-127.
26. Kurtzke, J. F. Neurology 1983, 33, 1444-1452.
27. White, P.; Cooke, N. Trends Endocrinol. Metab. 2000, 11, 320-327.
28. Eyles, D.; Anderson, C.; Ko, P.; Jones, A.; Thomas, A.; Burne, T; Mortensen, P. B.; Norgaard-Pedersen, B.; Hougaard, D. M.; McGrath, J. Clin. Chim. Ada 2009, 403, 145-151.
29. Duan, X.; Young, R.; Straubinger, R. M.; Page, B.; Cao, J.; Wang, H.; Yu, H.; Canty, J. M.; Qu, J. J. Proteome Res. 2009, 8, 2838-2850.
30. Lewis, J. G.; Elder, P. A. Clin. Chem. 2008, 54, 1931-1932.
31. Hollis, B. W. Detection of vitamin D and its major metabolites. In Vitamin D, 2nd ed,; Feldman, D., Pike, J. W., Glorieux, F. H., Eds.; Elsevier/ Academic Press; New York, 2005.
32. Barnes, M. S.; Bonham, M. P.; Robson, P. J.; Strain, J. J.; Lowe-Strong, A. S.; Eaton-Evans, J.; Ginty, F.; Wallace, J. M. Mult. Scler. 2007,13, 670672.
33. Smolders, J.; Menheere, P.; Kessels, A.; Damoiseaux, J.; Hupperts, R. Mult. Scler. 2008, 14, 1220-1224.
34. Akeno, N.; Saikatsu, S.; Kawane, T.; Horiuchi, N. Endocrinology 1997,138, 2233-2240.