Streptococcus mutans strains recovered from caries-active or caries-free individuals differ in sensitivity to host antimicrobial peptides

Molecular Oral Microbiology

Volumn 26, Issue 3, 2011, Pages 187-199

  Phattarataratip, E ^a,b   Olson, B ^a   Broffitt, B ^a   Qian, F ^a   Brogden, K A ^a   Drake, D R ^a   Levy, S M ^a   Banas, J A ^a  

^a UNIVERSITY OF IOWA   (United States)

^b CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Defensins; Dental caries; Innate immunity; Saliva; Streptococcus mutans

Indexed keywords

ALPHA DEFENSIN; ALPHA DEFENSIN 1; ALPHA DEFENSIN 2; ALPHA DEFENSIN 3; BETA DEFENSIN; BETA DEFENSIN 2; BETA DEFENSIN 3; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; OLIGONUCLEOTIDE; POLYPEPTIDE ANTIBIOTIC AGENT; SALIVA PROTEIN; UNCLASSIFIED DRUG;

ADOLESCENT; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COUNT; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; COLONY FORMING UNIT; CONTROLLED STUDY; DENTAL CARIES; DNA EXTRACTION; DNA FINGERPRINTING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; MOUTH CAVITY; NONHUMAN; NORMAL HUMAN; OPTICAL DENSITY; POLYMERASE CHAIN REACTION; PROTEIN ISOLATION; RANDOMIZED CONTROLLED TRIAL; STREPTOCOCCUS MUTANS;

ADOLESCENT; ALPHA-DEFENSINS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL LOAD; BETA-DEFENSINS; DENTAL CARIES; DENTAL PLAQUE; DMF INDEX; DNA FINGERPRINTING; FEMALE; GENOTYPE; HUMANS; LIPOPOLYSACCHARIDES; MALE; MICROBIAL SENSITIVITY TESTS; MULTIGENE FAMILY; SALIVA; SALIVARY PROTEINS AND PEPTIDES; STREPTOCOCCUS MUTANS; TOOTH;

EID: 79955718024     PISSN: 20411006     EISSN: 20411014     Source Type: Journal    
DOI: 10.1111/j.2041-1014.2011.00607.x     Document Type: Article

References (60)

1. Abiko, Y. and Saitoh, M. (2007) Salivary defensins and their importance in oral health and disease. Curr Pharm Des 13: 3065-3072.
2. Bartie, K.L., Devine, D.A., Wilson, M.J. and Lewis, M.A. (2008) In vitro susceptibility of the Streptococcus milleri group to antimicrobial peptides. Int Endod J 41: 586-592.
3. Bowden, G.H. and Li, Y.H. (1997) Nutritional influences on biofilm development. Adv Dent Res 11: 81-99.
4. Bradshaw, D.J., Marsh, P.D., Schilling, K.M. and Cummins, D. (1996) A modified chemostat system to study the ecology of oral biofilms. J Appl Bacteriol 80: 124-130.
5. Bradway, S.D., Bergey, E.J., Jones, P.C. and Levine, M.J. (1989) Oral mucosal pellicle. Adsorption and transpeptidation of salivary components to buccal epithelial cells. Biochem J 261: 887-896.
6. Chung, W.O. and Dale, B.A. (2004) Innate immune response of oral and foreskin keratinocytes: utilization of different signaling pathways by various bacterial species. Infect Immun 72: 352-358.
7. Dale, B.A. and Fredericks, L.P. (2005) Antimicrobial peptides in the oral environment: expression and function in health and disease. Curr Issues Mol Biol 7: 119-133.
8. Dawson, J.R. and Ellen, R.P. (1990) Tip-oriented adherence of Treponema denticola to fibronectin. Infect Immun 58: 3924-3928.
9. DeForge, L.E., Billeci, K.L. and Kramer, S.M. (2000) Effect of IFN-gamma on the killing of S. aureus in human whole blood. Assessment of bacterial viability by CFU determination and by a new method using alamarBlue. J Immunol Methods 245: 79-89.
10. Eberhard, J., Pietschmann, R., Falk, W., Jepsen, S. and Dommisch, H. (2009) The immune response of oral epithelial cells induced by single-species and complex naturally formed biofilms. Oral Microbiol Immunol 24: 325-330.
11. Everhart, D.L., Grigsby, W.R. and Carter, W.H. Jr (1973) Human dental caries experience related to age, sex, race, and certein salivary properties. J Dent Res 52: 242-247.
12. Gibbons, R.J. and Hay, D.I. (1989) Adsorbed salivary acidic proline-rich proteins contribute to the adhesion of Streptococcus mutans JBP to apatitic surfaces. J Dent Res 68: 1303-1307.
13. Groisman, E.A., Parra-Lopez, C., Salcedo, M., Lipps, C.J. and Heffron, F. (1992) Resistance to host antimicrobial peptides is necessary for Salmonella virulence. Proc Natl Acad Sci USA 89: 11939-11943.
14. Ji, S., Kim, Y., Min, B.M., Han, S.H. and Choi, Y. (2007) Innate immune responses of gingival epithelial cells to nonperiodontopathic and periodontopathic bacteria. J Periodontal Res 42: 503-510.
15. Johnson, R.B. (2005) Racial differences in salivary sIgA concentrations in postmenopausal women. Spec Care Dentist 25: 145-149.
16. Joly, S., Maze, C., McCray, P.B. Jr and Guthmiller, J.M. (2004) Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms. J Clin Microbiol 42: 1024-1029.
17. Joly, S., Organ, C.C., Johnson, G.K., McCray, P.B. Jr and Guthmiller, J.M. (2005) Correlation between beta-defensin expression and induction profiles in gingival keratinocytes. Mol Immunol 42: 1073-1084.
18. Kimball, J.R., Nittayananta, W., Klausner, M., Chung, W.O. and Dale, B.A. (2006) Antimicrobial barrier of an in vitro oral epithelial model. Arch Oral Biol 51: 775-783.
19. Krisanaprakornkit, S., Kimball, J.R., Weinberg, A., Darveau, R.P., Bainbridge, B.W. and Dale, B.A. (2000) Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier. Infect Immun 68: 2907-2915.
20. Krogstad, D. and Moellering, R.C. (1986) Antimicrobial combinations. In: Lorian, V. ed. Antibiotics in Laboratory Medicine. Baltimore, MD: Williams and Wilkins, 537-595.
21. Levy, S.M., Warren, J.J., Davis, C.S., Kirchner, H.L., Kanellis, M.J. and Wefel, J.S. (2001) Patterns of fluoride intake from birth to 36months. J Public Health Dent 61: 70-77.
22. Maisetta, G., Batoni, G., Esin, S. et al. (2003) Activity of human beta-defensin 3 alone or combined with other antimicrobial agents against oral bacteria. Antimicrob Agents Chemother 47: 3349-3351.
23. Martin, A., Camacho, M., Portaels, F. and Palomino, J.C. (2003) Resazurin microtiter assay plate testing of Mycobacterium tuberculosis susceptibilities to second-line drugs: rapid, simple, and inexpensive method. Antimicrob Agents Chemother 47: 3616-3619.
24. Martin, A., Morcillo, N., Lemus, D. et al. (2005) Multicenter study of MTT and resazurin assays for testing susceptibility to first-line anti-tuberculosis drugs. Int J Tuberc Lung Dis 9: 901-906.
25. Mathews, M., Jia, H.P., Guthmiller, J.M. et al. (1999) Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands. Infect Immun 67: 2740-2745.
26. Mizukawa, N., Sugiyama, K., Fukunaga, J. et al. (1998) Defensin-1, a peptide detected in the saliva of oral squamous cell carcinoma patients. Anticancer Res 18: 4645-4649.
27. Mizukawa, N., Sugiyama, K., Ueno, T., Mishima, K., Takagi, S. and Sugahara, T. (1999a) Defensin-1, an antimicrobial peptide present in the saliva of patients with oral diseases. Oral Dis 5: 139-142.
28. Mizukawa, N., Sugiyama, K., Ueno, T., Mishima, K., Takagi, S. and Sugahara, T. (1999b) Levels of human defensin-1, an antimicrobial peptide, in saliva of patients with oral inflammation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 87: 539-543.
29. Montoro, E., Lemus, D., Echemendia, M., Martin, A., Portaels, F. and Palomino, J.C. (2005) Comparative evaluation of the nitrate reduction assay, the MTT test, and the resazurin microtitre assay for drug susceptibility testing of clinical isolates of Mycobacterium tuberculosis. J Antimicrob Chemother 55: 500-505.
30. Nishimura, E., Eto, A., Kato, M. et al. (2004a) Oral streptococci exhibit diverse susceptibility to human beta-defensin-2: antimicrobial effects of hBD-2 on oral streptococci. Curr Microbiol 48: 85-87.
31. + regulatory T cells. Int Immunol 16: 1189-1201.
32. Nizet, V., Ohtake, T., Lauth, X. et al. (2001) Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 414: 454-457.
33. Oberg, S.G., Izutsu, K.T. and Truelove, E.L. (1982) Human parotid saliva protein composition: dependence on physiological factors. Am J Physiol 242: G231-G236.
34. Ouhara, K., Komatsuzawa, H., Yamada, S. et al. (2005) Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, beta-defensins and LL37, produced by human epithelial cells. J Antimicrob Chemother 55: 888-896.
35. Perron, G.G., Zasloff, M. and Bell, G. (2006) Experimental evolution of resistance to an antimicrobial peptide. Proc Biol Sci 273: 251-256.
36. Pettit, R.K., Weber, C.A., Kean, M.J. et al. (2005) Microplate Alamar blue assay for Staphylococcus epidermidis biofilm susceptibility testing. Antimicrob Agents Chemother 49: 2612-2617.
37. Rantonen, P.J. and Meurman, J.H. (2000) Correlations between total protein, lysozyme, immunoglobulins, amylase, and albumin in stimulated whole saliva during daytime. Acta Odontol Scand 58: 160-165.
38. Russell, M.W. and Mansson-Rahemtulla, B. (1989) Interaction between surface protein antigens of Streptococcus mutans and human salivary components. Oral Microbiol Immunol 4: 106-111.
39. Scannapieco, F.A. (1994) Saliva-bacterium interactions in oral microbial ecology. Crit Rev Oral Biol Med 5: 203-248.
40. Scannapieco, F.A., Torres, G. and Levine, M.J. (1993) Salivary alpha-amylase: role in dental plaque and caries formation. Crit Rev Oral Biol Med 4: 301-307.
41. Scannapieco, F.A., Torres, G.I. and Levine, M.J. (1995) Salivary amylase promotes adhesion of oral streptococci to hydroxyapatite. J Dent Res 74: 1360-1366.
42. Shimotoyodome, A., Kobayashi, H., Tokimitsu, I. et al. (2007) Saliva-promoted adhesion of Streptococcus mutans MT8148 associates with dental plaque and caries experience. Caries Res 41: 212-218.
43. Singh, P.K., Tack, B.F., McCray, P.B. Jr and Welsh, M.J. (2000) Synergistic and additive killing by antimicrobial factors found in human airway surface liquid. Am J Physiol Lung Cell Mol Physiol 279: L799-L805.
44. Sivakumar, T., Hand, A.R. and Mednieks, M. (2009) Secretory proteins in the saliva of children. J Oral Sci 51: 573-580.
45. Stinson, M.W., Levine, M.J., Cavese, J.M. et al. (1982) Adherence of Streptococcus sanguis to salivary mucin bound to glass. J Dent Res 61: 1390-1393.
46. Sugimoto, J., Kanehira, T., Mizugai, H., Chiba, I. and Morita, M. (2006) Relationship between salivary histatin 5 levels and Candida CFU counts in healthy elderly. Gerodontology 23: 164-169.
47. Taguchi, Y. and Imai, H. (2006) Expression of beta-defensin-2 in human gingival epithelial cells in response to challenge with Porphyromonas gingivalis in vitro. J Periodontal Res 41: 334-339.
48. Tallarida, R.J. (2001) Drug synergism: its detection and applications. J Pharmacol Exp Ther 298: 865-872.
49. Tallarida, R.J. (2006) An overview of drug combination analysis with isobolograms. J Pharmacol Exp Ther 319: 1-7.
50. Tao, R., Jurevic, R.J., Coulton, K.K. et al. (2005) Salivary antimicrobial peptide expression and dental caries experience in children. Antimicrob Agents Chemother 49: 3883-3888.
51. Tenover, F.C., Swenson, J.M., O'Hara, C.M. and Stocker, S.A. (1995) Ability of commercial and reference antimicrobial susceptibility testing methods to detect vancomycin resistance in enterococci. J Clin Microbiol 33: 1524-1527.
52. Vanitha, J.D. and Paramasivan, C.N. (2004) Evaluation of microplate Alamar blue assay for drug susceptibility testing of Mycobacterium avium complex isolates. Diagn Microbiol Infect Dis 49: 179-182.
53. Vankeerberghen, A., Nuytten, H., Dierickx, K., Quirynen, M., Cassiman, J.J. and Cuppens, H. (2005) Differential induction of human beta-defensin expression by periodontal commensals and pathogens in periodontal pocket epithelial cells. J Periodontol 76: 1293-1303.
54. Warren, J.J., Levy, S.M. and Kanellis, M.J. (2001) Prevalence of dental fluorosis in the primary dentition. J Public Health Dent 61: 87-91.
55. Weinberg, A., Krisanaprakornkit, S. and Dale, B.A. (1998) Epithelial antimicrobial peptides: review and significance for oral applications. Crit Rev Oral Biol Med 9: 399-414.
56. Wu, M., McClellan, S.A., Barrett, R.P. and Hazlett, L.D. (2009a) Beta-defensin-2 promotes resistance against infection with P. aeruginosa. J Immunol 182: 1609-1616.
57. Wu, M., McClellan, S.A., Barrett, R.P., Zhang, Y. and Hazlett, L.D. (2009b) Beta-defensins 2 and 3 together promote resistance to Pseudomonas aeruginosa keratitis. J Immunol 183: 8054-8060.
58. Yajko, D.M., Madej, J.J., Lancaster, M.V. et al. (1995) Colorimetric method for determining MICs of antimicrobial agents for Mycobacterium tuberculosis. J Clin Microbiol 33: 2324-2327.
59. Yang, D., Biragyn, A., Hoover, D.M., Lubkowski, J. and Oppenheim, J.J. (2004) Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense. Annu Rev Immunol 22: 181-215.
60. Zakhary, G.M., Clark, R.M., Bidichandani, S.I., Owen, W.L., Slayton, R.L. and Levine, M. (2007) Acidic proline-rich protein Db and caries in young children. J Dent Res 86: 1176-1180.