-
1
-
-
0035051412
-
MDR1 pharmacogenetics: Frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity
-
DOI 10.1097/00008571-200104000-00005
-
Ameyaw, M.M., Regateiro, F., Li, T., Liu, X., Tariq, M., Mobarek, A., Thornton, N., Folayan, G.O., Githang'a, J., Indalo, A., Ofori-Adjei, D., Price-Evans, D.A., McLeod, H.L., 2001. MDR1 pharmacogenetics: frequency of the C3435Tmutation in exon 26 is significantly influenced by ethnicity. Pharmacogenetics 11 (3), 217-221. (Pubitemid 32319871)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.3
, pp. 217-221
-
-
Ameyaw, M.-M.1
Regateiro, F.2
Li, T.3
Liu, X.4
Tariq, M.5
Mobarek, A.6
Thornton, N.7
Folayan, G.O.8
Githang'a, J.9
Indalo, A.10
Ofori-Adjei, D.11
Price-Evans, D.A.12
McLeod, H.L.13
-
2
-
-
33846271368
-
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein
-
DOI 10.1016/j.neuropharm.2006.07.038, PII S002839080600270X
-
Baltes, S., Gastens, A.M., Fedrowitz, M., Potschka, H., Kaever, V., Loscher, W., 2007. Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein. Neruopharmacology 52, 333-346. (Pubitemid 46123353)
-
(2007)
Neuropharmacology
, vol.52
, Issue.2
, pp. 333-346
-
-
Baltes, S.1
Gastens, A.M.2
Fedrowitz, M.3
Potschka, H.4
Kaever, V.5
Loscher, W.6
-
3
-
-
46949108804
-
The influence of C3435T polymorphism of ABCB1 gene on penetration of phenobarbital across blood-brain barrier in patients with generalized epilepsy
-
Basic, S., Hajnsek, S., Bozina, N., Filipcic, I., Sporis, D., Mislov, D., Posavec, A., 2008. The influence of C3435T polymorphism of ABCB1 gene on penetration of phenobarbital across blood-brain barrier in patients with generalized epilepsy. Seizure Eur. J. Epilepsy 17 (6), 524-530.
-
(2008)
Seizure Eur. J. Epilepsy
, vol.17
, Issue.6
, pp. 524-530
-
-
Basic, S.1
Hajnsek, S.2
Bozina, N.3
Filipcic, I.4
Sporis, D.5
Mislov, D.6
Posavec, A.7
-
4
-
-
63849243164
-
Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: A meta-analysis
-
Bournissen, F.G., Moretti, M.E., Juurlink, D.N., Koren, G., Walker, M., Finkelstein, Y., 2008. Polymorphism of the MDR1/ABCB1 C3435T drug-transporter and resistance to anticonvulsant drugs: a meta-analysis. Epilepsia 50 (4), 898-903.
-
(2008)
Epilepsia
, vol.50
, Issue.4
, pp. 898-903
-
-
Bournissen, F.G.1
Moretti, M.E.2
Juurlink, D.N.3
Koren, G.4
Walker, M.5
Finkelstein, Y.6
-
5
-
-
33847625066
-
Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs
-
DOI 10.1111/j.1528-1167.2006.00960.x
-
Cucullo, L., Hossain, M., Rapp, E., Manders, T., Marchi, N., Janigro, D., 2007. Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs. Epilepsia 48, 505-516. (Pubitemid 46365189)
-
(2007)
Epilepsia
, vol.48
, Issue.3
, pp. 505-516
-
-
Cucullo, L.1
Hossain, M.2
Rapp, E.3
Manders, T.4
Marchi, N.5
Janigro, D.6
-
6
-
-
0035669389
-
Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy
-
DOI 10.1046/j.1528-1157.2001.12301.x
-
Dombrowski, S.M., Desai, S.Y., Marroni, M., Cucullo, L., Goodrich, K., Bingaman, W., Matberg, M.R., Bengez, L., Janigro, D., 2001. Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy. Epilepsia 42 (12), 1501-1506. (Pubitemid 34020086)
-
(2001)
Epilepsia
, vol.42
, Issue.12
, pp. 1501-1506
-
-
Dombrowski, S.M.1
Desai, S.Y.2
Marroni, M.3
Cucullo, L.4
Goodrich, K.5
Bingaman, W.6
Mayberg, M.R.7
Bengez, L.8
Janigro, D.9
-
7
-
-
33645745372
-
Adult epilepsy
-
Duncan, J.S., Sander, J.W., Sisodiya, S.M., Walker, M.C., 2006. Adult epilepsy. Lancet 367 (9516), 1087-1100.
-
(2006)
Lancet
, vol.367
, Issue.9516
, pp. 1087-1100
-
-
Duncan, J.S.1
Sander, J.W.2
Sisodiya, S.M.3
Walker, M.C.4
-
8
-
-
34447501746
-
Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: A gene polymorphism perspective study
-
Ebid, A.H., Ahmed, M.M., Mohammed, S.A., 2007. Therapeutic drug monitoring and clinical outcomes in epileptic Egyptian patients: a gene polymorphism perspective study.Ther.Drug Monit. 29 (3), 305-312.
-
(2007)
Ther.Drug Monit.
, vol.29
, Issue.3
, pp. 305-312
-
-
Ebid, A.H.1
Ahmed, M.M.2
Mohammed, S.A.3
-
9
-
-
3242785620
-
Importance of P-glycoprotein at blood-tissue barriers
-
Fromm, M.F., 2004. Importance of P-glycoprotein at blood-tissue barriers. Trends Pharmacol. Sci. 25 (8), 423-429.
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, Issue.8
, pp. 423-429
-
-
Fromm, M.F.1
-
10
-
-
4544383423
-
Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans
-
Giessmann, T., May, K., Modess, C., Wegner, D., Hecker, U., Zschiesche, M., Dazert, P., Grube, M., Schroeder, E., Warzok, R., Cascorbi, I., Kroemer, H.K., Siegmund, W., 2004. Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans. Clin. Pharmacol. Ther. 76 (3), 192-200.
-
(2004)
Clin. Pharmacol. Ther.
, vol.76
, Issue.3
, pp. 192-200
-
-
Giessmann, T.1
May, K.2
Modess, C.3
Wegner, D.4
Hecker, U.5
Zschiesche, M.6
Dazert, P.7
Grube, M.8
Schroeder, E.9
Warzok, R.10
Cascorbi, I.11
Kroemer, H.K.12
Siegmund, W.13
-
11
-
-
34247093310
-
- rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats
-
DOI 10.1111/j.1528-1167.2006.00939.x
-
Hoffmann, K., Loscher, W., 2007. Upregulation of brain expression of P-glycoprotein in MRP2-deficient TR(-) rats resembles seizure-induced up-regulation of this drug efflux transporter in normal rats. Epilepsia 48, 631-645. (Pubitemid 46587614)
-
(2007)
Epilepsia
, vol.48
, Issue.4
, pp. 631-645
-
-
Hoffmann, K.1
Loscher, W.2
-
12
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer, S., Burk, O., von Richter, O., Arnold, H.P., Brochmoller, J., Johne, A., Cascorbi, I., Gerloff, T., Roots, I., Eichelbaum, M., Brinkmann, U., 2000. Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. U. S. A. 97 (7), 3473-3478.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, Issue.7
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brochmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
Brinkmann, U.11
-
13
-
-
21444449353
-
Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response
-
DOI 10.1517/14622416.6.4.411
-
Hung, C.C., Tai, J.J., Lin, C.J., Lee, M.J., Liou, H.H., 2005. Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response. Pharmacogenomics 6 (4), 411-417. (Pubitemid 40916364)
-
(2005)
Pharmacogenomics
, vol.6
, Issue.4
, pp. 411-417
-
-
Hung, C.-C.1
Tai, J.J.2
Lin, C.-J.3
Lee, M.-J.4
Liou, H.-H.5
-
14
-
-
35348848498
-
Association of polymorphisms in NR1I2 and ABCB1 genes with epilepsy treatment responses
-
Hung, C.C., Jen Tai, J., Kao, P.J., Lin, M.S., Liou, H.H., 2007. Association of polymorphisms in NR1I2 and ABCB1 genes with epilepsy treatment responses. Pharmacogenomics 8 (9), 1151-1158.
-
(2007)
Pharmacogenomics
, vol.8
, Issue.9
, pp. 1151-1158
-
-
Hung, C.C.1
Jen Tai, J.2
Kao, P.J.3
Lin, M.S.4
Liou, H.H.5
-
15
-
-
0036667955
-
MDR1 single nucleotide polymorphisms: Multiplicity of haplotypes and functional consequences
-
DOI 10.1097/00008571-200208000-00002
-
Kim, R.B., 2002.MDR1 single nucleotide polymorphisms: multiplicity of haplotypes and functional consequences. Pharmacogenetics 12 (6), 425-427. (Pubitemid 34913525)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.6
, pp. 425-427
-
-
Kim, R.B.1
-
16
-
-
60949100347
-
Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy
-
Kim, D.W., Lee, S.K., Chu, K., Jang, I.J., Yu, K.S., Cho, J.Y., Kim, S.J., 2009. Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy. Epilepsy Res. 84, 86-90.
-
(2009)
Epilepsy Res.
, vol.84
, pp. 86-90
-
-
Kim, D.W.1
Lee, S.K.2
Chu, K.3
Jang, I.J.4
Yu, K.S.5
Cho, J.Y.6
Kim, S.J.7
-
17
-
-
33846504706
-
A"silent" polymorphism in the MDR1 gene changes substrate specificity
-
Kimchi-Sarfaty, C., Oh, J.M., Kim, I.W., Sauna, Z.E., Calcagno, A.M., Ambudkar, S.V., Gottesman, M.M., 2007.A"silent" polymorphism in the MDR1 gene changes substrate specificity. Science 315, 525-528.
-
(2007)
Science
, vol.315
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.W.3
Sauna, Z.E.4
Calcagno, A.M.5
Ambudkar, S.V.6
Gottesman, M.M.7
-
18
-
-
34548726841
-
Silent SNPs: Impact on gene function and phenotype
-
DOI 10.2217/14622416.8.8.1075
-
Komar, A.A., 2007. Silent SNPs: impact on gene function and phenotype. Pharmacogenomics 8 (8), 1075-1080. (Pubitemid 47423694)
-
(2007)
Pharmacogenomics
, vol.8
, Issue.8
, pp. 1075-1080
-
-
Komar, A.A.1
-
19
-
-
13244298981
-
Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
-
DOI 10.1111/j.0013-9580.2005.31904.x
-
Kwan, P., Brodie, M.J., 2005. Potential role of drug transporters in the pathogenesis of medically intractable epilepsy. Epilepsia 6 (2), 224-235. (Pubitemid 40194666)
-
(2005)
Epilepsia
, vol.46
, Issue.2
, pp. 224-235
-
-
Kwan, P.1
Brodie, M.J.2
-
20
-
-
34447619872
-
Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese
-
DOI 10.1016/j.yebeh.2007.04.013, PII S1525505007001540
-
Kwan, P., Baum, L., Wong, V., Ng, P.W., Lui, C.H., Sin, N.C., Hui, A.C., Yu, E., Wong, L.K., 2007. Association between ABCB1 C3435T polymorphism and drug-resistant epilepsy in Han Chinese. Epilepsy Behav. 11 (1), 112-117. (Pubitemid 47087203)
-
(2007)
Epilepsy and Behavior
, vol.11
, Issue.1
, pp. 112-117
-
-
Kwan, P.1
Baum, L.2
Wong, V.3
Ng, P.W.4
Lui, C.H.5
Sin, N.C.6
Hui, A.C.F.7
Yu, E.8
Wong, L.K.S.9
-
21
-
-
66849129225
-
Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese
-
Kwan, P., Wong, V., Ng, P.W., Lui, C.H., Sin, N.C., Poon, W.S., Ng, H. K., Wong, K.S., Baum, L., 2009. Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese. Pharmacogenomics 10 (5), 723-732.
-
(2009)
Pharmacogenomics
, vol.10
, Issue.5
, pp. 723-732
-
-
Kwan, P.1
Wong, V.2
Ng, P.W.3
Lui, C.H.4
Sin, N.C.5
Poon, W.S.6
Ng, H.K.7
Wong, K.S.8
Baum, L.9
-
22
-
-
77954625557
-
Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
-
Kwan, P., Arzimanoglou, A., Berg, A.T., Brodie, M.J., Allen Hauser, W., Mathern, G., Moshé, S.L., Perucca, E., Wiebe, S., French, J., 2010. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 51, 1069-1077.
-
(2010)
Epilepsia
, vol.51
, pp. 1069-1077
-
-
Kwan, P.1
Arzimanoglou, A.2
Berg, A.T.3
Brodie, M.J.4
Allen Hauser, W.5
Mathern, G.6
Moshé, S.L.7
Perucca, E.8
Wiebe, S.9
French, J.10
-
23
-
-
77958016107
-
Imaging of P-glycoprotein function and expression to elucidatemechanisms of pharmacoresistance in epilepsy
-
Loscher, W., Langer, O., 2010. Imaging of P-glycoprotein function and expression to elucidatemechanisms of pharmacoresistance in epilepsy. Curr. Top. Med. Chem. 10 (17), 1785-1791.
-
(2010)
Curr. Top. Med. Chem.
, vol.10
, Issue.17
, pp. 1785-1791
-
-
Loscher, W.1
Langer, O.2
-
24
-
-
0036128985
-
Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
-
Loscher, W., Potschka, H., 2002. Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. J. Pharmacol. Exp. Ther. 301 (1), 7-14.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, Issue.1
, pp. 7-14
-
-
Loscher, W.1
Potschka, H.2
-
25
-
-
23044500398
-
Drug resistance in brain diseases and the role of drug efflux transporters
-
Loscher, W., Potschka, H., 2005. Drug resistance in brain diseases and the role of drug efflux transporters. Nat. Rev. Neurosci. 6 (8), 591-602.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, Issue.8
, pp. 591-602
-
-
Loscher, W.1
Potschka, H.2
-
26
-
-
58149231251
-
The clinical impact of pharmacogenetics on the treatment of epilepsy
-
Loscher, W., Klotz, U., Zimprich, F., Schmidt, D., 2009. The clinical impact of pharmacogenetics on the treatment of epilepsy. Epilepsia 50 (1), 1-23.
-
(2009)
Epilepsia
, vol.50
, Issue.1
, pp. 1-23
-
-
Loscher, W.1
Klotz, U.2
Zimprich, F.3
Schmidt, D.4
-
27
-
-
56349138032
-
Several major antiepileptic drugs are substrates for human P-glycoprotein
-
Luna-Tortos, C., Fedrowitz, M., Loscher, W., 2008. Several major antiepileptic drugs are substrates for human P-glycoprotein. Neuropharmacology 55 (8), 1364-1375.
-
(2008)
Neuropharmacology
, vol.55
, Issue.8
, pp. 1364-1375
-
-
Luna-Tortos, C.1
Fedrowitz, M.2
Loscher, W.3
-
28
-
-
77950949013
-
Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy
-
Luna-Tortos, C., Fedrowitz, M., Loscher, W., 2010. Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy. Neuropharmacology 58, 1019-1032.
-
(2010)
Neuropharmacology
, vol.58
, pp. 1019-1032
-
-
Luna-Tortos, C.1
Fedrowitz, M.2
Loscher, W.3
-
29
-
-
13844299003
-
Significance of MDR1 and multiple drug resistance in refractory human epileptic brain
-
Marchi, N., Hallene, K.L., Kight, K.M., Cucullo, L., Moddel, G., Bingaman, W., Dini, G., Vezzani, A., Janigro, D., 2004. Significance of MDR1 and multiple drug resistance in refractory human epileptic brain. BMC Med. 2, 37.
-
(2004)
BMC Med.
, vol.2
, pp. 37
-
-
Marchi, N.1
Hallene, K.L.2
Kight, K.M.3
Cucullo, L.4
Moddel, G.5
Bingaman, W.6
Dini, G.7
Vezzani, A.8
Janigro, D.9
-
30
-
-
1642523162
-
Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
-
Marzolini, C., Paus, E., Buclin, T., Kim, R.B., 2004. Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin. Pharmacol. Ther. 75 (1), 13-33.
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, Issue.1
, pp. 13-33
-
-
Marzolini, C.1
Paus, E.2
Buclin, T.3
Kim, R.B.4
-
31
-
-
37249003692
-
Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey
-
Ozgon, G.O., Bebek, N., Gul, G., Cine, N., 2008. Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey. Eur. Neurol. 59 (1-2), 67-70.
-
(2008)
Eur. Neurol.
, vol.59
, Issue.1-2
, pp. 67-70
-
-
Ozgon, G.O.1
Bebek, N.2
Gul, G.3
Cine, N.4
-
32
-
-
0037178642
-
P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: Evidence from microdialysis experiments in rats
-
Potschka, H., Fedrowitz, M., Loscher, W., 2002. P-glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats. Neurosci. Lett. 327 (3), 173-176.
-
(2002)
Neurosci. Lett.
, vol.327
, Issue.3
, pp. 173-176
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
33
-
-
3242765938
-
Pharmacoresistance and of expression of multidrug transporter P-glycoprotein in kindled rats
-
DOI 10.1097/01.wnr.0000134840.10390.a4
-
Potschka, H., Volk, H.A., Loscher, W., 2004. Parmacoresistance and expression of multidrug transporter P-glycoprotein in kindled rats. Neuroreport 15 (10), 1657-1661. (Pubitemid 38971189)
-
(2004)
NeuroReport
, vol.15
, Issue.10
, pp. 1657-1661
-
-
Potschka, H.1
Volk, H.A.2
Loscher, W.3
-
34
-
-
30344467212
-
Molecular and cellular mechanisms of pharmacoresistance in epilepsy
-
DOI 10.1093/brain/awh682
-
Remy, S., Beck, H., 2006. Molecular and cellular mechanisms of pharmacoresistance in epilepsy. Brain 129, 18-35. (Pubitemid 43063756)
-
(2006)
Brain
, vol.129
, Issue.1
, pp. 18-35
-
-
Remy, S.1
Beck, H.2
-
35
-
-
20544475805
-
Drug resistance in epilepsy: Putative neurobiologic and clinical mechanisms
-
DOI 10.1111/j.1528-1167.2005.54904.x
-
Schmidt, D., Loscher, W., 2005. Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms. Epilepsia 46 (6), 858-877. (Pubitemid 40847354)
-
(2005)
Epilepsia
, vol.46
, Issue.6
, pp. 858-877
-
-
Schmidt, D.1
Loscher, W.2
-
36
-
-
66849131768
-
New developments in antiepileptic drug resistance: An integrative view
-
Schmidt, D., Loscher, W., 2009. New developments in antiepileptic drug resistance: an integrative view. Epilepsy Curr. 9 (2), 47-52.
-
(2009)
Epilepsy Curr.
, vol.9
, Issue.2
, pp. 47-52
-
-
Schmidt, D.1
Loscher, W.2
-
37
-
-
33745155394
-
ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients
-
DOI 10.2217/14622416.7.4.551
-
Seo, T., Ishitsu, T., Ueda, N., Nakada, N., Yurube, K., Ueda, K., Nakagaa, K., 2006. ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients. Pharmacogenomics 7 (4), 551-561. (Pubitemid 43891412)
-
(2006)
Pharmacogenomics
, vol.7
, Issue.4
, pp. 551-561
-
-
Seo, T.1
Ishitsu, T.2
Ueda, N.3
Nakada, N.4
Yurube, K.5
Ueda, K.6
Nakagawa, K.7
-
38
-
-
33847366654
-
The controversial association of ABCB1 polymorphisms in refractory epilepsy: An analysis of multiple SNPs in an Irish population
-
DOI 10.1016/j.eplepsyres.2006.10.004, PII S0920121106004116
-
Shahwan, A., Murphy, K., Doherty, C., Cavalleri, G.L., Muckian, C., Dicker, P., McCarthy, M., Kinirons, P., Goldstein, D., Delanty, N., 2007. The controversial association of ABCB1 polymorphisms in refractory epilepsy: an analysis of multiple SNPs in an Irish population. Epilepsy Res. 73 (2), 192-198. (Pubitemid 46331873)
-
(2007)
Epilepsy Research
, vol.73
, Issue.2
, pp. 192-198
-
-
Shahwan, A.1
Murphy, K.2
Doherty, C.3
Cavalleri, G.L.4
Muckian, C.5
Dicker, P.6
McCarthy, M.7
Kinirons, P.8
Goldstein, D.9
Delanty, N.10
-
39
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1
-
Siddiqui, A., Kerb, R., Weale, M.E., Brinkmann, U., Smith, A., Goldstein, D.B., Wood, N.W., Sisodiya, S.M., 2003. Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. N. Engl. J. Med. 348 (15), 1442-1448.
-
(2003)
N. Engl. J. Med.
, vol.348
, Issue.15
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
Brinkmann, U.4
Smith, A.5
Goldstein, D.B.6
Wood, N.W.7
Sisodiya, S.M.8
-
40
-
-
33244476694
-
Natural history of treated childhood-onset epilepsy: Prospective, long-term population-based study
-
DOI 10.1093/brain/awh726
-
Sillanpaa, M., Schmidt, D., 2006. Natural history of treated childhood onset epilepsy: prospective, long-term population-based study. Brain 129, 617-624. (Pubitemid 43278224)
-
(2006)
Brain
, vol.129
, Issue.3
, pp. 617-624
-
-
Sillanpaa, M.1
Schmidt, D.2
-
41
-
-
18244365827
-
Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment
-
DOI 10.1111/j.1528-1167.2005.46304.x
-
Sills, G.J., Mohanraj, R., Butler, E., McCrindle, S., Collier, L., Wilson, E.A., Brodie, M.J., 2005. Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment. Epilepsia 46 (5), 643-647. (Pubitemid 40628658)
-
(2005)
Epilepsia
, vol.46
, Issue.5
, pp. 643-647
-
-
Sills, G.J.1
Mohanraj, R.2
Butler, E.3
McCrindle, S.4
Collier, L.5
Wilson, E.A.6
Brodie, M.J.7
-
42
-
-
0037399407
-
Mechanisms of antiepileptic drug resistance
-
Sisodiya, S.M., 2003. Mechanisms of antiepileptic drug resistance. Curr. Opin. Neurol. 16 (2), 197-203.
-
(2003)
Curr. Opin. Neurol.
, vol.16
, Issue.2
, pp. 197-203
-
-
Sisodiya, S.M.1
-
43
-
-
33644905041
-
Vascular colocalization of P-glycoprotein,multidrug-resistance associated protein1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies
-
Sisodiya, S.M., Martinian, L., Scheffer, G.L., vanderValk, P., Scheper, R.J., Harding, B.N., Thom, M., 2006. Vascular colocalization of P-glycoprotein,multidrug-resistance associated protein1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies. Neuropathol. Appl. Neurobiol. 32, 51-63.
-
(2006)
Neuropathol. Appl. Neurobiol.
, vol.32
, pp. 51-63
-
-
Sisodiya, S.M.1
Martinian, L.2
Scheffer, G.L.3
VanderValk, P.4
Scheper, R.J.5
Harding, B.N.6
Thom, M.7
-
44
-
-
3543149022
-
Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene
-
DOI 10.1101/gr.1965304
-
Soranzo, N., Cavalleri, G.L., Weale, M.E., Wood, N.W., Depondt, C., Marguerie, R., Sisodiya, S.M., Goldstein, D.B., 2004. Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene. Genome Res. 14 (7), 1333-1344. (Pubitemid 39029230)
-
(2004)
Genome Research
, vol.14
, Issue.7
, pp. 1333-1344
-
-
Soranzo, N.1
Cavalleri, G.L.2
Weale, M.E.3
Wood, N.W.4
Depondt, C.5
Marguerie, R.6
Sisodiya, S.M.7
Goldstein, D.B.8
-
45
-
-
0036667956
-
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
-
DOI 10.1097/00008571-200208000-00004
-
Tang, K., Ngoi, S.M., Gwee, P.C., Chua, J.M., Lee, E.J., Chong, S.S., Lee, C.G., 2002. Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 transporter gene locus in three ethnic Asian populations. Pharmacogenetics 12 (6), 437-450. (Pubitemid 34913526)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.6
, pp. 437-450
-
-
Tang, K.1
Ngoi, S.-M.2
Gwee, P.-C.3
Chua, J.M.Z.4
Lee, E.J.D.5
Chong, S.S.6
Lee, C.G.L.7
-
46
-
-
0028895740
-
MDR1 gene expression in brain of patients with medically intractable epilepsy
-
Tishler, D.M., Weinberg, K.I., Hinton, D.R., Barbaro, N., Annett, G. M., Raffel, C., 1995. MDR1 gene expression in brain of patients with medically intractable epilepsy. Epilepsia 36 (1), 1-6.
-
(1995)
Epilepsia
, vol.36
, Issue.1
, pp. 1-6
-
-
Tishler, D.M.1
Weinberg, K.I.2
Hinton, D.R.3
Barbaro, N.4
Annett, G.M.5
Raffel, C.6
-
47
-
-
69949133732
-
Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population
-
Vahab, S.A., Sen, S., Ravindran, N., Mony, S., Mathew, A., Vijayan, N., Nayak, G., Bhaskaranand, N., Banerjee, M., Satyamoorthy, K., 2009. Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population. Drug Metab. Pharmacokinet. 24 (3), 255-260.
-
(2009)
Drug Metab. Pharmacokinet.
, vol.24
, Issue.3
, pp. 255-260
-
-
Vahab, S.A.1
Sen, S.2
Ravindran, N.3
Mony, S.4
Mathew, A.5
Vijayan, N.6
Nayak, G.7
Bhaskaranand, N.8
Banerjee, M.9
Satyamoorthy, K.10
-
48
-
-
27244436425
-
Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats
-
DOI 10.1111/j.1528-1167.2005.00250.x
-
van Vliet, E.A., Redeker, S., Aronica, E., Edelbroek, P.M., Gorter, J.A., 2005. Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats. Epilepsia 46, 1569-1580. (Pubitemid 44921930)
-
(2005)
Epilepsia
, vol.46
, Issue.10
, pp. 1569-1580
-
-
Van Vliet, E.A.1
Redeker, S.2
Aronica, E.3
Edelbroek, P.M.4
Gorter, J.A.5
-
49
-
-
4544271508
-
Expression of multidrug transporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy
-
Vogelgesang, S., Kunert-Keil, C., Cascorbi, I., Mosyagin, I., Schroder, E., Runge, U., Jedlitschky, G., Kroemer, H.K., Oertel, J., Gaab, M.R., Pahnke, J., Walker, L.C., Warzok, R.W., 2004. Expression of multidrug transporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy. Clin. Neuropathol. 23 (5), 223-231.
-
(2004)
Clin. Neuropathol.
, vol.23
, Issue.5
, pp. 223-231
-
-
Vogelgesang, S.1
Kunert-Keil, C.2
Cascorbi, I.3
Mosyagin, I.4
Schroder, E.5
Runge, U.6
Jedlitschky, G.7
Kroemer, H.K.8
Oertel, J.9
Gaab, M.R.10
Pahnke, J.11
Walker, L.C.12
Warzok, R.W.13
-
50
-
-
0346729785
-
Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures
-
DOI 10.1016/j.neuroscience.2003.10.012
-
Volk, H.A., Burkhardt, K., Potschka, H., Chen, J., Becker, A., Loscher, W., 2004. Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures. Neuroscience 123 (3), 751-759. (Pubitemid 38045412)
-
(2004)
Neuroscience
, vol.123
, Issue.3
, pp. 751-759
-
-
Volk, H.A.1
Burkhardt, K.2
Potschka, H.3
Chen, J.4
Becker, A.5
Loscher, W.6
-
51
-
-
0141519420
-
Interaction of antiepileptic drugs with human P-glycoprotein in vitro
-
Weiss, J., Kerpen, C.J., Lindenmaier, H., Dormann, S.M., Haefeli, W. E., 2003. Interaction of antiepileptic drugs with human P-glycoprotein in vitro. J. Pharmacol. Exp. Ther. 307 (1), 262-267.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.307
, Issue.1
, pp. 262-267
-
-
Weiss, J.1
Kerpen, C.J.2
Lindenmaier, H.3
Dormann, S.M.4
Haefeli, W.E.5
-
52
-
-
4644305242
-
Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy
-
Zimprich, F., Sunder-Plassmann, R., Stogmann, E., Gleiss, A., Dal-Bianco, A., Zimprich, A., Plumer, S., Baumgartner, C., Mannhalter, C., 2004. Association of an ABCB1 gene haplotype with phamacoresistance in temporal lobe epilepsy. Neruology 63 (6), 1087-1089. (Pubitemid 39287922)
-
(2004)
Neurology
, vol.63
, Issue.6
, pp. 1087-1089
-
-
Zimprich, F.1
Sunder-Plassmann, R.2
Stogmann, E.3
Gleiss, A.4
Dal-Bianco, A.5
Zimprich, A.6
Plumer, S.7
Baumgartner, C.8
Mannhalter, C.9
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