Role of loop dynamics in thermal stability of mesophilic and thermophilic adenylosuccinate synthetase: A molecular dynamics and normal mode analysis study

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1814, Issue 5, 2011, Pages 630-637

  Vemparala, Satyavani ^a   Mehrotra, Sonali ^b,c   Balaram, Hemalatha ^b  

^a INSTITUTE OF MATHEMATICAL SCIENCES   (India)

^b JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

^c ReaMetrix India Pvt Ltd   (India)

Author keywords

Enzyme catalysis; Loop dynamics; MD simulations; Normal mode analysis

Indexed keywords

ADENYLOSUCCINATE SYNTHASE;

ARTICLE; CATALYSIS; COMPARATIVE STUDY; ESCHERICHIA COLI; HIGH TEMPERATURE; LIGAND BINDING; MESOPHILE; MOLECULAR DYNAMICS; NONHUMAN; NORMAL MODE ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY; PROTEIN STRUCTURE; PYROCOCCUS HORIKOSHII; SIMULATION; THERMOPHILE; THERMOSTABILITY;

ADENYLOSUCCINATE SYNTHASE; ENZYME STABILITY; ESCHERICHIA COLI; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, SECONDARY; PYROCOCCUS HORIKOSHII; TEMPERATURE;

EID: 79955610051     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.03.012     Document Type: Article

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