IMP alone organizes the active site of adenylosuccinate synthetase from Escherichia coli

Journal of Biological Chemistry

Volumn 277, Issue 8, 2002, Pages 5970-5976

  Hou, Zhenglin ^a,c   Wang, Wenyan ^b   Fromm, Herbert J ^a   Honzatko, Richard B ^b,c  

^a IOWA STATE UNIVERSITY   (United States)

^b PIONEER HI BRED INTERNATIONAL INC   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CRYSTAL STRUCTURE; ESCHERICHIA COLI;

LIGAND BINDING SYNERGISM;

ENZYMES;

ADENYLOSUCCINATE SYNTHASE; HADACIDIN; INOSINE PHOSPHATE; MAGNESIUM ION; PYROPHOSPHATE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL;

ADENYLOSUCCINATE SYNTHASE; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; GLYCINE; GUANOSINE TRIPHOSPHATE; INOSINE MONOPHOSPHATE; MODELS, MOLECULAR; PROTEIN CONFORMATION;

ESCHERICHIA COLI;

EID: 0037155194     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M109561200     Document Type: Article

References (35)