메뉴 건너뛰기




Volumn 12, Issue 5, 2011, Pages 765-773

Transplacental transfer of immunosuppressants and biologics used for the treatment of inflammatory bowel disease

Author keywords

Adalimumab; Azathioprine; Inflammatory bowel disease; Infliximab; Mercaptopurine; Methotrexate; Pregnancy

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; ADALIMUMAB; CERTOLIZUMAB PEGOL; CORTICOSTEROID; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; METHOTREXATE; MONOCLONAL ANTIBODY; STEROID;

EID: 79955601056     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920111795470903     Document Type: Review
Times cited : (36)

References (108)
  • 1
    • 33745217631 scopus 로고    scopus 로고
    • Designing pregnancy centered medications: Drugs which do not cross the human placenta
    • Gedeon, C.; Koren, G. Designing pregnancy centered medications: drugs which do not cross the human placenta. Placenta, 2006, 27(8), 861-868.
    • (2006) Placenta , vol.27 , Issue.8 , pp. 861-868
    • Gedeon, C.1    Koren, G.2
  • 2
    • 0031593467 scopus 로고    scopus 로고
    • Review article: The management of inflammatory bowel disease during pregnancy
    • Subhani, J.M.; Hamiliton, M.I. Review article: The management of inflammatory bowel disease during pregnancy. Aliment. Pharmacol. Ther., 1998, 12(11), 1039-1053.
    • (1998) Aliment. Pharmacol. Ther. , vol.12 , Issue.11 , pp. 1039-1053
    • Subhani, J.M.1    Hamiliton, M.I.2
  • 3
    • 0032877279 scopus 로고    scopus 로고
    • Treating inflammatory bowel disease during pregnancy: Risks and safety of drug therapy
    • Connell, W.; Miller, A. Treating inflammatory bowel disease during pregnancy: risks and safety of drug therapy. Drug Saf., 1999, 21(4), 311-323.
    • (1999) Drug Saf. , vol.21 , Issue.4 , pp. 311-323
    • Connell, W.1    Miller, A.2
  • 4
    • 0033863319 scopus 로고    scopus 로고
    • Pregnancy, fertility, and disease course in patients with Crohn's disease and ulcerative colitis
    • Munkholm, P. Pregnancy, fertility, and disease course in patients with Crohn's disease and ulcerative colitis. Eur. J. Intern. Med., 2000, 11(4), 215-221.
    • (2000) Eur. J. Intern. Med. , vol.11 , Issue.4 , pp. 215-221
    • Munkholm, P.1
  • 5
    • 0034782684 scopus 로고    scopus 로고
    • Inflammatory bowel disease and pregnancy
    • Katz, J.A.; Pore, G. Inflammatory bowel disease and pregnancy. Inflamm. Bowel Dis., 2001, 7(2), 146-157.
    • (2001) Inflamm. Bowel Dis. , vol.7 , Issue.2 , pp. 146-157
    • Katz, J.A.1    Pore, G.2
  • 6
    • 0034883113 scopus 로고    scopus 로고
    • Fertility and pregnancy in inflammatory bowel disease
    • Alstead, E. Fertility and pregnancy in inflammatory bowel disease. World J. Gastroenterol., 2001, 7(4), 455-459.
    • (2001) World J. Gastroenterol. , vol.7 , Issue.4 , pp. 455-459
    • Alstead, E.1
  • 7
    • 0036147244 scopus 로고    scopus 로고
    • Inflammatory bowel disease in pregnancy
    • Alstead, E.M. Inflammatory bowel disease in pregnancy. Postgrad. Med. J., 2002, 78(915), 23-26.
    • (2002) Postgrad. Med. J. , vol.78 , Issue.915 , pp. 23-26
    • Alstead, E.M.1
  • 8
    • 0036935053 scopus 로고    scopus 로고
    • Inflammatory bowel disease and pregnancy
    • Lamah, M.; Scott, H.J. Inflammatory bowel disease and pregnancy. Int. J. Colorectal Dis., 2002, 17(4), 216-222.
    • (2002) Int. J. Colorectal Dis. , vol.17 , Issue.4 , pp. 216-222
    • Lamah, M.1    Scott, H.J.2
  • 9
    • 0037302593 scopus 로고    scopus 로고
    • Inflammatory bowel disease in pregnancy
    • Alstead, E.M.; Nelson-Piercy, C. Inflammatory bowel disease in pregnancy. Gut, 2003, 52(2), 159-161.
    • (2003) Gut , vol.52 , Issue.2 , pp. 159-161
    • Alstead, E.M.1    Nelson-Piercy, C.2
  • 10
    • 0037337146 scopus 로고    scopus 로고
    • Inflammatory bowel disease in pregnancy
    • Kane, S. Inflammatory bowel disease in pregnancy. Gastroenterol. Clin. North Am., 2003, 32(1), 323-340.
    • (2003) Gastroenterol. Clin. North Am. , vol.32 , Issue.1 , pp. 323-340
    • Kane, S.1
  • 11
    • 2942624071 scopus 로고    scopus 로고
    • Medical management of the pregnant patient with inflammatory bowel disease
    • Steinlauf, A.F.; Present, D.H. Medical management of the pregnant patient with inflammatory bowel disease. Gastroenterol. Clin. North Am., 2004, 33(2), 361-385.
    • (2004) Gastroenterol. Clin. North Am. , vol.33 , Issue.2 , pp. 361-385
    • Steinlauf, A.F.1    Present, D.H.2
  • 12
    • 4444245316 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Management issues during pregnancy
    • Ferrero, S.; Ragni, N. Inflammatory bowel disease: management issues during pregnancy. Arch. Gynecol. Obstet., 2004, 270(2), 79-85.
    • (2004) Arch. Gynecol. Obstet. , vol.270 , Issue.2 , pp. 79-85
    • Ferrero, S.1    Ragni, N.2
  • 13
    • 3042550039 scopus 로고    scopus 로고
    • Pregnancy and inflammatory bowel disease
    • Katz, J.A. Pregnancy and inflammatory bowel disease. Curr. Opin. Gastroenterol., 2004, 20(4), 328-332.
    • (2004) Curr. Opin. Gastroenterol. , vol.20 , Issue.4 , pp. 328-332
    • Katz, J.A.1
  • 14
    • 25444521064 scopus 로고    scopus 로고
    • The use of medications for inflammatory bowel disease during pregnancy and nursing
    • Sauk, J.; Kane, S. The use of medications for inflammatory bowel disease during pregnancy and nursing. Expert Opin. Pharmacother., 2005, 6(11), 1833-1839.
    • (2005) Expert Opin. Pharmacother. , vol.6 , Issue.11 , pp. 1833-1839
    • Sauk, J.1    Kane, S.2
  • 15
    • 33745757123 scopus 로고    scopus 로고
    • American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy
    • Mahadevan, U.; Kane, S. American gastroenterological association institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology, 2006, 131(1), 283-311.
    • (2006) Gastroenterology , vol.131 , Issue.1 , pp. 283-311
    • Mahadevan, U.1    Kane, S.2
  • 16
    • 34548684991 scopus 로고    scopus 로고
    • Drug therapy for inflammatory bowel disease in pregnancy and the puerperium
    • Moffatt, D.C.; Bernstein, C.N. Drug therapy for inflammatory bowel disease in pregnancy and the puerperium. Best Pract. Res. Clin. Gastroenterol., 2007, 21(5), 835-847.
    • (2007) Best Pract. Res. Clin. Gastroenterol. , vol.21 , Issue.5 , pp. 835-847
    • Moffatt, D.C.1    Bernstein, C.N.2
  • 18
    • 36049052000 scopus 로고    scopus 로고
    • Common errors in the management of outpatients with inflammatory bowel disease
    • Gisbert, J.P.; Gomollon, F. [Common errors in the management of outpatients with inflammatory bowel disease]. Gastroenterol. Hepatol., 2007, 30(8), 469-486.
    • (2007) Gastroenterol. Hepatol. , vol.30 , Issue.8 , pp. 469-486
    • Gisbert, J.P.1    Gomollon, F.2
  • 19
    • 41149084587 scopus 로고    scopus 로고
    • Management of inflammatory bowel disease in the pregnant patient
    • Habal, F.M.; Ravindran, N.C. Management of inflammatory bowel disease in the pregnant patient. World J. Gastroenterol., 2008, 14(9), 1326-1332.
    • (2008) World J. Gastroenterol. , vol.14 , Issue.9 , pp. 1326-1332
    • Habal, F.M.1    Ravindran, N.C.2
  • 21
    • 60849100223 scopus 로고    scopus 로고
    • Inflammatory bowel disease and pregnancy: Evidence, uncertainty and patient decision-making
    • Habal, F.M.; Kapila, V. Inflammatory bowel disease and pregnancy: evidence, uncertainty and patient decision-making. Can. J. Gastroenterol., 2009, 23(1), 49-53.
    • (2009) Can. J. Gastroenterol. , vol.23 , Issue.1 , pp. 49-53
    • Habal, F.M.1    Kapila, V.2
  • 22
    • 77950674533 scopus 로고    scopus 로고
    • Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding
    • Gisbert, J.P. Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding. Inflamm. Bowel Dis., 2010, 16(5), 881-895.
    • (2010) Inflamm. Bowel Dis. , vol.16 , Issue.5 , pp. 881-895
    • Gisbert, J.P.1
  • 23
    • 34249824261 scopus 로고    scopus 로고
    • A meta-analysis on the influence of inflammatory bowel disease on pregnancy
    • Cornish, J.; Tan, E.; Teare, J.; Teoh, T.G.; Rai, R.; Clark, S.K.; Tekkis, P.P. A meta-analysis on the influence of inflammatory bowel disease on pregnancy. Gut, 2007, 56(6), 830-837.
    • (2007) Gut , vol.56 , Issue.6 , pp. 830-837
    • Cornish, J.1    Tan, E.2    Teare, J.3    Teoh, T.G.4    Rai, R.5    Clark, S.K.6    Tekkis, P.P.7
  • 24
    • 0030721658 scopus 로고    scopus 로고
    • Pregnancy outcomes in women with inflammatory bowel disease--a population-based cohort study
    • Kornfeld, D.; Cnattingius, S.; Ekbom, A. Pregnancy outcomes in women with inflammatory bowel disease--a population-based cohort study. Am. J. Obstet. Gynecol., 1997, 177(4), 942-946.
    • (1997) Am. J. Obstet. Gynecol. , vol.177 , Issue.4 , pp. 942-946
    • Kornfeld, D.1    Cnattingius, S.2    Ekbom, A.3
  • 25
    • 33746137475 scopus 로고    scopus 로고
    • Fertility and pregnancy in the patient with inflammatory bowel disease
    • Mahadevan, U. Fertility and pregnancy in the patient with inflammatory bowel disease. Gut, 2006, 55(8), 1198-1206.
    • (2006) Gut , vol.55 , Issue.8 , pp. 1198-1206
    • Mahadevan, U.1
  • 28
    • 0028945203 scopus 로고
    • Placental transfer of drugs administered to the mother
    • Pacifici, G.M.; Nottoli, R. Placental transfer of drugs administered to the mother. Clin. Pharmacokinet., 1995, 28(3), 235-269.
    • (1995) Clin. Pharmacokinet. , vol.28 , Issue.3 , pp. 235-269
    • Pacifici, G.M.1    Nottoli, R.2
  • 29
    • 3042725709 scopus 로고    scopus 로고
    • Drug transfer and metabolism by the human placenta
    • Syme, M.R.; Paxton, J.W.; Keelan, J.A. Drug transfer and metabolism by the human placenta. Clin. Pharmacokinet., 2004, 43(8), 487-514.
    • (2004) Clin. Pharmacokinet. , vol.43 , Issue.8 , pp. 487-514
    • Syme, M.R.1    Paxton, J.W.2    Keelan, J.A.3
  • 30
    • 0023969753 scopus 로고
    • The significance of plasma protein binding on the fetal/maternal distribution of drugs at steady-state
    • Hill, M.D.; Abramson, F.P. The significance of plasma protein binding on the fetal/maternal distribution of drugs at steady-state. Clin. Pharmacokinet., 1988, 14(3), 156-170.
    • (1988) Clin. Pharmacokinet. , vol.14 , Issue.3 , pp. 156-170
    • Hill, M.D.1    Abramson, F.P.2
  • 31
    • 0021236578 scopus 로고
    • Low molecular weight heparin (PK 10169) does not cross the placenta during the second trimester of pregnancy study by direct fetal blood sampling under ultrasound
    • Forestier, F.; Daffos, F.; Capella-Pavlovsky, M. Low molecular weight heparin (PK 10169) does not cross the placenta during the second trimester of pregnancy study by direct fetal blood sampling under ultrasound. Thromb. Res., 1984, 34(6), 557-560.
    • (1984) Thromb. Res. , vol.34 , Issue.6 , pp. 557-560
    • Forestier, F.1    Daffos, F.2    Capella-Pavlovsky, M.3
  • 32
    • 0021013045 scopus 로고
    • Alpha 1-acid glycoprotein and binding of basic drugs
    • Paxton, J.W. Alpha 1-acid glycoprotein and binding of basic drugs. Methods Find. Exp. Clin. Pharmacol., 1983, 5(9), 635-648.
    • (1983) Methods Find. Exp. Clin. Pharmacol. , vol.5 , Issue.9 , pp. 635-648
    • Paxton, J.W.1
  • 33
    • 0019538149 scopus 로고
    • Molecular aspects of ligand binding to serum albumin
    • Kragh-Hansen, U. Molecular aspects of ligand binding to serum albumin. Pharmacol. Rev., 1981, 33(1), 17-53.
    • (1981) Pharmacol. Rev. , vol.33 , Issue.1 , pp. 17-53
    • Kragh-Hansen, U.1
  • 34
    • 0344435242 scopus 로고    scopus 로고
    • Techniques to study human placental transport
    • Sastry, B.V. Techniques to study human placental transport. Adv. Drug Deliv. Rev., 1999, 38(1), 17-39.
    • (1999) Adv. Drug Deliv. Rev. , vol.38 , Issue.1 , pp. 17-39
    • Sastry, B.V.1
  • 35
    • 0030225385 scopus 로고    scopus 로고
    • Ontogeny of glucose transport systems in the placenta and its progenitor tissues
    • Hahn, T.; Desoye, G. Ontogeny of glucose transport systems in the placenta and its progenitor tissues. Early Pregnancy, 1996, 2(3), 168-182.
    • (1996) Early Pregnancy , vol.2 , Issue.3 , pp. 168-182
    • Hahn, T.1    Desoye, G.2
  • 36
    • 0028796853 scopus 로고
    • Placental amino acid transport
    • Moe, A.J. Placental amino acid transport. Am. J. Physiol., 1995, 268(6 Pt 1), C1321-1331.
    • (1995) Am. J. Physiol. , vol.268 , Issue.6 PART 1
    • Moe, A.J.1
  • 38
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M.M.; Pastan, I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem., 1993, 62, 385-427.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 39
    • 0033943307 scopus 로고    scopus 로고
    • Placental transporters relevant to drug distribution across the maternalfetal interface
    • Ganapathy, V.; Prasad, P.D.; Ganapathy, M.E.; Leibach, F.H. Placental transporters relevant to drug distribution across the maternalfetal interface. J. Pharmacol. Exp. Ther., 2000, 294(2), 413-420.
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , Issue.2 , pp. 413-420
    • Ganapathy, V.1    Prasad, P.D.2    Ganapathy, M.E.3    Leibach, F.H.4
  • 40
    • 0032129118 scopus 로고    scopus 로고
    • Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice
    • Lankas, G.R.; Wise, L.D.; Cartwright, M.E.; Pippert, T.; Umbenhauer, D.R. Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice. Reprod. Toxicol., 1998, 12(4), 457-463.
    • (1998) Reprod. Toxicol. , vol.12 , Issue.4 , pp. 457-463
    • Lankas, G.R.1    Wise, L.D.2    Cartwright, M.E.3    Pippert, T.4    Umbenhauer, D.R.5
  • 41
    • 0032701128 scopus 로고    scopus 로고
    • Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure
    • Smit, J.W.; Huisman, M.T.; van Tellingen, O.; Wiltshire, H.R.; Schinkel, A.H. Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure. J. Clin. Invest., 1999, 104(10), 1441-1447.
    • (1999) J. Clin. Invest. , vol.104 , Issue.10 , pp. 1441-1447
    • Smit, J.W.1    Huisman, M.T.2    van Tellingen, O.3    Wiltshire, H.R.4    Schinkel, A.H.5
  • 42
    • 0344927562 scopus 로고    scopus 로고
    • Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
    • König, J.; Nies, A.T.; Cui, Y.; Leier, I.; Keppler, D. Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim. Biophys. Acta, 1999, 1461(2), 377-394.
    • (1999) Biochim. Biophys. Acta , vol.1461 , Issue.2 , pp. 377-394
    • König, J.1    Nies, A.T.2    Cui, Y.3    Leier, I.4    Keppler, D.5
  • 43
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst, P.; Evers, R.; Kool, M.; Wijnholds, J. A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst., 2000, 92(16), 1295-1302.
    • (2000) J. Natl. Cancer Inst. , vol.92 , Issue.16 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3    Wijnholds, J.4
  • 45
    • 0345299165 scopus 로고    scopus 로고
    • Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells
    • Cui, Y.; König, J.; Buchholz, J.K.; Spring, H.; Leier, I.; Keppler, D. Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. Mol. Pharmacol., 1999, 55(5), 929-937.
    • (1999) Mol. Pharmacol. , vol.55 , Issue.5 , pp. 929-937
    • Cui, Y.1    König, J.2    Buchholz, J.K.3    Spring, H.4    Leier, I.5    Keppler, D.6
  • 46
    • 0014623677 scopus 로고
    • Premature delivery of foetal lambs infused with glucocorticoids
    • Liggins, G.C. Premature delivery of foetal lambs infused with glucocorticoids. J. Endocrinol., 1969, 45(4), 515-523.
    • (1969) J. Endocrinol. , vol.45 , Issue.4 , pp. 515-523
    • Liggins, G.C.1
  • 48
    • 0027980454 scopus 로고
    • Pharmacologic enhancement of fetal lung maturation
    • Ward, R.M. Pharmacologic enhancement of fetal lung maturation. Clin. Perinatol., 1994, 21(3), 523-542.
    • (1994) Clin. Perinatol. , vol.21 , Issue.3 , pp. 523-542
    • Ward, R.M.1
  • 49
    • 0029160288 scopus 로고
    • Scientific basis and therapeutic regimens for use of antenatal glucocorticoids
    • Ballard, P.L.; Ballard, R.A. Scientific basis and therapeutic regimens for use of antenatal glucocorticoids. Am. J. Obstet. Gynecol., 1995, 173(1), 254-262.
    • (1995) Am. J. Obstet. Gynecol. , vol.173 , Issue.1 , pp. 254-262
    • Ballard, P.L.1    Ballard, R.A.2
  • 50
    • 0025232649 scopus 로고
    • The effects of corticosteroid administration before preterm delivery: An overview of the evidence from controlled trials
    • Crowley, P.; Chalmers, I.; Keirse, M.J. The effects of corticosteroid administration before preterm delivery: an overview of the evidence from controlled trials. Br. J. Obstet. Gynaecol., 1990, 97(1), 11-25.
    • (1990) Br. J. Obstet. Gynaecol. , vol.97 , Issue.1 , pp. 11-25
    • Crowley, P.1    Chalmers, I.2    Keirse, M.J.3
  • 51
    • 0022497114 scopus 로고
    • Investigation of the maternal to foetal serum concentration gradient of dexamethasone in the rat
    • Varma, D.R. Investigation of the maternal to foetal serum concentration gradient of dexamethasone in the rat. Br. J. Pharmacol., 1986, 88(4), 815-820.
    • (1986) Br. J. Pharmacol. , vol.88 , Issue.4 , pp. 815-820
    • Varma, D.R.1
  • 52
    • 0034103823 scopus 로고    scopus 로고
    • Effects of cyclosporin at various concentrations on dexamethasone intracellular uptake in multidrug resistant cells
    • Maillefert, J.F.; Duchamp, O.; Solary, E.; Genne, P.; Tavernier, C. Effects of cyclosporin at various concentrations on dexamethasone intracellular uptake in multidrug resistant cells. Ann. Rheum. Dis., 2000, 59(2), 146-148.
    • (2000) Ann. Rheum. Dis. , vol.59 , Issue.2 , pp. 146-148
    • Maillefert, J.F.1    Duchamp, O.2    Solary, E.3    Genne, P.4    Tavernier, C.5
  • 55
    • 0036255563 scopus 로고    scopus 로고
    • Teratogen update: Azathioprine and 6-mercaptopurine
    • Polifka, J.E.; Friedman, J.M. Teratogen update: azathioprine and 6-mercaptopurine. Teratology, 2002, 65(5), 240-261.
    • (2002) Teratology , vol.65 , Issue.5 , pp. 240-261
    • Polifka, J.E.1    Friedman, J.M.2
  • 56
    • 0024425480 scopus 로고
    • Azathioprine, a genotoxic agent to be considered nongenotoxic in man
    • Voogd, C.E. Azathioprine, a genotoxic agent to be considered nongenotoxic in man. Mutat. Res., 1989, 221(2), 133-152.
    • (1989) Mutat. Res. , vol.221 , Issue.2 , pp. 133-152
    • Voogd, C.E.1
  • 57
    • 13844322705 scopus 로고
    • The genetic toxicology of 6-mercaptopurine
    • Mosesso, P.; Palitti, F. The genetic toxicology of 6-mercaptopurine. Mutat. Res., 1993, 296(3), 279-294.
    • (1993) Mutat. Res. , vol.296 , Issue.3 , pp. 279-294
    • Mosesso, P.1    Palitti, F.2
  • 58
    • 0029563783 scopus 로고
    • Effects of immunosuppressive drugs during pregnancy
    • Bermas, B.L.; Hill, J.A. Effects of immunosuppressive drugs during pregnancy. Arthritis Rheum., 1995, 38(12), 1722-1732.
    • (1995) Arthritis Rheum. , vol.38 , Issue.12 , pp. 1722-1732
    • Bermas, B.L.1    Hill, J.A.2
  • 59
    • 0030468663 scopus 로고    scopus 로고
    • Dose-response relationship of teratogenicity and prenatal-toxic risk estimation of 6-mercaptopurine riboside in mice
    • Platzek, T.; Bochert, G. Dose-response relationship of teratogenicity and prenatal-toxic risk estimation of 6-mercaptopurine riboside in mice. Teratog. Carcinog. Mutagen., 1996, 16(3), 169-181.
    • (1996) Teratog. Carcinog. Mutagen. , vol.16 , Issue.3 , pp. 169-181
    • Platzek, T.1    Bochert, G.2
  • 61
    • 0037288486 scopus 로고    scopus 로고
    • Pregnancy in renal transplant recipients
    • Hou, S. Pregnancy in renal transplant recipients. Adv. Ren. Replace. Ther., 2003, 10(1), 40-47.
    • (2003) Adv. Ren. Replace. Ther. , vol.10 , Issue.1 , pp. 40-47
    • Hou, S.1
  • 62
    • 20444483170 scopus 로고    scopus 로고
    • A randomized, double-blind, controlled withdrawal trial in Crohn's disease patients in long-term remission on azathioprine
    • Groupe D'Etude Thérapeutique des Affections Inflammatoires du Tube Digestif
    • Lémann, M.; Mary, J.Y.; Colombel, J.F.; Duclos, B.; Soule, J.C.; Lerebours, E.; Modigliani, R.; Bouhnik, Y.; Groupe D'Etude Thérapeutique des Affections Inflammatoires du Tube Digestif. A randomized, double-blind, controlled withdrawal trial in Crohn's disease patients in long-term remission on azathioprine. Gastroenterology, 2005, 128(7), 1812-1818.
    • (2005) Gastroenterology , vol.128 , Issue.7 , pp. 1812-1818
    • Lémann, M.1    Mary, J.Y.2    Colombel, J.F.3    Duclos, B.4    Soule, J.C.5    Lerebours, E.6    Modigliani, R.7    Bouhnik, Y.8
  • 63
    • 58149136086 scopus 로고    scopus 로고
    • Azathioprine withdrawal in patients with Crohn's disease maintained on prolonged remission: A high risk of relapse
    • Groupe D'Etude Thérapeutique Des Affections Inflammatoires Du Tube Digestif (GETAID)
    • Treton, X.; Bouhnik, Y.; Mary, J.Y.; Colombel, J.F.; Duclos, B.; Soule, J.C.; Lerebours, E.; Cosnes, J.; Lemann, M. Groupe D'Etude Thérapeutique Des Affections Inflammatoires Du Tube Digestif (GETAID). Azathioprine withdrawal in patients with Crohn's disease maintained on prolonged remission: a high risk of relapse. Clin. Gastroenterol. Hepatol., 2009, 7(1), 80-85.
    • (2009) Clin. Gastroenterol. Hepatol. , vol.7 , Issue.1 , pp. 80-85
    • Treton, X.1    Bouhnik, Y.2    Mary, J.Y.3    Colombel, J.F.4    Duclos, B.5    Soule, J.C.6    Lerebours, E.7    Cosnes, J.8    Lemann, M.9
  • 64
    • 34250887694 scopus 로고    scopus 로고
    • Medical therapy and birth outcomes in women with Crohn's disease: What should we tell our patients?
    • Friedman, S. Medical therapy and birth outcomes in women with Crohn's disease: what should we tell our patients? Am. J. Gastroenterol., 2007, 102(7), 1414-1416.
    • (2007) Am. J. Gastroenterol. , vol.102 , Issue.7 , pp. 1414-1416
    • Friedman, S.1
  • 65
    • 0037376898 scopus 로고    scopus 로고
    • Complications of pregnancy and child development after cessation of treatment with 6-mercaptopurine for inflammatory bowel disease
    • Zlatanic, J.; Korelitz, B.I.; Rajapakse, R.; Kim, P.S.; Rubin, S.D.; Baiocco, P.J.; Panagopoulos, G. Complications of pregnancy and child development after cessation of treatment with 6-mercaptopurine for inflammatory bowel disease. J. Clin. Gastroenterol., 2003, 36(4), 303-309.
    • (2003) J. Clin. Gastroenterol. , vol.36 , Issue.4 , pp. 303-309
    • Zlatanic, J.1    Korelitz, B.I.2    Rajapakse, R.3    Kim, P.S.4    Rubin, S.D.5    Baiocco, P.J.6    Panagopoulos, G.7
  • 66
    • 0015925086 scopus 로고
    • Immunosuppression during pregnancy: Transmission of azathioprine and its metabolites from the mother to the fetus
    • Saarikoski, S.; Seppälä, M. Immunosuppression during pregnancy: transmission of azathioprine and its metabolites from the mother to the fetus. Am. J. Obstet. Gynecol., 1973, 115(8), 1100-1106.
    • (1973) Am. J. Obstet. Gynecol. , vol.115 , Issue.8 , pp. 1100-1106
    • Saarikoski, S.1    Seppälä, M.2
  • 67
    • 0035734121 scopus 로고    scopus 로고
    • Continuing therapy for childhood acute lymphoblastic leukaemia: Clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine
    • Estlin, E.J. Continuing therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine. Cancer Treat. Rev., 2001, 27(6), 351-363.
    • (2001) Cancer Treat. Rev. , vol.27 , Issue.6 , pp. 351-363
    • Estlin, E.J.1
  • 68
    • 0028071581 scopus 로고
    • DNA modification induced by 6-mercaptopurine riboside in murine embryos
    • Platzek, T.; Schwabe, R.; Rahm, U.; Bochert, G. DNA modification induced by 6-mercaptopurine riboside in murine embryos. Chem. Biol. Interact., 1994, 93(1), 59-71.
    • (1994) Chem. Biol. Interact. , vol.93 , Issue.1 , pp. 59-71
    • Platzek, T.1    Schwabe, R.2    Rahm, U.3    Bochert, G.4
  • 69
    • 1542618030 scopus 로고    scopus 로고
    • Review of the potential effects of three commonly used antineoplastic and immunosuppressive drugs (cyclophosphamide, azathioprine, doxorubicin on the embryo and placenta)
    • Matalon, S.T.; Ornoy, A.; Lishner, M. Review of the potential effects of three commonly used antineoplastic and immunosuppressive drugs (cyclophosphamide, azathioprine, doxorubicin on the embryo and placenta). Reprod. Toxicol., 2004, 18(2), 219-230.
    • (2004) Reprod. Toxicol. , vol.18 , Issue.2 , pp. 219-230
    • Matalon, S.T.1    Ornoy, A.2    Lishner, M.3
  • 71
    • 2342499810 scopus 로고    scopus 로고
    • Toward a better understanding of methotrexate
    • Kremer, J.M. Toward a better understanding of methotrexate. Arthritis Rheum., 2004, 50(5), 1370-1382.
    • (2004) Arthritis Rheum. , vol.50 , Issue.5 , pp. 1370-1382
    • Kremer, J.M.1
  • 74
    • 30944433773 scopus 로고    scopus 로고
    • Cyclosporine in the treatment of severe attack of ulcerative colitis: A systematic review
    • García-López, S.; Gomollón-García, F.; Pérez-Gisbert, J. Cyclosporine in the treatment of severe attack of ulcerative colitis: a systematic review. Gastroenterol. Hepatol., 2005, 28(10), 607-614.
    • (2005) Gastroenterol. Hepatol. , vol.28 , Issue.10 , pp. 607-614
    • García-López, S.1    Gomollón-García, F.2    Pérez-Gisbert, J.3
  • 75
    • 0023229361 scopus 로고
    • Fulminant ulcerative colitis in late pregnancy and the puerperium
    • Anderson, J.B.; Turner, G.M.; Williamson, R.C. Fulminant ulcerative colitis in late pregnancy and the puerperium. J. R. Soc. Med., 1987, 80(8), 492-494.
    • (1987) J. R. Soc. Med. , vol.80 , Issue.8 , pp. 492-494
    • Anderson, J.B.1    Turner, G.M.2    Williamson, R.C.3
  • 76
    • 0028258495 scopus 로고
    • National transplantation Pregnancy Registry--outcomes of 154 pregnancies in cyclosporine-treated female kidney transplant recipients
    • Armenti, V.T.; Ahlswede, K.M.; Ahlswede, B.A.; Jarrell, B.E.; Moritz, M.J.; Burke, J.F. National transplantation Pregnancy Registry--outcomes of 154 pregnancies in cyclosporine-treated female kidney transplant recipients. Transplantation, 1994, 57(4), 502-506.
    • (1994) Transplantation , vol.57 , Issue.4 , pp. 502-506
    • Armenti, V.T.1    Ahlswede, K.M.2    Ahlswede, B.A.3    Jarrell, B.E.4    Moritz, M.J.5    Burke, J.F.6
  • 78
    • 0035041316 scopus 로고    scopus 로고
    • Pregnancy outcome after cyclosporine therapy during pregnancy: A meta-analysis
    • Bar Oz, B.; Hackman, R.; Einarson, T.; Koren, G. Pregnancy outcome after cyclosporine therapy during pregnancy: a meta-analysis. Transplantation, 2001, 71(8), 1051-1055.
    • (2001) Transplantation , vol.71 , Issue.8 , pp. 1051-1055
    • Bar Oz, B.1    Hackman, R.2    Einarson, T.3    Koren, G.4
  • 79
    • 0025344301 scopus 로고
    • Transplacental passage of cyclosporine after liver transplantation
    • Bourget, P.; Fernandez, H.; Bismuth, H.; Papiernik, E. Transplacental passage of cyclosporine after liver transplantation. Transplantation, 1990, 49(3), 663.
    • (1990) Transplantation , vol.49 , Issue.3 , pp. 663
    • Bourget, P.1    Fernandez, H.2    Bismuth, H.3    Papiernik, E.4
  • 82
    • 33845419436 scopus 로고    scopus 로고
    • Systematic review: Infliximab therapy in ulcerative colitis
    • Gisbert, J.P.; González-Lama, J.; Maté, J. Systematic review: Infliximab therapy in ulcerative colitis. Aliment. Pharmacol. Ther., 2007, 25(1), 19-37.
    • (2007) Aliment. Pharmacol. Ther. , vol.25 , Issue.1 , pp. 19-37
    • Gisbert, J.P.1    González-Lama, J.2    Maté, J.3
  • 83
    • 24144456554 scopus 로고    scopus 로고
    • Infections associated with tumor necrosis factor-alpha antagonists
    • Rychly, D.J.; DiPiro, J.T. Infections associated with tumor necrosis factor-alpha antagonists. Pharmacotherapy, 2005, 25(9), 1181-1192.
    • (2005) Pharmacotherapy , vol.25 , Issue.9 , pp. 1181-1192
    • Rychly, D.J.1    DiPiro, J.T.2
  • 85
    • 11144266570 scopus 로고    scopus 로고
    • Outcome of pregnancy in women receiving infliximab for the treatment of Crohn's disease and rheumatoid arthritis
    • Katz, J.A.; Antoni, C.; Keenan, G.F.; Smith, D.E.; Jacobs, S.J.; Lichtenstein, G.R. Outcome of pregnancy in women receiving infliximab for the treatment of Crohn's disease and rheumatoid arthritis. Am. J. Gastroenterol., 2004, 99(12), 2385-2392.
    • (2004) Am. J. Gastroenterol. , vol.99 , Issue.12 , pp. 2385-2392
    • Katz, J.A.1    Antoni, C.2    Keenan, G.F.3    Smith, D.E.4    Jacobs, S.J.5    Lichtenstein, G.R.6
  • 86
    • 55649117701 scopus 로고    scopus 로고
    • Efficacy and safety of adalimumab for the treatment of Crohn's disease in adults
    • Colombel, J.F. Efficacy and safety of adalimumab for the treatment of Crohn's disease in adults. Expert Rev. Gastroenterol. Hepatol., 2008, 2(2), 163-176.
    • (2008) Expert Rev. Gastroenterol. Hepatol. , vol.2 , Issue.2 , pp. 163-176
    • Colombel, J.F.1
  • 87
    • 10944225166 scopus 로고    scopus 로고
    • Adalimumab: Human recombinant immunoglobulin g1 anti-tumor necrosis factor monoclonal antibody
    • Baker, D.E. Adalimumab: human recombinant immunoglobulin g1 anti-tumor necrosis factor monoclonal antibody. Rev. Gastroenterol. Disord., 2004, 4(4), 196-210.
    • (2004) Rev. Gastroenterol. Disord. , vol.4 , Issue.4 , pp. 196-210
    • Baker, D.E.1
  • 88
    • 65649134752 scopus 로고    scopus 로고
    • A safety assessment of tumor necrosis factor antagonists during pregnancy: A review of the Food and Drug Administration database
    • Carter, J.D.; Ladhani, A.; Ricca, L.R.; Valeriano, J.; Vasey, F.B. A safety assessment of tumor necrosis factor antagonists during pregnancy: a review of the Food and Drug Administration database. J. Rheumatol., 2009, 36(3), 635-641.
    • (2009) J. Rheumatol. , vol.36 , Issue.3 , pp. 635-641
    • Carter, J.D.1    Ladhani, A.2    Ricca, L.R.3    Valeriano, J.4    Vasey, F.B.5
  • 89
    • 34047178478 scopus 로고    scopus 로고
    • Pregnancy in rheumatology patients exposed to anti-tumour necrosis factor (TNF)-alpha therapy
    • Roux, C.H.; Brocq, O.; Breuil, V.; Albert, C.; Euller-Ziegler, L. Pregnancy in rheumatology patients exposed to anti-tumour necrosis factor (TNF)-alpha therapy. Rheumatology (Oxford), 2007, 46(4), 695-698.
    • (2007) Rheumatology (Oxford) , vol.46 , Issue.4 , pp. 695-698
    • Roux, C.H.1    Brocq, O.2    Breuil, V.3    Albert, C.4    Euller-Ziegler, L.5
  • 91
    • 23344440960 scopus 로고    scopus 로고
    • Adalimumab use in pregnancy
    • Vesga, L.; Terdiman, J.P.; Mahadevan, U. Adalimumab use in pregnancy. Gut, 2005, 54(6), 890.
    • (2005) Gut , vol.54 , Issue.6 , pp. 890
    • Vesga, L.1    Terdiman, J.P.2    Mahadevan, U.3
  • 92
    • 33747439637 scopus 로고    scopus 로고
    • Successful use of adalimumab (Humira) for Crohn's disease in pregnancy
    • Mishkin, D.S.; Van Deinse, W.; Becker, J.M.; Farraye, F.A. Successful use of adalimumab (Humira) for Crohn's disease in pregnancy. Inflamm. Bowel Dis., 2006, 12(8), 827-828.
    • (2006) Inflamm. Bowel Dis. , vol.12 , Issue.8 , pp. 827-828
    • Mishkin, D.S.1    van Deinse, W.2    Becker, J.M.3    Farraye, F.A.4
  • 93
    • 33751516098 scopus 로고    scopus 로고
    • The successful use of adalimumab to treat active Crohn's disease of an ileoanal pouch during pregnancy
    • Coburn, L.A.; Wise, P.E.; Schwartz, D.A. The successful use of adalimumab to treat active Crohn's disease of an ileoanal pouch during pregnancy. Dig. Dis. Sci., 2006, 51(11), 2045-2047.
    • (2006) Dig. Dis. Sci. , vol.51 , Issue.11 , pp. 2045-2047
    • Coburn, L.A.1    Wise, P.E.2    Schwartz, D.A.3
  • 97
    • 33748971878 scopus 로고    scopus 로고
    • Immunoglobulins--basic considerations
    • Mix, E.; Goertsches, R.; Zett, U.K. Immunoglobulins--basic considerations. J. Neurol., 2006, 253(Suppl 5), V9-V17.
    • (2006) J. Neurol. , vol.253 , Issue.SUPPL. 5
    • Mix, E.1    Goertsches, R.2    Zett, U.K.3
  • 98
    • 0033064703 scopus 로고    scopus 로고
    • Dynamics of immunoglobulins at the feto-maternal interface
    • Saji, F.; Samejima, Y.; Kamiura, S.; Koyama, M. Dynamics of immunoglobulins at the feto-maternal interface. Rev. Reprod., 1999, 4(2), 81-89.
    • (1999) Rev. Reprod. , vol.4 , Issue.2 , pp. 81-89
    • Saji, F.1    Samejima, Y.2    Kamiura, S.3    Koyama, M.4
  • 99
    • 23444462666 scopus 로고    scopus 로고
    • A novel Fc gamma R-defined, IgG-containing organelle in placental endothelium
    • Takizawa, T.; Anderson, C.L.; Robinson, J.M. A novel Fc gamma R-defined, IgG-containing organelle in placental endothelium. J. Immunol., 2005, 175(4), 2331-2339.
    • (2005) J. Immunol. , vol.175 , Issue.4 , pp. 2331-2339
    • Takizawa, T.1    Anderson, C.L.2    Robinson, J.M.3
  • 100
    • 70049090959 scopus 로고    scopus 로고
    • An interspecies comparison of placental antibody transfer: New insights into developmental toxicity testing of monoclonal antibodies
    • Pentsuk, N.; van der Laan, J.W. An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies. Birth Defects Res. B Dev. Reprod. Toxicol., 2009, 86(4), 328-344.
    • (2009) Birth Defects Res. B Dev. Reprod. Toxicol. , vol.86 , Issue.4 , pp. 328-344
    • Pentsuk, N.1    van der Laan, J.W.2
  • 101
    • 0037708020 scopus 로고    scopus 로고
    • Ex vivo human placenta models: Transport of immunoglobulin G and its subclasses
    • Malek, A. Ex vivo human placenta models: transport of immunoglobulin G and its subclasses. Vaccine, 2003, 21(24), 3362-3364.
    • (2003) Vaccine , vol.21 , Issue.24 , pp. 3362-3364
    • Malek, A.1
  • 102
    • 0028061347 scopus 로고
    • A major histocompatibility complex class I-like Fc receptor cloned from human placenta: Possible role in transfer of immunoglobulin G from mother to fetus
    • Story, C.M.; Mikulska, J.E.; Simister, N.E. A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus. J. Exp. Med., 1994, 180(6), 2377-2381.
    • (1994) J. Exp. Med. , vol.180 , Issue.6 , pp. 2377-2381
    • Story, C.M.1    Mikulska, J.E.2    Simister, N.E.3
  • 103
    • 34548229364 scopus 로고    scopus 로고
    • FcRn: The neonatal Fc receptor comes of age
    • Roopenian, D.C.; Akilesh, S. FcRn: the neonatal Fc receptor comes of age. Nat. Rev. Immunol., 2007, 7(9), 715-725.
    • (2007) Nat. Rev. Immunol. , vol.7 , Issue.9 , pp. 715-725
    • Roopenian, D.C.1    Akilesh, S.2
  • 104
    • 0027270512 scopus 로고
    • Immunoglobulin G binding sites on the human foetal intestine: A possible mechanism for the passive transfer of immunity from mother to infant
    • Israel, E.J.; Simister, N.; Freiberg, E.; Caplan, A.; Walker, W.A. Immunoglobulin G binding sites on the human foetal intestine: a possible mechanism for the passive transfer of immunity from mother to infant. Immunology, 1993, 79(1), 77-81.
    • (1993) Immunology , vol.79 , Issue.1 , pp. 77-81
    • Israel, E.J.1    Simister, N.2    Freiberg, E.3    Caplan, A.4    Walker, W.A.5
  • 105
    • 0029082330 scopus 로고
    • Cytotrophoblast cells: A barrier to maternofetal transmission of passive immunity
    • Bright, N.A.; Ockleford, C.D. Cytotrophoblast cells: a barrier to maternofetal transmission of passive immunity. J. Histochem. Cytochem., 1995, 43(9), 933-944.
    • (1995) J. Histochem. Cytochem. , vol.43 , Issue.9 , pp. 933-944
    • Bright, N.A.1    Ockleford, C.D.2
  • 106
    • 0038159545 scopus 로고    scopus 로고
    • An immunohistochemical study of the secretory immune system in human fetal membranes and decidua of the first trimester of pregnancy
    • Gurevich, P.; Elhayany, A.; Ben-Hur, H.; Moldavsky, M.; Szvalb, S.; Zandbank, J.; Shperling, I.; Zusman, I. An immunohistochemical study of the secretory immune system in human fetal membranes and decidua of the first trimester of pregnancy. Am. J. Reprod. Immunol., 2003, 50(1), 13-19.
    • (2003) Am. J. Reprod. Immunol. , vol.50 , Issue.1 , pp. 13-19
    • Gurevich, P.1    Elhayany, A.2    Ben-Hur, H.3    Moldavsky, M.4    Szvalb, S.5    Zandbank, J.6    Shperling, I.7    Zusman, I.8
  • 107
    • 63849149666 scopus 로고    scopus 로고
    • Placental transfer of the anti-TNF antibody TN3 in rats: Comparison of immunoglobulin G1 and pegylated Fab versions
    • Stephens, P.; Nesbitt, A.; Foulkes, R. Placental transfer of the anti-TNF antibody TN3 in rats: comparison of immunoglobulin G1 and pegylated Fab versions. Gut, 2006, 55(Suppl.), A8.
    • (2006) Gut , vol.55 , Issue.SUPPL.
    • Stephens, P.1    Nesbitt, A.2    Foulkes, R.3
  • 108
    • 69249210924 scopus 로고    scopus 로고
    • A 24-year-old pregnant woman with inflammatory bowel disease
    • Hou, J.K.; Mahadevan, U. A 24-year-old pregnant woman with inflammatory bowel disease. Clin. Gastroenterol. Hepatol., 2009, 7(9), 944-947.
    • (2009) Clin. Gastroenterol. Hepatol. , vol.7 , Issue.9 , pp. 944-947
    • Hou, J.K.1    Mahadevan, U.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.