Topiramate promotes neurological recovery in a new model of traumatic brain injury in rats

Neuroscience

Volumn 183, Issue , 2011, Pages 171-177

  Kouzounias, K ^a   Kimiskidis, V K ^a   Siozos, T ^b   Violaris, K ^b   Kostomitsopoulos, N ^c   Karayannakos, P E ^c   Sotirakoglou, K ^d   Nanassis, K ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b G Papanikolaou Hospital   (Greece)

^c BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^d AGRICULTURAL UNIVERSITY OF ATHENS   (Greece)

Author keywords

Neuroprotection; Topiramate; Traumatic brain injury

Indexed keywords

PLACEBO; TOPIRAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN WATER; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; DRUG MEGADOSE; HEMISPHERE; HISTOPATHOLOGY; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN EDEMA; BRAIN INJURIES; DISEASE MODELS, ANIMAL; FRUCTOSE; FUNCTIONAL LATERALITY; MALE; MULTIVARIATE ANALYSIS; NERVOUS SYSTEM DISEASES; NEUROLOGIC EXAMINATION; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; TIME FACTORS;

EID: 79955582778     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.03.069     Document Type: Article

References (41)

1. Alves O.L., Doyle A.J., Clausen T., Gilman C., Bullock R. Evaluation of topiramate neuroprotective effect in severe TBI using microdialysis. Ann N Y Acad Sci 2003, 993:25-34. discussion 48-53.
2. Angehagen M., Ben-Menachem E., Ronnback L., Hansson E. Topiramate protects against glutamate- and kainate-induced neurotoxicity in primary neuronal-astroglial cultures. Epilepsy Res 2003, 54:63-71.
3. Bullock M.R., Lyeth B.G., Muizelaar J.P. Current status of neuroprotection trials for traumatic brain injury: lessons from animal models and clinical studies. Neurosurgery 1999, 45:207-217. discussion 217-220.
4. Dempsey R.J., Baskaya M.K., Dogan A. Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-d-aspartate receptor antagonist, after experimental traumatic brain injury in rats. Neurosurgery 2000, 47:399-404. discussion 404-406.
5. Edmonds H.L., Jiang Y.D., Zhang P.Y., Shank R. Topiramate as a neuroprotectant in a rat model of global ischemia-induced neurodegeneration. Life Sci 2001, 69:2265-2277.
6. Faden A.I. Neuroprotection and traumatic brain injury: theoretical option or realistic proposition. Curr Opin Neurol 2002, 15:707-712.
7. Faden A.I., Stoica B. Neuroprotection: challenges and opportunities. Arch Neurol 2007, 64:794-800.
8. Frisch C., Kudin A.P., Elger C.E., Kunz W.S., Helmstaedter C. Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent. Epilepsy Res 2007, 73:173-180.
9. Fukui S., Signoretti S., Dunbar J.G., Marmarou A. The effect of cyclosporin A on brain edema formation following experimental cortical contusion. Acta Neurochir Suppl 2003, 86:301-303.
10. Hoover R.C., Motta M., Davis J., Saatman K.E., Fujimoto S.T., Thompson H.J., Stover J.F., Dichter M.A., Twyman R., White H.S., McIntosh T.K. Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain injury in rats. J Neurotrauma 2004, 21:501-512.
11. Kofke W.A. Incrementally applied multifaceted therapeutic bundles in neuroprotection clinical trials...time for change. Neurocrit Care 2010, 12:438-444.
12. Kudin A.P., Debska-Vielhaber G., Vielhaber S., Elger C.E., Kunz W.S. The mechanism of neuroprotection by topiramate in an animal model of epilepsy. Epilepsia 2004, 45:1478-1487.
13. Lee S.R., Kim S.P., Kim J.E. Protective effect of topiramate against hippocampal neuronal damage after global ischemia in the gerbils. Neurosci Lett 2000, 281:183-186.
14. Leker R.R., Neufeld M.Y. Anti-epileptic drugs as possible neuroprotectants in cerebral ischemia. Brain Res Brain Res Rev 2003, 42:187-203.
15. Liu Y., Barks J.D., Xu G., Silverstein F.S. Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats. Stroke 2004, 35:1460-1465.
16. Maas A.I. Neuroprotective agents in traumatic brain injury. Expert Opin Investig Drugs 2001, 10:753-767.
17. McIntosh T.K., Vink R., Noble L., Yamakami I., Fernyak S., Soares H., Faden A.L. Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model. Neuroscience 1989, 28:233-244.
18. Nakamura H., Uzura M., Uchida K., Nakayama H., Furuya Y., Hayashi T., Sekino H., Ominato M., Owada S. Effects of edaravone on experimental brain injury in view of free radical reaction. Acta Neurochir Suppl 2003, 86:309-311.
19. Guide for the care and use of laboratory animals 1996, National Research Council, National Academy Press, Washington, DC. 8th ed.
20. Nicklas W., Baneux P., Boot R., Decelle T., Deeny A.A., Fumanelli M., Illgen-Wilcke B. Recommendations for the health monitoring of rodent and rabbit colonies in breeding and experimental units. Lab Anim 2002, 36:20-42.
21. Noh M.R., Kim S.K., Sun W., Park S.K., Choi H.C., Lim J.H., Kim I.H., Kim H.J., Kim H., Eun B.L. Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats. Exp Neurol 2006, 201:470-478.
22. O'Brien R.G., Kaiser M.K. MANOVA method for analyzing repeated measures designs: an extensive primer. Psychol Bull 1985, 97:316-333.
23. Okiyama K., Smith D.H., White W.F., McIntosh T.K. Effects of the NMDA antagonist CP-98,113 on regional cerebral edema and cardiovascular, cognitive, and neurobehavioral function following experimental brain injury in the rat. Brain Res 1998, 792:291-298.
24. Pitkanen A., Kubova H. Antiepileptic drugs in neuroprotection. Expert Opin Pharmacother 2004, 5:777-798.
25. Rigoulot M.A., Koning E., Ferrandon A., Nehlig A. Neuroprotective properties of topiramate in the lithium-pilocarpine model of epilepsy. J Pharmacol Exp Ther 2004, 308:787-795.
26. Sarrafzadeh A.S., Thomale U.W., Kroppenstedt S.N., Unterberg A.W. Neuroprotective effect of melatonin on cortical impact injury in the rat. Acta Neurochir (Wien) 2000, 142:1293-1299.
27. Schouten J.W. Neuroprotection in traumatic brain injury: a complex struggle against the biology of nature. Curr Opin Crit Care 2007, 13:134-142.
28. Schubert S., Brandl U., Brodhun M., Ulrich C., Spaltmann J., Fiedler N., Bauer R. Neuroprotective effects of topiramate after hypoxia-ischemia in newborn piglets. Brain Res 2005, 1058:129-136.
29. Sfaello I., Baud O., Arzimanoglou A., Gressens P. Topiramate prevents excitotoxic damage in the newborn rodent brain. Neurobiol Dis 2005, 20:837-848.
30. Shank R.P., Gardocki J.F., Streeter A.J., Maryanoff B.E. An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanism of action. Epilepsia 2000, 41(Suppl 1):S3-S9.
31. Shapira Y., Shohami E., Sidi A., Soffer D., Freeman S., Cotev S. Experimental closed head injury in rats: mechanical, pathophysiologic, and neurologic properties. Crit Care Med 1988, 16:258-265.
32. Shohami E., Novikov M., Bass R. Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat. Brain Res 1995, 674:55-62.
33. Smith-Swintosky V.L., Zhao B., Shank R.P., Plata-Salaman C.R. Topiramate promotes neurite outgrowth and recovery of function after nerve injury. Neuroreport 2001, 12:1031-1034.
34. Soares H.D., Thomas M., Cloherty K., McIntosh T.K. Development of prolonged focal cerebral edema and regional cation changes following experimental brain injury in the rat. J Neurochem 1992, 58:1845-1852.
35. Tagliaferri F., Compagnone C., Korsic M., Servadei F., Kraus J. A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien) 2006, 148:255-268. discussion 268.
36. Tolias C.M., Bullock M.R. Critical appraisal of neuroprotection trials in head injury: what have we learned?. NeuroRx 2004, 1:71-79.
37. Trojnar M.K., Malek R., Chroscinska M., Nowak S., Blaszczyk B., Czuczwar S.J. Neuroprotective effects of antiepileptic drugs. Pol J Pharmacol 2002, 54:557-566.
38. Wang P., Ren R.N., Cai S.Y., Chen X.M., Ye L.Y. [Neuroprotective effects of topiramate and folic acid on young rats with kindling-induced epilepsy]. Zhongguo Dang Dai Er Ke Za Zhi 2008, 10:65-69.
39. Xiong Y., Mahmood A., Chopp M. Emerging treatments for traumatic brain injury. Expert Opin Emerg Drugs 2009, 14:67-84.
40. Yang Y., Li Q., Shuaib A. Enhanced neuroprotection and reduced hemorrhagic incidence in focal cerebral ischemia of rat by low dose combination therapy of urokinase and topiramate. Neuropharmacology 2000, 39:881-888.
41. Yang Y., Shuaib A., Li Q., Siddiqui M.M. Neuroprotection by delayed administration of topiramate in a rat model of middle cerebral artery embolization. Brain Res 1998, 804:169-176.