A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a

Journal of Biological Chemistry

Volumn 285, Issue 21, 2010, Pages 16315-16329

  Liechti, Luz Angé Lica ^a   Bernèche, Simon ^b,c   Bargeton, Benoîte ^a   Iwaszkiewicz, Justyna ^b   Roy, Sophie ^a   Michielin, Olivier ^b   Kellenberger, Stephan ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-SENSING ION CHANNELS; CONFORMATIONAL CHANGE; EXTRACELLULAR; FUNCTIONAL APPROACH; NEURODEGENERATION; PAIN SENSATION; PH CHANGE; PH DEPENDENCE; PH VARIATION; PH-DEPENDENT; SITE DIRECTED MUTAGENESIS; VERTICAL AXIS;

CHEMICAL MODIFICATION; ENZYME ACTIVITY;

ELECTRIC POWER SUPPLIES TO APPARATUS;

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; ASPARTIC ACID; GLUTAMIC ACID; HISTIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CHANNEL GATING; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; NONHUMAN; OOCYTE; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTON TRANSPORT; SENSOR; SITE DIRECTED MUTAGENESIS; XENOPUS LAEVIS;

AMINO ACID SUBSTITUTION; HUMANS; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, TERTIARY; SODIUM CHANNELS;

EID: 77952365948     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.092015     Document Type: Article

References (46)

1. Krishtal, O. (2003) Trends Neurosci. 26, 477-483
2. Wemmie, J. A., Price, M. P., and Welsh, M. J. (2006) Trends Neurosci. 29, 578-586
3. Kellenberger, S., and Schild, L. (2002) Physiol. Rev. 82, 735-767
4. Sutherland, S. P., Benson, C. J., Adelman, J. P., and McCleskey, E. W. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 711-716
5. Sluka, K. A., Price, M. P., Breese, N. M., Stucky, C. L., Wemmie, J. A., and Welsh, M. J. (2003) Pain 106, 229-239
6. Deval, E., Noël, J., Lay, N., Alloui, A., Diochot, S., Friend, V., Jodar, M., Lazdunski, M., and Lingueglia, E. (2008) EMBO J. 27, 3047-3055
7. Mogil, J. S., Breese, N. M., Witty, M. F., Ritchie, J., Rainville, M. L., Ase, A., Abbadi, N., Stucky, C. L., and Séguéla, P. (2005) J. Neurosci. 25, 9893-9901
8. Wemmie, J. A., Chen, J., Askwith, C. C., Hruska-Hageman, A. M., Price, M. P., Nolan, B. C., Yoder, P. G., Lamani, E., Hoshi, T., Freeman, J. H., Jr., and Welsh, M. J. (2002) Neuron 34, 463-477
9. Wemmie, J. A., Askwith, C. C., Lamani, E., Cassell, M. D., Freeman, J. H., Jr., and Welsh, M. J. (2003) J. Neurosci. 23, 5496-5502
10. Xiong, Z. G., Zhu, X. M., Chu, X. P., Minami, M., Hey, J., Wei, W. L., MacDonald, J. F., Wemmie, J. A., Price, M. P., Welsh, M. J., and Simon, R. P. (2004) Cell 118, 687-698
11. Hesselager, M., Timmermann, D. B., and Ahring, P. K. (2004) J. Biol. Chem. 279, 11006-11015
12. Yagi, J., Wenk, H. N., Naves, L. A., and McCleskey, E. W. (2006) Circ. Res. 99, 501-509
13. Lingueglia, E., de Weille, J. R., Bassilana, F., Heurteaux, C., Sakai, H., Waldmann, R., and Lazdunski, M. (1997) J. Biol. Chem. 272, 29778-29783
14. Waldmann, R., Bassilana, F., de Weille, J., Champigny, G., Heurteaux, C., and Lazdunski, M. (1997) J. Biol. Chem. 272, 20975-20978
15. Babini, E., Paukert, M., Geisler, H. S., and Grunder, S. (2002) J. Biol. Chem. 277, 41597-41603
16. Benson, C. J., Xie, J., Wemmie, J. A., Price, M. P., Henss, J. M., Welsh, M. J., and Snyder, P. M. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 2338-2343
17. Poirot, O., Vukicevic, M., Boesch, A., and Kellenberger, S. (2004) J. Biol. Chem. 279, 38448-38457
18. Immke, D. C., and McCleskey, E. W. (2003) Neuron 37, 75-84
19. Zhang, P., Sigworth, F. J., and Canessa, C. M. (2006) J. Gen. Physiol. 127, 109-117
20. Paukert, M., Babini, E., Pusch, M., and Gründer, S. (2004) J. Gen Physiol. 124, 383-394
21. Adams, C. M., Snyder, P. M., Price, M. P., and Welsh, M. J. (1998) J. Biol. Chem. 273, 30204-30207
22. Coric, T., Zheng, D., Gerstein, M., and Canessa, C. M. (2005) J. Physiol. 568, 725-735
23. Paukert, M., Chen, X., Polleichtner, G., Schindelin, H., and Gründer, S. (2008) J. Biol. Chem. 283, 572-581
24. Smith, E. S., Zhang, X., Cadiou, H., and McNaughton, P. A. (2007) Neurosci. Lett. 426, 12-17
25. Jasti, J., Furukawa, H., Gonzales, E. B., and Gouaux, E. (2007) Nature 449, 316-323
26. Gonzales, E. B., Kawate, T., and Gouaux, E. (2009) Nature 460, 599-604
27. Martí-Renom, M. A., Stuart, A. C., Fiser, A., Sánchez, R., Melo, F., and Sali, A. (2000) Annu. Rev. Biophys. Biomol. Struct. 29, 291-325
28. Shen, M. Y., and Sali, A. (2006) Protein Sci. 15, 2507-2524
29. Melo, F., and Feytmans, E. (1997) J. Mol. Biol. 267, 207-222
30. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
31. Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., and Ferrin, T. E. (2004) J. Comput. Chem. 25, 1605-1612
32. Bashford, D., and Karplus, M. (1990) Biochemistry 29, 10219-10225
33. Im, W., Beglov, D., and Roux, B. (1998) Comp. Phys. Commun. 111, 59-75
34. Brooks, B. R., Bruccoleri, R. E., Olafson, B. D., States, D. J., Swminathan, S., and Karplus, M. (1983) J. Comp. Chem. 4, 187-217
35. Roux, B., Bernèche, S., and Im, W. (2000) Biochemistry 39, 13295-13306
36. Vukicevic, M., Weder, G., Boillat, A., Boesch, A., and Kellenberger, S. (2006) J. Biol. Chem. 281, 714-722
37. Sánchez, R., and Sali, A. (2000) Methods Mol. Biol. 143, 97-129
38. Hidalgo, P., and MacKinnon, R. (1995) Science 268, 307-310
39. Eisenberg, D., and McLachlan, A. D. (1986) Nature 319, 199-203
40. Cushman, K. A., Marsh-Haffner, J., Adelman, J. P., and McCleskey, E. W. (2007) J. Gen. Physiol. 129, 345-350
41. Sherwood, T., Franke, R., Conneely, S., Joyner, J., Arumugan, P., and Askwith, C. (2009) J. Biol. Chem. 284, 27899-27907
42. Yang, H., Yu, Y., Li, W. G., Yu, F., Cao, H., Xu, T. L., and Jiang, H. (2009) PLoS Biol. 7, e1000151
43. Li, T., Yang, Y., and Canessa, C. M. (2009) J. Biol. Chem. 284, 4689-4694
44. Baron, A., Schaefer, L., Lingueglia, E., Champigny, G., and Lazdunski, M. (2001) J. Biol. Chem. 276, 35361-35367
45. Bässler, E. L., Ngo-Anh, T. J., Geisler, H. S., Ruppersberg, J. P., and Gründer, S. (2001) J. Biol. Chem. 276, 33782-33787
46. Bargeton, B., and Kellenberger, S. (2010) J. Biol. Chem. 285, 13816-13826