Over-Expression of YLR162W in Saccharomyces cerevisiae Inhibits Cell Proliferation and Renders Cells Susceptible to the Hypoxic Conditions Induced by Cobalt Chloride

Indian Journal of Microbiology

Volumn 51, Issue 2, 2011, Pages 206-211

  Kumar, Navin ^a,b   Meena, Ramesh C ^a   Chakrabarti, Amitabha ^a  

^a DEFENCE INSTITUTE OF PHYSIOLOGY AND ALLIED SCIENCES   (India)

^b Panacea Biotech Ltd   (India)

Author keywords

Apoptosis; Hypoxia; Mitochondrial membrane potential; Saccharomyces cerevisiae; YLR162W

Indexed keywords

SACCHAROMYCES CEREVISIAE;

EID: 79955545802     PISSN: 00468991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12088-011-0132-3     Document Type: Article

References (20)

1. Klein P, Kanehisa M, DeLisi C (1985) The detection and classification of membrane-spanning proteins. Biochim Biophys Acta 815: 468-476.
2. Von Heijne G, Gavel Y (1988) Topogenic signals in integral membrane proteins. Eur J Biochem 174: 671-678.
3. Stephens C, Harrison SJ, Kazan K, Smith FWN, Goulter KC, Maclean DJ, Manners JM (2005) Altered fungal sensitivity to a plant antimicrobial peptide through over-expression of yeast cDNAs. Curr Genet 47: 194-201.
4. Shcherbakova PV, Hall MC, Lewis MC, Bennett SE, Martin KJ, Bushel PR, Afshari CA, Kunkel TA (2001) Inactivation of DNA mismatch repair by increased expression of yeast MLH1. Mol Cell Biol 21: 940-951.
5. Matsuoka H, Suzuki Y, Iwahashi H, Arao T, Suzuki Y, Tamura K (2005) The biological effects of high-pressure on the yeast transcriptome. Braz J Med Biol Res 38: 1267-1272.
6. 2+/calceneurin signaling in Saccharomyces cerevisiae. Eukaryot Cell 6: 592-599.
7. Roberts CJ, Nelson B, Marton MJ, Stoughton R, Meyer MR, Bennett HA, He YD, Dai H, Walker WL, Hughes TR, Tyers M, Boone C, Friend SH (2000) Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. Science 287: 873-880.
8. Gasch AP, Spellman PT, Kao CM, Carmel-Harel O, Eisen MB, Storz G, Botstein D, Brown PO (2000) Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell 11: 4241-4257.
9. Lai LC, Kosorukoff AL, Burke PV, Kwast KE (2006) Metabolic-state-dependent remodeling of the transcriptome in response to anoxia and subsequent reoxygenation in Saccharomyces cerevisiae. Eukaryotic Cell 5: 1468-1489.
10. Kwast KE, Lai L-C, Menda N, James DT III, Aref S, Burke PV (2002) Genomic analyses of anaerobically induced genes in Saccharomyces cerevisiae: functional roles of Rox1 and other factors in mediating the anoxic response. J Bacteriol 184: 250-265.
11. Wang GL, Semenza GL (1995) Purification and characterization of hypoxia inducible factor 1. J Biol Chem 270: 1230-1237.
12. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. CSHL Press, NewYork.
13. Diatchenko L, Lau Y-FC, Campbell AP, Chenchik A, Moqadm F, Huang B, Lukyanov S, Lukyanov K, Gurskaya N, Sverdlot E, Siebert PD (1996) Suppression subtractive hybridization: A method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc Natl Acad Sci USA 93: 6025-6030.
14. Lee S-J, Schwartz MF, Duong JK, Stern DF (2003) Rad53 phosphorylation sites clusters are important for Rad53 regulation and signaling. Mol Cell Biol 23: 6300-6314.
15. MacKAY VJ, Mal B, Waters L, Breeden LL (2001) Early cell cycle box-mediated transcription of CLN3 and SWI4 contributes to the proper timing of the G1-to-S transition in budding yeast. Mol Cell Biol 21: 4140-4148.
16. Ludovico P, Sousa MJ, Silva MT, Leao C, Côrte-Real M (2001) Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid. Microbiology 147: 2409-2415.
17. Kajstura M, Halicka DH, Pryjma J, Darzynkiewicz Z (2007) Discontinuous fragmentation of nuclear DNA during apoptosis revealed by discrete "Sub-G1" peaks on DNA content histograms. Cytometry Part A 71A: 125-131.
18. Nargund AM, Avery SV, Houghton JF (2008) Cadmium induces a heterogeneous and caspase-dependent apoptotic response in Saccharomyces cerevisiae. Apoptosis 13: 811-821.
19. Elledge SJ (1996) Cell cycle checkpoints: Preventing an identity crisis. Science 274: 1664-1672.
20. Burhans WC, Weinberger M, Marchetti MA, Ramachandran L, D'Urso G, Huberman JA (2003) Apoptosis-like yeast cell death in response to DNA damage and replication defects. Mutat Res 532: 227-243.