Microscopic mammalian retinal pigment epithelium lesions induce widespread proliferation with differences in magnitude between center and periphery

Molecular Vision

Volumn 16, Issue , 2010, Pages 570-581

  von Leithner, Peter Lundh ^a   Ciurtin, Coziana ^b   Jeffery, Glen ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; GELATINASE A; KI 67 ANTIGEN;

ALBINISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; HYPOPIGMENTATION; LASER; MITOSIS; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RAT; RETINA INJURY; RETINA NEUROEPITHELIAL LAYER; ANIMAL; CELL CYCLE; FLUORESCENCE; LASER COAGULATION; MAMMAL; METABOLISM; PATHOLOGY; WOUND HEALING;

ANIMALS; BROMODEOXYURIDINE; CELL COUNT; CELL CYCLE; CELL PROLIFERATION; FLUORESCENCE; KI-67 ANTIGEN; LIGHT COAGULATION; MAMMALS; RATS; RETINAL PIGMENT EPITHELIUM; WOUND HEALING;

EID: 77952302731     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Fernald RD. Teleost vision: seeing while growing. J Exp Zool Suppl 1990; 5:167-180. [PMID: 1982493]
2. Tropepe V, Hitoshi S, Sirard C, Mak TW, Rossant J, van der Kooy D. Direct Neural Fate Specification from Embryonic Stem Cells A Primitive Mammalian Neural Stem Cell Stage Acquired through a Default Mechanism. Neuron 2001; 30:65-78. [PMID: 11343645]
3. Al-Hussaini H, Kam JH, Vugler A, Semo M, Jeffery G. Matureretinal pigment epithelium cells are retained in the cell cycle and proliferate in vivo. Mol Vis 2008; 14:1784-1791. [PMID: 18843376]
4. Del Priore LV, Kuo YH, Tezel TH. Age-related changes in human RPE cell density and apoptosis proportion in situ.Invest Ophthalmol Vis Sci 2002; 43:3312-3318. [PMID: 12356840]
5. Pollack A, Heriot WJ. Cellular processes causing defects in Bruch's membrane following krypton laser photocoagulation. Ophthalmology 1986; 93:1113-1119. [PMID: 3763161]
6. Pollack A, Korte GE. Repair of retinal pigment epithelium and its relationship with capillary endothelium after krypton laser photocoagulation. Invest Ophthalmol Vis Sci 1990; 31:890. [PMID: 2335451]
7. Wallow IH, Tso MO. Repair after xenon arc photocoagulation. 3. An electron microscopic study of the evolution of retinal lesions in rhesus monkeys. Am J Ophthalmol 1973; 75:957. [PMID: 4196669]
8. Jo N, Ju M, Nishijima K, Robinson GS, Adamis AP, Shima DT, Mailhos C. Inhibitory effect of an antibody to cryptic collagen type IV epitopes on choroidal neovascularization. Mol Vis 2006; 12:1243-1249. [PMID: 17110907]
9. Williams CD, Rizzolo LJ. Remodeling of junctional complexes during the development of the outer blood-retinal barrier. Anat Rec 1997; 249:380-388. [PMID: 9372172]
10. Adams T, Shahabi G, Hoh-Kam J, Jeffery G. Held under arrest: Many mature albino RPE cells display polyploidal features consistent with abnormal cell cycle retention. Exp Eye Res 2010; 90:368-372. [PMID: 19833124]
11. Tang X, Zhang X, Xu H. Establishment of hybidoma cell lines producing monoclonal antibodies against hepatitis B virus surface antigens (a, d and r) and development of sensitive ELISA diagnostic test. Hybridoma 2001; 20:47-52. [PMID: 11289227]
12. Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol 2000; 182:311-322. [PMID: 10653597]
13. Pollack A, Korte GE, Heriot WJ, Henkind P. Ultrastructure of Bruch's membrane after krypton laser photocoagulation: II. Repair of Bruch's membrane and the role of macrophages. Arch Ophthalmol 1986; 104:1377. [PMID: 2428346]
14. Dobi ET, Puliafito CA, Destro M. A new model of experimental choroidal neovascularization in the rat. Arch Ophthalmol 1989; 107:264. [PMID: 2464985]
15. Cernak I, Stoica B, Byrnes KR, Di Giovanni S, Faden AI. Role of the cell cycle in the pathobiology of central nervous system trauma. Cell Cycle 2005; 4:1286-1293. [PMID: 16082214]
16. Yang Y, Herrup K. Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta 2007; 1772:457-466. [PMID: 17158035]
17. Ishibashi K, Tian J, Handa JT. Similarity of mRNA phenotypes of morphologically normal macular and peripheral retinal pigment epithelial cells in older human eyes. Invest Ophthalmol Vis Sci 2004; 45:3291. [PMID: 15326154]
18. Hollyfield JG. Histogenesis of the retina in the killifish, Fundulus heteroclitus. J Comp Neurol 1972; 144:373-379. [PMID: 5027336]
19. Kahn AJ. An autoradiographic analysis of the time of appearance of neurons in the developing chick neural retina. Dev Biol 1974; 38:30. [PMID: 4856982]
20. la Vail MM, Rapaport DH, Rakic P. Cytogenesis in the monkey retina. J Comp Neurol 1991; 309:86-114. [PMID: 1894769]
21. Straznicky K, Gaze RM. The growth of the retina in Xenopus laevis: an autoradiographic study. J Embryol Exp Morphol 1971; 26:67-79. [PMID: 5565078]
22. Tibber MS, Becker D, Jeffery G. Levels of transient gap junctions between the retinal pigment epithelium and the neuroblastic retina are influenced by catecholamines and correlate with patterns of cell production. J Comp Neurol 2007; 503:128. [PMID: 17480016]
23. Tibber MS, Whitmore AV, Jeffery G. Cell division and cleavage orientation in the developing retina are regulated by L-DOPA. J Comp Neurol 2006; 496:369. [PMID: 16566005]
24. Ogata N, Ando A, Uyama M, Matsumura M. Expression of cytokines and transcription factors in photocoagulated human retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol 2001; 239:87-95. [PMID: 11372550]
25. Ogata N, Yamamoto C, Miyashiro M, Yamada H, Matsushima M, Uyama M. Expression of transforming growth factor-fl mRNA in experimental choroidal neovascularization. Curr Eye Res 1997; 16:9-18. [PMID: 9043818]
26. Joo CK, Seomun Y. Matrix metalloproteinase (MMP) and TGF 1-stimulated cell migration in skin and cornea wound healing. Cell Adh Migr. 2008; 2:252-253. [PMID: 19262153]
27. Kim DS, Park SH, Park KC. Transforming growth factor-beta1 decreases melanin synthesis via delayed extracellular signalregulated kinase activation. Int J Biochem Cell Biol 2004; 36:1482-1491. [PMID: 15147727]
28. Wall GL. The vertebrate eye and its adaptive radiation. Bloomfield Hills, MI: Cranbrook Inst of Sci.; 1942.