Cardiac-specific overexpression of E3 ligase Nrdp1 increases ischemia and reperfusion-induced cardiac injury

Basic Research in Cardiology

Volumn 106, Issue 3, 2011, Pages 371-383

  Zhang, Yuan ^a   Zeng, Yong ^b   Wang, Min ^a   Tian, Cui ^c   Ma, Xu ^d   Chen, Houzao ^a   Fang, Quan ^b   Jia, Lixin ^e   Du, Jie ^e   Li, Huihua ^c  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^e CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Inflammation; Ischemia reperfusion; Myocardium; Nrdp1

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 3; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUREGULIN RECEPTOR DEGRADATION PROTEIN 1; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE 1; SYNAPTOPHYSIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE; GENE EXPRESSION; HEART INFARCTION SIZE; HEART INJURY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; INFLAMMATION; INFLAMMATORY CELL; MOUSE; NEWBORN; NONHUMAN; NRDP1 GENE; PROTEIN EXPRESSION; REPERFUSION INJURY; WILD TYPE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARRIER PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATION; ISCHEMIA; MICE; MICE, TRANSGENIC; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 79955541868     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-011-0157-0     Document Type: Article

References (36)

1. Armstrong SC (2004) Protein kinase activation and myocardial ischemia/reperfusion injury. Cardiovasc Res 61:427-436. doi: 10.1016/j.cardiores.2003.09.031S000863630300662x (Pubitemid 38210149)
2. CP Baines JD Molkentin 2005 STRESS signaling pathways that modulate cardiac myocyte apoptosis J Mol Cell Cardiol 38 47 62 15623421 10.1016/j.yjmcc.2004.11.004 1:CAS:528:DC%2BD2cXhtFGgs7vE (S0022-2828(04)00325-6) (Pubitemid 40038651)
3. K Boengler D Hilfiker-Kleiner H Drexler G Heusch R Schulz 2008 The myocardial JAK/STAT pathway: from protection to failure Pharmacol Ther 120 172 185 18786563 10.1016/j.pharmthera.2008.08.002 1:CAS:528:DC%2BD1cXht1Knsb3J (S0163-7258(08)00140-x)
4. RA Bowden ZM Ding EM Donnachie TK Petersen LH Michael CM Ballantyne AR Burns 2002 Role of alpha4 integrin and VCAM-1 in CD18-independent neutrophil migration across mouse cardiac endothelium Circ Res 90 562 569 10.1161/01.RES.0000013835.53611.97 11909820 10.1161/01.RES.0000013835.53611.97 1:CAS:528:DC%2BD38XisFSktL4%3D (Pubitemid 34640906)
5. TD Camenisch JA Schroeder J Bradley SE Klewer JA McDonald 2002 Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors Nat Med 8 850 855 10.1038/nm742nm742 12134143 1:CAS:528:DC%2BD38Xls12mt7w%3D
6. Z Cao X Wu L Yen C Sweeney KL Carraway 3rd 2007 Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1 Mol Cell Biol 27 2180 2188 17210635 10.1128/MCB.01245-06 1:CAS:528:DC%2BD2sXjsVSrsb4%3D (MCB.01245-06) (Pubitemid 46418474)
7. AJ Diamonti PM Guy C Ivanof K Wong C Sweeney KL Carraway 3rd 2002 An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels Proc Natl Acad Sci USA 99 2866 2871 10.1073/pnas.052709799 11867753 10.1073/pnas.052709799 1:CAS:528:DC%2BD38Xit1CrtLc%3D (Pubitemid 34240552)
8. F Eefting B Rensing J Wigman WJ Pannekoek WM Liu MJ Cramer DJ Lips PA Doevendans 2004 Role of apoptosis in reperfusion injury Cardiovasc Res 61 414 426 10.1016/j.cardiores.2003.12.023S0008636303007910 14962473 10.1016/j.cardiores.2003.12.023 1:CAS:528:DC%2BD2cXhtFWms7Y%3D (Pubitemid 38210148)
9. Y Feng H Zhao X Xu ES Buys MJ Raher JC Bopassa H Thibault M Scherrer-Crosbie U Schmidt W Chao 2008 Innate immune adaptor MyD88 mediates neutrophil recruitment and myocardial injury after ischemia-reperfusion in mice Am J Physiol Heart Circ Physiol 295 H1311 H1318 18660455 10.1152/ajpheart.00119. 2008 1:CAS:528:DC%2BD1cXhtFCgtL%2FF (00119.2008)
10. SJ Fuller K Sivarajah PH Sugden 2008 ErbB receptors, their ligands, and the consequences of their activation and inhibition in the myocardium J Mol Cell Cardiol 44 831 854 18430438 10.1016/j.yjmcc.2008.02.278 1:CAS:528: DC%2BD1cXlvVSitLs%3D (S0022-2828(08)00343-x)
11. T Ha F Hua Y Li J Ma X Gao J Kelley A Zhao GE Haddad DL Williams IW Browder RL Kao C Li 2006 Blockade of MyD88 attenuates cardiac hypertrophy and decreases cardiac myocyte apoptosis in pressure overload-induced cardiac hypertrophy in vivo Am J Physiol 290 H985 994 1:CAS:528:DC%2BD28XjtFCgtr4%3D (00720.2005)
12. HP Hauser M Bardroff G Pyrowolakis S Jentsch 1998 A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors J Cell Biol 141 1415 1422 10.1083/jcb.141.6.1415 9628897 10.1083/jcb.141.6.1415 1:CAS:528:DyaK1cXjvFKktr4%3D (Pubitemid 28289916)
13. G Heusch 2009 No risk, no cardioprotection? A critical perspective Cardiovasc Res 84 173 175 19713282 10.1093/cvr/cvp298 1:CAS:528: DC%2BD1MXht1OrtLvK (cvp298)
14. G Heusch K Boengler R Schulz 2008 Cardioprotection: nitric oxide, protein kinases, and mitochondria Circulation 118 1915 1919 118/19/1915 18981312 10.1161/CIRCULATIONAHA.108.805242
15. Hosoda T, Kajstura J, Leri A, Anversa P (2010) Mechanisms of myocardial regeneration. Circ J 74:13-17. doi: JST.JSTAGE/circj/CJ-09-0665
16. F Li P Xie Y Fan H Zhang L Zheng D Gu C Patterson H Li 2009 C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1 J Biol Chem 284 20090 20098 M109.017046 19483080 10.1074/jbc.M109.017046 1:CAS:528: DC%2BD1MXos1ens74%3D
17. HH Li V Kedar C Zhang H McDonough R Arya DZ Wang C Patterson 2004 Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex J Clin Invest 114 1058 1071 10.1172/JCI22220 15489953 1:CAS:528:DC%2BD2cXovVensr0%3D (Pubitemid 39578695)
18. HH Li MS Willis P Lockyer N Miller H McDonough DJ Glass C Patterson 2007 Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins J Clin Invest 117 3211 3223 10.1172/JCI31757 17965779 10.1172/JCI31757 1:CAS:528:DC%2BD2sXht12isrzF (Pubitemid 350096979)
19. T Li Y Wang C Liu Y Hu M Wu J Li L Guo L Chen Q Chen T Ha C Li Y Li 2009 MyD88-dependent nuclear factor-kappaB activation is involved in fibrinogen-induced hypertrophic response of cardiomyocytes J Hypertens 27 1084 1093 10.1097/HJH.0b013e3283293c93 19342961 10.1097/HJH.0b013e3283293c93 1:CAS:528:DC%2BD1MXltVags7o%3D
20. YH Liao X Cheng 2006 Autoimmunity in myocardial infarction Int J Cardiol 112 21 26 16837084 10.1016/j.ijcard.2006.05.009 (S0167-5273(06)00560-2) (Pubitemid 44262406)
21. SE Logue AB Gustafsson A Samali RA Gottlieb 2005 Ischemia/reperfusion injury at the intersection with cell death J Mol Cell Cardiol 38 21 33 15623419 10.1016/j.yjmcc.2004.11.009 1:CAS:528:DC%2BD2cXhtFGgs7vP (S0022-2828(04)00330-x) (Pubitemid 40044759)
22. F Lopez-Neblina AH Toledo LH Toledo-Pereyra 2005 Molecular biology of apoptosis in ischemia and reperfusion J Invest Surg 18 335 350 16319055 10.1080/08941930500328862 (K3574075H438W921) (Pubitemid 43123614)
23. A Negro BK Brar KF Lee 2004 Essential roles of Her2/erbB2 in cardiac development and function Recent Prog Horm Res 59 1 12 10.1210/rp.59.1.1 14749494 10.1210/rp.59.1.1 1:CAS:528:DC%2BD2cXisFKhtrc%3D (Pubitemid 41327144)
24. LH Opie PJ Commerford BJ Gersh MA Pfeffer 2006 Controversies in ventricular remodelling Lancet 367 356 367 16443044 10.1016/S0140-6736(06)68074- 4 (S0140-6736(06)68074-4) (Pubitemid 43151469)
25. RZ Orlowski 1999 The role of the ubiquitin-proteasome pathway in apoptosis Cell Death Differ 6 303 313 10.1038/sj.cdd.4400505 10381632 10.1038/sj.cdd.4400505 1:CAS:528:DyaK1MXivFSqsr8%3D (Pubitemid 29186874)
26. XB Qiu AL Goldberg 2002 Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3 Proc Natl Acad Sci USA 99 14843 14848 10.1073/pnas.232580999 12411582 10.1073/pnas.232580999 1:CAS:528:DC%2BD38Xpt1yrt78%3D (Pubitemid 35334571)
27. XB Qiu SL Markant J Yuan AL Goldberg 2004 Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis EMBO J 23 800 810 10.1038/sj.emboj.7600075 14765125 10.1038/sj.emboj.7600075 1:CAS:528:DC%2BD2cXhsFCjt70%3D (Pubitemid 38418747)
28. D Riethmacher E Sonnenberg-Riethmacher V Brinkmann T Yamaai GR Lewin C Birchmeier 1997 Severe neuropathies in mice with targeted mutations in the ErbB3 receptor Nature 389 725 730 10.1038/39593 9338783 10.1038/39593 1:CAS:528:DyaK2sXmvVSgsbs%3D (Pubitemid 27458958)
29. A Skyschally P van Caster K Boengler P Gres J Musiolik D Schilawa R Schulz G Heusch 2009 Ischemic postconditioning in pigs: no causal role for RISK activation Circ Res 104 15 18 19038864 10.1161/CIRCRESAHA.108.186429 1:CAS:528:DC%2BD1cXhsFSmt7%2FJ (CIRCRESAHA.108.186429)
30. A Toth P Nickson LL Qin P Erhardt 2006 Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase J Biol Chem 281 3679 3689 16339144 10.1074/jbc.M509630200 1:CAS:528: DC%2BD28XhtFSmt7k%3D (M509630200) (Pubitemid 43845986)
31. C Wang T Chen J Zhang M Yang N Li X Xu X Cao 2009 The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon Nat Immunol 10 744 752 19483718 10.1038/ni.1742 1:CAS:528:DC%2BD1MXms1alt7s%3D (ni.1742)
32. X Wu L Yen L Irwin C Sweeney KL Carraway 3rd 2004 Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8 Mol Cell Biol 24 7748 7757 10.1128/MCB.24.17.7748-7757.200424/17/7748 15314180 10.1128/MCB.24.17.7748-7757.2004 1:CAS:528:DC%2BD2cXntVKhu7g%3D (Pubitemid 39121498)
33. P Xie S Guo Y Fan H Zhang D Gu H Li 2009 Atrogin-1/MAFbx enhances simulated ischemia/reperfusion-induced apoptosis in cardiomyocytes through degradation of MAPK phosphatase-1 and sustained JNK activation J Biol Chem 284 5488 5496 19117950 10.1074/jbc.M806487200 1:CAS:528:DC%2BD1MXitFSntbs%3D (M806487200)
34. L Yen Z Cao X Wu ER Ingalla C Baron LJ Young JP Gregg RD Cardiff AD Borowsky C Sweeney KL Carraway 3rd 2006 Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth Cancer Res 66 11279 11286 17145873 10.1158/0008-5472.CAN-06-2319 1:CAS:528:DC%2BD28Xht1KnsL%2FF (66/23/11279) (Pubitemid 46009957)
35. SF Yet R Tian MD Layne ZY Wang K Maemura M Solovyeva B Ith LG Melo L Zhang JS Ingwall VJ Dzau ME Lee MA Perrella 2001 Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice Circ Res 89 168 173 10.1161/hh1401.093314 11463724 10.1161/hh1401.093314 1:CAS:528:DC%2BD3MXlsFahtLw%3D (Pubitemid 34135825)
36. C Zhang Z Xu XR He LH Michael C Patterson 2005 CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice Am J Physiol Heart Circ Physiol 288 H2836 H2842 15665051 10.1152/ajpheart.01122.2004 1:CAS:528:DC%2BD2MXlsVyntL0%3D (01122.2004) (Pubitemid 40720665)