Formation of N-methylnicotinamide in the brain from a dihydropyridine-type prodrug. Effect on brain choline

Biochemical Pharmacology

Volumn 57, Issue 6, 1999, Pages 681-684

  Erb, Christina ^a   Seidel, Albrecht ^a   Frank, Heinz ^a   Platt, Karl L ^a   Oesch, Franz ^a   Klein, Jochen ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Brain targeting; Choline; Hippocampus; Microdialysis; N methylnicotinamide; Nicotinamide

Indexed keywords

1,4 DIHYDRO N METHYLNICOTINAMIDE; CHOLINE; DIHYDROPYRIDINE DERIVATIVE; N METHYLNICOTINAMIDE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG SYNTHESIS; EXTRACELLULAR FLUID; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER LEVEL; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; BRAIN; CHOLINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIHYDROPYRIDINES; LIVER; MALE; MICRODIALYSIS; NIACINAMIDE; PRODRUGS; RATS; RATS, WISTAR;

EID: 0033559394     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00338-4     Document Type: Article

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