Autism spectrum disorders in adulthood: Clinical and neuropsychological findings of aspergers syndrome diagnosed late in life;Autismus-Spektrum-Störungen im Erwachsenenalter: klinische und neuropsychologische Befunde spätdiagnostizierter Asperger-Syndrome

Fortschritte der Neurologie Psychiatrie

Volumn 79, Issue 5, 2011, Pages 290-297

  Lehnhardt, F G ^a   Gawronski, A ^a   Volpert, K ^a   Schilbach, L ^a   Tepest, R ^a   Huff, W ^a   Vogeley, K ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

Asperger syndrome; autism spectrum quotient; diagnosis late in life; high functioning autism; neuropsychological profile; theory of mind

Indexed keywords

ADULT; ADULTHOOD; ARTICLE; ASPERGER SYNDROME; AUTISM; AUTISM SPECTRUM QUOTIENT; BECK DEPRESSION INVENTORY; CLINICAL ARTICLE; CONTROLLED STUDY; COWAT; HAWIE R; HIGH FUNCTIONING AUTISM; HUMAN; INTELLIGENCE QUOTIENT; NEUROPSYCHOLOGICAL TEST; THEORY OF MIND;

EID: 79955518084     PISSN: 07204299     EISSN: 14393522     Source Type: Journal    
DOI: 10.1055/s-0031-1273233     Document Type: Article

References (66)

1. Wing L, Potter D. The epidemiology of autistic spectrum disorders: is the prevalence rising? Ment Retard Dev Disabil Res Rev 2002 8 151-161 (Pubitemid 36378157)
2. Vogeley K, Lehnhardt F G. Hochfunktionaler Autismus im Erwachsenenalter. Nervenheilkunde 2008 27 61-69
3. Tantam D. Psychological disorder in adolescents and adults with Asperger-Syndrom. Autism 2000 4 47-62 (Pubitemid 30168846)
4. Vogeley K, Remschmidt H. Hochfunktionaler Autismus im Erwachsenenalter. In: Vorderholzer U Hohagen F (Hrsg.) Therapie psychischer Erkrankungen. 5. Aufl. Elsevier 2009
5. Schonauer K, Klar M, Kehrer H E. et al. [The course of infantile autism through adulthood. An overview of long-term follow-up data]. Fortschr Neurol Psychiatr 2001 69 221-235
6. Roy M, Dillo W, Emrich H M. et al. Aspergers syndrome in adulthood. Dtsch Arztebl Int 2009 106 59-64
7. Hofvander B, Delorme R, Chaste P et al. Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders. BMC Psychiatry 2009 9 35
8. Ketelaars C, Horwitz E, Sytema S et al. Brief report: adults with mild autism spectrum disorders (ASD): scores on the autism spectrum quotient (AQ) and comorbid psychopathology. J Autism Dev Disord 2008 38 176-180
9. Sizoo B B., Brink B W., Gorissen-Eenige M van den et al. Using the Autism-Spectrum Quotient to Discriminate Autism Spectrum Disorder from ADHD in Adult Patients With and Without Comorbid Substance Use Disorder. J Autism Dev Disord 2009 39 1291-1297
10. Nylander L, Gillberg C. Screening for autism spectrum disorders in adult psychiatric out-patients: a preliminary report. Acta Psychiatr Scand 2001 103 428-434 (Pubitemid 32473034)
11. Happe F, Frith U. The weak coherence account: detail-focused cognitive style in autism spectrum disorders. J Autism Dev Disord 2006 36 5-25
12. Hill E L. van. Executive dysfunction in autism. Trends Cogn Sci 2004 8 26-32
13. Remschmidt H, Kamp-Becker I. [Neuropsychology of autistic disorders]. Fortschr Neurol Psychiatr 2005 73 654-663
14. South M, Ozonoff S, McMahon W M. The relationship between executive functioning, central coherence, and repetitive behaviors in the high-functioning autism spectrum. Autism 2007 11 437-451 (Pubitemid 47616528)
15. Happe F, Ronald A, Plomin R. Time to give up on a single explanation for autism. Nat Neurosci 2006 9 1218-1220 (Pubitemid 44454258)
16. Geschwind D H., Levitt P. Autism spectrum disorders: developmental disconnection syndromes. Curr Opin Neurobiol 2007 17 103-111 (Pubitemid 46237744)
17. Ambery F Z., Russell A J., Perry K et al. Neuropsychological functioning in adults with Asperger syndrome. Autism 2006 10 551-564 (Pubitemid 44605441)
18. Ghaziuddin M, Mountain-Kimchi K. Defining the intellectual profile of Asperger Syndrome: comparison with high-functioning autism. J Autism Dev Disord 2004 34 279-284 (Pubitemid 38860209)
19. Goldstein G, Beers S R., Siegel D J. et al. A comparison of WAIS-R profiles in adults with high-functioning autism or differing subtypes of learning disability. Appl Neuropsychol 2001 8 148-154 (Pubitemid 32976966)
20. Ozonoff S, Strayer D L. Further evidence of intact working memory in autism. J Autism Dev Disord 2001 31 257-263 (Pubitemid 37516747)
21. Kleinhans N, Akshoomoff N, Delis D C. Executive functions in autism and Aspergers disorder: flexibility, fluency, and inhibition. Dev Neuropsychol 2005 27 379-401 (Pubitemid 40712808)
22. Turner M A. Generating novel ideas: fluency performance in high-functioning and learning disabled individuals with autism. J Child Psychol Psychiatry 1999 40 189-201 (Pubitemid 29078363)
23. Happe F, Frith U. The weak coherence account: detail-focused cognitive style in autism spectrum disorders. J Autism Dev Disord 2006 36 5-25
24. Sabbagh M A. Understanding orbitofrontal contributions to theory-of-mind reasoning: implications for autism. Brain Cogn 2004 55 209-219 (Pubitemid 38591440)
25. Vogeley K, Bussfeld P, Newen A et al. Mind reading: neural mechanisms of theory of mind and self-perspective. Neuroimage 2001 14 170-181 (Pubitemid 32552753)
26. Happe F, Ehlers S, Fletcher P et al. Theory of mind in the brain. Evidence from a PET scan study of Asperger syndrome. Neuroreport 1996 8 197-201 (Pubitemid 126785558)
27. Calarge C, Andreasen N C., OLeary D S. Visualizing how one brain understands another: a PET study of theory of mind. Am J Psychiatry 2003 160 1954-1964 (Pubitemid 39619631)
28. Baron-Cohen S, Wheelwright S, Hill J et al. The Reading the Mind in the Eyes Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry 2001 42 241-251 (Pubitemid 32233124)
29. Buitelaar J K., Wees W M., Swaab-Barneveld H van der et al. Theory of mind and emotion-recognition functioning in autistic spectrum disorders and in psychiatric control and normal children. Dev Psychopathol 1999 11 39-58
30. Domes G, Kumbier E, Herpertz-Dahlmann B et al. [Social cognition in autism. A survey of functional imaging studies]. Nervenarzt 2008 79 261-274 (Pubitemid 351369251)
31. Klin A. Attributing social meaning to ambiguous visual stimuli in higher-functioning autism and Asperger syndrome: The Social Attribution Task. J Child Psychol Psychiatry 2000 41 831-846
32. David N, Gawronski A, Santos N S. et al. Dissociation between key processes of social cognition in autism: impaired mentalizing but intact sense of agency. J Autism Dev Disord 2008 38 593-605 (Pubitemid 351421874)
33. David N, Aumann C, Bewernick B H. et al. Investigation of mentalizing and visuospatial perspective taking for self and other in Asperger syndrome. J Autism Dev Disord 2010 40 290-299
34. Schwartz C, Bente G, Gawronski A et al. Responses to nonverbal behaviour of dynamic virtual characters in high-functioning autism. J Autism Dev Disord 2010 40 100-111
35. Jarrold C, Butler D W., Cottington E M. et al. Linking theory of mind and central coherence bias in autism and in the general population. Dev Psychol 2000 36 126-138
36. Howlin P, Goode S, Hutton J et al. Adult outcome for children with autism. J Child Psychol Psychiatry 2004 45 212-229 (Pubitemid 38240270)
37. Woodbury-Smith M R., Robinson J, Wheelwright S et al. Screening adults for Asperger Syndrome using the AQ: a preliminary study of its diagnostic validity in clinical practice. J Autism Dev Disord 2005 35 331-335 (Pubitemid 41125971)
38. Bruin E I., Ferdinand R F., Meester S de et al. High rates of psychiatric co-morbidity in PDD-NOS. J Autism Dev Disord 2007 37 877-886 (Pubitemid 46790785)
39. Ghaziuddin M, Ghaziuddin N, Greden J. Depression in persons with autism: implications for research and clinical care. J Autism Dev Disord 2002 32 299-306 (Pubitemid 37490179)
40. Perry D W., Marston G M., Hinder S A. et al. The phenomenology of depressive illness in people with a learning disability and autism. Autism 2001 5 265-275 (Pubitemid 32780830)
41. Stahlberg O, Soderstrom H, Rastam M et al. Bipolar disorder, schizophrenia, and other psychotic disorders in adults with childhood onset AD/HD and/or autism spectrum disorders. J Neural Transm 2004 111 891-902 (Pubitemid 38916282)
42. Stewart M E., Barnard L, Pearson J et al. Presentation of depression in autism and Asperger syndrome: a review. Autism 2006 10 103-116
43. Sinzig J, Lehmkuhl G. Autismus und ADHS Gibt es Gemeinsamkeiten? Fortschr Neurol Psychiatr 2007 75 267-274
44. Baird G, Simonoff E, Pickles A et al. Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). Lancet 2006 368 210-215 (Pubitemid 44037796)
45. Ehlers S, Nyden A, Gillberg C et al. Asperger syndrome, autism and attention disorders: a comparative study of the cognitive profiles of 120 children. J Child Psychol Psychiatry 1997 38 207-217 (Pubitemid 27095885)
46. Fombonne E. Epidemiological surveys of autism and other pervasive developmental disorders: an update. J Autism Dev Disord 2003 33 365-382 (Pubitemid 37127933)
47. Howlin P. Outcome in high-functioning adults with autism with and without early language delays: implications for the differentiation between autism and Asperger syndrome. J Autism Dev Disord 2003 33 3-13 (Pubitemid 36323135)
48. Koyama T, Tachimori H, Osada H et al. Cognitive and symptom profiles in Aspergers syndrome and high-functioning autism. Psychiatry Clin Neurosci 2007 61 99-104 (Pubitemid 46089413)
49. Frith U, Vignemont F de. Egocentrism, allocentrism, and Asperger syndrome. Conscious Cogn 2005 14 719-738 (Pubitemid 41735231)
50. Gilchrist A, Green J, Cox A et al. Development and current functioning in adolescents with Asperger syndrome: a comparative study. J Child Psychol Psychiatry 2001 42 227-240 (Pubitemid 32233123)
51. Kamp-Becker I, Smidt J, Ghahreman M et al. Categorical and dimensional structure of autism spectrum disorders: the nosologic validity of Asperger Syndrome. J Autism Dev Disord 2010 40 921-929
52. Baron-Cohen S, Wheelwright S, Skinner R et al. The autism-spectrum quotient (AQ): evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. J Autism Dev Disord 2001 31 5-17
53. Lord C, Rutter M, Le Couteur A. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994 24 659-685 (Pubitemid 24309810)
54. Tewes U. Hamburg-Wechsler Intelligenztest für Erwachsene, Revision. Bern Verlag Huber 1991
55. Loonstra A S., Tarlow A R., Sellers A H. COWAT metanorms across age, education, and gender. Appl Neuropsychol 2001 8 161-166 (Pubitemid 32976968)
56. Kalbe E, Adenauer H, Brand M et al. Die Erfassung von Theory-of-Mind-Defiziten bei Menschen mit Asperger-Syndrom: Ein Vergleich deutschsprachiger Testverfahren. Der Nervenarzt 2005 76 (Suppl. 1) 220
57. Beck A, Ward C, Mendelson M et al. An Inventory for Measuring Depression. Archives of General Psychiatry 1961 4 561-571
58. Remschmidt H, Kamp-Becker I. Asperger-Syndrom. Heidelberg Springer Medizin Verlag 2006
59. Billstedt E, Gillberg I C., Gillberg C. Autism in adults: symptom patterns and early childhood predictors. Use of the DISCO in a community sample followed from childhood. J Child Psychol Psychiatry 2007 48 1102-1110 (Pubitemid 350086153)
60. Spek A, Schatorje T, Scholte E et al. Verbal fluency in adults with high functioning autism or Asperger syndrome. Neuropsychologia 2009 47 652-656
61. Spek A A., Scholte E M., Berckelaer-Onnes I A. Brief report: The use of WAIS-III in adults with HFA and Asperger syndrome. J Autism Dev Disord 2008 38 782-787 (Pubitemid 351421892)
62. Engel R, Kessler J, Satzger W. PC-spezifische Verfahren in der Psychodiagnostik: Überblick und Darstellung neuer Verfahren. Bericht über den 38.Kongress der Deutschen Gesellschaft für Psychologie Trier 1992 Göttingen Hofgrefe 1993 863-866
63. Lopez B R., Lincoln A J., Ozonoff S et al. Examining the relationship between executive functions and restricted, repetitive symptoms of Autistic Disorder. J Autism Dev Disord 2005 35 445-460 (Pubitemid 41216431)
64. Sergeant J A., Geurts H, Oosterlaan J. How specific is a deficit of executive functioning for attention-deficit/hyperactivity disorder? Behav Brain Res 2002 130 3-28 (Pubitemid 34195317)
65. Bolte S, Poustka F. [Psychodiagnostic instruments for the assessment of autism spectrum disorders]. Z Kinder Jugendpsychiatr Psychother 2005 33 5-14
66. Lehmkuhl G. [How specific are neuropsychological functions in autism? Fortschr Neurol Psychiatr 2005 73 651-653 (Pubitemid 41704240)