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Volumn 121, Issue 5, 2011, Pages 1753-1767

Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN; PROTEIN TFF1; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

EID: 79955509042     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI43922     Document Type: Article
Times cited : (100)

References (47)
  • 1
    • 0023690989 scopus 로고
    • A human model of gastric carcinogenesis
    • Correa P. A human model of gastric carcinogenesis. Cancer Res. 1988;48(13):3554-3560.
    • (1988) Cancer Res , vol.48 , Issue.13 , pp. 3554-3560
    • Correa, P.1
  • 2
    • 29344441525 scopus 로고    scopus 로고
    • Structure of mammalian trefoil factors and functional insights
    • DOI 10.1007/s00018-005-5484-6
    • Thim L, May FE. Structure of mammalian trefoil factors and functional insights. Cell Mol Life Sci. 2005;62(24):2956-2973. (Pubitemid 43004748)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.24 , pp. 2956-2973
    • Thim, L.1    May, F.E.B.2
  • 3
    • 0032547383 scopus 로고    scopus 로고
    • The pS2/TFF1 trefoil factor, from basic research to clinical applications
    • DOI 10.1016/S0304-419X(98)00016-X, PII S0304419X9800016X
    • Ribieras S, Tomasetto C, Rio MC. The pS2/TFF1 trefoil factor, from basic research to clinical applications. Biochim Biophys Acta. 1998;1378(1):F61-F77. (Pubitemid 28381126)
    • (1998) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1378 , Issue.1
    • Ribieras, S.1    Tomasetto, C.2    Rio, M.-C.3
  • 4
    • 33645212423 scopus 로고    scopus 로고
    • Cytosolic levels of TFF1/pS2 in breast cancer: Their relationship with clinical-pathological parameters and their prognostic significance
    • Corte MD, et al. Cytosolic levels of TFF1/pS2 in breast cancer: Their relationship with clinical-pathological parameters and their prognostic significance. Breast Cancer Res Treat. 2006;96(1):63-72.
    • (2006) Breast Cancer Res Treat , vol.96 , Issue.1 , pp. 63-72
    • Corte, M.D.1
  • 5
    • 0023769895 scopus 로고
    • Breast cancer-associated pS2 protein: Synthesis and secretion by normal stomach mucosa
    • Rio MC, et al. Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science. 1988;241(4866):705-708.
    • (1988) Science , vol.241 , Issue.4866 , pp. 705-708
    • Rio, M.C.1
  • 6
    • 0035083916 scopus 로고    scopus 로고
    • Augmented intestinal trefoil factor (TFF3) and loss of pS2 (TFF1) expression precedes metaplastic differentiation of gastric epithelium
    • Taupin D, Pedersen J, Familari M, Cook G, Yeomans N, Giraud AS. Augmented intestinal trefoil factor (TFF3) and loss of pS2 (TFF1) expression precedes metaplastic differentiation of gastric epithelium. Lab Invest. 2001;81(3):397-408. (Pubitemid 32245071)
    • (2001) Laboratory Investigation , vol.81 , Issue.3 , pp. 397-408
    • Taupin, D.1    Pedersen, J.2    Familari, M.3    Cook, G.4    Yeomans, N.5    Giraud, A.S.6
  • 8
    • 1542599176 scopus 로고    scopus 로고
    • Trefoil factors and human gastric cancer
    • review
    • Katoh M. Trefoil factors and human gastric cancer (review). Int J Mol Med. 2003;12(1):3-9.
    • (2003) Int J Mol Med , vol.12 , Issue.1 , pp. 3-9
    • Katoh, M.1
  • 9
    • 32944460414 scopus 로고    scopus 로고
    • Cofactor of BRCA1: A novel transcription factor regulator in upper gastrointestinal adenocarcinomas
    • DOI 10.1158/0008-5472.CAN-05-3593
    • McChesney PA, et al. Cofactor of BRCA1: a novel transcription factor regulator in upper gastrointestinal adenocarcinomas. Cancer Res. 2006; 66(3):1346-1353. (Pubitemid 43259913)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1346-1353
    • McChesney, P.A.1    Aiyar, S.E.2    Lee, O.-J.3    Zaika, A.4    Moskaluk, C.5    Li, R.6    El-Rifai, W.7
  • 10
    • 0034676243 scopus 로고    scopus 로고
    • Mapping of a new target region of allelic loss at 21q22 in primary gastric cancers
    • Park WS, et al. Mapping of a new target region of allelic loss at 21q22 in primary gastric cancers. Cancer Lett. 2000;159(1):15-21.
    • (2000) Cancer Lett , vol.159 , Issue.1 , pp. 15-21
    • Park, W.S.1
  • 11
    • 0035925539 scopus 로고    scopus 로고
    • Mouse Trefoil Factor genes: Genomic organization, sequences and methylation analyses
    • DOI 10.1016/S0378-1119(01)00380-8, PII S0378111901003808
    • Ribieras S, Lefebvre O, Tomasetto C, Rio MC. Mouse Trefoil factor genes: genomic organization, sequences and methylation analyses. Gene. 2001; 266(1-2):67-75. (Pubitemid 32268657)
    • (2001) Gene , vol.266 , Issue.1-2 , pp. 67-75
    • Ribieras, S.1    Lefebvre, O.2    Tomasetto, C.3    Rio, M.-C.4
  • 12
    • 0033952575 scopus 로고    scopus 로고
    • DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis
    • DOI 10.1016/S0304-3835(99)00349-3, PII S0304383599003493
    • Fujimoto J, Yasui W, Tahara H, Tahara E, Kudo Y, Yokozaki H. DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis. Cancer Lett. 2000;149(1-2):125-134. (Pubitemid 30100568)
    • (2000) Cancer Letters , vol.149 , Issue.1-2 , pp. 125-134
    • Fujimoto, J.1    Yasui, W.2    Tahara, H.3    Tahara, E.4    Kudo, Y.5    Yokozaki, H.6    Tahara, E.7
  • 13
    • 79952311137 scopus 로고    scopus 로고
    • Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing
    • published online ahead of print November 25, 2010. doi: 10.1053/j.gastro.2010.11.037
    • Tomita H, et al. Inhibition of gastric carcinogenesis by the hormone, gastrin, is mediated by suppression of TFF1 epigenetic silencing [published online ahead of print November 25, 2010]. Gastroenterology. doi: 10.1053/j.gastro.2010.11.037.
    • Gastroenterology
    • Tomita, H.1
  • 14
    • 0033857454 scopus 로고    scopus 로고
    • Somatic mutations of the trefoil factor family 1 gene in gastric cancer
    • Park WS, et al. Somatic mutations of the trefoil factor family 1 gene in gastric cancer. Gastroenterology. 2000;119(3):691-698.
    • (2000) Gastroenterology , vol.119 , Issue.3 , pp. 691-698
    • Park, W.S.1
  • 15
    • 15744380422 scopus 로고    scopus 로고
    • Transcriptional repression of TFF1 in gastric epithelial cells by CCAAT/enhancer binding protein-beta
    • DOI 10.1016/j.bbaexp.2004.12.014
    • Sankpal NV, Mayo MW, Powell SM. Transcriptional repression of TFF1 in gastric epithelial cells by CCAAT/enhancer binding protein-beta. Biochim Biophys Acta. 2005;1728(1-2):1-10. (Pubitemid 40409950)
    • (2005) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1728 , Issue.1-2 , pp. 1-10
    • Sankpal, N.V.1    Mayo, M.W.2    Powell, S.M.3
  • 16
    • 0032980531 scopus 로고    scopus 로고
    • The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line ags
    • DOI 10.1002/(SICI)1096-9896(199907)188:3<312::AID-PATH360>3.0.CO;2- P
    • Calnan DP, Westley BR, May FE, Floyd DN, March-bank T, Playford RJ. The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS. J Pathol. 1999;188(3):312-317. (Pubitemid 29317776)
    • (1999) Journal of Pathology , vol.188 , Issue.3 , pp. 312-317
    • Calnan, D.P.1    Westley, B.R.2    May, F.E.B.3    Floyd, D.N.4    Marchbank, T.5    Playford, R.J.6
  • 18
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB - A pivotal transcription factor in chronic inflammatory diseases
    • DOI 10.1056/NEJM199704103361506
    • Barnes PJ, Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997;336(15):1066-1071. (Pubitemid 27163860)
    • (1997) New England Journal of Medicine , vol.336 , Issue.15 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 19
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
    • DOI 10.1016/j.cell.2006.02.016, PII S0092867406001917
    • Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 2006;124(4):823-835. (Pubitemid 43261455)
    • (2006) Cell , vol.124 , Issue.4 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 20
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • DOI 10.1038/nature04870, PII NATURE04870
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature. 2006; 441(7092):431-436. (Pubitemid 44050137)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 431-436
    • Karin, M.1
  • 21
    • 40249109853 scopus 로고    scopus 로고
    • The IkB kinase - A bridge between inflammation and cancer
    • DOI 10.1038/cr.2008.30, PII CR200830
    • Karin M. The IkappaB kinase - a bridge between inf lammation and cancer. Cell Res. 2008; 18(3):334-342. (Pubitemid 351333897)
    • (2008) Cell Research , vol.18 , Issue.3 , pp. 334-342
    • Karin, M.1
  • 22
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
    • Greten FR, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 2004;118(3):285-296. (Pubitemid 39061110)
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.-W.5    Egan, L.J.6    Kagnoff, M.F.7    Karin, M.8
  • 23
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • DOI 10.1038/nri1703
    • Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol. 2005;5(10):749-759. (Pubitemid 41400849)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 24
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-kappaB signaling: Balancing life and death - A new approach to cancer therapy
    • DOI 10.1172/JCI26322
    • Luo JL, Kamata H, Karin M. IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy. J Clin Invest. 2005;115(10):2625-2632. (Pubitemid 41434385)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2625-2632
    • Luo, J.-L.1    Kamata, H.2    Karin, M.3
  • 26
    • 77950838790 scopus 로고    scopus 로고
    • Disruption of NF-kappaB signalling by ancient microbial molecules: Novel therapies of the future?
    • Yan F, Polk DB. Disruption of NF-kappaB signalling by ancient microbial molecules: novel therapies of the future? Gut. 2010;59(4):421-426.
    • (2010) Gut , vol.59 , Issue.4 , pp. 421-426
    • Yan, F.1    Polk, D.B.2
  • 27
    • 0030271387 scopus 로고    scopus 로고
    • NF-kappa B: Ten years after
    • Baeuerle PA, Baltimore D. NF-kappa B: ten years after. Cell. 1996;87(1):13-20.
    • (1996) Cell , vol.87 , Issue.1 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 28
    • 37449033866 scopus 로고    scopus 로고
    • Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation
    • DOI 10.1016/j.cyto.2007.09.016, PII S1043466607004528
    • Li H, Lin X. Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation. Cytokine. 2008;41(1):1-8. (Pubitemid 50012147)
    • (2008) Cytokine , vol.41 , Issue.1 , pp. 1-8
    • Li, H.1    Lin, X.2
  • 29
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Häcker H, Karin M. Regulation and function of IKK and IKK-related kinases. Sci STKE. 2006; 2006(357):re13.
    • (2006) Sci STKE , vol.2006 , Issue.357
    • Häcker, H.1    Karin, M.2
  • 30
    • 0030447483 scopus 로고    scopus 로고
    • The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
    • Shu HB, Takeuchi M, Goeddel DV. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc Natl Acad Sci U S A. 1996;93(24):13973-13978.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.24 , pp. 13973-13978
    • Shu, H.B.1    Takeuchi, M.2    Goeddel, D.V.3
  • 31
    • 0027228534 scopus 로고
    • Spasmolytic polypeptide is a major antral peptide: Distribution of the trefoil peptides human spasmolytic polypeptide and pS2 in the stomach
    • Hanby AM, Poulsom R, Singh S, Elia G, Jeffery RE, Wright NA. Spasmolytic polypeptide is a major antral peptide: distribution of the trefoil peptides human spasmolytic polypeptide and pS2 in the stomach. Gastroenterology. 1993;105(4):1110-1116. (Pubitemid 23281500)
    • (1993) Gastroenterology , vol.105 , Issue.4 , pp. 1110-1116
    • Hanby, A.M.1    Poulsom, R.2    Singh, S.3    Elia, G.4    Jeffery, R.E.5    Wright, N.A.6
  • 33
    • 20144362549 scopus 로고    scopus 로고
    • Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C
    • DOI 10.1021/bi047287n
    • Westley BR, Griffin SM, May FE. Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C. Biochemistry. 2005; 44(22):7967-7975. (Pubitemid 40776657)
    • (2005) Biochemistry , vol.44 , Issue.22 , pp. 7967-7975
    • Westley, B.R.1    Griffin, S.M.2    May, F.E.B.3
  • 34
    • 0034009433 scopus 로고    scopus 로고
    • Nonsteroidal. anti-inflammatory drugs and cancer prevention
    • DOI 10.1146/annurev.med.51.1.511
    • Baron JA, Sandler RS. Nonsteroidal anti-inflammatory drugs and cancer prevention. Annu Rev Med. 2000;51:511-523. (Pubitemid 30216052)
    • (2000) Annual Review of Medicine , vol.51 , pp. 511-523
    • Baron, J.A.1    Sandler, R.S.2
  • 35
    • 33845981808 scopus 로고    scopus 로고
    • Inflammation, atrophy, and gastric cancer
    • DOI 10.1172/JCI30111
    • Fox JG, Wang TC. Inflammation, atrophy, and gastric cancer. J Clin Invest. 2007;117(1):60-69. (Pubitemid 46048450)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.1 , pp. 60-69
    • Fox, J.G.1    Wang, T.C.2
  • 36
    • 5644257293 scopus 로고    scopus 로고
    • Age-promoted creation of a pro-cancer microenvironment by inflammation: Pathogenesis of dyscoordinated feedback control
    • DOI 10.1016/j.mad.2004.08.003, PII S0047637404001538
    • Schwartsburd PM. Age-promoted creation of a pro-cancer microenvironment by inflammation: pathogenesis of dyscoordinated feedback control. Mech Ageing Dev. 2004;125(9):581-590. (Pubitemid 39371152)
    • (2004) Mechanisms of Ageing and Development , vol.125 , Issue.9 , pp. 581-590
    • Schwartsburd, P.M.1
  • 37
    • 67649655932 scopus 로고    scopus 로고
    • Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4
    • Murphy G, et al. Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4. Eur J Gastroenterol Hepatol. 2009;21(6):630-635.
    • (2009) Eur J Gastroenterol Hepatol , vol.21 , Issue.6 , pp. 630-635
    • Murphy, G.1
  • 39
    • 54549089856 scopus 로고    scopus 로고
    • Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
    • Tu S, et al. Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell. 2008;14(5):408-419.
    • (2008) Cancer Cell , vol.14 , Issue.5 , pp. 408-419
    • Tu, S.1
  • 40
    • 67650376399 scopus 로고    scopus 로고
    • The NF-kappaB transcription factor pathway as a therapeutic target in cancer: Methods for detection of NF-kappaB activity
    • Mauro C, Zazzeroni F, Papa S, Bubici C, Franzoso G. The NF-kappaB transcription factor pathway as a therapeutic target in cancer: methods for detection of NF-kappaB activity. Methods Mol Biol. 2009; 512:169-207.
    • (2009) Methods Mol Biol , vol.512 , pp. 169-207
    • Mauro, C.1    Zazzeroni, F.2    Papa, S.3    Bubici, C.4    Franzoso, G.5
  • 41
    • 34247895504 scopus 로고    scopus 로고
    • AP1- and NF-kappaB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFalpha-WNT10B signaling loop implicated in carcinogenesis and adipogenesis
    • Katoh M. AP1- and NF-kappaB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFalpha-WNT10B signaling loop implicated in carcinogenesis and adipogenesis. Int J Mol Med. 2007;19(4):699-703.
    • (2007) Int J Mol Med , vol.19 , Issue.4 , pp. 699-703
    • Katoh, M.1
  • 43
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry RA, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4(2):249-264.
    • (2003) Biostatistics , vol.4 , Issue.2 , pp. 249-264
    • Irizarry, R.A.1
  • 44
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3:Article3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 45
    • 70149113077 scopus 로고    scopus 로고
    • R Development Core Team. Vienna, Austria: R Foundation for Statistical Computing
    • R Development Core Team. R: A Language And Environment For Statistical Computing. Vol. 1. Vienna, Austria: R Foundation for Statistical Computing; 2009.
    • (2009) R: A Language and Environment for Statistical Computing , vol.1
  • 47
    • 77955299406 scopus 로고    scopus 로고
    • Dopamine and cAMP regulated phosphoprotein MW 32 kDa is overexpressed in early stages of gastric tumorigenesis
    • Mukherjee K, et al. Dopamine and cAMP regulated phosphoprotein MW 32 kDa is overexpressed in early stages of gastric tumorigenesis. Surgery. 2010; 148(2):354-363.
    • (2010) Surgery , vol.148 , Issue.2 , pp. 354-363
    • Mukherjee, K.1


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