Mouse Trefoil Factor genes: Genomic organization, sequences and methylation analyses

Gene

Volumn 266, Issue 1-2, 2001, Pages 67-75

  Ribieras, Stéphane ^a   Lefèbvre, Olivier ^b   Tomasetto, Catherine ^a   Rio, Marie Christine ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSERM   (France)

Author keywords

DNA methylation; Epigenetic regulation; Gene cluster; TFF1 pS2; TFF2 SP; TFF3 ITF

Indexed keywords

TREFOIL PEPTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; GASTROINTESTINAL TRACT; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENE STRUCTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION; REACTION ANALYSIS; SEQUENCE HOMOLOGY;

ANIMALS; BASE SEQUENCE; DNA; GENE EXPRESSION; GENES; GROWTH SUBSTANCES; MICE; MOLECULAR SEQUENCE DATA; MUCINS; MUSCLE PROTEINS; NEUROPEPTIDES; PEPTIDES; PROMOTER REGIONS (GENETICS); RNA; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, NUCLEIC ACID; TISSUE DISTRIBUTION;

LOTUS; MAMMALIA;

EID: 0035925539     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(01)00380-8     Document Type: Article

References (37)

1. Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats
2. 5′-Flanking motifs control cell-specific expression of the trefoil factor genes (TFF)
3. Hepathocyte Nuclear Factor 3 (Winged Helix Domain) activates Trefoil factor gene TFF1 through a binding motif adjacent to the TATAA box
4. The trefoil gene maps to mouse chromosome 17
5. Combined intestinal trefoil factor and epidermal growth factor is prophylactic against indomethacin-induced gastric damage in the rat
6. The gene encoding human intestinal trefoil factor (TFF3) is located on chromosome 21q22.3 clustered with other members of the trefoil peptide family
7. The gene encoding mouse intestinal trefoil factor: Structural organization, partial sequence analysis and mapping to murine chromosome 17q
8. Transmembrane domain length variation in the evolution of major histocompatibility complex class I genes
9. DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis
10. Human trefoil peptides: Genomic structure in 21q22.3 and coordinated expression
11. xP2, a new member of the P-domain peptide family of potential growth factor, is expressed in Xenopus laevis skin
12. Structure of the human oestrogen-responsive gene pS2
13. The DNA methylation paradox
14. A novel 25 bp tandem repeat within the human trefoil peptide gene TFF2 in 21q22.3: Polymorphism and mammalian evolution
15. Trefoil peptide protection of intestinal epithelial barrier function: Cooperative interaction with mucin glycoprotein
16. The mouse one P-domain (pS2) and two P-domain (mSP) genes exhibit distinct patterns of expression
17. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein
18. CCAAT-enhancer-binding proteins (C/EBP) regulate the tissue specific activity of the CD11c integrin gene promoter through functional interactions with Sp1 proteins
19. Involvement of DNA methylation in the control of the expression of an estrogen-induced breast-cancer-associated protein (pS2) in human breast cancers
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21. Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor
22. Cloning of cDNA sequences of hormone-regulated genes from the MCF7 human breast cancer cell line
23. Close physical linkage of the genes encoding the pNR-2/pS2 protein and human spasmolytic protein (hSP)
24. Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage
25. Human breast and colon cancers exhibit alterations of DNA methylation patterns at several DNA segments on chromosomes 11p and 17p
26. The pS2/TFF1 trefoil factor, from basic research to clinical applications
27. Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract
28. Klf4 is a transcription factor required for establishing the barrier function of the skin
29. Characterization of the genomic structure and the promoter region of the human intestinal trefoil factor
30. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop
31. Regulation and function of DNA methylation in vertebrates
32. Trefoil peptides: From structure to function
33. hSP, the domain-duplicated homolog of pS2 protein, is co-expressed with pS2 in stomach but not in breast carcinoma
34. The gene encoding the human spasmolytic protein (SML1/hSP) is in 21q22.3, physically linked to the homologous breast cancer marker gene BCEI/pS2
35. Expression of the gut-enriched Kruppel-like factor gene during development and intestinal tumorigenesis
36. Epigenetics: Regulation through repression
37. Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease