메뉴 건너뛰기




Volumn 54, Issue 4, 2011, Pages 300-310

Genes and regulatory networks involved in persistence of Mycobacterium tuberculosis

Author keywords

dormancy; Mycobacterium tuberculosis; network; persistent infection

Indexed keywords

TUBERCULOSTATIC AGENT;

EID: 79955484287     PISSN: 16747305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11427-011-4134-5     Document Type: Review
Times cited : (19)

References (71)
  • 1
    • 0037296604 scopus 로고    scopus 로고
    • Molecular mechanisms regulating persistent Mycobacterium tuberculosis infection
    • Zahrt T C. Molecular mechanisms regulating persistent Mycobacterium tuberculosis infection. Microbes Infect, 2003, 5: 159-167.
    • (2003) Microbes Infect , vol.5 , pp. 159-167
    • Zahrt, T.C.1
  • 2
    • 0342794213 scopus 로고    scopus 로고
    • Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
    • McKinney J D, Honer zu Bentrup K, Munoz-Elias E J, et al. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase. Nature, 2000, 406: 735-738.
    • (2000) Nature , vol.406 , pp. 735-738
    • McKinney, J.D.1    Honer zu, B.K.2    Munoz-Elias, E.J.3
  • 3
    • 0019973896 scopus 로고
    • Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions
    • Wayne L G, Lin K Y. Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions. Infect Immun, 1982, 37: 1042-1049.
    • (1982) Infect Immun , vol.37 , pp. 1042-1049
    • Wayne, L.G.1    Lin, K.Y.2
  • 4
    • 0036139212 scopus 로고    scopus 로고
    • Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific
    • Fritz C, Maass S, Kreft A, et al. Dependence of Mycobacterium bovis BCG on anaerobic nitrate reductase for persistence is tissue specific. Infect Immun, 2002, 70: 286-291.
    • (2002) Infect Immun , vol.70 , pp. 286-291
    • Fritz, C.1    Maass, S.2    Kreft, A.3
  • 5
    • 0034662486 scopus 로고    scopus 로고
    • Analysis of the dormancy-inducible narK2 promoter in Mycobacterium bovis BCG
    • Hutter B, Dick T. Analysis of the dormancy-inducible narK2 promoter in Mycobacterium bovis BCG. FEMS Microbiol Lett, 2000, 188: 141-146.
    • (2000) FEMS Microbiol Lett , vol.188 , pp. 141-146
    • Hutter, B.1    Dick, T.2
  • 6
    • 0033634971 scopus 로고    scopus 로고
    • A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis
    • Glickman M S, Cox J S, Jacobs W R Jr. A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis. Mol Cell, 2000, 5: 717-727.
    • (2000) Mol Cell , vol.5 , pp. 717-727
    • Glickman, M.S.1    Cox, J.S.2    Jacobs Jr., W.R.3
  • 7
    • 17644373124 scopus 로고    scopus 로고
    • The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis
    • Murphy H N, Stewart G R, Mischenko V V, et al. The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis. J Biol Chem, 2005, 280: 14524-14529.
    • (2005) J Biol Chem , vol.280 , pp. 14524-14529
    • Murphy, H.N.1    Stewart, G.R.2    Mischenko, V.V.3
  • 8
    • 0035940419 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis signal transduction system required for persistent infections
    • Zahrt T C, Deretic V. Mycobacterium tuberculosis signal transduction system required for persistent infections. Proc Natl Acad Sci USA, 2001, 98: 12706-12711.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12706-12711
    • Zahrt, T.C.1    Deretic, V.2
  • 9
    • 0037371176 scopus 로고    scopus 로고
    • Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis
    • Parish T, Smith D A, Kendall S, et al. Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis. Infect Immun, 2003, 71: 1134-1140.
    • (2003) Infect Immun , vol.71 , pp. 1134-1140
    • Parish, T.1    Smith, D.A.2    Kendall, S.3
  • 10
    • 0033805703 scopus 로고    scopus 로고
    • Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF
    • Chen P, Ruiz R E, Li Q, et al. Construction and characterization of a Mycobacterium tuberculosis mutant lacking the alternate sigma factor gene, sigF. Infect Immun, 2000, 68: 5575-5580.
    • (2000) Infect Immun , vol.68 , pp. 5575-5580
    • Chen, P.1    Ruiz, R.E.2    Li, Q.3
  • 11
    • 0037062452 scopus 로고    scopus 로고
    • Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH
    • Kaushal D, Schroeder B G, Tyagi S, et al. Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH. Proc Natl Acad Sci USA, 2002, 99: 8330-8335.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8330-8335
    • Kaushal, D.1    Schroeder, B.G.2    Tyagi, S.3
  • 12
    • 0345283047 scopus 로고    scopus 로고
    • Deletion of Mycobacterium tuberculosis sigma factor E results in delayed time to death with bacterial persistence in the lungs of aerosol-infected mice
    • Ando M, Yoshimatsu T, Ko C, et al. Deletion of Mycobacterium tuberculosis sigma factor E results in delayed time to death with bacterial persistence in the lungs of aerosol-infected mice. Infect Immun, 2003, 71: 7170-7172.
    • (2003) Infect Immun , vol.71 , pp. 7170-7172
    • Ando, M.1    Yoshimatsu, T.2    Ko, C.3
  • 13
    • 0037022605 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth
    • Steyn A J, Collins D M, Hondalus M K, et al. Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth. Proc Natl Acad Sci USA, 2002, 99: 3147-3152.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3147-3152
    • Steyn, A.J.1    Collins, D.M.2    Hondalus, M.K.3
  • 14
    • 0033872759 scopus 로고    scopus 로고
    • The stringent response of Mycobacterium tuberculosis is required for long-term survival
    • Primm T P, Andersen S J, Mizrahi V, et al. The stringent response of Mycobacterium tuberculosis is required for long-term survival. J Bacteriol, 2000, 182: 4889-4898.
    • (2000) J Bacteriol , vol.182 , pp. 4889-4898
    • Primm, T.P.1    Andersen, S.J.2    Mizrahi, V.3
  • 15
    • 31844449080 scopus 로고    scopus 로고
    • Deletion of the Mycobacterium tuberculosis alpha-crystallin-like hspX gene causes increased bacterial growth in vivo
    • Hu Y, Movahedzadeh F, Stoker N G, et al. Deletion of the Mycobacterium tuberculosis alpha-crystallin-like hspX gene causes increased bacterial growth in vivo. Infect Immun, 2006, 74: 861-868.
    • (2006) Infect Immun , vol.74 , pp. 861-868
    • Hu, Y.1    Movahedzadeh, F.2    Stoker, N.G.3
  • 16
    • 0034948578 scopus 로고    scopus 로고
    • Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection
    • Stewart G R, Snewin V A, Walzl G, et al. Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection. Nat Med, 2001, 7: 732-737.
    • (2001) Nat Med , vol.7 , pp. 732-737
    • Stewart, G.R.1    Snewin, V.A.2    Walzl, G.3
  • 17
    • 0031957229 scopus 로고    scopus 로고
    • Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs
    • Li Z, Kelley C, Collins F, et al. Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs. J Infect Dis, 1998, 177: 1030-1035.
    • (1998) J Infect Dis , vol.177 , pp. 1030-1035
    • Li, Z.1    Kelley, C.2    Collins, F.3
  • 18
    • 33746528061 scopus 로고    scopus 로고
    • Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis
    • Gould T A, van de Langemheen H, Munoz-Elias E J, et al. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis. Mol Microbiol, 2006, 61: 940-947.
    • (2006) Mol Microbiol , vol.61 , pp. 940-947
    • Gould, T.A.1    van de Langemheen, H.2    Munoz-Elias, E.J.3
  • 19
    • 47349113938 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis isocitrate lyase (MtbIcl): Role of divalent cations in modulation of functional and structural properties
    • Kumar R, Bhakuni V. Mycobacterium tuberculosis isocitrate lyase (MtbIcl): Role of divalent cations in modulation of functional and structural properties. Proteins, 2008, 72: 892-900.
    • (2008) Proteins , vol.72 , pp. 892-900
    • Kumar, R.1    Bhakuni, V.2
  • 20
    • 0032453525 scopus 로고    scopus 로고
    • Nitrate reduction as a marker for hypoxic shiftdown of Mycobacterium tuberculosis
    • Wayne L G, Hayes L G. Nitrate reduction as a marker for hypoxic shiftdown of Mycobacterium tuberculosis. Tuber Lung Dis, 1998, 79: 127-132.
    • (1998) Tuber Lung Dis , vol.79 , pp. 127-132
    • Wayne, L.G.1    Hayes, L.G.2
  • 21
    • 57449084698 scopus 로고    scopus 로고
    • Differences in nitrate reduction between Mycobacterium tuberculosis and Mycobacterium bovis are due to differential expression of both narGHJI and narK2
    • Sohaskey C D, Modesti L. Differences in nitrate reduction between Mycobacterium tuberculosis and Mycobacterium bovis are due to differential expression of both narGHJI and narK2. FEMS Microbiol Lett, 2009, 290: 129-134.
    • (2009) FEMS Microbiol Lett , vol.290 , pp. 129-134
    • Sohaskey, C.D.1    Modesti, L.2
  • 22
    • 27744462809 scopus 로고    scopus 로고
    • Regulation of nitrate reductase activity in Mycobacterium tuberculosis by oxygen and nitric oxide
    • Sohaskey C D. Regulation of nitrate reductase activity in Mycobacterium tuberculosis by oxygen and nitric oxide. Microbiology, 2005, 151: 3803-3810.
    • (2005) Microbiology , vol.151 , pp. 3803-3810
    • Sohaskey, C.D.1
  • 23
    • 0035584286 scopus 로고    scopus 로고
    • Mycobacterial persistence: Adaptation to a changing environment
    • Honer zu Bentrup K, Russell D G. Mycobacterial persistence: Adaptation to a changing environment. Trends Microbiol, 2001, 9: 597-605.
    • (2001) Trends Microbiol , vol.9 , pp. 597-605
    • Honer zu, B.K.1    Russell, D.G.2
  • 24
    • 0344666693 scopus 로고    scopus 로고
    • Role of narK2X and narGHJI in hypoxic upregulation of nitrate reduction by Mycobacterium tuberculosis
    • Sohaskey C D, Wayne L G. Role of narK2X and narGHJI in hypoxic upregulation of nitrate reduction by Mycobacterium tuberculosis. J Bacteriol, 2003, 185: 7247-7256.
    • (2003) J Bacteriol , vol.185 , pp. 7247-7256
    • Sohaskey, C.D.1    Wayne, L.G.2
  • 25
    • 33745217856 scopus 로고    scopus 로고
    • Trans-cyclopropanation of mycolic ac ids on trehalose dimycolate suppresses Mycobacterium tuberculosis-induced inflammation and virulence
    • Rao V, Gao F, Chen B, et al. Trans-cyclopropanation of mycolic ac ids on trehalose dimycolate suppresses Mycobacterium tuberculosis-induced inflammation and virulence. J Clin Invest, 2006, 116: 1660-1667.
    • (2006) J Clin Invest , vol.116 , pp. 1660-1667
    • Rao, V.1    Gao, F.2    Chen, B.3
  • 26
    • 0033972606 scopus 로고    scopus 로고
    • Three pathways for trehalose biosynthesis in mycobacteria
    • De Smet K A, Weston A, Brown I N, et al. Three pathways for trehalose biosynthesis in mycobacteria. Microbiology, 2000, 146: 199-208.
    • (2000) Microbiology , vol.146 , pp. 199-208
    • de Smet, K.A.1    Weston, A.2    Brown, I.N.3
  • 27
    • 33645450141 scopus 로고    scopus 로고
    • Trehalose 6,6′-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice
    • Hunter R L, Olsen M, Jagannath C, et al. Trehalose 6, 6′-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice. Am J Pathol, 2006, 168: 1249-1261.
    • (2006) Am J Pathol , vol.168 , pp. 1249-1261
    • Hunter, R.L.1    Olsen, M.2    Jagannath, C.3
  • 28
    • 0035663960 scopus 로고    scopus 로고
    • Immunological properties of trehalose dimycolate (cord factor) and other mycolic acid-containing glycolipids-a review
    • Ryll R, Kumazawa Y, Yano I. Immunological properties of trehalose dimycolate (cord factor) and other mycolic acid-containing glycolipids-a review. Microbiol Immunol, 2001, 45: 801-811.
    • (2001) Microbiol Immunol , vol.45 , pp. 801-811
    • Ryll, R.1    Kumazawa, Y.2    Yano, I.3
  • 29
    • 33747068254 scopus 로고    scopus 로고
    • The role of trehalose dimycolate (cord factor) on morphology of virulent M. tuberculosis in vitro
    • Hunter R L, Venkataprasad N, Olsen M R. The role of trehalose dimycolate (cord factor) on morphology of virulent M. tuberculosis in vitro. Tuberculosis (Edinb), 2006, 86: 349-356.
    • (2006) Tuberculosis (Edinb) , vol.86 , pp. 349-356
    • Hunter, R.L.1    Venkataprasad, N.2    Olsen, M.R.3
  • 30
    • 58249106846 scopus 로고    scopus 로고
    • Trehalose 6,6'-dimycolate on the surface of Mycobacterium tuberculosis modulates surface marker expression for antigen presentation and costimulation in murine macrophages
    • Kan-Sutton C, Jagannath C, Hunter R L Jr. Trehalose 6, 6'-dimycolate on the surface of Mycobacterium tuberculosis modulates surface marker expression for antigen presentation and costimulation in murine macrophages. Microbes Infect, 2009, 11: 40-48.
    • (2009) Microbes Infect , vol.11 , pp. 40-48
    • Kan-Sutton, C.1    Jagannath, C.2    Hunter Jr., R.L.3
  • 31
    • 33644857465 scopus 로고    scopus 로고
    • MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis
    • He H, Hovey R, Kane J, et al. MprAB is a stress-responsive two-component system that directly regulates expression of sigma factors SigB and SigE in Mycobacterium tuberculosis. J Bacteriol, 2006, 188: 2134-2143.
    • (2006) J Bacteriol , vol.188 , pp. 2134-2143
    • He, H.1    Hovey, R.2    Kane, J.3
  • 32
    • 34247245826 scopus 로고    scopus 로고
    • Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant of Mycobacterium tuberculosis
    • Pang X, Vu P, Byrd T F, et al. Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant of Mycobacterium tuberculosis. Microbiology, 2007, 153: 1229-1242.
    • (2007) Microbiology , vol.153 , pp. 1229-1242
    • Pang, X.1    Vu, P.2    Byrd, T.F.3
  • 33
    • 0034903883 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis ECF sigma factor sigmaE: Role in global gene expression and survival in macrophages
    • Manganelli R, Voskuil M I, Schoolnik G K, et al. The Mycobacterium tuberculosis ECF sigma factor sigmaE: Role in global gene expression and survival in macrophages. Mol Microbiol, 2001, 41: 423-437.
    • (2001) Mol Microbiol , vol.41 , pp. 423-437
    • Manganelli, R.1    Voskuil, M.I.2    Schoolnik, G.K.3
  • 34
    • 34548501970 scopus 로고    scopus 로고
    • Regulation of the alpha-crystallin gene acr2 by the MprAB two-component system of Mycobacterium tuberculosis
    • Pang X, Howard S T. Regulation of the alpha-crystallin gene acr2 by the MprAB two-component system of Mycobacterium tuberculosis. J Bacteriol, 2007, 189: 6213-6221.
    • (2007) J Bacteriol , vol.189 , pp. 6213-6221
    • Pang, X.1    Howard, S.T.2
  • 35
    • 11144346285 scopus 로고    scopus 로고
    • Identification and characterization of a regulatory sequence recognized by Mycobacterium tuberculosis persistence regulator MprA
    • He H, Zahrt T C. Identification and characterization of a regulatory sequence recognized by Mycobacterium tuberculosis persistence regulator MprA. J Bacteriol, 2005, 187: 202-212.
    • (2005) J Bacteriol , vol.187 , pp. 202-212
    • He, H.1    Zahrt, T.C.2
  • 36
    • 34547458490 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor
    • Kumar A, Toledo J C, Patel R P, et al. Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor. Proc Natl Acad Sci USA, 2007, 104: 11568-11573.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11568-11573
    • Kumar, A.1    Toledo, J.C.2    Patel, R.P.3
  • 37
    • 3042713693 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis dosRS two-component system is induced by multiple stresses
    • Kendall S L, Movahedzadeh F, Rison S C, et al. The Mycobacterium tuberculosis dosRS two-component system is induced by multiple stresses. Tuberculosis, 2004, 84: 247-255.
    • (2004) Tuberculosis , vol.84 , pp. 247-255
    • Kendall, S.L.1    Movahedzadeh, F.2    Rison, S.C.3
  • 38
    • 10744233580 scopus 로고    scopus 로고
    • Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis
    • Malhotra V, Sharma D, Ramanathan V D, et al. Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis. FEMS Microbiol Lett, 2004, 231: 237-245.
    • (2004) FEMS Microbiol Lett , vol.231 , pp. 237-245
    • Malhotra, V.1    Sharma, D.2    Ramanathan, V.D.3
  • 39
    • 62449219456 scopus 로고    scopus 로고
    • Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models
    • Converse P J, Karakousis P C, Klinkenberg L G, et al. Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models. Infect Immun, 2009, 77: 1230-1237.
    • (2009) Infect Immun , vol.77 , pp. 1230-1237
    • Converse, P.J.1    Karakousis, P.C.2    Klinkenberg, L.G.3
  • 40
    • 0038349268 scopus 로고    scopus 로고
    • Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis
    • Park H D, Guinn K M, Harrell M I, et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol Microbiol, 2003, 48: 833-843.
    • (2003) Mol Microbiol , vol.48 , pp. 833-843
    • Park, H.D.1    Guinn, K.M.2    Harrell, M.I.3
  • 41
    • 0026544871 scopus 로고
    • KdpD and KdpE, proteins that control expression of the kdpABC operon, are members of the two-component sensor-effector class of regulators
    • Walderhaug M O, Polarek J W, Voelkner P, et al. KdpD and KdpE, proteins that control expression of the kdpABC operon, are members of the two-component sensor-effector class of regulators. J Bacteriol, 1992, 174: 2152-2159.
    • (1992) J Bacteriol , vol.174 , pp. 2152-2159
    • Walderhaug, M.O.1    Polarek, J.W.2    Voelkner, P.3
  • 42
    • 0037329291 scopus 로고    scopus 로고
    • Interaction of the sensor module of Mycobacterium tuberculosis H37Rv KdpD with members of the Lpr family
    • Steyn A J, Joseph J, Bloom B R. Interaction of the sensor module of Mycobacterium tuberculosis H37Rv KdpD with members of the Lpr family. Mol Microbiol, 2003, 47: 1075-1089.
    • (2003) Mol Microbiol , vol.47 , pp. 1075-1089
    • Steyn, A.J.1    Joseph, J.2    Bloom, B.R.3
  • 43
    • 3142574627 scopus 로고    scopus 로고
    • Global expression analysis of two-component system regulator genes during Mycobacterium tuberculosis growth in human macrophages
    • Haydel S E, Clark-Curtiss J E. Global expression analysis of two-component system regulator genes during Mycobacterium tuberculosis growth in human macrophages. FEMS Microbiol Lett, 2004, 236: 341-347.
    • (2004) FEMS Microbiol Lett , vol.236 , pp. 341-347
    • Haydel, S.E.1    Clark-Curtiss, J.E.2
  • 44
    • 34249066244 scopus 로고    scopus 로고
    • Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: Identification of a novel wax ester
    • Bacon J, Dover L G, Hatch K A, et al. Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: Identification of a novel wax ester. Microbiology, 2007, 153: 1435-1444.
    • (2007) Microbiology , vol.153 , pp. 1435-1444
    • Bacon, J.1    Dover, L.G.2    Hatch, K.A.3
  • 45
    • 0036270739 scopus 로고    scopus 로고
    • Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling
    • Betts J C, Lukey P T, Robb L C, et al. Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol Microbiol, 2002, 43: 717-731.
    • (2002) Mol Microbiol , vol.43 , pp. 717-731
    • Betts, J.C.1    Lukey, P.T.2    Robb, L.C.3
  • 46
    • 0029981245 scopus 로고    scopus 로고
    • A stationary-phase stress-response sigma factor from Mycobacterium tuberculosis
    • DeMaio J, Zhang Y, Ko C, et al. A stationary-phase stress-response sigma factor from Mycobacterium tuberculosis. Proc Natl Acad Sci USA, 1996, 93: 2790-2794.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2790-2794
    • Demaio, J.1    Zhang, Y.2    Ko, C.3
  • 47
    • 10744220645 scopus 로고    scopus 로고
    • Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis
    • Geiman D E, Kaushal D, Ko C, et al. Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis. Infect Immun, 2004, 72: 1733-1745.
    • (2004) Infect Immun , vol.72 , pp. 1733-1745
    • Geiman, D.E.1    Kaushal, D.2    Ko, C.3
  • 48
    • 33645532080 scopus 로고    scopus 로고
    • Posttranslational regulation of Mycobacterium tuberculosis extracytoplasmic-function sigma factor sigma L and roles in virulence and in global regulation of gene expression
    • Dainese E, Rodrigue S, Delogu G, et al. Posttranslational regulation of Mycobacterium tuberculosis extracytoplasmic-function sigma factor sigma L and roles in virulence and in global regulation of gene expression. Infect Immun, 2006, 74: 2457-2461.
    • (2006) Infect Immun , vol.74 , pp. 2457-2461
    • Dainese, E.1    Rodrigue, S.2    Delogu, G.3
  • 49
    • 34249797287 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1
    • Williams E P, Lee J H, Bishai W R, et al. Mycobacterium tuberculosis SigF regulates genes encoding cell wall-associated proteins and directly regulates the transcriptional regulatory gene phoY1. J Bacteriol, 2007, 189: 4234-4242.
    • (2007) J Bacteriol , vol.189 , pp. 4234-4242
    • Williams, E.P.1    Lee, J.H.2    Bishai, W.R.3
  • 50
    • 0034805644 scopus 로고    scopus 로고
    • The alternative sigma factor SigH regulates major components of oxidative and heat stress responses in Mycobacterium tuberculosis
    • Raman S, Song T, Puyang X, et al. The alternative sigma factor SigH regulates major components of oxidative and heat stress responses in Mycobacterium tuberculosis. J Bacteriol, 2001, 183: 6119-6125.
    • (2001) J Bacteriol , vol.183 , pp. 6119-6125
    • Raman, S.1    Song, T.2    Puyang, X.3
  • 51
    • 0036065206 scopus 로고    scopus 로고
    • Role of the extracytoplasmic-function sigma factor sigma(H) in Mycobacterium tuberculosis global gene expression
    • Manganelli R, Voskuil M I, Schoolnik G K, et al. Role of the extracytoplasmic-function sigma factor sigma(H) in Mycobacterium tuberculosis global gene expression. Mol Microbiol, 2002, 45: 365-374.
    • (2002) Mol Microbiol , vol.45 , pp. 365-374
    • Manganelli, R.1    Voskuil, M.I.2    Schoolnik, G.K.3
  • 52
    • 0032881104 scopus 로고    scopus 로고
    • Characterization of a Mycobacterium tuberculosis homologue of the Streptomyces coelicolor whiB gene
    • Mulder N J, Zappe H, Steyn L M. Characterization of a Mycobacterium tuberculosis homologue of the Streptomyces coelicolor whiB gene. Tuber Lung Dis, 1999, 79: 299-308.
    • (1999) Tuber Lung Dis , vol.79 , pp. 299-308
    • Mulder, N.J.1    Zappe, H.2    Steyn, L.M.3
  • 53
    • 34547463011 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival
    • Singh A, Guidry L, Narasimhulu K V, et al. Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival. Proc Natl Acad Sci USA, 2007, 104: 11562-11567.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11562-11567
    • Singh, A.1    Guidry, L.2    Narasimhulu, K.V.3
  • 54
    • 70149116303 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response
    • Singh A, Crossman D K, Mai D, et al. Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response. PLoS Pathog, 2009, 5: e1000545.
    • (2009) PLoS Pathog , vol.5 , pp. 1000545
    • Singh, A.1    Crossman, D.K.2    Mai, D.3
  • 55
    • 33750439838 scopus 로고    scopus 로고
    • Regulation of Mycobacterium tuberculosis whiB3 in the mouse lung and macrophages
    • Banaiee N, Jacobs W R Jr, Ernst J D. Regulation of Mycobacterium tuberculosis whiB3 in the mouse lung and macrophages. Infect Immun, 2006, 74: 6449-6457.
    • (2006) Infect Immun , vol.74 , pp. 6449-6457
    • Banaiee, N.1    Jacobs Jr., W.R.2    Ernst, J.D.3
  • 56
    • 0032791894 scopus 로고    scopus 로고
    • Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis
    • Avarbock D, Salem J, Li L S, et al. Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis. Gene, 1999, 233: 261-269.
    • (1999) Gene , vol.233 , pp. 261-269
    • Avarbock, D.1    Salem, J.2    Li, L.S.3
  • 57
    • 0043192889 scopus 로고    scopus 로고
    • The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice
    • Dahl J L, Kraus C N, Boshoff H I, et al. The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice. Proc Natl Acad Sci USA, 2003, 100: 10026-10031.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10026-10031
    • Dahl, J.L.1    Kraus, C.N.2    Boshoff, H.I.3
  • 58
    • 0031930142 scopus 로고    scopus 로고
    • Mycobacterial stationary phase induced by low oxygen tension: Cell wall thickening and localization of the 16-kilodalton alpha-crystallin homolog
    • Cunningham A F, Spreadbury C L. Mycobacterial stationary phase induced by low oxygen tension: Cell wall thickening and localization of the 16-kilodalton alpha-crystallin homolog. J Bacteriol, 1998, 180: 801-808.
    • (1998) J Bacteriol , vol.180 , pp. 801-808
    • Cunningham, A.F.1    Spreadbury, C.L.2
  • 59
    • 0029785912 scopus 로고    scopus 로고
    • Stationary phase-associated protein expression in Mycobacterium tuberculosis: Function of the mycobacterial alpha-crystallin homolog
    • Yuan Y, Crane D D, Barry C E. Stationary phase-associated protein expression in Mycobacterium tuberculosis: Function of the mycobacterial alpha-crystallin homolog. J Bacteriol, 1996, 178: 4484-4492.
    • (1996) J Bacteriol , vol.178 , pp. 4484-4492
    • Yuan, Y.1    Crane, D.D.2    Barry, C.E.3
  • 60
    • 34447311357 scopus 로고    scopus 로고
    • Polyphosphate kinase is involved in stress-induced mprAB-sigE-rel signalling in mycobacteria
    • Sureka K, Dey S, Datta P, et al. Polyphosphate kinase is involved in stress-induced mprAB-sigE-rel signalling in mycobacteria. Mol Microbiol, 2007, 65: 261-276.
    • (2007) Mol Microbiol , vol.65 , pp. 261-276
    • Sureka, K.1    Dey, S.2    Datta, P.3
  • 61
    • 19744376797 scopus 로고    scopus 로고
    • Contribution of the Mycobacterium tuberculosis MmpL protein family to virulence and drug resistance
    • Domenech P, Reed M B, Barry C E. Contribution of the Mycobacterium tuberculosis MmpL protein family to virulence and drug resistance. Infect Immun, 2005, 73: 3492-3501.
    • (2005) Infect Immun , vol.73 , pp. 3492-3501
    • Domenech, P.1    Reed, M.B.2    Barry, C.E.3
  • 62
    • 75549086229 scopus 로고    scopus 로고
    • Identification of promoter-binding proteins of the fbp A and C genes in Mycobacterium tuberculosis
    • Romero I C, Mehaffy C, Burchmore R J, et al. Identification of promoter-binding proteins of the fbp A and C genes in Mycobacterium tuberculosis. Tuberculosis (Edinb), 2010, 90: 25-30.
    • (2010) Tuberculosis (Edinb) , vol.90 , pp. 25-30
    • Romero, I.C.1    Mehaffy, C.2    Burchmore, R.J.3
  • 63
    • 38749151604 scopus 로고    scopus 로고
    • Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network
    • Lee J H, Karakousis P C, Bishai W R. Roles of SigB and SigF in the Mycobacterium tuberculosis sigma factor network. J Bacteriol, 2008, 190: 699-707.
    • (2008) J Bacteriol , vol.190 , pp. 699-707
    • Lee, J.H.1    Karakousis, P.C.2    Bishai, W.R.3
  • 64
    • 69949100882 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth
    • Fontan P A, Voskuil M I, Gomez M, et al. The Mycobacterium tuberculosis sigma factor sigmaB is required for full response to cell envelope stress and hypoxia in vitro, but it is dispensable for in vivo growth. J Bacteriol, 2009, 191: 5628-5633.
    • (2009) J Bacteriol , vol.191 , pp. 5628-5633
    • Fontan, P.A.1    Voskuil, M.I.2    Gomez, M.3
  • 65
    • 45749106329 scopus 로고    scopus 로고
    • Not to wake a sleeping giant: New insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection
    • Lin M Y, Ottenhoff T H. Not to wake a sleeping giant: New insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection. Biol Chem, 2008, 389: 497-511.
    • (2008) Biol Chem , vol.389 , pp. 497-511
    • Lin, M.Y.1    Ottenhoff, T.H.2
  • 66
    • 34249882752 scopus 로고    scopus 로고
    • T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination
    • Geluk A, Lin M Y, van Meijgaarden K E, et al. T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination. Infect Immun, 2007, 75: 2914-2921.
    • (2007) Infect Immun , vol.75 , pp. 2914-2921
    • Geluk, A.1    Lin, M.Y.2    van Meijgaarden, K.E.3
  • 67
    • 0033566165 scopus 로고    scopus 로고
    • Therapy of tuberculosis in mice by DNA vaccination
    • Lowrie D B, Tascon R E, Bonato V L, et al. Therapy of tuberculosis in mice by DNA vaccination. Nature, 1999, 400: 269-271.
    • (1999) Nature , vol.400 , pp. 269-271
    • Lowrie, D.B.1    Tascon, R.E.2    Bonato, V.L.3
  • 68
    • 77952554229 scopus 로고    scopus 로고
    • DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions
    • Flores Valdez M A, Schoolnik G K. DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions. Tuberculosis, 2010, 90: 197-200.
    • (2010) Tuberculosis , vol.90 , pp. 197-200
    • Flores Valdez, M.A.1    Schoolnik, G.K.2
  • 69
    • 55049114750 scopus 로고    scopus 로고
    • Novel drug target strategies against Mycobacterium tuberculosis
    • Murphy D J, Brown J R. Novel drug target strategies against Mycobacterium tuberculosis. Curr Opin Microbiol, 2008, 11: 422-427.
    • (2008) Curr Opin Microbiol , vol.11 , pp. 422-427
    • Murphy, D.J.1    Brown, J.R.2
  • 70
    • 0347091999 scopus 로고    scopus 로고
    • M. tuberculosis persistence, latency, and drug tolerance
    • Gomez J E, McKinney J D. M. tuberculosis persistence, latency, and drug tolerance. Tuberculosis, 2004, 84: 29-44.
    • (2004) Tuberculosis , vol.84 , pp. 29-44
    • Gomez, J.E.1    McKinney, J.D.2
  • 71
    • 77955461146 scopus 로고    scopus 로고
    • Imaging tuberculosis with endogenous β-lactamase reporter enzyme fluorescence in live mice
    • Kong Y, Yao H, Ren H, et al. Imaging tuberculosis with endogenous β-lactamase reporter enzyme fluorescence in live mice. Proc Natl Acad Sci USA, 2010, 107: 12239-12244.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 12239-12244
    • Kong, Y.1    Yao, H.2    Ren, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.