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Volumn 16, Issue 5, 2011, Pages 557-568

Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA A receptor Β2 subunit

Author keywords

epigenetics; imprinting; positive selection; schizophrenia

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; BISULFITE; MESSENGER RNA;

EID: 79955480276     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2010.47     Document Type: Article
Times cited : (48)

References (48)
  • 1
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a Complex Trait: Evidence from a Meta-analysis of Twin Studies
    • DOI 10.1001/archpsyc.60.12.1187
    • Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 2003; 60: 1187-1192. (Pubitemid 37494071)
    • (2003) Archives of General Psychiatry , vol.60 , Issue.12 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 2
    • 0034097718 scopus 로고    scopus 로고
    • Twin studies in schizophrenia with special emphasis on concordance figures
    • DOI 10.1002/(SI CI)1096-86 28(20002 1)97:1<4::A ID-AJM G2>3.0.CO;2-J
    • Kringlen E. Twin studies in schizophrenia with special emphasis on concordance figures. Am J Med Genet 2000; 97: 4-11. (Pubitemid 30257321)
    • (2000) American Journal of Medical Genetics - Seminars in Medical Genetics , vol.97 , Issue.1 , pp. 4-11
    • Kringlen, E.1
  • 3
    • 0033956237 scopus 로고    scopus 로고
    • Schizophrenia: Genes and environment
    • DOI 10.1016/S0006-3223(99)00289-9, PII S0006322399002899
    • Tsuang M. Schizophrenia: genes and environment. Biol Psychiatry 2000; 47: 210-220. (Pubitemid 30077397)
    • (2000) Biological Psychiatry , vol.47 , Issue.3 , pp. 210-220
    • Tsuang, M.1
  • 6
    • 0345628008 scopus 로고    scopus 로고
    • Polymorphic imprinting of the serotonin-2A (5-HT(2A)) receptor gene in human adult brain
    • DOI 10.1016/S0169-328X(98)00146-6, PII S0169328X98001466
    • Bunzel R, Blumcke I, Cichon S, Normann S, Schramm J, Propping P et al. Polymorphic imprinting of the serotonin-2A (5-HT2A) receptor gene in human adult brain. Mol Brain Res 1998; 59: 90-92. (Pubitemid 28408451)
    • (1998) Molecular Brain Research , vol.59 , Issue.1 , pp. 90-92
    • Bunzel, R.1    Blumcke, I.2    Cichon, S.3    Normann, S.4    Schramm, J.5    Propping, P.6    Nothen, M.M.7
  • 8
    • 1542718627 scopus 로고    scopus 로고
    • A receptors: Building the bridge between subunit mRNAs, their promoters, and cognate transcription factors
    • DOI 10.1016/j.pharmthera.2003.12.002, PII S016372580400004X
    • Steiger JL, Russek SJ. GABAA receptors: building the bridge between subunit mRNAs, their promoters, and cognate transcription factors. Pharmacol Ther 2004; 101: 259-281. (Pubitemid 38340862)
    • (2004) Pharmacology and Therapeutics , vol.101 , Issue.3 , pp. 259-281
    • Steiger, J.L.1    Russek, S.J.2
  • 9
    • 0015422513 scopus 로고
    • Prospects for research on schizophrenia. An hypotheses suggesting that there is a defect in the GABA system in schizophrenia
    • Roberts E. Prospects for research on schizophrenia. An hypotheses suggesting that there is a defect in the GABA system in schizophrenia. Neurosci Res Program Bull 1972; 10: 468-482.
    • (1972) Neurosci Res Program Bull , vol.10 , pp. 468-482
    • Roberts, E.1
  • 12
    • 0030980118 scopus 로고    scopus 로고
    • Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families
    • Straub RE, MacLean CJ, O'Neill FA, Walsh D, Kendler KS. Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families. Mol Psychiatry 1997; 2: 148-155. (Pubitemid 27166035)
    • (1997) Molecular Psychiatry , vol.2 , Issue.2 , pp. 148-155
    • Straub, R.E.1    MacLean, C.J.2    O'Neill, F.A.3    Walsh, D.4    Kendler, K.S.5
  • 18
    • 33845255282 scopus 로고    scopus 로고
    • 2 subunit with different electrophysiological properties: Differential expression and genotypical correlations in schizophrenia
    • DOI 10.1038/sj.mp.4001899, PII 4001899
    • Zhao C, Xu Z, Chen J, Yu Z, Tong KL, Lo WS et al. Two isoforms of GABAA receptor b2 subunit with different electrophysiological properties: differential expression and genotypical correlations in schizophrenia. Mol Psychiatry 2006; 11: 1092-1105. (Pubitemid 44863434)
    • (2006) Molecular Psychiatry , vol.11 , Issue.12 , pp. 1092-1105
    • Zhao, C.1    Xu, Z.2    Chen, J.3    Yu, Z.4    Tong, K.-L.5    Lo, W.-S.6    Pun, F.W.7    Ng, S.-K.8    Tsang, S.-Y.9    Xue, H.10
  • 19
    • 70349453711 scopus 로고    scopus 로고
    • Alternativesplicing in the exon-10 region of GABAA receptor b2 subunit gene: Relationships between novel isoforms and psychotic disorders
    • Zhao C, Xu Z, Wang F, Chen J, Ng SK, Wong PW et al. Alternativesplicing in the exon-10 region of GABAA receptor b2 subunit gene: relationships between novel isoforms and psychotic disorders. PLoS ONE 2009; 4: e6977.
    • (2009) PLoS ONE , vol.4
    • Zhao, C.1    Xu, Z.2    Wang, F.3    Chen, J.4    Ng, S.K.5    Wong, P.W.6
  • 21
    • 77949716888 scopus 로고    scopus 로고
    • A recombination hotspot in a schizophrenia-associated region of GABRB2
    • Ng SK, Lo WS, Pun FW, Zhao C, Yu Z, Chen J et al. A recombination hotspot in a schizophrenia-associated region of GABRB2. PLoS ONE 2010; 5: e9547.
    • (2010) PLoS ONE , vol.5
    • Ng, S.K.1    Lo, W.S.2    Pun, F.W.3    Zhao, C.4    Yu, Z.5    Chen, J.6
  • 25
    • 0036382921 scopus 로고    scopus 로고
    • Dopamine D4 receptor and tyrosine hydroxylase genes in bipolar disorder: Evidence for a role of DRD4
    • Muglia P, Petronis A, Mundo E, Lander S, Cate T, Kennedy JL. Dopamine D4 receptor and tyrosine hydroxylase genes in bipolar disorder: evidence for a role of DRD4. Mol Psychiatry 2002; 7: 860-866.
    • (2002) Mol Psychiatry , vol.7 , pp. 860-866
    • Muglia, P.1    Petronis, A.2    Mundo, E.3    Lander, S.4    Cate, T.5    Kennedy, J.L.6
  • 26
    • 0035234557 scopus 로고    scopus 로고
    • Genomic imprinting: Parental influence on the genome
    • DOI 10.1038/35047554
    • Reik W, Walter J. Genomic imprinting: parental influence on the genome. Nat Rev Genet 2001; 2: 21-32. (Pubitemid 33674766)
    • (2001) Nature Reviews Genetics , vol.2 , Issue.1 , pp. 21-32
    • Reik, W.1    Walter, J.2
  • 28
    • 47149116702 scopus 로고    scopus 로고
    • CpG island density and its correlations with genomic features in mammalian genomes
    • Han L, Su B, Li WH, Zhao Z. CpG island density and its correlations with genomic features in mammalian genomes. Genome Biol 2008; 9: R79.
    • (2008) Genome Biol , vol.9
    • Han, L.1    Su, B.2    Li, W.H.3    Zhao, Z.4
  • 29
    • 35549001312 scopus 로고    scopus 로고
    • Genomic imprinting effects on brain development and function
    • DOI 10.1038/nrn2235, PII NRN2235
    • Wilkinson LS, Davies W, Isles AR. Genomic imprinting effects on brain development and function. Nat Rev Neurosci 2007; 8: 832-843. (Pubitemid 350006217)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.11 , pp. 832-843
    • Wilkinson, L.S.1    Davies, W.2    Isles, A.R.3
  • 30
    • 0034255591 scopus 로고    scopus 로고
    • Imprinted genes, cognition and behaviour
    • DOI 10.1016/S1364-6613(00)01504-7, PII S1364661300015047
    • Isles AR, Wilkinson LS. Imprinted genes, cognition and behaviour. Trends Cogn Sci 2000; 4: 309-318. (Pubitemid 30488177)
    • (2000) Trends in Cognitive Sciences , vol.4 , Issue.8 , pp. 309-318
    • Isles, A.R.1    Wilkinson, L.S.2
  • 31
    • 0035777024 scopus 로고    scopus 로고
    • Genome organization, function, and imprinting in Prader-Willi and Angelman syndromes
    • DOI 10.1146/annurev.genom.2.1.153
    • Nicholls RD, Knepper JL. Genome organization, function, and imprinting in Prader-Willi and Angelman syndromes. Annu Rev Genomics Hum Genet 2001; 2: 153-175. (Pubitemid 35265004)
    • (2001) Annual Review of Genomics and Human Genetics , vol.2 , pp. 153-175
    • Nicholls, R.D.1    Knepper, J.L.2
  • 33
    • 0034125860 scopus 로고    scopus 로고
    • The genes for major psychosis: Aberrant sequence or regulation?
    • DOI 10.1016/S0893-133X(00)00127-5, PII S0893133X00001275
    • Petronis A. The genes for major psychosis: aberrant sequence or regulation? Neuropsychopharmacology 2000; 23: 1-12. (Pubitemid 30408307)
    • (2000) Neuropsychopharmacology , vol.23 , Issue.1 , pp. 1-12
    • Petronis, A.1
  • 34
    • 0035189109 scopus 로고    scopus 로고
    • Paternal factors and schizophrenia risk: De novo mutations and imprinting
    • Malaspina D. Paternal factors and schizophrenia risk: de novo mutations and imprinting. Schizoph Bull 2001; 27: 379-393. (Pubitemid 33081692)
    • (2001) Schizophrenia Bulletin , vol.27 , Issue.3 , pp. 379-393
    • Malaspina, D.1
  • 36
    • 34249661229 scopus 로고    scopus 로고
    • Parent-of-origin effect and genomic imprinting of the HTR2A receptor gene T102C polymorphism in psychosis
    • DOI 10.1016/j.psychres.2006.11.010, PII S0165178106003726
    • De Luca V, Likhodi O, Kennedy JL, Wong AHC. Parent-of-origin effect and genomic imprinting of the HTR2A receptor gene T102C polymorphism in psychosis. Psychiatry Res 2007; 151: 243-248. (Pubitemid 46829418)
    • (2007) Psychiatry Research , vol.151 , Issue.3 , pp. 243-248
    • De Luca, V.1    Likhodi, O.2    Kennedy, J.L.3    Wong, A.H.C.4
  • 40
    • 0032213597 scopus 로고    scopus 로고
    • The role of gender differences in the reduction of etiologic heterogeneity in schizophrenia
    • DOI 10.1016/S0272-7358(98)00008-7, PII S0272735898000087
    • Salem JE, Kring AM. The role of gender differences in the reduction of etiologic heterogeneity in schizophrenia. Clin Psychol Rev 1998; 18: 795-819. (Pubitemid 28512550)
    • (1998) Clinical Psychology Review , vol.18 , Issue.7 , pp. 795-819
    • Salem, J.E.1    Kring, A.M.2
  • 41
    • 0141428983 scopus 로고    scopus 로고
    • Sex-dependent effects of schizophrenia: An MRI study of gyral folding, and cortical and white matter volume
    • DOI 10.1016/S0925-4927(03)00076-3
    • Highley JR, DeLisi LE, Roberts N, Webb JA, Relja M, Razi K et al. Sex-dependent effects of schizophrenia: an MRI study of gyral folding, and cortical and white matter volume. Psychiatry Res 2003; 124: 11-23. (Pubitemid 37159330)
    • (2003) Psychiatry Research - Neuroimaging , vol.124 , Issue.1 , pp. 11-23
    • Highley, J.R.1    DeLisi, L.E.2    Roberts, N.3    Webb, J.A.4    Relja, M.5    Razi, K.6    Crow, T.J.7
  • 42
    • 33747871713 scopus 로고    scopus 로고
    • Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: Dissection of epigenetic and genetic factors
    • DOI 10.1093/hmg/ddl192
    • Pinsonneault JK, Papp AC, Sadee W. Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: dissection of epigenetic and genetic factors. Hum Mol Genet 2006; 15: 2636-2649. (Pubitemid 44288692)
    • (2006) Human Molecular Genetics , vol.15 , Issue.17 , pp. 2636-2649
    • Pinsonneault, J.K.1    Papp, A.C.2    Sadee, W.3
  • 44
    • 0025958320 scopus 로고
    • Genomic imprinting in mammalian development: A parental tug-of-war
    • Moore T, Haig D. Genomic imprinting in mammalian development: a parental tug-of-war. Trends Genet 1991; 7: 45-49. (Pubitemid 121001901)
    • (1991) Trends in Genetics , vol.7 , Issue.2 , pp. 45-49
    • Moore, T.1    Haig, D.2
  • 45
    • 0028224130 scopus 로고
    • Genomic imprinting - Defusing the ovarian time bomb
    • DOI 10.1016/0168-9525(94)90212-7
    • Varmuza S, Mann M. Genomic imprinting-defusing the ovarian time bomb. Trends Genet 1994; 10: 118-123. (Pubitemid 24107643)
    • (1994) Trends in Genetics , vol.10 , Issue.4 , pp. 118-123
    • Varmuza, S.1    Mann, M.2
  • 46
    • 0036096835 scopus 로고    scopus 로고
    • A rheostat model for a rapid and reversible form of imprinting-dependent evolution
    • DOI 10.1086/340969
    • Beaudet AL, Jiang YH. A rheostat model for a rapid and reversible form of imprinting-dependent evolution. Am J Hum Genet 2002; 70: 1389-1397. (Pubitemid 34533887)
    • (2002) American Journal of Human Genetics , vol.70 , Issue.6 , pp. 1389-1397
    • Beaudet, A.L.1    Jiang, Y.-H.2
  • 47
    • 35848963738 scopus 로고    scopus 로고
    • Positive selection within the schizophrenia-associated GABAA receptor b2 gene
    • Lo WS, Xu Z, Yu Z, Pun FW, Ng SK, Chen J et al. Positive selection within the schizophrenia-associated GABAA receptor b2 gene. PLoS ONE 2007; 2: e462.
    • (2007) PLoS ONE , vol.2
    • Lo, W.S.1    Xu, Z.2    Yu, Z.3    Pun, F.W.4    Ng, S.K.5    Chen, J.6
  • 48
    • 51649127761 scopus 로고    scopus 로고
    • Clozapine and sulpiride but not haloperidol or olanzapine activate ' brain DNA demethylation
    • Dong E, Nelson M, Grayson DR, Costa E, Guidotti A. Clozapine and sulpiride but not haloperidol or olanzapine activate ' brain DNA demethylation. Proc Natl Acad Sci USA 2008; 105: 13614-13619.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13614-13619
    • Dong, E.1    Nelson, M.2    Grayson, D.R.3    Costa, E.4    Guidotti, A.5


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