N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 9, 2011, Pages 2850-2858

  Wicek, Małgorzata ^a   Kottke, Tim ^b   Ligneau, Xavier ^c   Schunack, Walter ^d   Seifert, Roland ^e   Stark, Holger ^b   Handzlik, Jadwiga ^a   Kieć Kononowicz, Katarzyna ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b GOETHE UNIVERSITY   (Germany)

^c Bioprojet Biotech   (France)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Histamine H3 receptor; Histamine H4 receptor; Imidazole carbamates

Indexed keywords

2 CYCLOHEXYLETHANAMINE; 3 (1H IMIDAZOL 4 YL)PROPYL 2 CYCLOHEXYLBUTYLCARBAMATE HYDROGEN MALEATE; 3 (1H IMIDAZOL 4 YL)PROPYL 2 CYCLOHEXYLETHYLCARBAMATE HYDROGEN MALEATE; 3 (1H IMIDAZOL 4 YL)PROPYL 2 CYCLOHEXYLPROPYLCARBAMATE HYDROGEN MALEATE; 3 (1H IMIDAZOL 4 YL)PROPYL 3,7 DIMETHYLOCTA 2,6 DIENYLCARBAMATE HYDROGEN MALEATE; 3 (1H IMIDAZOL 4 YL)PROPYL BUT 2 ENYLCARBAMATE HYDROGEN MALEATE; 3 (1H IMIDAZOL 4 YL)PROPYL HEX 2 ENYLCARBAMATE HYDROGEN MALEATE; 3 (1H IMIDAZOL 4 YL)PROPYL PENT 2 ENYLCARBAMATE HYDROGEN MALEATE; 3 CYCLOHEXYLPROPANAMINE; 4 CYCLOHEXYLBUTANAMINE; BUT 2 ENAMINE; CIPROXIFAN; CLOBENPROPIT; HEX 2 ENAMINE; HEX 3 ENAMINE; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; HISTAMINE H4 RECEPTOR; IMETIT; N [1 (2 CYCLOHEXYL)ETHYL]PHTHALIMIDE; N [1 (3 CYCLOHEXYL)PROPYL]PHTHALIMIDE; N [1 (4 CYCLOHEXYL)BUTYL]PHTHALIMIDE; N(3,7 DIMETHYL 2,6 OCTADIENYL)PHTHALIMIDE; N(BUT 2 ENYL)PHTHALIMIDE; N(HEX 2 ENYL)PHTHALIMIDE; N(HEX 3 ENYL)PHTHALIMIDE; N(PENT 2 ENYL)PHTHALIMIDE; PENT 2 ENAMINE; THIOPERAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG MECHANISM; DRUG PENETRATION; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; GUINEA PIG; IN VIVO STUDY; LIGAND BINDING; MOUSE; NONHUMAN; PHARMACOPHORE; PROTEIN EXPRESSION; PROTEIN QUATERNARY STRUCTURE;

CARBAMATES; HISTAMINE ANTAGONISTS; HUMANS; LIGANDS; PHTHALIMIDES; PROTEIN ISOFORMS; RECEPTORS, HISTAMINE H3;

CAVIA; MUS;

EID: 79955472092     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.03.046     Document Type: Article

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