Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity

Journal of Medicinal Chemistry

Volumn 39, Issue 5, 1996, Pages 1157-1163

  Stark, Holger ^a   Purand, Katja ^a   Ligneau, Xavier ^b   Rouleau, Agnès ^c   Arrang, Jean Michel ^c   Garbarg, Monique ^c   Schwartz, Jean Charles ^c   Schunack, Walter ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b Laboratoire Bioprojet   (France)

^c CENTRE PAUL BROCA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BURIMAMIDE; CARBAMIC ACID DERIVATIVE; CLOBENPROPIT; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR ANTAGONIST; THIOAMIDE; THIOPERAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CYTOSTASIS; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANIMALS; CARBAMATES; CEREBRAL CORTEX; GUINEA PIGS; HISTAMINE; HISTAMINE ANTAGONISTS; IMIDAZOLES; MICE; MOLECULAR STRUCTURE; PHENYLCARBAMATES; RATS; RECEPTORS, HISTAMINE H1; RECEPTORS, HISTAMINE H2; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTOSOMES;

EID: 0029877782     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9507688     Document Type: Article

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