In vitro Differentiated adult human liver progenitor cells display mature hepatic metabolic functions: A potential tool for in vitro pharmacotoxicological testing

Cell Transplantation

Volumn 20, Issue 2, 2011, Pages 287-302

  Khuu, Dung Ngoc ^a   Scheers, Isabelle ^a   Ehnert, Sabrina ^b   Jazouli, Nawal ^a   Nyabi, Omar ^a   Buc Calderon, Pedro ^a   Meulemans, Ann ^c   Nussler, Andreas ^b   Sokal, Etienne ^a   Najimi, Mustapha ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Hepatic stem cells; Hepatocyte differentiation; Mesenchymal cells; Metabolic activity; Tissue specific stem cells

Indexed keywords

3 [ 2 (N,N DIETHYLAMINO)ETHYL] 7 HYDROXY 4 METHYLCOUMARIN; 7 HYDROXY 4 (TRIFLUOROMETHYL)COUMARIN; AMINO ACID; AMMONIA; AMMONIUM CHLORIDE; ARGINASE; COUMARIN DERIVATIVE; CYTOCHROME; CYTOCHROME P450 3A4; DRUG METABOLIZING ENZYME; FLUORESCEIN; GLUCOSE; GLUCOSE 6 PHOSPHATASE; MESSENGER RNA; RESORUFIN; UMBELLIFERONE; UNCLASSIFIED DRUG; UREA;

ADULT; ADULT DERIVED HUMAN LIVER PROGENITOR CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DETOXIFICATION; DRUG METABOLISM; ENZYME ACTIVITY; FLUORESCENCE ANALYSIS; GLUCONEOGENESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER; LIVER CELL; LIVER METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TOXICITY TESTING;

ADULT; ADULT STEM CELLS; AMINO ACIDS; ANIMALS; CELL DIFFERENTIATION; CYTOCHROME P-450 CYP3A; GLUCONEOGENESIS; GLUCOSE; HUMANS; LIVER; METABOLIC DETOXICATION, PHASE I; METABOLIC DETOXICATION, PHASE II; QUATERNARY AMMONIUM COMPOUNDS; RATS; STEM CELLS; TOXICITY TESTS; UP-REGULATION; UREA;

EID: 79955445199     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368910X516655     Document Type: Article

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