A microtiterplate-based screening assay to assess diverse effects on cytochrome P450 enzyme activities in primary rat hepatocytes by various compounds

Assay and Drug Development Technologies

Volumn 3, Issue 1, 2005, Pages 27-38

  Schaeffner, I ^a   Petters, J ^a   Aurich, H ^a   Frohberg, P ^a   Christ, Bruno ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; BETA NAPHTHOFLAVONE; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 2B; LIPOXYGENASE INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR; RESVERATROL; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL CULTURE; CELL SCREENING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME INHIBITION; FLUORESCENCE SPECTROSCOPY; LIVER CELL; LONG TERM EXPOSURE; MALE; MICROTITER PLATE ASSAY; NONHUMAN; PROTEIN DETERMINATION; RAT;

ANIMALS; BIOLOGICAL ASSAY; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLAVONES; HEPATOCYTES; MALE; MINIATURIZATION; RATS; RATS, WISTAR; ROBOTICS;

EID: 17344362884     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2005.3.27     Document Type: Article

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