Inhibition of Wnt/β-catenin signaling by p38 MAP kinase inhibitors is explained by cross-reactivity with casein kinase Iδ/ε

Chemistry and Biology

Volumn 18, Issue 4, 2011, Pages 485-494

  Verkaar, Folkert ^a,b   Van Der Doelen, Antoon A ^a   Smits, Jos F M ^b   Blankesteijn, W Matthijs ^b   Zaman, Guido J R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BETA CATENIN; CASEIN KINASE I; CASEIN KINASE IDELTA; CASEIN KINASE IEPSILON; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE INHIBITOR; WNT PROTEIN;

ARTICLE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; ENZYME SPECIFICITY; HUMAN; METABOLISM; SIGNAL TRANSDUCTION;

ANTI-INFLAMMATORY AGENTS; BETA CATENIN; CASEIN KINASE I; CASEIN KINASE IDELTA; CASEIN KINASE IEPSILON; CELL LINE; DRUG EVALUATION, PRECLINICAL; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; WNT PROTEINS;

EID: 79955443962     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.01.015     Document Type: Article

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